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Relationship between Bronchial Sensitivity and Bronchial Reactivity in Asthma (기관지천식 환자에서 기관지 감수성과 기관지 반응성에 관한 연구)

  • Seo, Ki-Youl;Chang, Jung-Hyun;Cheon, Seon-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.2
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    • pp.341-350
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    • 1998
  • Background: Airway hyperreponsiveness is a cardinal feature of asthma. It consists of both an increased sensitivity of the airways, as indicated by a smaller concentration of a constrictor agonist needed to initiate the brochoconstrictor response and an increased reactivity, increments in response induced subsequent doses of constrictor, as manifested by slopes of the dose-response curve. The purpose of this study is to observe the relationship between bronchial sensitivity and reactivity in asthmatic subjects. Method: Inhalation dose-response curves using methacholine were plotted in 56 asthmatic subjects. They were divided into three groups(mild, moderate and severe) according to clinical severity of bronchial asthma. PC20 were determined from the dose-response curve as the provocative concentration of the agonist causing a 20% fall in FEVl. PC40 were presumed or determined from the dose response curve, using the PC20 and the one more dose after PC20. Reactivity was calculated from the dose-response curve regression line, connecting PC20 with PC40. Results: PC20 were 1.83mg/ml in mild group, 0.96mg/ml in moderate, and 0.34mg/ml in severe. PC40 were 7.l7mg/ml in mild group, 2.34mg/ml in moderate, and 0.75mg/ml in severe. Reactivity were $24.7{\pm}17.06$ in mild group, $46.1{\pm}22.l0$ in moderate, and $59.0{\pm}5.82$ in severe. There was significant negative correlation between PC20 and reactivity (r= -0.70, P<0.01). Conclusion: Accordingly, there was significant negative correlation between bronchial sensitivity and brochial reactivity in asthmatic subjects. However, in some cases, there were wide variations in terms of the reactivity among the subjects who have similar sensitivity. So both should be assessed when the bronchial response tor bronchoconstrictor agonists is measured.

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Short Culm, Lodging Tolerance, Non-glutinous Foxtail millet (Setaria italica Beauv.) Variety 'Daname' (단간 내도복 메조 '단아메')

  • Ko, Jee-Yeon;Song, Seok-Bo;Choe, Meyong-Eun;Kwak, Do-Yeon;Kim, Jung-In;Park, Chang-Hwan;Choi, Ji-Myeong;Woo, Koan-Sik;Jung, Tae-Wook
    • Korean Journal of Breeding Science
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    • v.49 no.4
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    • pp.396-402
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    • 2017
  • 'Daname' is a foxtail millet(Setaria italica Beauv.) variety developed and registered by Department of Southern Area Crop Science, NICS, RDA in 2014. This variety which collected from IT252182 was developed through pure line selection. 'Daname' is a early-maturing variety having 100 days of growth period from seeding to harvesting in Milyang of Korea. The culm length is about 97 cm which is 20cm shorter culm length than standard variety 'Hwanggeumjo', and it showed tolerant to lodging in field. The panicle shape is a cylindrical and the length is about 19cm. According to the grain, seed color and dehusked grain colors are orange and yellow and endosperm characteristic is non-glutinous. The yield performance of this variety was about $3.81t\;ha^{-1}$ in local adaptability test from 2013 to 2014 and it showed similar with standard variety 'Hwanggeumjo'. As the addition amount of 'Daname' in rice increased from 0% to 30% and 100%, the antioxidant ability of 'Daname' added rice and hardness/stickiness balances were increased. But we could not find out the difference of hardness/stickiness balances between 0%and 10% addition. So, 10% addition amount was concluded to increase antioxidant ability regardless eating quality of cooked rice. (Variety registration No. 6243)

Material Properties and Conservation of 『Collection of Yi Chungmugong』 in Manuscript (『이충무공전서』 정고본의 지질분석과 보존처리)

