• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2523-2527
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• 2014

Background: Serum thyroglobulin detection plays an essential role during the follow-up of thyroid cancer patients treated with total/near total thyroidectomy and radioiodine ablation. The aim of this retrospective study was to evaluate the relationship between stimulated serum thyroglobulin (Tg) level at the time of high dose $^{131}I$ ablation and risk of recurrence, using a three-level classification in patients with differentiated thyroid cancer (DTC) according to the ATA guidelines. Also we investigated the relationship between postoperative stimulated Tg at the time of ablation and DxWBS results at 8-10 months thereafter. Materials and Methods: Patients with radioiodine accumulation were regarded as scan positive (scan+). If there was no relevant pathological radioiodine accumulation or minimal local accumulation in the thyroid bed region, this were regarded as scan negative (scan-) at the time of DxWBS. We classified patients in 3 groups as low, intermediate and high risk group for assessment of risk of recurrence according to the revised ATA guidelines. Also, we divided patients into 3 groups based on the stimulated serum Tg levels at the time of $^{131}I$ ablation therapy. Groups 1-3 consisted of patients who had Tg levels of ${\leq}2ng/ml$, 2-10 ng/ml, and ${\geq}10ng/ml$, respectively. Results: A total of 221 consecutive patients were included. In the high risk group according to the ATA guideline, while 45.5% of demonstrated Scan(+) Tg(+), 27.3% of patients demonstrated Scan(-) Tg(-); in the intermediate group, the figures were 2.3% and 90.0% while in the low risk group, they were 0.6% and 96.4%. In 9 of 11 patients with metastases (81.8%), stimulated serum Tg level at the time of radioiodine ablation therapy was over 10, however in 1 patient (9.1%) it was <2ng/mL and in one patient it was 2-10ng/mL (p=0.005). Aggressive subtypes of DTC were found in 8 of 221 patients and serum Tg levels were ${\leq}2ng/ml$ in 4 of these 8. Conclusions: We conclude that TSH-stimulated serum thyroglobulin level at the time of ablation may not determine risk of recurrence. Therefore, DxWBS should be performed at 8-12 months after ablation therapy.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.5
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• pp.400-404
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• 2009

Native Command Queueing is a technology to maximize throughput of disk system by reordering requests in its command queue. Recent S-ATA 2 standard specifies a protocol for the purpose of dealing with NCQ feature, making most vendors implementing it in their disk devices. However, the new feature, NCQ, may lead to information gap between OS and disk drive. 05 considers that disk will service I/O requests in the order as OS has dispatched. Unfortunately, it isn't true any more since NCQ would simply ignore the policy of OS and reorder the sequence OS has expected. Let us define the term as expectation-discord. Due to the discord, serious performance anomalies or starvation of requests may occur in I/O subsystem. In this paper, we confirm that the expectation-discord actually brings about starvation of requests. We propose a solution to settle it. Our solution is very simple, effective, cheap(not requiring any hardware modification) and portable across various OS. Experimental results show that our solution can balance throughput and response time very well.

• Journal of the Microelectronics and Packaging Society
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• v.20 no.4
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• pp.69-74
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• 2013

In this paper, the impact of integrating large number of I/O (Input-Output) and Core power Delivery Network (PDN) on a 6 layers Flip-Chip Ball Grid Array (FCBGA) package is investigated. The impact of core induced supply noise on high-speed I/O interfaces, and high-speed I/O interface's supply noise coupling to adjacent high-speed I/O interfaces' jitter impact are studied. Concurrent stress validation software is used to induce SSO noise on each individual I/O interfaces; and at the same time; periodic noise is introduced from Core PDN into the I/O PDN domain. In order to have the maximum coupling impact, a prototype package is designed to merge the I/O and Core PDN as one while impact on jitter on each I/O interfaces are investigated. In order to understand the impact of the Core to I/O and I/O to I/O noise, the on-die noise measurements were measured and results were compared with the original PDN where each I/O and Core PDN are standalone and isolated are used as a benchmark.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04a
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• pp.127-129
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• 2003

현재 데이터의 양은 인터넷 관련 비즈니스/전자상거래 등 인터넷 프로토콜(IP) 네트워크를 이용한 저장 장치의 데이터 증가를 가져오게 되었다. 본 논문에서는 펜티엄 프로세서, 고속 이더넷 IDE RAID 시스템 (IDE RAID Controller와 IDE 디스크로 구성)과 iSCSI(Internet Small Computer System Interface) 프로토콜을 이용하여 저렴한 비용으로 비교적 우수한 성능의 리눅스 기반의 저장장치 시스템을 설계 구현하였다. 또한 저장장치 시스템의 벤치마크 프로그램인 ioZone을 사용하여 SCSI RAID 시스템으로 구성된 저장 장치 시스템과의 성능을 비교 분석하여 가격대비 성능이 비교적 우수함을 보여준다. 끝으로. 향후 SATA(Serial ATA)를 이용한 저장장치 시스템의 전망을 가늠해본다.

