• Clinical and Experimental Reproductive Medicine
• /
• v.43 no.2
• /
• pp.126-132
• /
• 2016

Objective: The purpose of this study was to identify useful clinical factors for the identification of patients with polycystic ovary syndrome (PCOS) who would benefit from in vitro maturation (IVM) treatment without exhibiting compromised pregnancy outcomes. Methods: A retrospective cohort study was performed of 186 consecutive patients with PCOS who underwent human chorionic gonadotropin-primed IVM treatment between March 2010 and March 2014. Only the first IVM cycle of each patient was included in this study. A retrospective case-control study was subsequently conducted to compare pregnancy outcomes between IVM and conventional in vitro fertilization (IVF) cycles. Results: Through logistic regression analyses, we arrived at the novel finding that serum $anti-M{\ddot{u}}llerian$ hormone (AMH) levels and the number of fertilized oocytes in IVM were independent predictive factors for live birth with unstandardized coefficients of 0.078 (95% confidence interval [CI], 1.005-1.164; p=0.037) and 0.113 (95% CI, 1.038-1.208; p=0.003), respectively. Furthermore, these two parameters were able to discriminate patients who experienced live births from non-pregnant IVM patients using cut-off levels of 8.5 ng/mL and five fertilized oocytes, respectively. A subsequent retrospective case-control study of patients with PCOS who had serum AMH levels ${\geq}8.5ng/mL$ showed that IVM had pregnancy outcomes comparable to conventional IVF, and that no cases of ovarian hyperstimulation syndrome were observed. Conclusion: Serum AMH levels are a useful factor for predicting pregnancy outcomes in PCOS patients before the beginning of an IVM cycle. IVM may be an alternative to conventional IVF for PCOS patients if the patients are properly selected according to predictive factors such as serum AMH levels.

• Korean Journal of Microbiology
• /
• v.46 no.2
• /
• pp.127-133
• /
• 2010

The purpose of this work was to investigate the antibacterial activity derived from a lactic acid bacterium, Lactococcus lactis HK-9, isolated from the feces of a 2-day newborn infant. We characterized the physiological and biochemical properties of this strain. Both the BIOLOG system and phylogenetic analysis using 16S rRNA sequencing were utilized for identification, and the strain was assigned to the Lactococcus lactis species, designated as L. lactis HK-9, and registered in GenBank as [GU936712]. We monitored growth rate, production of lactic acid and acetic acid as metabolites, and pH during growth. The maximum concentrations of lactic acid and acetic acid reached 495.6 mM and 104.3 mM, respectively, and the initial pH of the cultures decreased from 7.0 to 4.1 after incubating for 60 h. HPLC was used to confirm the production of lactic acid and acetic acid. Significant antibacterial activity of the concentrated supernatant was demonstrated against Gram-positive (e.g., Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes, MRSA) and Gram-negative (e.g., Escherichia coli, Salmonella enteritidis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella sonnei) bacteria by the plate diffusion method. The antibacterial activity was sensitive to protease, and the molecular weight of the presumed bacteriocin molecule was estimated to be about 4 kDa by tricine-SDS-PAGE.

• Journal of Satellite, Information and Communications
• /
• v.2 no.1
• /
• pp.35-40
• /
• 2007

COSPAS-SARSAT is the search and rescue system for providing a distress alarm and a position identification using an international satellite and ground facilities. Aviators, mariners and land users worldwide are equipped with COSPAS-SARSAT distress beacons, which could help save their in emergency situations anywhere in the world. As the existing COSPAS-SARSAT system is generally operated by LEO(Low-altitude Earth Orbit) Satellite System, the time from the distress beacon to the rescue is more than 1 hour with average and the accuracy of the distress location is about 5 Km. Therefore, in order to overcome this problem, the development for the next generation SAR(search and rescue) system which uses the MEO(middle-altitude Earth Orbit) satellites is going on the Galileo project. EU is developing this project for the full operation capability in 2011, and this project will have SAR payloads and support to the Search and Rescue service-herein called SAR/Galileo. SAR/Galileo will have the performance of a few meter accuracy, within 10 minutes to rescue from reception of distress messages, and Return Link Service(from the SAR operator to the distress emitting beacon), thereby facilitating more efficient rescue operations and helping to reduce the rate of false alerts. As the disaster is larger every year, the ground station, MEOLUT for next generation ASR/Galileo is urgently needed for the lifesaving for the larger disaster, the research for beacon and the ground station such as MEOLUT for introducing the next generation SAR/Galileo in Korea is very timely and is important. This paper presents the procedures and the strategies for the participation, the area to develop reasonably, and the propulsion organization for developing the SAR/Galileo ground system in Korea.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.35 no.2
• /
• pp.196-200
• /
• 2002

