• Bulletin of the Korean Chemical Society
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• v.32 no.2
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• pp.595-598
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• 2011

Cetirizine hydrochloride reacted with $BiI_4^-$ in an acidic aqueous solution to form precipitate. After centrifugation, the atomic emission intensity of $Bi^{3+}$ contained in the supernatant solution was measured at the characteristic wavelength of 206.170 nm. The difference between the spectral signal intensity of the blank solution and that of the supernatant, ${\Delta}I$, was linearly related to the concentration of cetirizine hydrochloride. As a result, a new inductively coupled plasmaatomic emission spectrometric (ICP-AES) method was developed for the analysis of cetirizine hydrochloride. The linear range was from 27.7 to 184.8 $mg{\cdot}L^{-1}$, with a correlation coefficient (r) of 0.9961 and a detection limit of 9.6 $mg{\cdot}L^{-1}$. This method is simple and accurate, Without using toxic organic solvents, and is feasible for the quality control of cetirizine hydrochloride tablets and capsules.

• Analytical Science and Technology
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• v.10 no.4
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• pp.231-239
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• 1997

We developed a procedure that can effectively separate and determine tertiary amines and quaternary ammonium salts in some samples with reverse phase ion-pair high performance chromatography, employing indirect spectrophotometric detection method. Detection and ion-pairing reagents used in this study were benzyl trimethylammonium chloride (BTMACl) and sodium dodecyl sulfate(DDSANa), respectively. Eluting the electrolyte solutions of some commercial electrolytic capacitors with a MeOH(40):water(60) eluent (pH 8.5 adjusted with NH4Cl-NH3 buffer) containing 0.010M DDSANa and 0.004 M BTMACl through Supelco LC-18 or ${\mu}$-Bondapak phenyl column, amines and ammonium salts contained in the sample were successfully separated and determined. Varying the composition, especially the content of quaternary ammonium salts, of electrolyte solutions based on this analysis. we could prepare the low impedance(0.08~0.13) electrolytic capacitors with excellent electrical properties and it was a confirmation that the analysis is favorable.