• Title/Summary/Keyword: imaging material

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The Effects of Electron Beam Exposure Time on Transmission Electron Microscopy Imaging of Negatively Stained Biological Samples

  • Kim, Kyumin;Chung, Jeong Min;Lee, Sangmin;Jung, Hyun Suk
    • Applied Microscopy
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    • v.45 no.3
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    • pp.150-154
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    • 2015
  • Negative staining electron microscopy facilitates the visualization of small bio-materials such as proteins; thus, many electron microscopists have used this conventional method to visualize the morphologies and structures of biological materials. To achieve sufficient contrast of the materials, a number of imaging parameters must be considered. Here, we examined the effects of one of the fundamental imaging parameters, electron beam exposure time, on electron densities generated using transmission electron microscopy. A single site of a negatively stained biological sample was illuminated with the electron beam for different times (1, 2, or 4 seconds) and sets of micrographs were collected. Computational image processing demonstrated that longer exposure times provide better electron densities at the molecular level. This report describes technical procedures for testing parameters that allow enhanced evaluations of the densities of electron microscopy images.

Photon-Counting Detector CT: Key Points Radiologists Should Know

  • Andrea Esquivel;Andrea Ferrero;Achille Mileto;Francis Baffour;Kelly Horst;Prabhakar Shantha Rajiah;Akitoshi Inoue;Shuai Leng;Cynthia McCollough;Joel G. Fletcher
    • Korean Journal of Radiology
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    • v.23 no.9
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    • pp.854-865
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    • 2022
  • Photon-counting detector (PCD) CT is a new CT technology utilizing a direct conversion X-ray detector, where incident X-ray photon energies are directly recorded as electronical signals. The design of the photon-counting detector itself facilitates improvements in spatial resolution (via smaller detector pixel design) and iodine signal (via count weighting) while still permitting multi-energy imaging. PCD-CT can eliminate electronic noise and reduce artifacts due to the use of energy thresholds. Improved dose efficiency is important for low dose CT and pediatric imaging. The ultra-high spatial resolution of PCD-CT design permits lower dose scanning for all body regions and is particularly helpful in identifying important imaging findings in thoracic and musculoskeletal CT. Improved iodine signal may be helpful for low contrast tasks in abdominal imaging. Virtual monoenergetic images and material classification will assist with numerous diagnostic tasks in abdominal, musculoskeletal, and cardiovascular imaging. Dual-source PCD-CT permits multi-energy CT images of the heart and coronary arteries at high temporal resolution. In this special review article, we review the clinical benefits of this technology across a wide variety of radiological subspecialties.

THE EFFECT OF SURFACE ROUGHNESS OF CSI(TL) MICRO-COLUMNS ON THE RESOLUTION OF THE X-RAY IMAGE; OPTICAL SIMULATION STUDY

  • Kim, Hyun-Ki;Bae, Jun-Hyung;Cha, Bo-Kyung;Jeon, Ho-Sang;Kim, Jong-Yul;Kim, Chan-Kyu;Cho, Gyu-Seong
    • Journal of Radiation Protection and Research
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    • v.34 no.1
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    • pp.25-30
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    • 2009
  • Micro-columnar CsI(Tl) is the most popular scintillator material which is used for many indirect digital X-ray imaging detectors. The light scattering at the surface of micro-columnar CsI(Tl) scintillator was studied to find the correlation between the surface roughness and the resultant image resolution of indirect X-ray imaging detectors. Using a commercially available optical simulation program, Light Tools, MTF (Modulation Transfer Function) curves of the CsI(Tl) film thermally evaporated on glass substrate with different thickness were calculated and compared with the experimental estimation of MTF values by the edge X-ray image method and CCD camera. It was found that the standard deviation value of Gaussian scattering model which is determined by the surface roughness of micro-columns could certainly change the MTF value of image sensors. This model and calculation methodology will be beneficial to estimate the overall performance of indirect X-ray imaging system with CsI(Tl) scintillator film for optimum design depending on its application.

