• Title/Summary/Keyword: identification rate

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Prevalence and Survival Patterns of Patients with Bone Metastasis from Common Cancers in Thailand

  • Phanphaisarn, Areerak;Patumanond, Jayantorn;Settakorn, Jongkolnee;Chaiyawat, Parunya;Klangjorhor, Jeerawan;Pruksakorn, Dumnoensun
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.9
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    • pp.4335-4340
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    • 2016
  • Background: Bone metastasis is a single condition but presents with various patterns and severities. Skeletal-related events (SREs) deteriorate overall performance status and reduce quality of life. However, guidelines for early detection and management are limited. This study includes a survey of the prevalence of bone metastasis in cases with common cancers in Thailand as well as a focus on survival patterns and SREs. Materials and Methods: A retrospective cohort analysis was conducted using a database of the Chiang Mai Cancer Registry and the Musculoskeletal Tumor Registry of the OLARN Center, Chiang Mai University. The prevalence of bone metastasis from each type of primary cancer was noted and time-to-event analysis was performed to estimate cancer survival rates after bone metastasis. Results: There were 29,447 cases of the ten most common cancers in Thailand, accounting for 82.2% of the entire cancer registry entries during the study period. Among those cases, there were 2,263 with bone metastases, accounting for 7.68% of entries. Bone metastasis from lung, liver, breast, cervix and prostate are common in the Thai population, accounting for 83.4% of all positive cases. The median survival time of all was 6 months. Of the bone metastases, 48.9% required therapeutic intervention, including treatment of spinal cord and nerve root compression, pathological fractures, and bone pain. Conclusions: The frequency of the top five types of bone metastasis in Thailand were different from the frequencies in other countries, but corresponded to the relative prevalence of the cancers in Thailand and osteophilic properties of each cancer. The results of this study support the establishment of country specific guidelines for primary cancer identification with skeletal lesions of unknown origin. In addition, further clinical studies of the top five bone metastases should be performed to develop guidelines for optimal patient management during palliative care.

An Epidemiological survey on the Taeniasis in Seoul city and Cheju Do, Korea (제주도(濟州道) 및 서울 일부지역(一部地域)에 있어서의 조충(條虫) 감염율(感染率)과 유(有), 무구조충(無鉤條虫) 감염상황(感染狀況)에 관한 조사(調査))

  • Joo, Kyung-Hwan;Seong, Dae-Rim;Cho, You-Jung
    • Journal of agricultural medicine and community health
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    • v.10 no.1
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    • pp.26-35
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    • 1985
  • The present study was undertaken to evaluate the prevalence rate of Taenia species infection and distribution of taeniasis caused by Taenia solium among Koreans in Seoul and Cheju Do In Korea during the period from August to December 1984. A total of 4,256 stool specimens from the students of Mapo Ku and 360 stool specimens from the inhabitants of Guro-Ku in Seoul was collected and examined by cellophane thick smear technique. On the other hand 1,015 stool specimens from the students of Jocheon Myun and 265 specimens from the students of Jocheon Myun and 265 specimens from the inhabitants of Aeweol Myun and Gujwa Myun in Cheju Do were also examined. The results were summarized as follows ; Four (0.1%) out of 4.256 students were positive and 2 (0.6%) out of 360 inhabitants in Seoul were positive (Table 1, 2). Positive rates of taeniasis in Cheju Do were 1.7% (17) out of 1,015 students and 12.5% (33) out of 5 villagers (Table 3, 4). In order to observe the distribution of Taenia solium infection, the scolex or a part of Taenia spp. were collected from the stool of positive cases by anthelmintic treatment. For the species identification, expelled proglottides were examined microscopically by the number of branches of the uterus, presence of vaginal sphincter or the accessory ovarian lobe etc. Three cases were infected with Taenia solium among 6 egg positive cases in Seoul. But only 1 case was infected with Taenia solium out of 7 students taking anthelmintics voluntarily by recommendation of Korean Association for Parasite Eradication (KAFPE). On the other hand, among 32 cases of egg positive cases of this study and 26 cases of KAFPE in Cheju Do, 13 cases (22.4%) were infected with Taenia solium. But 13 cases who were not examined and complained expulsion of proglottides in their stool were infected with Taenia saginata (Table 5). Among 62 persons infected with Taenia saginata, only 4 cases did not know their infection of this worm. Rut in 17 cases with Taenia solium, 7 persons did not know their infection until stool examinations were performed (Table 6).