  • Lim, Se-Yeon;Ahn, Ji-Yoon;Yang, Min-Jeong
    • Korean Journal of Heritage: History & Science
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    • v.51 no.4
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    • pp.108-119
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    • 2018
  • "The Collection of Yi Chungmugong" manuscript is a hand-written manuscript of the volume 1 consisting of the Collection, published in 1795 and it seems to have completed the contents of the book by correcting the first part of the book before print. The book adopted a form of Seonjangbon(線裝本) of Ochimanjeongbeop(五針眼訂法) and was urgently needed some measures to preserve because it has been much damaged by stains, loss and oxidation due to moisture on the bottom of it. In addition, a scientific investigation was applied to find out the features of the quality of paper and fiber used for the book, which would be reflected in the process of the preservation. The characteristics of paper were measurmented for size(cm), thickness(mm), weight(g), basis weight($g/m^2$), density($g/cm^3$), chain line and laid lines($3{\times}3cm$). The measurement showed that the characteristics of paper used in royal books published in the late Joseon Dynasty. For the paper-fiber of the book, C stain was used and the technique revealed that the book is made of bast fibre of paper mulberry and its binding strings are cotton. SEM-EDS analysis was performed to verify the existence of additives in paper. As a result of the analysis, The crystallized calcium was detected in addition to the main components carbon(C) and oxygen(O). This artifact is the unique final version of "The collection of Yi Chungmugong", which has considerable value in terms of academic research, besides it helps to understand how to print books of Joseon Dynasty. And it also has a very accurate information of when and where the book was made, which primarily could be resources to conserve and restore for other book heritage.

Determination of Freely Dissolved PAHs in Seawater around the Korean Peninsula Using High Speed Rotation-Type Passive Sampling Device (고속회전식 수동형 채집 장치를 이용한 한반도 주변해역에서의 자유용존상 PAHs 측정)

  • JANG, YU LEE;LEE, HYO JIN;JEONG, HAEJIN;JEONG, DA YEONG;KIM, NA YEONG;KIM, GI BEUM
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.1
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    • pp.37-48
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    • 2021
  • A new high speed rotation type-passive sampling device (HSR-PSD), which can rotate seawater at high speed and absorb easily and quickly the freely dissolved hydrophobic organic contaminants from seawater, was developed and then applied around the Korean Peninsula. Freely dissolved concentrations (Cfree) of polycyclic aromatic hydrocarbons (PAHs) were determined using the HSR-PSD with low density polyethylene (LDPE) sheets as a passive sampler. Furthermore, dissolved concentrations (Cdissolved) of PAHs in seawater were also obtained from high volume water sampling as a conventional method to account for actual bioavailability. When the LDPE sheets were rotated in the HSR-PSD at 900 rpm, PAHs with log KOW 3.4 ~ 5.2 were equilibrated between the LDPE and water in 5 hours. Although the high molecular weight PAHs with log KOW 5.6 ~ 6.8 was expected to be 2 to 30 days to reach the equilibrium, the Cfree of the PAHs at equilibrium could be corrected using performance reference compounds in 5 hours. Meanwhile, the total Cfree of PAHs were from 0.32 to 1.2 ng/L, which were higher than reported values in other oceans, but lower than in coastal water such as estuary, harbor, or shore. A bioavailability from the detected PAHs was highest at the sampling line near the dumping site of the Yellow Sea. Predicted residual concentrations in biota were relatively higher in offshore including the dumping site than in coastal regions.

A Study on Distribution of Mössbauer Spectroscopy in Al Doped Garnet (Al을 치환한 Garnet의 Mössbauer분포 함수 연구)

