• Title/Summary/Keyword: identity play

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A Myostain-like Gene Expressed Highly in the Muscle Tissue of Chinese mitten crab, Eriocheir sinensis

  • Kim, Kyoung-Sun;Jeon, Jeong-Min;Kim, Hyun-Woo
    • Fisheries and Aquatic Sciences
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    • v.12 no.3
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    • pp.185-193
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    • 2009
  • A complete cDNA, which encodes for a myostatin-like protein (Es-MSTN), was isolated from the Chinese mitten crab, Eriocheir sinensis. Es-MSTN was composed of 2,397 nucleotides and the open reading frame (ORF) specified a protein containing 468 amino acids. Es-MSTN exhibited 32% amino acid sequence identity and 52% similarity to human myostatin. Multiple sequence alignment analysis indicated that Es-MSTN possessed the conserved proteolytic cleavage site (RXXR) for maturation of the protein and nine cysteine residues for disulfide bridges. Besides the conserved structural features, Es-MSTN also exhibits its unique characters; a longer N-terminal domain which is involved in protein folding and latent form of myostatin and absence of the cleavage site for BMP-1/tolloid family of metalloproteinase to activate mature myostatin. Phylogenetic analysis suggests that Es-MSTN showed the closely related to both vertebrate myostatin and GDF11. Es-MSTN is expressed highly in the claw muscle, leg muscle, thoracic muscle and heart, and moderately in the hindgut suggesting that Es-MSTN may play important roles in the muscle tissues. As homolog of mammalian myostatin and GDF11, Es-MSTN may be involved in development of muscular tissue and further study will help to produce high-quality seafood.

Proteome Analysis of Pigs Fed with Tissue Culture Medium Waste after Harvest of Korean Wild Ginseng (산삼배양액을 급여한 돼지에서 근육의 프로테옴 분석)

  • Seol, Jae-Won;Chae, Joon-Seok;Kang, Hyung-Sub;Kang, Chun-Seong;Ihn, Dong-Chul;Park, Sang-Youel
    • Journal of Veterinary Clinics
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    • v.28 no.1
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    • pp.75-80
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    • 2011
  • Proteomics is a useful approach to know protein expression, post-translational modification and protein function. We investigated the protein expression pattern and identity in pigs fed with the tissue culture medium waste after harvest of Korean wild ginseng (TCM-KWG) (Panax ginseng). Two groups (n = 30/group) of pigs were administered with 0 (control) and 16 ml/L (treatment) TCM-KWG through drinking water. After 4 weeks, we examined the protein expression pattern of longissimus dorsi muscle by Two-dimensional electrophoresis analysis. TCM-KWG treatment significantly increased two spot's density, and markedly reduced one spot's density in the muscles. We identified 3 proteins (heat shock protein 90-alpha, myosin binding protein and cofilin 2) by the ESI-MS/MS (Q-TOF2, Micromass). These results demonstrate that TCM-KWG treatment may play a protection role against physiological stress in pigs, like as increased heat shock protein 90-alpha.

The Development of Textile Design and The Manufacture of Cultural Merchandise by Using Lotus Flower Patterns(II) (연꽃 문양을 이용한 직물디자인 개발 및 문화상품 제작(II))

  • Jung, Jin-Soun
    • Fashion & Textile Research Journal
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    • v.6 no.4
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    • pp.421-426
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    • 2004
  • In an information-oriented and internationalized society of the future, the quality and the price of goods made by each country will be equalized. That eliminates competition. But the design and appearance of products is an important factor in international competition. Indeed, design symbolizes a country's culture visually, and it can show the cultural identity and originality of a nation in international society. And that will play an important part that can contribute to creating added value. It is necessary to revive our people's old lyrical stories which are far away from our memory, and we badly need design development to revive traditional cultural merchandise through visual modernization. In this study, I chose lotus as the subject material of textile design development. And my intention for this study is to reflect Korean traditional cultural value as much as I can, and to develop textile design of Korean images by adding modern scenes. Also, I intend to print them on fabric, and apply them to cultural merchandise including scarves and ties, by using digital textile printing systems. The reasons for doing so, are to create high added value, and to let other peoples of the world, know about our excellent culture.

