• Title/Summary/Keyword: immunity improvement

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The Characteristics of MOSFET with Reoxidized Nitrided Oxide Gate Dielectrics (재산화된 질화 산화막을 게이트 절연막으로 사용한 MOSFET의 특성)

  • 양광선;박훈수;김봉렬
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.28A no.9
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    • pp.736-742
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    • 1991
  • N$^{+}$poly gate NMOSFETs and p$^{+}$ poly gate (surface type) PMOSFETs with three different gate oxides(SiO2, NO, and ONO) were fabricated. The rapid thermal nitridation and reoxidation techniques have been applied to gate oxide formation. The current drivability of the ONO NMOSFET shows larger values than that of the SiO2 NMOSFET. The snap-back occurs at a lower drain voltage for SiO$_2$ cases for ONO NMOSFET. Under the maximum substrate current bias conditions, hot-carrier effects inducting threshold voltage shift and transconductance degradation were investigated. The results indicate that ONO films exhibit less degradation in terms of threshold voltage shift. It was confirmed that the ONO samples achieve good improvement of hot-carrier immunity. In a SiO$_2$ SC-PMOSFET, with significant boron penetration, it becomes a depletion type (normally-on). But ONO films show excellent impurity barrier properties to boron penetration from the gate.

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Antitumor Effects of Glycoportein Extracted from Sea Cucumber (Stichopus japonicus)

  • Moon, Jeung-Hye;Ryu, Hong-Sool;Suh, Jae-Soo
    • Preventive Nutrition and Food Science
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    • v.4 no.2
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    • pp.117-121
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    • 1999
  • The anititumor and immunologic activities of the glycoproteins extracted from sea cucumber (Stichopus japonicus) on mice bearing sarcoma 180 cells were investigated . Maximum tumor suppression (64%) occurred at the dose of 100mg glycoprotein/kg. The highest prolongation ratio was achieved at the level of 100mg/kg an dincreased by 395 more than that of control. Glycoproteins from sea cucumber exhibited direct cytotoxic effect on the tumor cells. Dose dependent increase of leucocyte, peritoneal exudate cell and weights of immunoorgans revealed the improvement of immunity. When the glycoportein-administered group was compared with the control, a significant difference was not noted in the clinico-chemical values such as S-GOT, S-GPT , alkaline phoshatse activity, total protein, cholesterol, triglyceride, urea nitrogen and glucose levels in blood. These results suggests that the antitumor activity of sea cucumber glycoprotein is associated with activation of cells in the immune system.

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A Study on Steering Performance Improvement of the AGV using Cell-Mediated Immune Algorithm (세포성 면역 알고리즘을 이용한 AGV의 조향 성능 향상에 관한 연구)

  • Lee, Y.J.;Sohn, J.H.;Lee, J.W.;Cho, H.C.;Lee, K.S.
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.2572-2574
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    • 2000
  • In this paper, cell-mediated immune algorithm(CMIA) controller was proposed and applied for the autonomous guided vehicle(AGV) driving. It was based on specific immune response of the biological immune system which is the cell-mediated immunity. To verify the performance of the designed CMIA controller, some experiments were performed for the control of steering and speed of AGV. And then the displacement and speed tracking error of the AGV was mainly investigated. As results, the capability of realization and reliableness were proved by comparing the response characteristics of the classical controller with the proposed CMIA controller.

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Immunopotentiating Effect of Polysaccharide Produced from a Mutant of Acetobacter pasteurianus (I) (Acetobacter pasteurianus 변이주가 생산하는 다당류의 면역효과(I))

  • 김동석;정연봉조덕제류병호
    • KSBB Journal
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    • v.7 no.1
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    • pp.39-44
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    • 1992
  • Dose-dependent responses indicated by the increase of leukocyte, peritoneal exudate cell and weights of immunorgans revealed the improvement of immunity. In the effect of macrophage on phagocytes, there were not substantial differences in the phagocytic and corrected phagocytic index. The administered group being compared with the controlled group, there were no significant changes in SGOT, S-GPT, alaline phosphatase, total protein, albumin, globulin, cholesterol, triglyceride, blood urea nitrogen and glucose. Key words: dose-dependent responses, peritoneal exudate cell, phagocytic idex, corrected phagocytic index.

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Improvement of Power Capability and Field Uniformity with Tapered Coaxial Matching Units in Strip Line for Measuring Electromagnetic Immunity of Vehicular Components

  • Chung, Yeon-Choon;Kang, Tae-Won;Park, Dong-Chul
    • Journal of Electrical Engineering and information Science
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    • v.2 no.5
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    • pp.60-64
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    • 1997
  • The design process and construction method of a strip line is described for measuring radiated susceptibility of vehicular components having electrical cables more than 2 min length. he characteristic impedance of the trip line was determined 90$\Omega$ to obtain the field uniformity of $\leq$${\pm}$3 dB in the frequency range from 100 kHz to 500 MHz. Tapered coaxial lines were used instead of the traditional lumped circuit element for the impedence matching units, therefore, the strip line has high power capability. Using these techniques, the field uniformity and power capability of a strip line could be considerably improved.

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History of the Korean fermented milk industry (우리나라 발효유 산업의 역사)

  • Shin, Youngsup
    • Food Science and Industry
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    • v.54 no.4
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    • pp.278-292
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    • 2021
  • Fermented milk including yogurt, which has a long tradition of thousands of years, was first established in Korea in 1919, and the current market size has grown to over 90 billion dollars. Fermented milk, which began in the early days of liquid yogurt, appeared on the market as spoonable and drinking yogurt. Fermented milk began with research on intestinal health functions and lactobacilli, and gradually developed into various disease prevention studies such as gastrointestinal health, immunity improvement, skin beauty, and prevention of dementia. As a simple meal, it has a nutrient function element, which serves as a meal replacement, and is expanding its range from general foods to special-purpose foods and dietary supplements. Fierce market competition is taking place, and as a result, the domestic fermented milk market is developing through the development of various products for differentiation.