• Proceedings of the Korean Vacuum Society Conference
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• 1999.07a
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• pp.174-174
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• 1999

Pt(001)의 깨끗한 표면은 재배열된 (5x20) 또는 (nxn) 구조를 갖는다. 이러한 재배열된 구조는 소？의 가스를 흡착에 대해서도 (1x1)구조로 다시 재배열되는 재배열인 쉽게 풀리는 준안정적 재배열 구조를 갖는 표면이다. Pt(100) 표면 위에 Ni과 같은 금속을 흡착시키는 경우도 동일하게 표면의 장력을 해소시켜 (1x1) 표면을 만든다. Pt와 Ni과 같은 덩어리 상태에서 Pt와 Ni가 질서있게 교차되어 배열되는 합금이 쉽게 이루어지는 물질들로 잘 알려져 있고, 이 합금은 Pt나 Ni와 동일한 규칙적인 fcc 구조를 갖는다. 따라서 Pt(100) 표면 위에 Ni를 흡착시키는 것은 Nm/Cu(100)과 같은 표면합금이나 Mn/Ag(1000에서 보이는 2층으로 된 표면 합금과 같은 표면 근방에 국한된 질서있는 표면 합금의 가능성이 있다. 또한 Ni/Pt(100)은 Ni과 Pt가 3대 1의 비로 조합될 때 나타나는 Ni3Pt의 층별구조인 표면에 Ni가 채워져 있고, 다음 층에 Ni와 Pt가 50%씩 질서 있게 섞여 있는 형태의 구조 즉 표면 밑 합금이 나타날 수 있는 가능성이 있는 물질계라는 점에서 관심을 갖게 한다. 본 연구는 LEED를 이용하여 Ni/Pt(100) 박막의 층별구조를 확인하고자 한다. PtNi 합금은 ATA(average t-matirx approximation)을 이용한 LEED 분석이 잘 적용되는 물질계로 알려져 있고, 본 연구는 ATA를 적용한 LEED I/V 분석을 통하여 Ni가 성장된 Pt(100) 표면의층별 농도비와 층별 구조를 구하고자 한다. 실험은 기본 압력이 3x10-11torr인 챔버에서 이루어졌으며, 증착시 압력은 5x10 torr이고, 증착은 열증발 방법을 이용하였다. Ni가 증착됨에 따라 (nxn) 재배열 표면에 기인한 extra spot들의 세기는 점차 감소하고 특정 증착량 이상에서부터 이 (nxn)의 spot들이 사라지고 깨끗한 (1x1) 패턴이 나타난다. 계속되는 증착량의 증가에 대해서도 이 (1x1) 형태는 유지되며, 표면의 질서에 따르는 c(2x20 패턴은 보이지 않았다. (1x1) LEED spot를 보임에도 불구하고 덩어리 절단 형태의 구조를 기반으로 한 LEED I/V 분석으로는 잘 맞출수 없었다. 이것은 Ni가 일정 이상 흡착된 경우 그 구조가 덩어리 절단 형태의 fcc(100) 구조와 벗어난 구조를 가지는 것으로 보인다.

• The Korean Journal of Quaternary Research
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• v.20 no.2
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• pp.51-57
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• 2006

Terrace stratigraphy of the southeastern coastal areas of Korea is reappraised on the basis of terrace mapping and geochronology. Coastal terraces are divided into uHT ($90{\sim}130\;m$), HT ($63{\sim}86m$), MT ($36{\sim}55\;m$), and LT ($8{\sim}25\;m$) according to altitude. Among these, the Lower Terrace I is interpreted to have formed during MIS 5e based on Tephras Aso-4 (MIS 5c), Ata(MIS 5d or 5e) and OSL data. The age of Lower Terrace II is thought to be MIS 5a based on tephras and OSL data. The uplift rate in the SE part of Korea during the formation of the Lower Terrace (i.e. the MIS 5) ranges from 0.08 to 0.25 mm/yr and averages as 0.15 mm/yr. Such value is quite small in comparison to that of Japan, Taiwan or many other tectonically active areas in the world.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.30 no.2
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• pp.74-82
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• 2019