A Study on the Insertional Coil of MRI Device for Diagnosis (진단용 자기공명영상장치의 삽입 코일에 관한 연구)

  • Lee, Yong-Moon;Lim, Keun-Ho;Seo, Dae-Keon;Kim, Wang-Gon;Hong, Jin-Woong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05d
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    • pp.33-37
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    • 2003
  • Endovaginal and endorectal receiver only surface coil were designed for MR imaging(MRI) and $^1H$ MR spectroscopy(MRS) for the uterine cervix and the prostate. The shape of endovaginal coil wire was rectangular with round comer. The shape of endorectal coil wire was long elliptic shape during insertion and circular shape after insertion. Conventional spin echo and fast spin echo sequences were used as T1 and T2 weighted imaging sequences, respectively. 3D volume localized in vivo $^1H$ MR spectroscopy of the human cervix and prostate was performed using PRESS or STEAM localization method. Using home-built endvaginal and endorectal coils, excellent T1 and T2 images were obtained to visualize early cervical and prostate tumors. 3D volume localized in vivo $^1H$ MRS was useful to differentiate the cancerous tissue from the normal tissue.

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A CCD Camera Lens Degradation Caused by High Dose-Rate Gamma Irradiation (고 선량율 감마선 조사에 따른 렌즈의 열화)

  • Cho, Jai-Wan;Lee, Joon-Koo;Hur, Seop;Koo, In-Soo;Hong, Seok-Boong
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.7
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    • pp.1450-1455
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    • 2009
  • Assumed that an IPTV camera system is to be used as an ad-hoc sensor for the surveillance and diagnostics of safety-critical equipments installed in the in-containment building of the nuclear power plant, an major problem is the presence of high dose-rate gamma irradiation fields inside the one. In order to uses an IPTV camera in such intense gamma radiation environment of the in-containment building, the radiation-weakened devices including a CCD imaging sensor, FPGA, ASIC and microprocessors are to be properly shielded from high dose-rate gamma radiation using the high-density material, lead or tungsten. But the passive elements such as mirror, lens and window, which are placed in the optical path of the CCD imaging sensor, are exposed to a high dose-rate gamma ray source directly. So, the gamma-ray irradiation characteristics of the passive elements, is needed to test. A CCD camera lens, made of glass material, have been gamma irradiated at the dose rate of 4.2 kGy/h during an hour up to a total dose of 4 kGy. The radiation induced color-center in the glass lens is observed. The degradation performance of the gamma irradiated lens is explained using an color component analysis.

Medical Application of Synchrotron Radiation in Japan

  • Toyofuku, Fukai;Tokumori, Kenji;Hyodo, Kazuyuki;Ando, Masami;Uyama, Chikao
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.32-34
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    • 2002
  • Over the past two decades there has been a tremendous growth in the number of synchrotron radiation facilities in the world and also in Japan. The high flux and brightness radiation which derive from the third generation low emittance rings provide an ideal source for many applications in the medical sciences. The application of synchrotron radiation to medical imaging started in the early 80's in U.S.A, followed by European countries such as Germany and Russia. In Japan, researchs on intravenous coronary angiography started in 1884 at the Institute for High Energy Phisics(KEK) in Tsukuba. At present, it is the only application of syncrotron radiation which is at the stage of human study. In '90s, newer techniques such as phase and refraction contrast imaging appeared which are at the in vitro or animal study stage. Various types of x-ray CT have also been developed for three-dimensional imaging of the subjects. The present status of medical applications of synchrotron radiation in Japan is reviewed.

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Synthesis and Biodistribution of Cat's Eye-shaped [57Co]CoO@SiO2 Nanoshell Aqueous Colloids for Single Photon Emission Computed Tomography (SPECT) Imaging Agent

  • Kwon, Minjae;Park, Jeong Hoon;Jang, Beom-Su;Jung, Hyun
    • Bulletin of the Korean Chemical Society
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    • v.35 no.8
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    • pp.2367-2370
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    • 2014
  • "Cat's eye"-shaped $[^{57}Co]CoO@SiO_2$ core-shell nanostructure was prepared by the reverse microemulsion method combined with radioisotope technique to investigate a potential imaging agent for a single photon emission computed tomography (SPECT) in nuclear medicine. The core cobalt oxide nanorods were obtained by thermal decomposition of $Co-(oleate)_2$ precursor from radio isotope Co-57 containing cobalt chloride and sodium oleate. The $SiO_2$ coating on the surface of the core cobalt oxide nanorods was produced by hydrolysis and a condensation reaction of tetraethylorthosilicate (TEOS) in the water phase of the reverse microemulsion system. In vivo test, micro SPECT image was acquired with nude mice after 30 min of intravenous injection of $[^{57}Co]CoO@SiO_2$ core-shell nanostructure.