Effects of Citurs unshiu Markovich on growth performance and bactericidal activity of nile tilapia Oreochromis niloticus (진피(Citurs unshiu Markovich)추출물이 틸라피아(Oreochromis niloticus)의 성장률 및 항균효과에 미치는 영향)

  • Bang, Seok Jin;Lee, Chan Heun;Kang, Tae Yun;Choi, Jae Hyeok;Jung, Sang Mok;Kang, In Sung;Park, Kwan Ha;Choi, Sang Hoon
    • Journal of fish pathology
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    • v.32 no.2
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    • pp.105-111
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    • 2019
  • Citurs unshiu Markovich is a medicinal product of dried tangerine peel (DTP). It is effective on antioxidation, and getting fame as a medicine and functional food. By utilizing DTP as a feed additive, we aim to enhance the growth rate, innate immunity, and bacterial infection resistance to Tilapia. The DTP extract was added to the feed weight by 0.1, 0.5, 1, 5% and then fed to tilapia for 7 days to evaluate the innate immunity parameter, growth rate and anti-bacterial activity. Innate immunity parameter results showed that the ROI was significantly higher in the 5% group added at high concentration, while showing decrease or no differences in other experimental groups. In other parameters, all the experimental groups showed no significant difference or decreased compared to the control group. The challenge test showed a high survival rate of 71% in the 0.5% group and the lowest in the control group (36%). For the growth rate, the feed efficiency was improved in all groups except for the 0.1% group compared to the control group. In conclusion, DTP extract has bacterial resistant effect in while not affecting innate immune system of fish. Also, it has shown the potential as a possible feed additive as it has brought the improvement on feed efficiency ratio.

Moderating Effects and Maintenance of Lung Cancer Cellular Immune Functions by CIK Cell Therapy

  • Jin, Cong-Guo;Chen, Xiao-Qun;Li, Jia;Wu, Zhi-Pin;Liu, Xin;Wang, Xi-Cai
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3587-3592
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    • 2013
  • Aims: To study the CIK cell treatment effects on regulation of cellular immune function disorders in patients with lung cancer, and to analyze the time characteristics. Methods: Cellular immune function was assessed by FCM, and patients with functional disorders were randomly divided into two groups, one given CIK cell therapy within 18 months (5 courses) and the other the controls, which were followed up for 1 year with cellular immune functions tested once a month. Results: There were 5 types of cellular immunity, 4 of which are disorders; after CIK treatment, the improvement rate of the 4 groups were 79.1%, 70.8%, 76.0% and 70.0%, intergroup differences not being statistically significant (P=0.675), all significantly higher than in the control group (P=0.000). The median maintenance times for the 4 groups were 10.4 months (9.76-11.04), 8.4 months (7.86-8.94), 9.8 months (9.20-10.4) and 7.9 months (6.25-9.55), respectively. Conclusions: CIK cells were able to improve the immune functions of patients with lung cancer, the rate of improvement and maintenance time being related to the immune function before the treatment and CIK-cell-therapy courses.

A Regression of Miller Fisher Syndrome using Photic Feedback: Possibility of a New Complementary Therapy

  • Kamei, Tsutomu;Toriumi, Yoshitaka;Kumano, Hiroaki;Yasushi, Mitsuo
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.530-533
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    • 2002
  • We present a case of The Miller Fisher Syndrome (MFS), showing a remission during a recently developed noninvasive therapy. Two weeks after an appearance of cough and fever, a 35 years old Japanese male developed diplopia, ataxia and numbness of his fingers and toes. He was diagnosed as MFS, and a fixed dose of prednisolone acetate (60mg/day) was administered for 3 months, but little improvement was observed. In addition to this administration, we tried 20 minutes of Photic Feedback (PFB) treatment daily for 40 days. The PFB system detects brain waves from the subject's forehead, and extracts alpha waves by the band-pass filter with a center frequency set at 10.0Hz. It also simultaneously modulates the augmentation of a red light-emitting diode, corresponding with the amplitudes of the extracted alpha waves. In this treatment, this adjusted photic stimulation was given to the subject's closed eyes, resulting in the effective alpha enhancement by photic driving response. The numbness increased during each of PFB treatment, but the symptoms started to improve gradually after 10 days. Other symptoms disappeared after 40 days. CD20 levels increased with this treatment. This case suggests that the PFB treatment may speed the natural remission of MFS. This treatment may be worth considering in patients who suffer polyneuropathy.

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Analytical Modeling and Simulation for Dual Metal Gate Stack Architecture (DMGSA) Cylindrical/Surrounded Gate MOSFET

  • Ghosh, Pujarini;Haldar, Subhasis;Gupta, R.S.;Gupta, Mridula
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.12 no.4
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    • pp.458-466
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    • 2012
  • A Dual metal gate stack cylindrical/ surrounded gate MOSFET (DMGSA CGT/SGT MOSFET) has been proposed and an analytical model has been developed to examine the impact of this structure in suppressing short channel effects and in enhancing the device performance. It is demonstrated that incorporation of gate stack along with dual metal gate architecture results in improvement in short channel immunity. It is also examined that for DMGSA CGT/SGT the minimum surface potential in the channel reduces, resulting increase in electron velocity and thereby improving the carrier transport efficiency. Furthermore, the device has been analyzed at different bias point for both single material gate stack architecture (SMGSA) and dual material gate stack architecture (DMGSA) and found that DMGSA has superior characteristics as compared to SMGSA devices. The analytical results obtained from the proposed model agree well with the simulated results obtained from 3D ATLAS Device simulator.