  • Min, Byoung-Ki;Kim, Sam-Jin;Shim, In-Bo;Kim, Chul-Sung
    • Journal of the Korean Magnetics Society
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    • v.12 no.1
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    • pp.1-6
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    • 2002
  • Al$\^$3+/ substituted garnet Y$_3$Fe$\_$5-x/Al$\_$x/O$\_$12/ (x=0.0, 0.25, 0.5, 0.75, 1.0) was fabricated by sol-gel method. The crystallographic and magnetic properties of Y$_3$Fe$\_$5-x/Al$\_$x/O$\_$12/ have been studied with Mossbauer spectroscopy, x-ray diffraction (XRD), thermogravimetry analysis (TGA), differential thermal analysis (DTA), and vibrating samples magnetometer (VSM). The crystal structure of Y$_3$Fe$\_$5/O$\_$12/ is found to be a cubic with the lattice constant a$\_$0/= 12.381$\pm$0.005 $\AA$. The lattice constants a$\_$0/ decreases linearly from 12.381 to 12.304 A as the Al concentration (x) increases from x=0.0 to 1.0. Mossbauer spectra of measured at Y$_3$Fe$\_$5-x/A1$\_$x/O$\_$12/ various absorber temperatures of 13 to 600 K. Mossbauer spectrum for x = 0.0 is consist of well resolved two sets of six line patterns. While with increasing Al concentration outer sextet patters, which is originating from octahedral sites, broadens widely. These phenomena are interpreted in terms of random probability distributions of Fe$\^$3+/ and Al$\^$3+/ in tetrahedral site.

Solvent-Polymer Interactions for Stable Non-Aqueous Graphene Dispersions in the Presence of PVK-b-PVP Block Copolymer (PVK-b-PVP 블록 공중합체의 존재 하에서 안정한 비 수계 그래핀 분산액을 위한 용매-고분자 상호작용에 관한 연구)

  • Park, Kyung Tae;Perumal, Suguna;Lee, Hyang Moo;Kim, Young Hyun;Cheong, In Woo
    • Journal of Adhesion and Interface
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    • v.18 no.3
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    • pp.109-117
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    • 2017
  • Poly(N-vinyl carbazole) (PVK) homopolymer, poly(4-vinylpyridine) (PVP) homopolymer, and PVK-b-PVP block copolymer were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization and the polymers were used to prepare non-aqueous graphene dispersions with four different solvents, ethanol, N-methyl-2-pyrrolidone (NMP), dichloromethane (DCM), and tetrahydrofuran (THF). $^1H-$ and $^{13}C-NMR$ spectroscopy, size exclusion chromatography (SEC), and differential scanning calorimetry (DSC) were carried out to confirm the chemical structure of the polymers. Stability of graphene dispersions was measured by on-line turbidity measurement. Time-dependent Turbiscan Stability Index (TSI) values were interpreted in terms of surface tension (${\sigma}$) and solubility parameter (${\delta}$) among solvents, polymers, and graphene. It was confirmed that the solubilities of polymer and surface tension between solvent and graphene affected the dispersion stability of graphene. PVK-b-PVP block copolymer could effectively maintain the low TSI values of graphene dispersions in ethanol and THF, which have been known as poor solvents for graphene dispersions. It can also be noted that DCM shows good dispersion stability comparable to NMP, which has been known as the best solvent for graphene dispersion.

A Study on the Estimation of In-situ Undrained Shear Strength Using Effective Stress Paths of Reconstituted Sample by Unconfined Compression Test (재구성 시료의 일축압축시험에서 유효응력경로를 이용한 원지반의 비배수 전단강도 추정에 관한 연구)

  • 박성재;오원택;정경환;여주태
    • Journal of the Korean Geotechnical Society
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    • v.19 no.1
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    • pp.93-102
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    • 2003
  • Unconfined compression test (UC) has been widely used to determine the undrained shear strength ($c_u$) of clay, because it is convenient and economical. However, UC can not represent the behaviour of in-situ stress condition and the strength obtained by the test is generally underestimated compared to that of triaxial compression, due to no confining pressure. Therefore, a simple and practical method to correct the ($c_u$) for sample disturbance and to be used in geotechnical practice is needed. This study is aimed at proposing the method to estimate in-situ undrained shear strength from UC with suction measurement. The proposed method is based on theoretical shear strength equation of perfect sample (Noorany & Seed, 1965), and effective overburden stress and analysis results ($A_f,\phi'$) of effective stress behaviour by UC are needed for the equation. The shear resistance angle ($\phi'$) can be simply estimated through the result that $K_f$-line slope of the UC is 1.6 times higher than that of triaxial compression test. The result of this study shows that the measured strength by this method is very similar to that of the undrained shear strength by triaxial compression test (CK$_0$UC).

