• Title/Summary/Keyword: imperfect

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Identification of Caenorhabditis elegans MicroRNA Targets Using a Kernel Method

  • Lee, Wha-Jin;Nam, Jin-Wu;Kim, Sung-Kyu;Zhang, Byoung-Tak
    • Genomics & Informatics
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    • v.3 no.1
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    • pp.15-23
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    • 2005
  • Background MicroRNAs (miRNAs) are a class of noncoding RNAs found in various organisms such as plants and mammals. However, most of the mRNAs regulated by miRNAs are unknown. Furthermore, miRNA targets in genomes cannot be identified by standard sequence comparison since their complementarity to the target sequence is imperfect in general. In this paper, we propose a kernel-based method for the efficient prediction of miRNA targets. To help in distinguishing the false positives from potentially valid targets, we elucidate the features common in experimentally confirmed targets. Results The performance of our prediction method was evaluated by five-fold cross-validation. Our method showed 0.64 and 0.98 in sensitivity and in specificity, respectively. Also, the proposed method reduced the number of false positives by half compared with TargetScan. We investigated the effect of feature sets on the classification of miRNA targets. Finally, we predicted miRNA targets for several miRNAs in the Caenorhabditis elegans (C. elegans) 3' untranslated region (3' UTR) database. Condusions The targets predicted by the suggested method will help in validating more miRNA targets and ultimately in revealing the role of small RNAs in the regulation of genomes. Our algorithm for miRNA target site detection will be able to be improved by additional experimental­knowledge. Also, the increase of the number of confirmed targets is expected to reveal general structural features that can be used to improve their detection.

Effect of the Llog normal-Nakagami Faded Interferers on Imperfect power-controlled DS/CDMA cellular system (CDMA 이동통신망을 이용한 무선측위 시스템)

  • 김정태;서덕영
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.8A
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    • pp.1163-1168
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    • 1999
  • This paper proposes a wireless positioning method using the CDMA mobile communicaton network. The proposed method is time-based positioning method that uses mobile-station arrival time of forward link signal from base-stations. In this mehtod there are TDOA and TOA methods that use time-difference-of-arrival and time-of-arrival, respectively. Error characteristics and implementation simplicity of the two methods are compared and analyzed each other. As a results, it showed that TDOA has advantage of less sensitivity to the time error compared to TOA but has disadantage of more sensitivity to the spatial error. Also, from architecture of the CDMA system that is time synchronized to only active base-station it is analyzed that adoption of TDOA method is more advantageous than TOA because time difference of signal arrival from the neighbor base-stations against the active base-station can be measured more easily. Therefore, conclusion is made that TDOA is beat suit to the time-based positioning method for the present CDMA mobile communication networkgorithm performs block-by-block coherent decoding with the aid of pilot symbols. It is shown that the complexity of the algorithm grows linearly as a function of sequence length. The performance of the algorithm is shown to better than that of the conventional pilot symbol aided (PSI) algorithm. Simulation results are presented to assess the performance of the algorithm and the results are compared with that of the conventional PSI alforithm.

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An Adaptive K-best Algorithm Based on Path Metric Comparison for MIMO Systems (MIMO System을 위한 Path Metric 비교 기반 적응형 K-best 알고리즘)

  • Kim, Bong-Seok;Choi, Kwon-Hue
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.11A
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    • pp.1197-1205
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    • 2007
  • An adaptive K-best detection scheme is proposed for MIMO systems. The proposed scheme changes the number of survivor paths, K based on the degree of the reliability of Zero-Forcing (ZF) estimates at each K-best step. The critical drawback of the fixed K-best detection is that the correct path's metric may be temporarily larger than K minimum paths metrics due to imperfect interference cancellation by the incorrect ZF estimates. Based on the observation that there are insignificant differences among path metrics (ML distances) when the ZF estimates are incorrect, we use the ratio of the minimum ML distance to the second minimum as a reliability indicator for the ZF estimates. So, we adaptively select the value of K according to the ML distance ratio. It is shown that the proposed scheme achieves the significant improvement over the conventional fixed K-best scheme. The proposed scheme effectively achieves the performance of large K-best system while maintaining the overall average computation complexity much smaller than that of large K system.