Design and Manufacture of Ultra-Precision Al Flat Mirror Using Thermal Image Optics (열영상 광학계용 초정밀 Al 평면 미러의 설계 및 제작)

  • Kim, Dae-Jung;Choi, Cheol-Ho;Park, Yong-Pil;Gu, Hal-Bon;Kim, Shang-Suk;Kim, Joung-Ho
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05b
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    • pp.136-139
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    • 2003
  • Thermal imaging system is electro-optical imaging device which can make visible the difference of infrared energy naturally emitted by objects. It is acquire the same images at any time of the day or night. There it has been readily available to the night observation such as fire control systems. In this study, we are manufacturing thermal image Al flat mirror. The surface roughness 3.539nm Ra and power 0.382 fringe(at 632.8nm), irregularity 0.835 fringe(at 632.8nm) for form waviness of thermal image Al flat mirror are very satisfied. The results will be reflected for development of the ultra precision application. And a brief review of Ultra-precision system in the field of Ultra-precision at Korea photonics technology institute (KOPTI) is present in this paper.

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Molding and Evaluation of Ultra-Precision Chalcogenide-Glass Lens for Thermal Imaging Camera Using Thermal Deformation Compensation (열변형 보정을 통한 열화상카메라용 초정밀 칼코지나이드 유리렌즈 몰드성형 및 특성 평가)

  • Cha, Du Hwan;Kim, Jeong-Ho;Kim, Hye-Jeong
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.27 no.2
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    • pp.91-96
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    • 2014
  • Aspheric lenses used in the thermal imaging are typically fabricated using expensive single-crystal materials (Ge and ZnS, etc.) by the costly single point diamond turning (SPDT) process. As a potential solution to reduce cost, compression molding method using chalcogenide glass has been attracted to fabricate IR optic. Thermal deformation of a molded lens should be compensated to fabricate chalcogenide aspheric lens with form accuracy of the submicron-order. The thermal deformation phenomenon of molded lens was analyzed ant then compensation using mold iteration process is followed to fabricate the high accuracy optic. Consequently, it is obvious that compensation of thermal deformation is critical and useful enough to be adopted to fabricate the lens by molding method.

Characterisation of Tensile Deformation through Infrared Imaging Technique

  • B. Venkataraman, Baldev Raj;Mukhophadyay, C.K.
    • Journal of the Korean Society for Nondestructive Testing
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    • v.22 no.6
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    • pp.609-620
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    • 2002
  • It is well known that during tensile testing, a part of the mechanical work done on the specimen is transformed into heat energy. However, the ultimate temperature rise and the rate of temperature rise is related to the nature of the material, conditions of the test and also to the deformation behaviour of the material during loading. The recent advances in infrared sensors and image/data processing techniques enable observation and quantitative analysis of the heat energy dissipated during such tensile tests. In this study, infrared imaging technique has been used to characterise the tensile deformation in AISI type 316 nuclear grade stainless steel. Apart from identifying the different stages during tensile deformation, the technique provided an accurate full-field temperature image by which the point and time of strain localization could be identified. The technique makes it possible to visualise the region of deformation and failure and also predict the exact region of fracture in advance. The effect of thermal gradients on plastic flow in the case of interrupted straining revealed that the interruption of strain and restraining at a lower strain rate not only delays the growth of the temperature gradient, but the temperature rise per unit strain decreases. The technique is a potential NDE tool that can be used for on-line detection of thermal gradients developed during extrusion and metal forming process which can be used for ensuring uniform distribution of plastic strain.