We propose a multi-state model to analyze semi-competing risks data with interval-censored or missing intermediate events. This model is an extension of the three states of the illness-death model: healthy, disease, and dead. The 'diseased' state can be considered as the intermediate event. Two more states are added into the illness-death model to incorporate the missing events, which are caused by a loss of follow-up before the end of a study. One of them is a state of the lost-to-follow-up (LTF), and the other is an unobservable state that represents an intermediate event experienced after the occurrence of LTF. Given covariates, we employ the Lin and Ying additive hazards model with log-normal frailty and construct a conditional likelihood to estimate transition intensities between states in the multi-state model. A marginalization of the full likelihood is completed using adaptive importance sampling, and the optimal solution of the regression parameters is achieved through an iterative quasi-Newton algorithm. Simulation studies are performed to investigate the finite-sample performance of the proposed estimation method in terms of empirical coverage probability of true regression parameters. Our proposed method is also illustrated with a dataset adapted from Helmer et al. (2001).
This study presents a probabilistic distributed hydrological model for Ephemeral catchment, where zero flow often occurs due to the influence of distinct climate characteristics in South Korea. The gridded hydrological model is developed by combining the Sacramento Soil Moisture Accounting Model (SAC-SMA) runoff model with a routing model. In addition, an error model is employed to represent a probabilistic hydrologic model. To be specific, the hydrologic model is coupled with a censoring error model to properly represent the features of ephemeral catchments. The performance of the censoring error model is evaluated by comparing it with the Gaussian error model, which has been utilized in a probabilistic model. We first address the necessity to consider ephemeral catchments through a review of the extensive research conducted over the recent decade. Then, the Yongdam Dam catchment is selected for our study area to confirm the usefulness of the hydrologic model developed in this study. Our results indicate that the use of the censored error model provides more reliable results, although the two models considered in this study perform reliable results. In addition, the Gaussian model delivers many negative flow values, suggesting that it occasionally offers unrealistic estimations in hydrologic modeling. In an in-depth analysis, we find that the efficiency of the censored error model may increase as the frequency of zero flow increases. Finally, we discuss the importance of utilizing the censored error model when the hydrologic model is applied for ephemeral catchments in South Korea.
This study aims to be of help to cope with internal and external circumstances of hospital effectively by analyzing the weight of role for a hospital manager which has been changing. It surveyed 191 top managers and administrators working in a medical institute like hospital located in Busan, Ulsan and Kyungnam area from 20 November, 2007 to 29 February, 2008. The results of this study were as follows: The top manager thought that the role as a leader is the most important role as a manager in present, but the role as an enterpriser is also very important in future, however, they had troubles in the role of a representative which they have carried out in present. In order to overcome the current medical situation that competition is getting keen, it seemed that they expected the role as an enterpriser would be more important in future for competition and organization improvement. The administrator thought the role as a leader is the most important in present, in future and in current performance. It was considered that they recognized the importance of team work, order, goal of the organization, strategies, and information interchange regarding the characteristics of hospital that there are people of various kinds of occupations.
Journal of Korean Society of Industrial and Systems Engineering
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v.41
no.3
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pp.72-82
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2018
In this paper, we identify risk factors that are likely to occur during the lifecycle of a new product development (NPD) project from the literatures, and identify the three objectives or three constraints that will ultimately be achieved for project success in the ICT industry : performance (scope/quality), schedule (time), and cost. Firstly, we interviewed the project experts to classify the risk factors according that the final project objectives are changeable based on scope/quality, time and cost budget constraints. Secondly, the survey for pairwise comparisons between the risk factors was asked to the project managers and members who had ever actually participated in the NPD projects of ICT industry to determine the priority ranks on relative importance using AHP (Analytic Hierarchy Process). The risk factors negatively affecting the goals of projects were analyzed by using the AHP respectively in four project stages during the life cycle of the project. The comparison of risk factors within each stage is a different approach unlike the literatures which have covered project's overall risk assessment. There is an advantage that risk management can be effectively performed with priorities according to each stage from the start to the end of the project. In other words, it is necessary to identify what risk factors will occur in each stage, and to have ideas at each stage with the priorities so that they can be mitigated and eliminated before actual occurrence. As a result, risks on scope & quality changes were found to be the most important considerations for initiative stage of NPD projects in the ICT industry, whereas in the final stage, risks on schedule (time) changes were the most important priorities. Among the ICT industry product categories, 'communication and broadcasting devices' and 'IT and communication based devices' generally have a high priority in terms of risks on scope & quality changes when initiating the project. At the closing stage of the project, however, considering that schedule (time) changeable risk is getting higher, these products tend to target at B2B market rather than B2C because the new products must be delivered and launched in time as customer firm required.