Miniaturization of GPS Microstrip Antenna for Small Drone (초소형 드론 탑재용 GPS 대역 마이크로스트립 안테나의 소형화)

  • Kim, Wan-Ki;Woo, Jong-Myung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.3
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    • pp.62-72
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    • 2022
  • In this study, a miniaturized GPS band(L1 : 1.575 GHz) antenna that can be mounted on a small drone is proposed. The miniaturization was designed by applying the perturbation method based on the λ/4 microstrip antenna and lengthening the current path at the edge of the patch. The miniaturized antenna was fabricatred such that it could be attached to the surface of styrofoam(εr=1.06, t=10 mm) having a size of 10 mm × 9 mm × 10 mm (0.05 λ × 0.05 λ × 0.05 λ). The thickness and length of the feeding line and the spacing between short stubs were adjusted for impedance matching. S11 was found to be -18.8 dB at the center frequency of the fabricated antenna, 1.575 GHz. The radiation pattern measurement results show that the maximum gain of Eθ is 1.87 dBi in 0 directions in the xz-plane, and that Eθ is an omnidirectional characteristic with an average gain of -1.7 dBi in the yz-plane. It was found that the antenna can be used as an ultra-small microstrip antenna, which can be mounted on a small dron for GPS, and is capable of preserving a reduction ratio of 98.8% as compared to a λ/2 microstrip patch antenna.

Reproducibility and reliability of head posture obtained by the outer canthus indicator (Outer Canthus Indicator를 이용한 두부 자세 기록법의 재현성)

  • Kim, Young-Jae;Sohn, Byong-Wha;Lee, Kee-Joon
    • The korean journal of orthodontics
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    • v.40 no.2
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    • pp.77-86
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    • 2010
  • Objective: The purposes of this study were to evaluate the reproducibility and reliability of head posture obtained by registering outer canthus as a soft tissue landmark with the Outer Canthus Indicator (OCI). Methods: Twenty-one adults with normal facial morphology were enrolled in this study (mean age $27.5\;{\pm}\;1.72$ years). To register initial head posture, height of the outer canthus from the ear rod plane was measured using OCI. Head posture was reproduced by moving the head upwards and downwards until the outer canthus was in a straight line with the indicator set at a registered height. After the head posture is reproduced by two operators after two days, lateral photographs were taken. Computerized photometric analyses of the photographs were performed. Results: The head rotations around the transverse axis were $0.69\;{\pm}\;0.43^{\circ}$, $0.98\;{\pm}\;0.65^{\circ}$ from each of the two operators. Standard errors were $0.09^{\circ}$ and $0.14^{\circ}$ each, which were similar to results from past research findings. There were no significant differences between the data from the two operators (p > 0.05). There were no correlations between the head rotation around the horizontal and vertical axes (p > 0.05). Conclusions: The present study suggests that OCI-registered head posture may minimize errors from vertical head rotation in cephalometry and photometry.

W-type hexaferrite-epoxy composites for wide-band radar absorption (광대역 레이다 흡수용 W-type 육방정 페라이트-에폭시 복합 소재)

  • Su-Mi Lee;Tae-Woo Lee;Young-Min Kang;Hyemin Kim
    • Journal of Aerospace System Engineering
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    • v.17 no.1
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    • pp.42-50
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    • 2023
  • In this study, hexagonal ferrite powder with chemical formula SrZn2-xCoxFe16O27 was synthesized by a solid-state reaction method and its electromagnetic (EM) wave absorption characteristics were evaluated in the frequency range of 0.1-18 GHz with absorber thickness range of 0 - 10 mm. Reflection loss (RL) affecting electromagnetic wave absorption performance was calculated based on the transmission line theory using measured complex permeabilities and permittivities. RL spectra were also directly measured for some samples. They were well matched with calculated results. High-frequency complex permeability characteristics were changed gradually according to the amount of Co substitution (x). The EM wave absorption frequency band could be tuned accordingly. Hexaferrite samples with x = 1.0, 1.25, and 1.5 exhibited remarkable maximum electromagnetic wave absorption performances with minimum RL (RLmin) lowered than -50 dB. They also showed a very broad frequency band (Δf > 10 GHz) in which more than 90% of the EM wave energy absorption occurred (RL ≤ -10 dB).