Molecular Docking Studies of Wolbachia Endosymbiont of Brugia Malayi's Carbonic Anhydrase Using Coumarin-chromene Derivatives Towards Designing Anti-filarial Agents

  • Malathy, P.;Jagadeesan, G.;Gunasekaran, K.;Aravindhan, S.
    • Journal of Integrative Natural Science
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    • v.9 no.4
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    • pp.268-274
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    • 2016
  • Filariasis causing nematode Brugia malayi is shown to harbor wolbachia bacteria as symbionts. The sequenced genome of the wolbachia endosymbiont from B.malayi (wBm) offers an unprecedented opportunity to identify new wolbachia drug targets. Hence the enzyme carbonic anhydrase from wolbachia endosymbiont of Brugia malayi (wBm) which is responsible for the reversible interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa) is chosen as the drug target for filariasis. This enzyme is thought to play critical functions in bacteria by involving in various steps of their life cycle which are important for survival, The 3D structure of wBm carbonic anhydrase is predicted by selecting a suitable template using the similarity search tool, BLAST. The BLAST results shows a hexapeptide transferase family protein from Anaplasma phagocytophilum (PDB ID: 3IXC) having 77% similarity and 54% identity with wBm carbonic anhydrase. Hence the above enzyme is chosen as the template and the 3D structure of carbonic anhydrase is predicted by the tool Modeller9v7. Since the three dimensional structure of carbonic anhydrase from wolbachia endosymbiont of Brugia malayi has not yet solved, attempts were made to predict this protein. The predicted structure is validated and also molecular docking studies are carried out with the suitable inhibitors that have been solved experimentally.

A study on the work life of dental hygienists : for dental hygienists and dental hygiene students (치과위생사의 직업 수명에 관한 연구 : 치과위생사와 치위생(학)과 학생 대상으로)

  • Heo, Nam-Suk;Lee, Yu-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.2
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    • pp.209-220
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    • 2020
  • Objectives: Although dental hygienists have a high employment rate as professional workers, turnover and retirement rates are very high. This study analyzed the factors related to work life of dental hygienists to prepare an alternative for life extension. Methods: From August 1 to December 31, 2019, 224 dental hygienists and 446 dental hygiene students were examined. Results: The expected working years for dental hygienists were 10-14 years (25.4%) and over 31 years (22.4%) for dental hygiene students. The recognized working years for dental hygienists were 10-14 years (22.4%) and 20-24 years (26.0%) for dental hygiene students. Work values of dental hygienists and dental hygiene students averaged 3.85 and 3.86, respectively. Furthermore, the average motive for selecting a major in dental hygienists was 3.08 points and in dental hygiene students, 3.24 points. The average career identity of dental hygienists and dental hygiene students were 2.82 and 2.91 points, respectively. Conclusions: The perception difference between dental hygienists and dental hygiene students was compared, and the factors that could play a positive role in prolonging life were identified. Based on this study, further systematic comparative studies and preparation of alternatives for life extension are required.

A Study on the Spatial Presentation Strategies for Cafe as 'The Third Space' - Focused on the cafes located in regions where 'Street culture' was formed - ('제3의 공간'으로서 카페의 공간연출 전략에 관한 연구 - '길(street) 문화'가 형성된 지역을 중심으로 -)

  • Moon, Geun-Yi;Lyu, Ho-Chang
    • Korean Institute of Interior Design Journal
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    • v.22 no.5
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    • pp.68-77
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    • 2013
  • 'The Third space,' which is the concept that embraces sociological, spatial, and marketing concepts, refers to the place which is other than the home and the workplace and which is a comfortable frequented place where meditation, psychological relaxation, and social needs can be satisfied. 'The Third space' has the characteristics of comfort, openness, interactivity, playfulness, and diversity. In modern times, most of consumption spaces play the role of 'the Third space,' and the typical example is $Caf{\acute{e}}$. $Caf{\acute{e}}$ began from its origin with the characteristics of 'the Third space,' and recently it has become the complex cultural space of urban dwellers. $Caf{\acute{e}}$ as 'the Third space' has the characteristics of a healing space, communication space, personalized space, value-expressive space, culture and consumption space, nomad space. Such characteristics of $Caf{\acute{e}}$ are well represented in the cafes around the regions where 'street culture' has recently been formed. As examined through the examples, $Caf{\acute{e}}$ as 'the Third space' can be more strategically produced by establishing themes through storytelling, giving spatial identity through style creation, diversifying the sequence through complex space organization, and establishing interaction devices through experience elements.