In modern economic societies, individuals are governed by organizations and they managed their daily lives in one way or another. through such organizations. All activities of the organizations are carried out by the job performance of individuals. Job is a very important factor for both individuals and organizations. The study is the explore. the effect of job characteristics and organizational characteristics on the job satisfaction in the small- and medium- sized firms in Namdong und Banwool Area. Job characteristics and organizational justice were hypothesized to be positively related to job satisfaction. To examine the influence of job characteristics and organizational justice on job satisfactions, data were collected from 320 employees of the small- and medium- sized manufacturing companies in Namdong und Banwool Area. This research took independent variables as the core job characteristics of the job characteristic theory such as skill variety, job stagnation, job importance, autonomy, feed back, and organizational justice as distributive and procedural justice. As a result, I can make the following suggestions. First, The Results show that job characteristics and organizational justice were significant and important predictors of job satisfaction. Secondarily, to raise the job desire of organizational members, job must be designed in such a way that the members can highly recognize their job characteristics.
Journal of the Institute of Electronics Engineers of Korea SP
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v.44
no.6
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pp.100-110
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2007
When compressed video data is transmitted over error-prone network such as wireless channel, data is likely to be lost, so the quality of reconstructed picture is severely decreased. It is specially so in case that important information such as motion vector or macroblock mode is lost. H.264/AVC standard includes DP as error resilient technique for protecting important information from error in which data is labeled according to its relative importance. But DP technique requires a network that supports different reliabilities of transmitted data. In general, the benefits of UEP is sought by sending multiple times of same packets corresponding to important information. In this paper, we propose MDC technique based on data partitioning technique. The proposed method encodes motion vector of H.264/AVC standard into multiple parts using MDC and transmits each part as independent packet. Even if partial packet is lost, the proposed scheme can decode the compressed bitstream by using estimated motion vector with partial packets correctly transmitted, so that achieving improved performance of error concealment with minimal effect of channel error. Also in decoding process, the proposed multiple description matching increases the accuracy of estimated lost motion vector and quality of reconstructed video.
Kim, Myung-Jin;Lee, Ju-Youn;Kim, Sung-Jo;Choi, Jeom-Il
Journal of Periodontal and Implant Science
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v.38
no.1
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pp.97-102
/
2008
Purpose: Periodontal intrabony defects have great deal of importance since they contribute to the development of periodontal disease. Current treatment regimens for intrabony defects involve grafting of numerous bony materials, GTR using biocompatible barriers, and biomodification of root surface that will encourage the attachment of connective tissue. Xenograft using deproteinized bovine bone particles seems to be very convenient to adjust because it doesn't require any donor sites or imply the danger of cross infections. These particles are similar to human cancellous bone in structure and turned out to be effective in bone regeneration in vivo. We here represent the effectiveness of grafting deproteinized bovine bone particles in intrabony defect and furcation involvements that have various numbers of bony walls. Materials and methods: Open flap debridement was done to remove all root accretions and granulation tissue from the defects within persisting intrabony lesions demonstrating attachment loss of over 6mm even 3 months after nonsurgical periodontal therapy have been completed. Deproteinized bovine bone particles($BBP^{(R)}$, Oscotec, Seoul) was grafted in intrabony defects to encourage bone regeneration. Patients were instructed of mouthrinses with chlorohexidine-digluconate twice a day and to take antibiotics 2-3 times a day for 2 weeks. They were check-up regularly for oral hygiene performance and further development of disease. Probing depth, level of attachment and mobility were measured at baseline and 6 months after the surgery. The radiographic evidence of bone regenerations were also monitored at least for 6 months. Conclusion: In most cases, radio-opacities increased after 6 months. 2- and 3-wall defects showed greater improvements in pocket depth reduction when compared to 1-wall defects. Class I & II furcation involvements in mandibular molars demonstrated the similar results with acceptable pocket depth both horizontally and vertically comparable to other intrabony defects. Exact amount of bone gain could not be measured as the re-entry procedure has not been available. With in the limited data based on our clinical parameter to measure pocket depth reduction following $BBP^{(R)}$ grafts, it was comparable to the results observed following other regeneration techniques such as GTR.
