• Proceedings of the Korean Geotechical Society Conference
• /
• 2010.09b
• /
• pp.61-67
• /
• 2010

Thick soft clay deposits which are generally located at the west and south coast of the Korean peninsula have complicated characteristics according to their orientation and formation history. Thus, several geotechnical problems could possibly occur when those soft clay deposits are used as foundations for marine structures. Deep cement mixing (DCM) method is one of the most widely used soft soil improvement method for various marine structures, nowadays. DCM method injects binders such as cement into the soft ground directly and mixes with the in-situ soil to improve the strength and other geotechnical properties sufficiently. However, the natural impacts induced by dynamic motions such as ocean waves, wind, typhoon, and tusnami give significant influences on the stability of marine structures and their underlaying foundations. Thus, the dynamic properties become important design criteria to insure the seismic stability of marine structures. In this study, the dynamic behavior of cemented Busan clay is evaluated. Laboratory unconfined compression test and resonant column test are performed on natural in-situ soil and cement mixed specimens to confirm the strength and strain-dependent dynamic behavior variation induced by cement mixing treatment. Results show that the unconfined compressive strength and shear modulus increase with curing time and cement content increment. Finally, the optimized cement mixing ratio for sufficient dynamic stability is obtained through this study. The results of this study are expected to be widely used to improve the reliability of seismic design for marine structures.

• Nuclear Engineering and Technology
• /
• v.51 no.8
• /
• pp.2042-2049
• /
• 2019

Ten gizzard and three flesh samples of the broiler were collected from different locations in Tehsil Gujar Khan District Rawalpindi, Pakistan. The samples were dried, crushed and ground. Pellets were prepared by pressing the powder of the samples and that of the Bovine liver 1577c reference material obtained from NIST, USA. Proton induced X-ray emission (PIXE) installed at National Center for Physics, Islamabad, Pakistan has been used as a reliable and improved technique to determine concentration of various major/trace and toxic elements e.g. S, Cl, K, Ca, Cl, Fe, Cu, Mn, Co, Zn, Ti, Cd, Ga, Cr, V and Ni, in the Gizzard and Flesh samples of the broiler. The concentrations of all the detected elements in the samples are statistically significant. The certified and measured values of the elements in the reference material were in agreement with each other within a deviation of 7%. S, Cl, K and Ca are within tolerable limits and are good for human consumption. Ti, V, Cr, Mn, Fe, Co, Ni, Cu and Zn were more than the acceptable limits of World Health Organization, WHO whereas Ga, As, Sn, Sb and Pb are not detected in most of the samples.

• Journal of the Korean Society of Hazard Mitigation
• /
• v.6 no.4 s.23
• /
• pp.7-14
• /
• 2006

The tilting-train being operated in pre-existing rail road has a different running mechanism compared to currently operated trains. Therefore, it needs to investigate the evaluation of the track performance, the stability of the tilting-train in operating condition, and the stability of the roadbed. In this study, when the tilting train is operated in the rail joint with the allowable velocity limited by the track performance and the stability of the tilting-train, the settlement of the roadbed has been evaluated by using numerical analysis. The loading on the ground surface generated by the operating tilting-train generates the settlement of the roadbed. The settlement induced by the tilting-train loading has been compared to the allowable settlement and the factor of safety defined by the ratio of the allowable settlement to the settlement generated by the applied loading is evaluated.

• Tuberculosis and Respiratory Diseases
• /
• v.56 no.3
• /
• pp.315-320
• /
• 2004

Gemcitabine is an effective newly developed chemotherapeutic agent, which is increasingly being used to treat non-small cell lung, ovarian and breast cancers. Pulmonary toxicity is usually self-limiting mild dyspnea, bronchospasm, but severe pulmonary toxicity is rarely reported. Herein, we report drug induced interstitial lung disease associated with gemcitabine treatment. High resolution computerized tomogram (HRCT) showed an increased ground glass opacity and thickened septal lines. The patient showed a rapid good response with prednisolone treatment.

