• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.341-344
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• 2002

Neurodegenerative disorders, like Alzheimer's disease, are often accompanied by reduced brain perfusion (cerebral blood flow). Using the intrinsic magnetic properties of water, arterial spin labeling magnetic resonance imaging (ASLMRI) can map brain perfusion without injection of radioactive tracers or contrast agents. However, accuracy in measuring perfusion with ASL-MRI can be limited because of contributions to the signal from stationary spins and because of signal modulations due to transient magnetic field effects. The goal was to optimize ASL-MRI for perfusion measurements in the aging human brain, including brains with Alzheimer's disease. A new ASL-MRI sequence was designed and evaluated on phantom and humans. Image texture analysis was performed to test quantitatively improvements. Compared to other ASL-MRI methods, the newly designed sequence provided improved signal to noise ratio improved signal uniformity across slices, and thus, increased measurement reliability. This new ASL-MRI sequence should therefore provide improved measurements of regional changes of brain perfusion in normal aging and neurodegenerative disorders.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.376-378
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• 2002

This work was carried out to evaluate the basic performances for 4D CT, which employed continuously rotating conebeam. The performances were evaluated with the same method as the conventional CT, because the standard method of evaluating 4D CT has not yet been established, and we think this result was helpful to establish it. 4D CT can give dynamic volume imaging data continuously and with high-speed. The results were isotropic except for the evaluation of distortion in which small distortions gradually appeared as coming off the center of phantom in longitudinal direction.

• Journal of electromagnetic engineering and science
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• 제17권4호
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• pp.169-177
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• 2017

The role of electromagnetic (EM) waves in magnetic fusion plasma-ranging from radio frequency (RF) to microwaves-has been extremely important, and understanding of EM wave propagation and related technology in this field has significantly advanced magnetic fusion plasma research. Auxiliary heating and current drive systems, aided by various forms of high-power RF and microwave sources, have contributed to achieving the required steady-state operation of plasmas with high temperatures (i.e., up to approximately 10 keV; 1 eV=10000 K) that are suitable for future fusion reactors. Here, various resonance values and cut-off characteristics of wave propagation in plasmas with a nonuniform magnetic field are used to optimize the efficiency of heating and current drive systems. In diagnostic applications, passive emissions and active sources in this frequency range are used to measure plasma parameters and dynamics; in particular, measurements of electron cyclotron emissions (ECEs) provide profile information regarding electron temperature. Recent developments in state-of-the-art 2D microwave imaging systems that measure fluctuations in electron temperature and density are largely based on ECE. The scattering process, phase delays, reflection/diffraction, and the polarization of actively launched EM waves provide us with the physics of magnetohydrodynamic instabilities and transport physics.

• 한국의학물리학회지:의학물리
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• 제27권4호
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• pp.236-240
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• 2016

The purpose of this study is to propose a novel high sensitivity neuro-PET design. The improvement of sensitivity in neuro-PET is important because it can reduce scan time and/or radiation dose. In this study, we proposed a novel PET detector design that combined conical shape detector with cylindrical one to obtain high sensitivity. The sensitivity as a function of the oblique angle and the ratio of the conical to cylindrical portion was estimated to optimize the design of brain PET using Monte Carlo simulation tool, GATE. An axial sensitivity and misplacement rate by penetration of ${\gamma}$ rays were also estimated to evaluate the performance of the proposed PET. The sensitivity was improved by 36% at the center of axial FOV. This value was similar to the calculated value. The misplacement rate of conical shaped PET was about 5% higher than the conventional PET. The results of this study demonstrated the conical detector proposed in this study could provide subsequent improvement in sensitivity which could allow to design high sensitivity PET for brain imaging.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2005년도 제30회 춘계학술대회
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• pp.89-92
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• 2005

The effects of acupuncture are complex and how it works is not entirely clear. Research suggests that the needling process, and other modalities used in acupuncture, may produce their complex effects on a wide variety of ways in the brain and the body. For example, it is theorized that stimulated nerve fibers transmit signals to the spinal cord and brain, thus activating parts of what is called the central nervous system. The spinal cord and brain then release certain hormones responsible for making us feel better overall and, more specifically, feel less pain. In fact, a study using images of the brain confirmed that acupuncture increases our pain threshold, which may explain its ability to produce long-term pain relief. Also, acupuncture may increase blood circulation and body temperature. It may also affect white blood cell activity (responsible for our immune function).

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2005년도 제30회 춘계학술대회
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• pp.93-95
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• 2005

자기공명분광법은 극소의 체적내애서 핵자기공명에 의하여 생화학적 성질들을 고유한 주파수에 따라서 대사물질의 신호를 얻는다. 핵자기공명의 신호는 경사자장 혹은 주파수의 크기를 조절하여 체내의 조직성분을 충분히 포함하여 통과시킨다. 획득되어진 원래 데이터는 TE, TR 등의 물리적 상수값의 변화에 의해서 영향을 받는다. 최근의 펄스 시퀀스는 고해상도 3D CSI 및 SVS가 국소적인 체적내의 대사물질의 변화량을 정성적으로 감지하므로 임상데이터로 활용하기 위한 연구가 더욱 절실하다.

