• Proceedings of the Ginseng society Conference
• /
• 2002.10a
• /
• pp.351-365
• /
• 2002

Earlier studies have demonstrated that chromium (Cr) VI compounds have been shown to be more toxic and carcinogenic than other chromium compounds. The aim of the present work was to evaluate the antioxidant effects of red ginseng against chromium VI -induced toxicity and free radical generation. Sixty adult male rats were divided into six equal groups include: control group, group received Cr VI alone (50 mg/kg b.w.), group treated with Korean ginseng (K. ginseng) alone (20 mg/kg b.w), group treated with Cr VI for 15 days then received K. ginseng for other 15 days, group treated with Cr VI and K. ginseng at the same time for 15 days, and group treated with K. ginseng for 15 days then Cr VI for other 15 days. The results revealed that Cr VI caused significant increase in ALT, AST, ALP, G-GT, urea, creatinine, and acid phosphatase. Whereas, it caused significant decrease in TP, albumin, testosterone, GPX, and SOD indicating a stress for liver, kidney and testes. K. ginseng alone caused significant increase in GPX and SOD activities in healthy animals and this result suggests a prophylactic role for this herb in protection against the damaging impact induced by free radical species. Furthermore, the other biochemical parameters measured after K. ginseng administration were comparable to the control values. Treatment with Cr VI followed by K. ginseng, Cr VI and K. ginseng or K. ginseng followed by Cr VI resulted in significant improvement in all tested parameters towards the normal values of the controls. However, this improvement was pronounced in the group pre-treated with K. ginseng for 15 days before Cr VI administration. It could be concluded that K. ginseng exhibited a protective action against the toxic effects of Cr VI and it had the ability to scavenge free radicals resulted from Cr VI intoxication.

• Safety and Health at Work
• /
• v.12 no.4
• /
• pp.479-489
• /
• 2021

Background: During 2011, a study was undertaken to assess safety conditions in Serbian underground coalmines by analysis of injury data. The study covered all Serbian coalmines, identified week spots from the aspect of safety, and recommended possible courses of action. Since then, Serbia has made changes to safety and health legislation; all coalmines introduced new preventive measures, adopted international standards, and made procedures for risk management. After 10 years a new study has been performed to analyze the impact of these changes. Materials and methods: In this study, the injuries that have occurred in the Serbian underground coal mines over the last 20 years were analyzed. Statistical data analysis was performed by IBM SPSS Statistics v23. The injuries that occurred in the last ten years were compared with the results of the previous study (2000-2009). The average values of injury rates for both periods were compared for each of the categories (severity, age, body part, qualification), and the results were presented as absolute difference or percentile difference. Results: The results showed reduction in the number of injuries in the category of 20-30 years old workers, where the new training procedures for workers, which were set by mandatory legal regulations, certainly contributed. They also showed an increase in the number of injuries in the category of old workers, which indicates that the law did not have a positive effect on this category. Conclusion: The total number of injuries is still high; therefore, it is necessary to introduce mechanization and automation in mines and have a better policy for older workers who retire later nowadays.

• The Korean Journal of Physiology and Pharmacology
• /
• v.23 no.1
• /
• pp.47-54
• /
• 2019

Estrogen withdrawal in post-menopausal women leads to overactivation of osteoclasts, which contributes to the development of osteoporosis. Inflammatory cytokines are known as one of mechanisms of osteoclast activation after estrogen deficiency. SPA0355 is a thiourea derivative that has been investigated for its antioxidant and anti-inflammatory activities. However, its efficacy in bone resorption has not been previously investigated. The aim of this study was to investigate the impact of SPA0355 on the development of osteoporosis and to explore its mode of action. In vitro experiments showed that SPA0355 inhibited receptor activator of $NF-{\kappa}B$ ligand (RANKL)-induced osteoclastogenesis in primary bone marrow-derived macrophages. This effect appears to be independent of estrogen receptor activation as ICI 180,782 failed to abrogate its effects on osteoclasts. Further signaling studies revealed that SPA0355 suppressed activation of the MAPKs, Akt, and $NF-{\kappa}B$ pathways. SPA0355 also increased osteoblastic differentiation, as evidenced by its effects on alkaline phosphatase activity and mineralization nodule formation. Intraperitoneal administration of SPA0355 to ovariectomized mice prevented bone loss, as verified by three-dimensional images and bone morphometric parameters derived from ${\mu}CT$ analysis. Noticeably, SPA0355 did not show hepatotoxicity and nephrotoxicity and also had little effect on hematological parameters. Taken together, the results indicate that SPA0355 may protect against bone loss in ovariectomized mice by stimulation of osteoblast differentiation and by inhibition of osteoclast resorption. Therefore, SPA0355 is a safe and potential candidate for management of postmenopausal osteoporosis.