• Molecules and Cells
• /
• v.37 no.1
• /
• pp.31-35
• /
• 2014

Induced pluripotent stem cells (iPSCs) are capable of unlimited self-renewal and can give rise to all three germ layers, thereby providing a new platform with which to study mammalian development and epigenetic reprogramming. However, iPSC generation may result in subtle epigenetic variations, such as the aberrant methylation of the Dlk1-Dio3 locus, among the clones, and this heterogeneity constitutes a major drawback to harnessing the full potential of iPSCs. Vitamin C has recently emerged as a safeguard to ensure the normal imprinting of the Dlk1-Dio3 locus during reprogramming. Here, we show that vitamin C exerts its effect in a manner that is independent of the reprogramming kinetics. Moreover, we demonstrate that reprogramming cells under 2i conditions leads to the early upregulation of Prdm14, which in turn results in a highly homogeneous population of authentic pluripotent colonies and prevents the abnormal silencing of the Dlk1-Dio3 locus.

• Earthquakes and Structures
• /
• v.13 no.4
• /
• pp.377-386
• /
• 2017

Earthquake-induced pounding damages to building structures were repeatedly observed in many previous major earthquakes. Extensive researches have been carried out in this field. Previous studies mainly focused on the regular shaped buildings and each building was normally simplified as a single-degree-of-freedom (SDOF) system or a multi-degree-of-freedom (MDOF) system by assuming the masses of the building lumped at the floor levels. The researches on the pounding responses between irregular asymmetric buildings are rare. For the asymmetric buildings subjected to earthquake loading, torsional vibration modes of the structures are excited, which in turn may significantly change the structural responses. Moreover, contact element was normally used to consider the pounding phenomenon in previous studies, which may result in inaccurate estimations of the structural responses since this method is based on the point-to-point pounding assumption with the predetermined pounding locations. In reality, poundings may take place between any locations. In other words, the pounding locations cannot be predefined. To more realistically consider the arbitrary poundings between asymmetric structures, detailed three-dimensional (3D) finite element models (FEM) and arbitrary pounding algorithm are necessary. This paper carries out numerical simulations on the pounding responses between a symmetric rectangular-shaped building and an asymmetric L-shaped building by using the explicit finite element code LS-DYNA. The detailed 3D FEMs are developed and arbitrary 3D pounding locations between these two buildings under bi-directional earthquake ground motions are investigated. Special attention is paid to the relative locations of two adjacent buildings. The influences of the left-and-right, fore-and-aft relative locations and separation gap between the two buildings on the pounding responses are systematically investigated.

• Geomechanics and Engineering
• /
• v.35 no.6
• /
• pp.617-626
• /
• 2023

In this study, three-dimensional numerical parametric study was conducted to explore deformation mechanisms of grouped piled-raft-foundation due to lateral load in clays. Effects of load intensity, loading angle, soil stiffness, pile diameter, pile spacing and pile length on foundation deformations were explored. It is found that the smallest and largest movements of pile foundation are induced when the loading angles are 0° and 30°~60°, respectively. By increasing loading angle from 0° to 30°~60°, the resultant horizontal movements and settlements increase by up to 20.0% and 57.1%, respectively. Since connection beams can substantially increase integrity of four piled raft foundation, resultant horizontal movements, settlements and bending moments induced in the piled raft foundation decrease by up to 54.0%, 8.8% and 46.3%, respectively. By increasing soil stiffness five times, resultant horizontal movements and settlements of pile foundation decrease by up to 61.7% and 13.0%, respectively. It is indicated that effects of connection beam and soil stiffness on settlements of pile foundation are relatively small. When pile diameter is less than 1.4 m, deformations of piled raft foundation decrease substantially as a reduction in the pile diameter. Two dimensional groups are proposed to develop calculation charts of horizontal movements and settlements of pile foundation. The proposed calculation charts can directly estimate movements of piled raft foundation under arbitrary loading, ground and pile conditions.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.19 no.3
• /
• pp.355-373
• /
• 2017