• 천문학회보
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• 제36권2호
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• pp.78.1-78.1
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• 2011

We report on a photometric study of star clusters in the circumnuclear star-forming region of nearby barred spiral galaxy NGC 1672. We use FUV to NIR imaging data (FUV, U, B, V, R, $H{\alpha}$, I, and H) in the Hubble Space Telescope (HST) archive. We have selected 89 star clusters with V<21.8 (MV<-9) mag in the central 600 pc region, and have derived their age & mass by comparing their colors with theoretical population synthesis models. Most of the star clusters are mildly reddened (E(B-V)~0.2 on average), but some star clusters suffer from severe reddening (E(B-V)>0.6). The mass of the star clusters are in the range from $10^4\;M_{\odot}$ to $10^7\;M_{\odot}$. About half of them are more massive than $10^5\;M_{\odot}$. Their ages range from 1 Myr to several 100 Myr, and concentrate at ~6 Myr and ~40 Myr. It indicates that the episodic starburst in the circumnuclear star-forming region lasted at least several 100 Myr. We find no obvious azimuthal age gradient, but we find a radial age gradient in some regions. We discuss these properties with theoretical expectations.

• 한국광학회지
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• 제22권2호
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• pp.72-76
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• 2011

반도체 광 증폭기와 파브리-페롯 가변 필터를 이용한 파장 훑음 레이저 기반 광 결맞음 단층 촬영을 구성하고, 이로부터 선명한 이미징을 얻기 위한 파수 영역 선형화를 구현하였다. 파수 영역 선형화는 5 개의 서로다른 공진 파장을 가진 광섬유 격자로 이루어진 어레이를 이용하여 보간법으로 수행하였다. 샘플단의 1 mm 깊이에서 파수 영역 선형화를 수행한 후 점 분포 함수(point spread function)로부터 측정한 SNR(signal-to-noise ratio)은 12 dB 향상된 값을 얻어냈다. 또한 파수 영역 선형화 전과 후에 대해 슬라이드 글라스를 이용하여 OCT 이미징을 얻어낸 결과 파수 영역 선형화가 매우 잘 되었음을 확인할 수 있었다.

• 대한화학회지
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• 제61권1호
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• pp.12-15
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• 2017

We presented a mapping the work function of the vanadium pentoxide ($V_2O_5$) nanonet structures by scanning Kelvin probe microscopy (SKPM). In this measurement, the $V_2O_5$ nanonet was self-assembled via dropping the solution of $V_2O_5$ nanowires (NWs) onto the $SiO_2$ substrate and drying the solvent, resulting in the networks of $V_2O_5$ NWs. We found that the SKPM signal as a surface potential of $V_2O_5$ nanonet is attributed to the contact potential difference (CPD) between the work functions of the metal tip and the $V_2O_5$ nanonet. We generated the histograms of the CPD signals obtained from the SKPM mapping of the $V_2O_5$ nanonet as well as the highly ordered pyrolytic graphite (HOPG) which is used as a reference for the calibration of the SKPM tip. By using the histogram peaks of the CPD signals, we successfully estimated the work function of ~5.1 eV for the $V_2O_5$ nanonet structures. This work provides a possibility of a nanometer-scale imaging of the work function of the various nanostructures and helps to understand the electrical characteristics of the future electronic devices.

• 천문학회보
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• 제38권1호
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• pp.53-53
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• 2013

We present preliminary results of far-infrared(FIR) study of the supernova remnant(SNR)s in the Large Magellanic Cloud using the Herschel HERITAGE (HERschel Inventory of The Agents of Galaxy Evolution) data set. HERITAGE provides FIR data covering the entire LMC at 100,160, 250, 350, and 500 um. In order to confirm FIR emission associated with SNRs, we refer to Magellanic Cloud Emission-Line Survey (MCELS) H-alpha & SII data, Spitzer surveying the Agents of a Galaxy's Evolution (SAGE) Multiband Imaging Photometer (MIPS) 24um & 70um data, Chandra Supernova Remnants Catalog, and ATCA 4.8GHz continuum images of Dickel et al. (2005). Among 47 SNRs in the LMC, 7 SNRs show associated FIR emission. We present multi-wavelength view of 5 SNRs; DEM L249, N49, N63A, N132D, and the SNR in N4. N49 and N132D show morphological correlation in FIR and X-ray, suggesting that the FIR emission is from dust grains collisionally heated by X-ray emitting plasma. The FIR emission of N63A resembles H-alpha emission, which implies that the FIR line radiation could be dominant. The FIR images of the rest two objects, DEM L249 and SNR in N4, show no correlation to the other-waveband images.