Interference Aware Receiver Filtering for Wireless Ad Hoc Networks (무선 애드혹 네트워크에서의 간섭 제어 수신 기법)

  • Shin, Sungpil;Lee, Byungju;Park, Sunho;Shim, Byonghyo
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.3
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    • pp.9-15
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    • 2013
  • Recent works on ad hoc network study have shown that achievable throughput can be made to scale linearly with the number of receive antennas even if the transmitter has only a single antenna. In this paper, we propose a non-parametric linear minimum mean square error (MMSE) receiver for achieving further gain in performance when the channel state information at receiver (CSIR) of interferers is imperfect. The key feature to make our approach effective is to exploit the autocorrelation of the received signal. In fact, by incorporating the desired channel information on top of the observations including interference and noise only, the proposed method achieves large fraction of the optimal MMSE transmission capacity without transmission rate loss. From the SINR analysis as well as transmission capacity simulations in realistic ad hoc network system, we show that the proposed non-parametric linear MMSE receiver brings substantial performance gain over existing multiple receive antenna algorithms.

Full mouth rehabilitation of the intellectually disabled patient with collapsed bite using partial removable dental prosthesis: a case report (교합이 붕괴된 지적장애 환자의 국소의치 수복증례)

  • Kim, Min-Ji;Yang, Hong-So;Park, Sang-Won;Lim, Hyun-Pil;Yun, Kwi-dug;Park, Chan
    • Journal of Dental Rehabilitation and Applied Science
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    • v.33 no.3
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    • pp.216-222
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    • 2017
  • Intellectual disability is an imperfect disorder in which mental development is permanently retarded and development of intellectual ability is inadequate. Having intellectual disabilities makes it difficult to handle their own work and adapt to social life. For this reason, it is difficult to hygienically manage the patient's oral condition, multiple caries are easily observed, and the periodontal disease incidence rate is high. The patient in this case is a 33-year-old female with a mental retardation first grade who had a problem with meals. In first visit, Patients had decreased occlusal vertical dimension and posterior bite collapse due to periodontitis and multiple caries. This case reports a satisfactory functional and esthetic results by reconstructing occlusion using partial removable dental prosthesis.

A Semantics-based Video Retrieval System using Annotation and Feature (주석 및 특징을 이용한 의미기반 비디오 검색 시스템)

  • 이종희
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.41 no.4
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    • pp.95-102
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    • 2004
  • In order to process video data effectively, it is required that the content information of video data is loaded in database and semantic-based retrieval method can be available for various query of users. Currently existent contents-based video retrieval systems search by single method such as annotation-based or feature-based retrieval, and show low search efficiency md requires many efforts of system administrator or annotator because of imperfect automatic processing. In this paper, we propose semantics-based video retrieval system which support semantic retrieval of various users by feature-based retrieval and annotation-based retrieval of massive video data. By user's fundamental query and selection of image for key frame that extracted from query, the agent gives the detail shape for annotation of extracted key frame. Also, key frame selected by user become query image and searches the most similar key frame through feature based retrieval method and optimized comparison area extracting that propose. Therefore, we propose the system that can heighten retrieval efficiency of video data through semantics-based retrieval.

Refining massive event logs to evaluate performance measures of the container terminal (컨테이너 터미널 성능평가를 위한 대용량 이벤트 로그 정제 방안 연구)

  • Park, Eun-Jung;Bae, Hyerim
    • The Journal of Bigdata
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    • v.4 no.1
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    • pp.11-27
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    • 2019
  • There is gradually being a decrease in earnings rate of the container terminals because of worsened business environment. To enhance global competitiveness of terminal, operators of the container terminal have been attempting to deal with problems of operations through analyzing overall the terminal operations. For improving operations of the container terminal, the operators try to efforts about analyzing and utilizing data from the database which collects and stores data generated during terminal operation in real time. In this paper, we have analyzed the characteristics of operating processes and defined the event log data to generate container processes and CKO processes using stored data in TOS (terminal operating system). And we have explained how imperfect event logs creating non-normal processes are refined effectively by analyzing the container and CKO processes. We also have proposed the framework to refine the event logs easily and fast. To validate the proposed framework we have implemented it using python2.7 and tested it using the data collected from real container terminal as input data. In consequence we could have verified that the non-normal processes in the terminal operations are greatly improved.