Tunnelling in urban areas, it is essential to understand existing structure-tunnel interactive behavior. Serviced structures in the city are supported by pile foundation, since they are certainly effected due to tunnelling. In this research, thus, pile load distribution and ground behavior due to tunnelling below grouped pile were investigated using laboratory model test. Grouped pile foundations were considered as 2, 3 row pile and offsets (between pile tip and tunnel crown: 0.5D, 1.0D and 1.5D for generalization to tunnel diameter, D means tunnel diameter). Soil in the tank for laboratory model test was formed by loose sand (relative density: Dr = 30%) and strain gauges were attached to the pile inner shaft to estimate distribution of axial force. Also, settlements of grouped pile and adjacent ground surface depending on the offsets were measured by LVDT and dial gauge, respectively. Tunnelling-induced deformation of underground was measured by close range photogrammetric technique. Numerical analysis was conducted to analyze and compare with results from laboratory model test and close range photogrammetry. For expression of tunnel excavation, the concept of volume loss was applied in this study, it was 1.5%. As a result from this study, far offset, the smaller reduction of pile axial load and was appeared trend of settlement was similar among them. Particulary, ratio of pile load and settlement reduction were larger when the offset is from 0.5D to 1.0D than from 1.0D to 1.5D.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.6 no.4
• /
• pp.327-343
• /
• 2004

During tunnel construction, ground failures often occur due to existence of weak zones, such as faults, joints, and cavities, ahead of tunnel face. It is hard to detect effectively weak zones, which can lead underground structure to fail after excavation and before supporting, by using conventional characterization methods. In this study, an enhanced analytical method of predicting weak zones ahead of tunnel face is developed to overcome some problems in the conventional geophysical exploration methods. The analytical method is based on Coulomb's and Gauss' laws with considering the characteristics of electric fields subjected to rock mass. Using the developed method, closed form solutions are obtained to detect a spherical shaped zone and an oriented fault ahead of tunnel face respectively. The analytical results suggest that the presence of weak zones and their sizes, location, and states can be accurately predicted by combining a proper inversion process with resistance measured from several electrodes on the tunnel face. It appears that the skin depth or resistivity in rock mass is affected by the diameter of tunnel face, natural electric potential and noises induced by experimental measurement and spatial distribution of uncertain properties. The developed analytical solution is verified through experimental tests. About 1800 concrete blocks of 5cm by 5cm by 5cm in size are prepared and used to model a joint rock mass around tunnel face. Weak zones are simulated ahead of tunnel face with a material which has relatively higher conductivity than concrete blocks. Experimental results on the model test show a good agreement with analytical results.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.22 no.1
• /
• pp.23-46
• /
• 2020

In the current work, a series of three-dimensional finite element analyses have been carried out to understand the behaviour of pre-existing single piles to adjacent tunnelling by considering the tunnel face pressures and the relative location of pile tips with respect to the tunnel. The numerical modelling has analysed the effect of the face pressures on the pile behaviour. The analyses concentrate on the ground settlements, the pile head settlements, the axial pile forces and the shear stress transfer mechanism at the pile-soil interface. The head settlements of the pile (the vertical distance between the pile and the tunnel: 0.25D, where D is the tunnel diameter) directly above the tunnel crown with the face pressure 50% of the in-situ horizontal soil stress at the tunnel springline decreased by about 38% compared to corresponding settlements with a face pressure 25% of the in-situ horizontal soil stress at the tunnel springline. Furthermore, it was found that the smaller the face pressure, the larger the tunnelling-induced ground movements and the axial pile forces were and the higher the degree of the shear strength mobilisation at the pile-soil interface. When the piles were outside the tunnel influence zone, compressive pile forces were developed due to tunnelling. It has been found that the ground settlements and the pile settlements are heavily affected by the face pressures and the position of the pile tip relative to the tunnel. In addition, the computed results have been compared with relevant studies previously reported in literature. The behaviour of the piles has been extensively examined and analysed by considering the key features in great detail.