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A Review on Efficient Operation Technology of Compost Depot (퇴비사의 효율적인 운영기술에 대한 고찰)

  • Yang, Il-Seung;Ji, Min-Kyu;Jeon, Byong-Hun
    • Clean Technology
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    • v.23 no.4
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    • pp.345-356
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    • 2017
  • The composting is a biological process that converts organic matter into useful resources such as fertilizers. It is a continuous transition of microbial communities to adapt changes in organic matter and environmental conditions (carbonation rate, temperature, humidity, oxygen supply, pH, etc.). Most of the composting plants are located in the proximity of the residential areas. It is a general scenario where government authorities receive complaints from the local residents due to release of odor from the composting, and has become a social problem in Korea. Identification of dominant microorganisms, understanding change in microbial communities and augmentation of specific microorganism for composting is vital to enhance the efficiency of composting, quality of the compost produced, and reduction of odor. In this paper, we suggest the optimum operation conditions and methods for compost depot to reduce odor generation. The selection of the appropriate microorganisms and their rapid increase in population are effective to promote composting. The optimal growth conditions of bacteria such as aeration (oxygen), temperature, and humidity were standardized to maximize composting through microbial degradation. The use of porous minerals and moisture control has significantly improved odor removal. Recent technologies to reduce odor from the composting environment and improved composting processes are also presented.

Development of glufosinate-tolerant GMO detection markers for food safety management (식품안전관리를 위한 제초제 glufosinate 특이적 GM 작물 검출마커 개발)

  • Song, Minji;Qin, Yang;Cho, Younsung;Park, TaeSung;Lim, Myung-Ho
    • Korean Journal of Food Science and Technology
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    • v.52 no.1
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    • pp.40-45
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    • 2020
  • Over 500 genetically modified organisms (GMOs) have been developed since 1996, of which nearly 44% have glufosinate herbicide-tolerant traits. Identification of specific markers that can be used to identify herbicide-tolerant traits is challenging as the DNA sequences of the gene(s) of a trait are highly variable depending on the origin of the gene(s), plant species, and developers. To develop specific PCR marker(s) for the detection of the glufosinate-tolerance trait, DNA sequences of several pat or bar genes were compared and a diverse combination of PCR primer sets were examined using certified reference materials or transgenic plants. Based on both the qualitative and quantitative PCR tests, a primer set specific for pat and non-specific for bar was developed. Additionally, a set of markers that can detect both pat and bar was developed, and the quantitative PCR data indicated that the primer pairs were sensitive enough to detect 0.1% of the mixed seed content rate.

Study on the Distribution of Vibrio parahaemolyticus along Cheju Coast (제주연안해역의 Vibrio parahaemolyticus 분포에 관한 연구)

  • Song, Min-Kyoung;Kim, Man-Chul;Heo, Moon-Soo
    • Korean Journal of Environmental Biology
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    • v.25 no.1
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    • pp.34-41
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    • 2007
  • A study on the distribution of V. parahaemolyticus among sea water, sea mud, and marine products in Hwabuk, Samyang, Daepo, Jungmun, Pyoson, Anduk, Aewol, and Gwakji on the coastal area of Jeju island was conducted from January to December in 2002. The 2,880 total specimens of 960 sea waters, 960 sea mud, 960 marine products were collected and studied for the rate of isolation of V. parahaemolyticus, and biochemical, serological and antibiotic sensitivity tests were performed. A total of 417 strains of V. parahaemolyticus were isolated and identified from 2,880 total specimens. In the test of biochemical properties, 100 of V. parahaemolyticus isolates in the presence of 0.85% NaCl were positive in the utilization of lysine, ornithine, indole, glucose, and mannitol, and negative in the utilization of ONPG, arginine, sodium citrate, urea, tryptophane, inositol, sorbitol, rhamnose, sucrose, and melibiose, $H_2S$ production and VP reaction, while positive or negative in gelatin liquefaction and utilization of amygdalin or arabinose. The isolation rates to the specimen were 161 strains (16.8%) from 960 of sea waters, 137 strains (14.3%) from 960 of sea mud, and 119 strains (12.4%) from 960 of marine products. The isolation rates of V. parahaemolyticus from 8 coastal areas were 14.4% (52/360) in Hwabuk area, 15.3% (55/360) in Samyang area, 13.6% (49/360) in Daepo area, 18.3% (66/360) Jungmun area, 13.1% (47/360) in Pyosun area, 16.4% (59/360) in Anduk area, 12.5% (45/360) in Aewol area and 12.2% (44/360) in Gwakji area, respectively. The distribution of 417 V. parahaemolyticus, isolates was high at Jungmun with 18.3% (66/360), and from sea water with 16.8% (161/960).