The Journal of Korean Academy of Sensory Integration
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v.15
no.2
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pp.1-21
/
2017
Objective : The aims of the this study is to identify job characteristics, to generate job description, and additionally to investigate duty task of the job for Korean pediatric occupational therapist focused on sensory integration intervention. Methods : In the first stage, job analysis of pediatric occupational therapist focused on sensory integration intervention was performed by an advisory committee consist of the DACUM panel. Through the job analysis, job description with definition was established. In the second stage, a survey was performed for 141 pediatric occupational therapist using a questionnaire based on the job description in order to investigate importance, frequency and difficulty of duty task and task elements of the job. This process was done from May to September 2017. Results : The job definition drew from this study was 'Pediatric occupational therapist provides occupational therapy services to children and adolescents to support occupational performance and social participation including daily activities and play". Through the job description established in this study, 9 duties (consulting, evaluation, intervention plan, intervention, document, education, self-development, management, and administration), 28 tasks and 169 task elements were drew. In the survey, among the duty tasks and task elements, 'ensure physical safety' and 'perform a session' were selected as the most important task, and 'ensure safety of children, sensory integrative equipment and environment' and 'prepare a safe environment' were selected as the most important element. Conclusion : This study defined job demands and characteristics of pediatric occupational therapist who performs sensory integration intervention. It is expected that this study can be used a resource to develop and/or improve educational program related.
Objectives: The purpose of this study was to investigate whether longitudinal changes in positive and negative symptoms affect cognitive functioning in chronic schizophrenia. Methods: Sixty-eight patients diagnosed with DSM-IV schizophrenia were examined on two occasions over 6 months for symptoms and cognitive changes. Symptoms were measured by PANSS. Cognitive functions were examined for sustained attention, executive function, concentration and attention, and verbal memory and learning using Degraded Stimulus Continuous Performance Test, Wisconsin Card Sorting Test, Digit Span, and Rey Auditory Verbal Learning Test, respectively. Twenty control subjects were assessed to compare the cognitive scores of remitted schizophrenic patients. Results: Patients showed significant improvement in symptoms and all cognitive tests after 6 months treatments. Significant improvements in positive and negative symptoms did not predict improvements in any aspect of cognitive functioning measured. Normal controls performed significantly better than remitted schizophrenic patients on all cognitive tests. The results show no relationship between change in symptoms and change in cognition in chronic schizophrenia. Conclusion: We suggest that symptomatic and cognitive impairment may be a distinct construct. These findings highlight the importance of treating cognitive impairment in addition to the clinical symptoms of schizophrenia.
The Journal of Korean Institute of Communications and Information Sciences
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v.39C
no.1
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pp.17-27
/
2014
As the importance of Cooperative Engagement Capability and network-centric warfare has been dramatically increasing, it is necessary to develop distributed tracking systems. Under the development of distributed tracking systems, it requires tracking filters and data fusion theory for nonlinear systems. Therefore, in this paper, the problem of nonlinear track fusion, which is suitable for distributed networks, is formulated, four algorithms to solve the problem of nonlinear track fusion are introduced, and performance of introduced algorithms are analyzed. It is a main problem of nonlinear track fusion that cross-covarinaces among multiple platforms are unknown. Thus, in order to solve the problem, two techniques are introduced; a simplification technique and a approximation technique. The simplification technique that help to ignore cross-covariances includes two algorithms, i.e. the sample mean algorithm and the Millman formula algorithm, and the approximation technique to obtain approximated cross-covariances utilizes two approaches, by using analytical linearization and statistical linearization based on the sigma point approach. In simulations, BCS fusion is the most efficient scheme because it reduces RMSE by approximating cross-covariances with low complexity.
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