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Oral rehabilitation of a young adult with amelogenesis imperfect using metal-ceramic restoration: a clinical report (금속 도재 수복물을 이용한 청년기 법랑질 이형성증 환자의 수복증례)

  • Kim, Hong-Jun;Lee, Jae-Hoon;Han, Dong-Hoo;Moon, Hong-Suk
    • The Journal of Korean Academy of Prosthodontics
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    • v.50 no.3
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    • pp.210-215
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    • 2012
  • Some patients with generalized attrition and teeth discoloration may want their anterior teeth to be treated just for esthetic improvement. Ameologenesis imperfecta, however, should be considered for such patients prior to any treatment with thorough clinical and radiographic examination. If a patient is diagnosed with amelogenesis imperfecta, the treatment on anterior teeth just for esthetic purpose is not advisable. In this case, a young man with amelogenesis imperfecta was treated with metal-ceramic restorations. The patient had generalized attrition, teeth discoloration, crown fracture, and cross-bite on the left teeth. The ultimate objective of this treatment was to enhance esthetics and masticatory function. The cross-bite on the left anterior teeth was treated with restorations, whereas the reverse horizontal overlap was maintained on the posterior. The patient was satisfied with the result esthetically and functionally, and the third month recall examination revealed no pathologic changes associated with the treatment.

A Study on the Understanding and Errors of the Logarithmic Function in High School Students (고등학교 학생들의 로그함수에 대한 이해도 및 오류에 관한 연구)

  • 이경숙;김승동
    • Journal of the Korean School Mathematics Society
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    • v.5 no.1
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    • pp.111-122
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    • 2002
  • The purpose of this study was to examine high school second graders' understanding of the basic nature of logarithm, the major type of error they made about logarithmic function and the cause of such an error, and to seek ways to instruct it better. For that purpose, three research questions were posed: 1. Investigate how much high school students in their second year comprehend the nature of logarithm. 2. Analyze what type of error they make about logarithmic function. 3. Analyze the cause of their error according to the selected error models and how it could be taught more efficiently. The findings of this study were as below: First, the natural science students had a better understanding of the basic nature of logarithm than the academic students. What produced the widest gap between the two groups' understanding was applying the nature of logarithm to the given problems, and what caused the smallest gap was the definition of logarithm and the condition of base. Second, the academic students had a poorer understanding of the basic nature of logarithmic function graph and of applying the nature of logarithm to the given problems. Third, the natural science students didn't comprehend well the basic nature of logarithmic function graph, the nature of characteristics and mantissa. Fourth, for all the students from academic and natural science courses, the most common errors were caused by the poor understanding of theorem or nature of the [E4] model. Fifth, the academic students made more frequent errors due to the unfamiliar signs of the [El] model, the imperfect understanding of theorem or nature of the [E4] model, and the technical part of the [E6] model. Sixth, the natural science students made more frequent errors because of the improper problem interpretation of the [E2] model and the logically improper inference of the [E3] model.

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Quasi-Economic Integration in the Broiler Industry (브로일러산업의 유사경제통합)

  • 박영인
    • Korean Journal of Poultry Science
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    • v.11 no.1
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    • pp.33-39
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    • 1984
  • The pattern of economic integration in the broiler industry can be grouped into three categories; 1) non-integration, 2) quasi-integration and 3) complete-integration. It is general to see that the non-integration is quite common under the market conditions of perfect competition, whereas the complete integration is more preferable in the imperfect competition. The quasi-integration, however, exists at all phases where the complete integration is not fully formed and implemented, but the non-integration has begun to alter its nature into integrated structure. The broiler industry in Korea has been characterized with the typically non-integrated independent operation, resulting in considerable price fluctuation and unstable industry as a whole. As a means of solving out the problem stemed from the non-integrated, growers and agribusinessmen involved in broiler industry have tended to develope the regular customer relationship prevailed between two parties. In fact, it has been practiced for years that most growers have been dealt with factor suppliers or processors on a regular basis for advantages of better price and quality, useful information, management help and so forth. Under the customary transaction, no formal contract has been made due to simple buyers and sellers relations, not like the one used to be performed in the form of contractual agreement. The broiler industry realizes the direction to go ahead toward the formal arrangement of integrated system from current regular transactions. As more Vowers, suppliers and processors recognize the necessity of it, the non-integrated industry appears to become the partially integrated by developing the existing customer relationship in such a way that functions of integrators are. further expanded and better organized. As a result, a type of quasi-integration started to show up by an integrator dominated in the field of hatching, feedmilling, dressing and by a grower's coop, It is concluded, therefore, that the evolution of quasi-integration in Korea's broiler industry is continuously taking place, implying the close approach to the completely integrated broiler production and marketing system.

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