Isolation and identification of Cryptosporidium from various animals in Korea I. Prevalence of Cyuptosporidium in various animals (한국산 동물로부터 크립토스포리디움의 분리 및 동정 I . 각종 동물의 크립토스포리더움 감염상황)

  • Lee, Jae-Gu;Seo, Yeong-Seok;Park, Bae-Geun
    • Parasites, Hosts and Diseases
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    • v.29 no.2
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    • pp.139-148
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    • 1991
  • Cryptosporidium, a coccidian protozoa, commonly causes a self-limiting diarrheal illness in humans and animals. Fecal samples from various animals in Chonbuk district were observed using Sheather's aoatation technique, Kinyoun's modified acid-fast staining, and osmic acid pre-fixed Giemsa staining. The oocysts were detected in 74 cages(29.6%) out of 250 cages of mature mice, 26 (13.3%) out of 195 mature house rats, 75 (15.0%) out of 4-week-old 500 fowls, 98(19.9%) out of 6 to 8-month-old 500 pigs, and 111(22,2%) out of 2 to 5-year-old 500 dairy cattle, respectively. The degree of prevalence was slight in general, but actual prevalence was higher than infection rate because the detection rates were higher in repeated-preparation examinations in comparison to the first examination. Meanwhile, large and small types of oocysts were detected from mice, house rats, pigs, and cattle, and midium type from fowls.

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Isolation and Identification of Pentachlorophenol-degrading Bacteria (Pentachlorophenol을 분해하는 세균의 분리와 동정)

  • Park, Young-Doo;Eum, Jin-Seong
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.4
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    • pp.261-265
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    • 2000
  • To develope the enhanced bacterial strains capable of biodegradation for various chlorinated aromatic compounds, 100 bacterial strains were isolated from soil samples of suburbs of Taejon, Cheongju, and Jeonju by the enrichment culture. These strains can degrade pentachlorophenol (PCP) which is a kind of wood preservatives. Nineteen strains of the isolates were selected by fast colony-forming rate on solid minimal media containing PCP as an only source of carbon and energy. These strains were identified to genus level. Fifteen strains were identified as Pseudomonas, 1 strain as Acinetobacter and 3 strains were not. Genus Alcaligenes strains were not found among them. Pseudomonas sp. MU135. MU139, MU163 and MU 184 were able to degrade for 4 kinds of chlorinated compounds, PCP, 2,4-D, MCPA and 3CB. Pseudomonas sp. If was observed that MU139 exhibits the highest degradability in liquid minimal media at 72 hours after inoculation. Pseudomoans sp. MU147, MU177, MU184 and MU192 also degraded the compounds at higher rates. As the results, Pseudomonas sp. MU139 and unidentified strain MU184 had biodegrability for broad range of chlorinated compounds and higher rates of degradation for PCP.

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Clinical Features of Deep Neck Infections and Predisposing Factors for Mediastinal Extension

