• Title/Summary/Keyword: iSQC

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Clinicopathologic Characteristics of Recurrence after Curative-intent Surgical Therapy of Non-small Cell Lung Cancer (근치적 수술 후 재발한 I, II 병기 비소세포폐암의 임상양상 및 조직학적 유형의 차이 비교)

  • Song, Sung-Heon;Sohn, Jang-Won;Kwak, Hyun-Jung;Kim, Sa-Il;Lee, Seung-Ho;Kim, Sang-Heon;Kim, Tae-Hyung;Yoon, Ho-Joo;Shin, Dong-Ho;Park, Sung-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.4
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    • pp.330-337
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    • 2011
  • Background: The clinicopathologic characteristics of patients with non-small cell lung cancer (NSCLC) have been changing. Recently, Positron emission tomography-computed tomography (PET-CT) has usually been used for diagnosis, follow-up to treatment and surveillance of NSCLC. We studied the pattern of recurrence and prognosis in patients who underwent complete resection for NSCLC according to histologic subtype. Methods: All patients who underwent complete resection for pathological stage I or II NSCLC between January 2005 and June 2009 were identified and clinical records were reviewed retrospectively, especially the histologic subtype. Results: Recurrences were identified in 50 of 112 patients who had complete resection of an NSCLC. Sites of recurrence were locoregional in 15 (30%), locoregional and distant in 20 (40%), and distant in 15 (30%). Also, sites of recurrence were intra-thoracic in 29 (58%), extrathoracic and intra-thoracic recurrence in 15 (30%), and extrathoracic in 6 (12%). In locoregional recurrence, there was 37% recurrence for non-squamous cell carcinoma (non-SQC) and 25% for squamous cell carcinoma (SQC). In distant recurrence, there was 39% recurrence for non-SQC and 18% for SQC. Locoregional recurrence in the bronchial stump was more common in SQC than non-SQC (14% vs. 45%, p=0.025). Prognosis of recurrence was not influenced by histologic subtype and the recurrence-free survival curve showed that the non-SQC group did not differ from the SQC group according to stage. Conclusion: The prognosis for recurrence does not seem to be influenced by histologic types, but locoregional recurrence in the bronchial stump seems to be more common in SQC than non-SQC in completely resected stage I and II NSCLC.

Solvent-localized in-situ NMR Monitoring by Intermolecular Single-quantum Coherence Study

  • Cha, Jin Wook;Park, Sunghyouk
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.4
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    • pp.96-103
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    • 2020
  • A new NMR method to monitor solvent-localized NMR signals in the two-phase liquid system is suggested. This method based on intermolecular single-quantum coherence (iSQC). Here, we exploited the feature of the local action of distant dipolar field (DDF) effect in order to filter out specific NMR signals dissolved in different solvents. This solvent specific iSQC spectroscopy was carried out on a model two-phase liquid system (D-glucose in water/palmitic acid in chloroform), and showed solvent-localized NMR signals. We believe our approaches might be useful in metabolic analysis such as two-phase liquid extraction scheme for labile chemical species.

Robust Transfer Alignment Method based on Krein Space (크레인 공간에 기반한 강인한 전달정렬 기법)

  • Sung-Hye Choe;Ki-Young Park;Hyoung-Min Kim;Cheol-Kwan Yang
    • Journal of Advanced Navigation Technology
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    • v.25 no.6
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    • pp.543-549
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    • 2021
  • In this paper, a robust transfer alignment method is proposed for a strapdown inertial navigation system(SDINS) with norm-bounded parametric uncertainties. The uncertainties are described by the energy bound constraint, i.e., sum quadratic constraint(SQC). It is shown that the SQC can be coverted into an indefinite quadratic cost function in the Krein space. Krein space Kalman filter is designed by modifying the measurement matrix and the variance of measurement noises in the conventional Kalman filter. Since the proposed Krein space Kalman filter has the same recursive structure as a conventional Kalman filter, the proposed filter can easily be designed. The simulation results show that the proposed filter achieves robustness against measurement time delay and high dynamic environment of the vehicle.