Objectives: The objective of this study was to investigate clinical and neuropsychological factors associated with treatment response and adverse events of atomoxetine in children with attention-deficit/hyperactivity disorder (ADHD) in Korea. Methods: Children with ADHD were recruited at the Department of Psychiatry of Asan Medical Center from April 2015 to April 2018. Diagnoses of ADHD and comorbid psychiatric disorders were confirmed with the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version. The subjects were subsequently treated with atomoxetine for 12 weeks and illness severity was scored using the ADHD Rating Scale, Clinical Global Impression-Severity scale (CGI-S) and/or Improvement scale (CGI-I), at pre- and post-treatment. They also completed the Advanced Test of Attention (ATA), while their caregivers completed the Korean Personality Rating Scale for Children (KPRC) at pre- and post-treatment. Independent t-test, Fisher's exact test, ${\chi}^2$ test, mixed between-within analysis of variance and correlation analysis were used for statistical analysis. Results: Sixty-five children with ADHD (mean age: $7.9{\pm}1.4years$, 57 boys) were enrolled, of which, 33 (50.8%) were treatment responders. Scores on the social dysfunction subscale of the KPRC (p=0.021) and commission errors on the visual ATA (p=0.036) at baseline were higher in treatment non-responders than in responders; however, the statistical significances disappeared after adjusting for multiple comparisons. Mood changes were also observed in 13 subjects (20.0%), and three of them discontinued atomoxetine due to this. Additionally, atomoxetine-emergent mood change was observed more frequently in girls (p=0.006), while the intelligence quotient (p=0.040) was higher in those subjects with mood changes than in those without. Conclusion: The results of our study suggest that clinical and neuropsychological factors could be associated with treatment response or adverse events of atomoxetine in children with ADHD. Further long-term studies with larger samples are needed.

• Proceedings of the Korea Information Processing Society Conference
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• 2007.05a
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• pp.1237-1239
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• 2007

This paper proposes a virtual storage system for smart home/office embedded devices by utilizing AoE and HyperSCSI protocols. It relies on current Ethernet infrastructures and aims to provide a low-cost solution for the storage limitation problem on embedded devices. We choose AoE (ATA over Ethernet) and HyperSCSI in our implementation because they are relatively lightweight compared to other network storage protocols such as NFS(Network File System), CIFS(Common Internet File System) and iSCSI(internet Small Computer System Interface). The design and architecture of our proposed virtual system as well as the prototype demonstration are presented in this paper.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.8
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• pp.1038-1045
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• 2000

An experimental study was carried out to delineate the flow characteristics in a closed countescurrent two-phase thermo syphon with concentric tubes. This is to be installed in the HANARO research reactor as a part of a Cold Neutron Source(CNS). In the present investigation, experiments ata room temperature with Freon-II3 as a moderator were performed. Results show that, based on the magnitude of pressure fluctuation, the flow regimes could be divided into 4 distinct ones in the ($V_f,\;Q_i$) plane, where $V_f$ represents the volume of the charged liquid and $Q_i$ the heat load: a stable flow regime, an oscillatory flow regime, a restablized flow regime and a dryout flow regime. For $V_f$>2.5l, the flow is stable at low $Q_i$. However, as $Q_i$ increases, the flow becomes oscillatory and finally restablizes As $V_f$ increases, the oscillation amplitude decreases, reaching to the restablized flow region at low $Q_i$, and the liquid level in the moderator cell remains high. In the oscillatory flow regimes, for a fixed VI; the oscillating period of time varies with $Q_i$, having a minimum value at a certain value of $Q_i$. The heat load, where the oscillating period of time is minimum, decreases as $V_f$ increases.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.737-740
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• 2015

Purpose: The study aim was to assess factors that impact on the outcome of radioiodine therapy in patients diagnosed with differentiated thyroid carcinoma (DTC). Materials and Methods: We performed a retrospective cohort study on 256 patients with DTC who underwent thyroidectomy and received radioiodine therapy during December 2003 to January 2012. All patients were followed up for at least 1 year. They were considered diseasefree by the criteria of the revised American Thyroid Association Management Guideline for Patients with Thyroid nodules and DTC (ATA guideline 2009). Results: On Cox univariate analysis, factors associated with disease-free status were age<45, stage I tumor, low risk group by histopathology, unifocal tumor involvement, stimulated serum Tg level at 1st dose of radioiodine therapy and no distant metastasis from 1st post-treatment WBS (post RxWBS). On multivariate analysis, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy < 30 ng/mL were the significant prognostic factors that increased disease-free rate by 1.73 times and 2.60 times, respectively (P-value <0.05). Conclusions: Factors affecting the outcome of radioiodine therapy in our study were age, stage, risk of recurrence by histopathology, unifocal tumor involvement and 1st postRxWBS findings. From these factors, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy were independent prognostic factors that substantial increase the disease-free rate.