In order to identify the feeding stimulants for flatfish, the feeding tests were conducted using some diets added the amino acids, nucleotides, betaine and TU and acid hydrolysates to basal diet formula, respectively, The feeding stimulant activities and synergistic effects of those compounds were evaluated by a bioassay method. The KH, a kind of acid hydrolysate, possessed a remarkable feeding stimulant activity. It's stimulant activities were increased up to the concentration of $1.05\%$ (w/v), and were independent of pH. The formulation of KH and glycine had a most synergistic effect, The feeding rate of diet with feeding stimulation was 1,4 fold than that of diet without one. The costs for optimum formulation of feeding stimulants were cheaper than some additives in diets. It suggest that the results can practically used in preparation of diet containing feeding stimulant effects for flatfish.

• Tuberculosis and Respiratory Diseases
• /
• v.43 no.6
• /
• pp.894-902
• /
• 1996

Background : Tumor angiogenesis is the growth of new vessels toward and within tumor. It has been demonstrated that the growth of tumor beyond a certain size requires angiogenesis and it is closely involved in tumor progression and metastasis. The finding that intensity of neovascularization correlates independently with metastasis may lead to identification of patients in whom radical surgery should be supplemented by systemic treatment. Method : We have collected paraffin blocks of bronchoscopic biopsy of patients with non-small cell lung cancer. We highlighted the vessel by staining endothelial cell with JC70 monoclonal antibody(to CD31) immunohistochemically and counted microvessels under 200 X field using light microscopy. Results : 1) The mean microvessel count was $32.7{\pm}20.8$ (9-96) in total 29 cases. 2) There were no correlations between microvessel counts and pathologic cell type, T staging, node melastasis(N) and hematogenous metastasis(M) (p>0.05). 3) The median follow-up duration was 15 months(2-46) and there was no correlation between the microvessel counts and survival rate of lung cancer patients (p>0.05). Conclusion : Tumor angiogenesis seems to be an important prognostic factor suggesting the probability of metastasis. But the microvessel count in the bronchoscopic biopsy specimen was inadequate and very limited. There has been no data about angiogenesis of lung cancer in korea yet So the study of tumor angiogenesis using resected lung tumor specimen would be demanded.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.17 no.3
• /
• pp.380-389
• /
• 2007

In Korea, undoubtedly, the cancer is one of the most common reasons of death, and hepatoma is the second highest fatal cancer regardless of the gender only next to the stomach cancer In the middle and prime-aged between 40 and 60 years, the incidence of hepatoma is the highest in the world, and the death rate due to hepatoma is the highest among OECD countries. In this paper, we propose a novel method for automatic identification of hepatoma from a contrast enhanced CT images, which is used in an expert system that helps medical specialists. First, consecutive $40{\sim}50$ contrail enhanced CT images are photographed by every 5mm from the upper part of the chest, and using position information on the rib, we classify the internal area including only internal organs and the external one that consists of the rib, subcutaneous fat layers, and the background from the CT images. Then, the region of the liver is extracted from the classified internal area by using information on the intensity, the distribution of brightness, and using the regions extracted from consecutive images, we restore information on the 5 mm space occurred between the consecutive two slides tty applying a shape-based interpolation method. Lastly, using the characteristics such as the brightness and the morphology, we are able to extract the regions of hepatoma. The expert system based on our method is sufficiently competitive when it is compared with the diagnoses by specialists in the diagnostic radiology.