  • Kang, Shin-Kwang;Lee, Seok-Kee;Oh, Hyun-Kong;Kang, Min-Woong;Na, Myung-Hoon;Yu, Jae-Hyeon;Koo, Bon-Seok;Lim, Seung-Pyung
    • Journal of Chest Surgery
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    • v.45 no.3
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    • pp.171-176
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    • 2012
  • Background: Deep neck infections (DNI) can originate from infection in the potential spaces and fascial planes of the neck. DNI can be managed without surgery, but there are cases that need surgical treatment, especially in the case of mediastinal involvement. The aim of this study is to identify clinical features of DNI and analyze the predisposing factors for mediastinal extension. Materials and Methods: We reviewed medical records of 56 patients suffering from DNI who underwent cervical drainage only (CD group) and those who underwent cervical drainage combined with mediastinal drainage for descending necrotizing mediastinitis (MD group) from August 2003 to May 2009 and compared the clinical features of each group and the predisposing factors for mediastinal extension. Results: Forty-four out of the 56 patients underwent cervical drainage only (79%) and 12 patients needed both cervical and mediastinal drainage (21%). There were no differences between the two groups in gender (p=0.28), but the MD group was older than the CD group (CD group, $44.2{\pm}23.2$ years; MD group, $55.6{\pm}12.1$ years; p=0.03). The MD group had a higher rate of co-morbidity than the CD group (p=0.04). The CD group involved more than two spaces in 14 cases (32%) and retropharyngeal involvement in 12 cases (27%). The MD group involved more than two spaces in 11 cases (92%) and retropharyngeal involvement in 12 cases (100%). Organism identification took place in 28 cases (64%) of the CD group and 3 cases of (25%) the MD group (p=0.02). The mean hospital stay of the CD group was $21.5{\pm}15.9$ days and that of the MD group was $41.4{\pm}29.4$ days (p=0.04). Conclusion: The predisposing factors of mediastinal extension in DNI were older age, involvement of two or more spaces, especially including the retropharyngeal space, and more comorbidities. The MD group had a longer hospital stay, higher mortality, and more failure to identify causative organisms of causative organisms than the CD group.

A Descriptive Study on the Tuberculosis Mortality in a Tuberculosis-Centered Hospital (한 결핵전문병원의 입원 결핵환자 사망에 대한 기술통계학적 고찰)

  • Kim, Soo-Young;Byun, Joo-Nam;Choi, Jin-Su
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.5
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    • pp.595-601
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    • 1993
  • Background: Today, tuberculosis continues as an important cause of death in Korea despite the effective treatment and prevention. So we have studied charicteristic distribution of death by pulmonary tuberculosis through epidemiologic survey. Subjects and Method: The mortality data were obtained from 684 pulmonary tuberculosis cases who died in a tuberculosis-centered hospital in Seoul during the period of 5 years from 1986 to 1990. In order to estimate the distribution of death by tuberculosis, t-test and $x^2$-text were performed on the data. Results: 1) 19.9% of patients died among the total 3,441 hospitalized pulmonary tuberculosis cases during 5 years. 2) In distribution of sex and age, male death occupies 81% of total death. Significantly high proportions of younger female death (under 40 years-old) were also observed. 3) In terms of medical security status, medical assistance group occupies 42.3% of medical insurance group while the non-security group also occupies 11.8% of total death. 4) Treatment interruption was observed in 78% of total death. Conclusion: Special attention should be given to the identification, management and follow up of high risk group in nationwide tuberculosis control program.

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Creation and Elaboration of Problem Space Depending on Students' Attitudes toward the Task and Thinking Skills (학생의 과제에 대한 태도와 사고력에 따른 문제공간의 형성과 정교화)

  • Kim, Kyung-Jin
    • Journal of the Korean earth science society
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    • v.30 no.1
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    • pp.141-151
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    • 2009
  • Inquiry has been emphasized in science classrooms, but the problems shown in the inquiry are somewhat different with ones that students usually meet and experience in everyday life. The purpose of this study is to investigate how attitudes toward the task and thinking skills affect students' problem solving process, especially, the way of creating a problem space and elaborating problem solving strategies when they have little schema. The difference in students' problem solving strategies of Lego Robotics class, one of the summer programs for $4^{th}-6^{th}$ grade gifted students, which is new to them, was investigated. The results are as follows: (1) The difference in attitudes toward the task, or selection and identification of the missions, and the perception of operators, affected creating a different problem space. (2) Different level of thinking skills, or analytical and flexible thinking, efficient elaborative skill, and application of schema affected a different level of elaboration of the problem space and resulted in asuccess rate of problem solving. (3) Different initial problem space resulted in different problem solving strategies. But without thinking skills, students could not elaborate problem solving strategies efficiently. Several instructional recommendations to promote scientific inquiry were suggested based on the results.