• Journal of Convergence for Information Technology
• /
• v.8 no.6
• /
• pp.389-397
• /
• 2018

Recently, Global Shale gas development has expanded, increasing shale gas production has transformed the energy market.As a result of the reduction of energy facilities, in order to overcome the management deterioration of domestic casting valve industry and enter the enlarged shale gas plant, tried to confirm the SWOT factor through the second questionnaire based on the questionnaire survey of related industry experts and previous studies. As a strength-strategy, presented three factors besides collaboration with domestic companies, suggested four factors including product development specialized in shale gas plant as a weakness complement. Thesis offer to scholarly-Practical implications, Internal-external environmental factors, strategization for entering New energy market. thesis offer to scholarly, Practical implications, environmental factors, strategization for entering New energy market. After, analyze a important of research strategy, would like to study the impact on the company according to the ranking of importance.

• The Korean Journal of Air & Space Law and Policy
• /
• v.33 no.2
• /
• pp.199-224
• /
• 2018

Aviation's safety record continues to improve yearly, especially with respect to passenger and crew injuries and deaths. However, although the number of accidents has decreased over the decades, there are still many events, such as landings short of the runway and runway excursions, both of which pose threats to passenger and crew safety. Surviving any kind of aviation accident depends on the physiological threat and stress of the impact(s), the extent to which the physical structure surrounding the passengers and crew remains intact, and the ability of the passengers and crew to be able to escape the wreckage. The one action that both passengers and crew can carry out to help decrease the likelihood of crash-related injury or death is to assume an emergency brace position. Doing so has been demonstrated over several decades to improve survivability. While cabin crew are taught (and then might have to teach passengers in an emergency about the emergency brace position), passengers in many parts of the world never learn about the brace position unless they are involved in an emergency in which there is time to prepare for the landing. This lack of provision of information is related to the fact that most airlines do not provide information in the preflight safety briefing and some do not even provide the information in the passenger safety cards. Many countries do not require their airlines to do so, a fact, which in turn, is related to the lack of mention of the brace position in ICAO's Annex 6. Until standards and recommended practices are changed at the highest world level, passengers will continue to be deprived of this vital, life-saving information that they can use, potentially to help save their own lives.

• The Journal of Fisheries Business Administration
• /
• v.49 no.3
• /
• pp.67-83
• /
• 2018

This study is aimed at finding policy directions for Korean fisheries and fishing villages by using Delphi method for fisheries experts. Fisheries experts have highly evaluated the achievements of fostering aquaculture industry, seafood export support measures, and natural disasters relief and recovery arrangements among the policies promoted as so far. And it was recognized that policies such as fishery resources management, creation and recovery of fishery resources, improvement hygiene and seafood safety, and provision young fishermen with training and capacity building will be important. Future megatrends, for example changes in food consumption pattern, climate change, and demographic structure changes are expected to have a significant impact on fisheries and fishing villages. The Delphi survey indicates that the most important policy objective is to secure a stable fisheries production. In other words, fisheries policy in the future should be aimed at suppling sustainable seafood for popular consumption. Finding strategies and action plans that can achieve this goal will be an important policy issue. In conclusion, it is necessary that a number of fundamental researches carry out in Korea, which can lead to finding out a multifunctionality of fisheries and fishing village. In addition, it is important to expand the scope of fisheries policy, which can consider not only the fisheries producers but also seafood consumer's and young fishermen perspectives. Furthermore, it recommends that fishery policy needs to include fishery related industry as well as application of 4th industrial revolution technology to fishery.

