• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 제5회 학술대회 논문집 일렉트렛트 및 응용기술연구회
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• pp.33-37
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• 2003

Endovaginal and endorectal receiver only surface coil were designed for MR imaging(MRI) and $^1H$ MR spectroscopy(MRS) for the uterine cervix and the prostate. The shape of endovaginal coil wire was rectangular with round comer. The shape of endorectal coil wire was long elliptic shape during insertion and circular shape after insertion. Conventional spin echo and fast spin echo sequences were used as T1 and T2 weighted imaging sequences, respectively. 3D volume localized in vivo $^1H$ MR spectroscopy of the human cervix and prostate was performed using PRESS or STEAM localization method. Using home-built endvaginal and endorectal coils, excellent T1 and T2 images were obtained to visualize early cervical and prostate tumors. 3D volume localized in vivo $^1H$ MRS was useful to differentiate the cancerous tissue from the normal tissue.

• Korean Journal of Radiology
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• 제20권1호
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• pp.18-33
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• 2019

In this study, we summarize the clinical role of magnetic resonance imaging (MRI) in the diagnosis of patients with malignant uterine neoplasms, including leiomyosarcoma, endometrial stromal sarcoma, adenosarcoma, uterine carcinosarcoma, and endometrial cancer, with emphasis on the challenges and disadvantages. MRI plays an essential role in patients with uterine malignancy, for the purpose of tumor detection, primary staging, and treatment planning. MRI has advanced in scope beyond the visualization of the many aspects of anatomical structures, including diffusion-weighted imaging, dynamic contrast enhancement-MRI, and magnetic resonance spectroscopy. Emerging technologies coupled with the use of artificial intelligence in MRI are expected to lead to progressive improvement in case management of malignant uterine neoplasms.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1521-1521
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• 2001

The objective of the research being presented was to construct and calibrate a spectrometer for the analysis of single kernels of corn. In light of the difficulties associated with capturing the spatial variability in composition of corn kernels by single-beam spectrometry, a hyperspectral imaging spectrometer was constructed with the intention that it would be used to analyze single kernels of corn for the prediction of moisture and oil content. The spectrometer operated in the range of 750- 1090 nanometers. After evaluating four methods of standardizing the output from the spectrometer, calibrations were made to predict whole-kernel moisture and oil content from the hyperspectral image data. A genetic algorithm was employed to reduce the number of wavelengths imaged and to optimize the calibrations. The final standard errors of prediction during cross-validation (SEPCV) were 1.22% and 1.25% for moisture and oil content, respectively. It was determined, by analysis of variance, that the accuracy and precision of single-kernel corn analysis by hyperspectral imaging is superior to the single kernel reference chemistry method (as tested).

• 한국자기공명학회논문지
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• 제19권3호
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• pp.124-131
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• 2015

Hyperpolarization methods are the most emerging techniques in the field of magnetic resonance (MR) researches since they make a contribution to overcoming sensitivity limitation of MR spectroscopy and imaging, leading to new fields of researches, real-time in vivo metabolic/molecular imaging and MR analysis of chemical/biological reactions in non-equilibrium conditions. Make use of enormous signal enrichments, it becomes feasible to investigate various chemical and biochemical systems with low ${\gamma}$ nuclei in real-time. This review deals with the theoretical principals of common hyperpolarization methods and their experimental features. In addition, more detailed theories, mechanisms, and applications of dissolution dynamic nuclear polarization (D-DNP) are discussed.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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• pp.302-305
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• 2007

During the CareBeijing campaign in September 2006, Imaging Differential Optical Absorption Spectroscopy (IDOAS) measurements were made over the city of Beijing, China using a spatial resolution of 146 pixels horizontally and 61 pixels vertically, each with a field of view of $0.133^{\circ}$ and $0.072^{\circ}$ in the horizontal and vertical directions, respectively. Using Fraunhofer reference spectra (FRS) for the evaluation of data for two consecutive days, the diurnal variation of $NO_2$ distributions was determined from data measured every single hour from 08:00 until 16:00 on September 9 and 10. Both days presented a fairly clear sky with high visibility. The setup allowed detailed images of the low surface $NO_2$ distribution over Beijing. Images with less than a 30-min temporal resolution showed variation of plume dispersal in both horizontal and vertical directions. An in-situ measurement was also conducted. Results from both instruments are interpreted by considering local emission sources and wind conditions.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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• pp.15-19
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• 2001

지난 10년간 신경계의 MR영상은 컴퓨터를 비롯한 하드웨어적인 발달에 힘입어 functional imaging, perfusion imaging, diffusion imaging, MR spectroscopy, MR angiography 등의 분야에서 괄목한 만한 성장이 있었다. 지난 2001년 4월 국제자기공명의과학회 (ISMRM) 학술대회에 약 2300개의 논문이 발표되었으며 이 중 신경계와 관련된 논문의 수는 저자가 파악하기에 약 500개 정도이었다. 매년 수많은 논문이 발표되고 있으나 이 중 기초 또는 임상의학적으로 유용한 논문만이 후속 연구로 연결되어 궁극적으로 많은 사람들이 활용할 수 있게 되고 있다. 따라서 지난 수 년 동안의 연구 동향을 모두 follow-up하는 것은 무의미하며, 이 중 functional, perfusion, diffusion imaging을 중심으로 이들 영상 기법의 기술적 측면과 적용 분야를 알아보고자 한다.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.218-228
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• 2021