Assuming the Role of a Racist and an Egalitarian Both Decreases Spontaneous Discriminatory Behavior

  • Park, Yeong Ock;Kim, Hyeon Jeong;Park, Sang Hee
    • Science of Emotion and Sensibility
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    • v.18 no.2
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    • pp.31-36
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    • 2015
  • This study employed the first-person shooter task(FPST: Correll, Park, Judd, & Wittenbrink, 2002) paradigm to examine racial bias toward Blacks in a population unrelated to the Black-White racial context. We tested whether having Korean participants play the role of a White police officer portrayed as nonracist (vs. racist) would attenuate the bias to shoot Black suspects. Participants were told that they would perform a police simulation task as a White police officer, who was described as racist or nonracist, or was presented without a description. They then performed the FPST. Although nonracist description lowered shooter bias, racist description weakened it even more, contrary to our prediction. The latter result is interpreted as due to activation of an egalitarian goal after reading about racism-related description, especially as the description was about someone who was to be incorporated to the self. Supporting this interpretation, a mediation analysis involving Racist and Control conditions revealed that the racist description was associated with stronger perception of the officer's racial bias, which in turn was correlated with weaker shooter bias.

The Impact of Brand Diversification on Firm Performance: A Study Restaurant Firms (외식기업의 브랜드 다각화가 수익성에 미치는 영향에 관한 연구)

  • Min, Ha-Na;Kim, In-Jung;Choi, Kyu-Wan
    • Journal of the Korean Society of Food Culture
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    • v.29 no.6
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    • pp.593-598
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    • 2014
  • Brands play a critical role as a core asset and the primary driver for corporate growth because of their power of identity and influence on customers' perceptions in restaurant industry. However, in spite of diverse and dynamically changing recent brand portfolio strategies of restaurants, a study on the effect of brand diversification on financial performance has been rarely conducted in the restaurant industry context. Considering competing viewpoints regarding diversification's influence on financial performance, the purpose of this study is, therefore, to examine the effect of brand diversification on firm performance of restaurants. The results indicated that brand diversification is positive effect to profitability. Brand diversification seems to be attractive and might be a reasonable growth strategy to expand market power by satisfying diverse consumer needs. Therefore, restaurant managers should be consider in implementing brand diversification strategy especially in dynamically changing trend of brand diversification in the current restaurant industry.

Identification and Characterization of New Copia-like Retrotransposon Osr1 in Rice

  • Lee, Yong-Hwan;Jwa, Nam-Soo;Park, Sook-Young;Park, Chan-Ho;Han, Seong-Sook
    • The Plant Pathology Journal
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    • v.19 no.1
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    • pp.57-63
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    • 2003
  • An insertion sequence identified as a solo long terminal repeat (LTR) of a new rice copia-like retrotransposon was detected in the ORE of the Pi-b gene from the rice cv. Nipponbare, and was designated as Osr1. Osr1 consists of a 6386 bp nucleotide sequence including 965 bp LTRs on both ends with an 82% nucleotide sequence identity to the wheat Tarl retrotransposon on reverse transcriptase. Nucleotide divergence was noted among the individual LTRs, as well as the coding region of Osr1. Various restriction fragment length polymorphism (RFLP) of LTR were detected in indica cultivars, whereas, only a few could be detected in the japonica cultivars. The population of Osr1 is lower in the wild-type rice compared with that in the domesticated cultivars. The insertion of LTR sequence in the h-b gene in the susceptible cultivar suggested that retro-tyansposon-mediated insertional mutation might play an important role in the resistance breakdown, as well as in the evolution of resistance genes in rice.

The management effect of TDC(Total Dental Care) internship program (일개 대학 치위생과 대학생들의 TDC(Total Dental Care) 인턴십 프로그램의 운영효과)

  • Cho, Min-Jung;Kim, Eun-Mi;Ha, Myung-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.2
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    • pp.147-154
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    • 2014
  • Objectives : The purpose of the study is to identify the efficiency of total dental care(TDC) internship program. Methods : Dental hygiene students participated in the total dental care(TDC) internship program for 4 weeks in dental clinics practice. A self-reported questionnaire was filled out from June to July in 2012. The questionnaire consisted of oral health condition and dental care services by the students, dentists, and dental hygienists after TDC internship program. Results : Satisfaction degree of the students was $3.92{\pm}0.68$ points. The patients satisfied with TDC internship program and it was helpful to their dental health care(4.0 points). There were significant changes in tooth brushing method, frequency and O'Leary plaque index. Satisfaction degree of the dentists was 4.09 points and that of the dental hygienists was 3.80 points. Conclusions : TDC internship program is very helpful for the students not only to play an outstanding role in their dental care activities after employment but also to establish the real identity of the dental hygienist.