• Journal of Information Technology and Architecture
• /
• v.10 no.1
• /
• pp.101-111
• /
• 2013

Internet traffic volume has been increasing rapidly due to popularization of various smart devices and Internet development. In particular, HTTP-based traffic volume of smart devices is increasing rapidly in addition to desktop traffic volume. The increased mobile traffic can cause serious problems such as network overload, web security, and QoS. In order to solve these problems of the Internet overload and security, it is necessary to accurately detect applications. Traditionally, well-known port based method is utilized in traffic classification. However, this method shows low accuracy since P2P applications exploit a TCP/80 port, which is used for the HTTP protocol; to avoid firewall or IDS. Signature-based method is proposed to solve the lower accuracy problem. This method shows higher analysis rate but it has overhead of signature generation. Also, previous signature-based study only analyzes applications in HTTP protocol-level not application-level. That is, it is difficult to identify application name. Therefore, previous study only performs protocol-level analysis. In this paper, we propose a signature generation method to classify HTTP-based traffics in application-level using the characteristics of typical semi HTTP header. By applying our proposed method to campus network traffic, we validate feasibility of our method.

• Korean journal of applied entomology
• /
• v.23 no.2 s.59
• /
• pp.82-88
• /
• 1984

Fruit rot and blister canker, a disease of apple occurring severely in Korea has been studied for correct identification of the syndrome In fruit and apple trees. Among the fungi isolated from blister cankers, rough barks or fruits showing rotting of 7 different host species were Botryosphaeria berengeriana (pycnidial stage. Dethiorella mali), Penicillium expansum and Alternaria sp. from apple rots and Phomopsis sp. from pear fruit rots. The most dominant isolates were B. berengeriana. Ten isolates of D. mali were grouped in to two conidial types based up mycelial growth rate, growth habits and mycelial coloration on PDA. None of 10 isolates was chromogenic. Pycnidia in apple stems, stromatic, dark brown, globose or subglobose and the measuring were $103.5-287.5{\mu}\times92.0-287.5\mu$. The pycnidia contained hyaline, nonseptate, fusiform conidia. The sizes of pycnidiospore of isolates obtained from apple twig were $4.3-7.2{\mu}\times20.0-31.5{\mu}(average\;5.9\times25.4\mu)$. Some conidia of this fungus from apple, pear, peach and ornamental cherry showed 1-,2-,3-septate before or during germination. Microconidia were observed in pycnidia on PDA and fruit lesion of inoculated host. Symptoms on leaves and fruits were contoured brown spots when inoculated. Wart-like protuberance were formed on the surface of apple and pear. Canker appeared on branches of peach and ornamental cherry inoculated.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.23 no.1
• /
• pp.61-71
• /
• 2010

The attributes related to the health condition of RC deck slabs are analyzed to help us identify and rate the safety level of the bridges in this study. According to the related reports the state assessment for the outward aspects of bridges is the important and critical part for rating the overall structural safety. In this respect, the careful identification for the various state attributes make the field inspection and structural diagnosis very effective. This study analyzes the influence of the state attributes on evaluation classes and the relationship of them by the inductive reasoning, which raise the understanding and performance for evaluation work, and support the logical approach for the state assessment. ID3 algorithm applied to the case set which is constructed from the field reports indicates the main attributes and the precedence governing the assessment, and derives the decision hierarchy for the state assessment.

• Journal of Korea Water Resources Association
• /
• v.53 no.11
• /
• pp.1015-1024
• /
• 2020

Recently, water pollution accidents have continued to occur in pipelines such as red water Incheon and Seoul. In order to recognize this water quality problem, it is necessary to install a water quality sensor in an appropriate location and measure it in advance to detect or block the water supply to the water faucet of the shelter. However, there are limitations, such as maintenance costs, to installing multiple water meters in all pipelines. Therefore, this study proposed a methodology for determining and prioritizing the installation location of flow-based water quality sensor for the recognition of water quality problems in pipelines. We applied the proposed procedure to the pipe break scenario. The results of the determination of the location of the water quality sensor were presented by applying it to the pipe network that actually operates the emergency pipe in Korea. The result of the decision showed that in the event of abnormal situation caused by the destruction of individual pipes, the flow rate of the pipes around the aqueduct and the tank may change rapidly, resulting in water quality accidents caused by turbidity. In the future, it is expected that the water quality monitoring point selection method, such as establishing an external pipe operation plan for pipe cleaning, will utilize the procedure for determining the location of the water quality sensor according to the velocity.