Due to their high degree of freedom to transfer and acquire light, fiber optics can be used in the presence of strong magnetic fields. Hence, optical sensing and imaging based on fiber optics can be integrated with magnetic resonance imaging (MRI) diagnostic systems to acquire valuable information on biological tissues and organs based on a magnetic field. In this article, we explored the combination of MRI and optical sensing/imaging techniques by classifying them into the following topics: 1) functional near-infrared spectroscopy with functional MRI for brain studies and brain disease diagnoses, 2) integration of fiber-optic molecular imaging and optogenetic stimulation with MRI, and 3) optical therapeutic applications with an MRI guidance system. Through these investigations, we believe that a combination of MRI and optical sensing/imaging techniques can be employed as both research methods for multidisciplinary studies and clinical diagnostic/therapeutic devices.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1526-1526
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• 2001

To improve the accuracy of sweetness sensor in automated sorting operations, it is necessary to clarify unevenness of the sugar content distribution within fruits. And it is expected that the technique to evaluate the content distribution in fruits contribute to the development of the near-infrared (NIR) imaging spectroscopy. Sugiyama (1999) had succeeded to visualize the distribution of the sugar content on the surface of a half-cut green fresh melon. However, this method cannot be applied to red flesh melons because it depends on information of the absorption band of chlorophyll (676 nm), which is affected by the color of the fresh. The objective of this study was to develop the universal visualization method depends on the absorption band of sugar, which can be applied to various kinds of melons and other fruits. The relationship between the sugar contents and absorption spectra of both green and red fresh melons were investigated by using a NIR spectrometer to determine the absorption band of sugar. The combination of 2$\^$nd/ derivative absorbances at 902 nm and 874 nm was highly correlated with the sugar contents. The wavelength of 902 nm is attributed to the absorption band of sugar. A cooled charge-coupled device (CCD) imaging camera which has 16 bit (65536 steps) A/D resolution was equipped with rotating band-pass filter wheel and used to capture the spectral absorption images of the flesh of a vertically half-cut red fresh melon. The advantage of the high A/D resolution in this research is that each pixel of the CCD is expected to function as a detector of the NIR spectrometer for quantitative analysis. Images at 846 nm, 874 nm, 902 nm and 930 nm were acquired using this CCD camera. Then the 2$\^$nd/ derivative absorbances at 902 nm and 874 nm at each pixel were calculated using these four images. On the other hand, parts of the same melon were extracted for capturing the images and squeezed for the measurement of sugar content. Then the calibration curve between the combination of 2$\^$nd/ derivative absorbances at 902 nm and 874 nm and sugar content was developed. The calibration method based on NIR spectroscopy techniques was applied to each pixel of the images to convert the 2$\^$nd/ derivative absorbances into the Brix sugar content. Mapping the sugar content value of each pixel with linear color scale, the distribution of the sugar content was visualized. As a result of the visualization, it was quantitatively confirmed that the Brix sugar contents are low at the near of the skin and become higher towards the seeds. This result suggests that the visualization technique by the NIR imaging spectroscopy could become a new useful method fer quality evaluation of melons.

• Investigative Magnetic Resonance Imaging
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• 제7권1호
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• pp.31-38
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• 2003

목적 : 실험적으로 토끼 대퇴부에 유발한 농양에서 연속적 추적검사를 통하여 MRS 스펙트럼의 특징과 항생제 치료에 따른 대사산물의 변화를 분석하고자 하였다. 대상 및 방법 : 토끼 10마리의 대퇴부에 흰쥐의 대변으로부터 추출한 용액을 주사하여서 농양을 유발시켰고, 대조군 5마리와 항생제 치료군 5마리로 나누어 4주 동안 1주 간격으로 MRI와 MRS로 추적 검사를 하였다 MRI에서는 농양의 모양과 크기를 분석하였으며, 기존 문헌을 참조하여 MRS에서 보이는 대사산물의 스펙트럼을 분류하였다. N-acetyl alanine을 외적기준으로, lipid를 내적기준으로 하여 각 대사산물을 정량 분석하였고, 정량화된 값들이 농양의 시기에 따라 대조군과 치료군 사이에 차이가 있는지를 분석하였다. 결과 : MRI에서 농양 10 예 모두는 낭성 종괴로 보였으며, 크기는 22-77 mm였다. MRS에서는 감염을 시사하는 acetate, succinate와 여러 종류의 아미노산 peak가 대조군, 치료군 모두에서 여러 가지 조합으로 검출되었다. 그 중 1.92 ppm의 acetate(70%)가 가장 흔하게 보였다. Lipid peak에 대한 acetate peak 비율과 외적기준의 peak에 대한 acetate peak 비율은 대조군에서는 시기에 따라 큰 변화가 없는 반면에 치료군에서는 감소하는 경향이 있었다. 결론 : MRS는 농양에서 감염을 시사하는 대사산물을 검출함으로써 진단에 도움을 줄 수 있을 뿐 아니라 acetate peak는 농양의 진행 및 항생제 치료에 의해 영향을 받아서 농양의 활동도 지표로서 유용한 가치가 있을 것으로 사료된다.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.25-25
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• 2003

Purpose： In order to characterise primary central nervous system Iymphomas (PCNSL) and to evaluate if 1H spectroscopy improves the preoperative differential diagnosis of other diseases. Method： We reviewed 11 MR imaging and 7 MR spectroscopy of 9 patient with Iymphoma confirmed by stereotatic biopsy.