• Structural Engineering and Mechanics
• /
• v.70 no.4
• /
• pp.479-497
• /
• 2019

In the current code design, the use of a uniform internal pressure coefficient of cooling towers as internal suction cannot reflect the 3D characteristics of flow field inside the tower body with different ventilation rate of shutters. Moreover, extreme weather such as heavy rain also has a direct impact on aerodynamic force on the internal surface and changes the turbulence effect of pulsating wind. In this study, the world's tallest cooling tower under construction, which stands 210m, is taken as the research object. The algorithm for two-way coupling between wind and rain is adopted. Simulation of wind field and raindrops is performed iteratively using continuous phase and discrete phase models, respectively, under the general principles of computational fluid dynamics (CFD). Firstly, the rule of influence of 9 combinations of wind speed and rainfall intensity on the volume of wind-driven rain, additional action force of raindrops and equivalent internal pressure coefficient of the tower body is analyzed. The combination of wind velocity and rainfall intensity that is most unfavorable to the cooling tower in terms of distribution of internal pressure coefficient is identified. On this basis, the wind/rain loads, distribution of aerodynamic force and working mechanism of internal pressures of the cooling tower under the most unfavorable working condition are compared between the four ventilation rates of shutters (0%, 15%, 30% and 100%). The results show that the amount of raindrops captured by the internal surface of the tower decreases as the wind velocity increases, and increases along with the rainfall intensity and ventilation rate of the shutters. The maximum value of rain-induced pressure coefficient is 0.013. The research findings lay the basis for determining the precise values of internal surface loads of cooling tower under extreme weather conditions.

• PNF and Movement
• /
• v.19 no.1
• /
• pp.147-152
• /
• 2021

Purpose: This study was conducted to investigate the functional differences of the two heads of the biceps brachii by measuring the functions in supination according to pronation by the angle of the flexion of the elbow joint, except for the activities of the elbow flexors. Methods: This study was conducted with 25 healthy men in their 20s. At a glenohumeral-joint 0˚ flexion posture, angles of flexion of the elbow joint of 0˚, 30˚, 60˚, 90˚, and 120˚ were randomly provided, and they were asked to perform supination and pronation with an elastic band. Using an eight-channel surface electromyogram, the muscle activities of the long and short heads of the biceps brachii were measured. The activities of the short and long heads according to the angle were analyzed using a one-way ANOVA, and as a post-test, LSD was employed. Results: The analysis of the impact of the resistance of the elastic band in supination on the differences in the muscle activities in the short and long heads suggests there was a significant difference between 0˚ and 30˚ (p < 0.05). Conclusion: In supination according to forearm pronation, the long head had greater action in the early flexion posture of the elbow joint, and it is judged that the ratio of the flexion of the elbow joint according to the actions of the biceps brachii was considered small.

• Journal of The Geomorphological Association of Korea
• /
• v.24 no.1
• /
• pp.105-116
• /
• 2017

This article is written in the viewpoint of landscape ecological geography. The coast of South Chung-chong Province will make new characters of region in the development strategies program. This study is to describe geomorphological landscapes of South Chung-chong Province relating with it's environment based on the coast. Although landforms constitute prominent landscape features as tidal flats and rock cliff do, it is nonetheless the features such as beaches, sanddunes, and coastal plains that have various ramifications for human communities. Tidal flats, beaches and coastal sanddunes are special in that their formation is attributable to the combined action of tidal flows, waves and winds. To some extent, the erosion of sand has been a global phenomenon. Human impact are involved. The influence of globalization and expansion of liberal trade appears in regions variously. Individual regions need to secure its competitiveness in the world market. Regions are not value-neutral abstract conception, but must be informal commercialized characters of region. The coast of South Chung-chong Province has experienced rapid and dramatic changes. In industrial times, the middle of west coast Korea turned into a major reclamation at larger scale. Reclaimed land was based on location of industry and mechanized agriculture. The west coast highway and bridges between island and land contributed to the development of west coast transportation. As information society matured, trend and value are changing. Environment and ecology emphasize and rediscover the value of tidal flats and sanddunes. The west coast region now receives attention as eco-tour and sustainable course.

• Journal of Korea Society of Industrial Information Systems
• /
• v.27 no.2
• /
• pp.101-113
• /
• 2022

The intensification and acceleration of severe competition among companies due to the advancement of the service industry have raised the quality level of services required by consumers, and these circumstances also have a significant impact on the public fields' service provision environment, which has to take into account the rapidly changing technologies along with the special situation of COVID-19. Thus, this study examines the applicability of the educational material based on the framework for public service quality management in accordance with 『ISO18091:2019』 developed by MOIS(the ministry of interior and safety), through a survey after training workers in public institutions. This study also provides some implications and guidelines that should be considered to increase the level of public service quality from the following three perspectives: i) data utilization and verification, ii) broadness of public services, and iii) the size and capability of service provider according to the results of field studies conducted with public sector employees who participated in actual improvement activities.