• Physical Therapy Korea
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• v.15 no.1
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• pp.54-60
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• 2008

The purpose of the study was to investigate the effectiveness of self-paced walking exercises in elderly women with hypertension, hyperglycemia, and hypercholesterolemia. Thirty-eight elderly women with hypertension, hyperglycemia, and hypercholesterolemia (16 hypertension, 11 hyperglycemia, 11 hypercholesterolemia), aged between 65 and 80, were invited to participate in this study. Each subject participated in a self-paced walking exercise five times a week for twelve weeks from 26 June to 16 September 2006. The changes between pre- and post-exercise were analyzed using the analysis of a paired t-test with the SPSS version 12.0 package program. There were significant decreases in systolic blood pressure (p<.01) and diastolic blood pressure (p<.05), blood glucose(p<.05), and cholesterol in the blood (p<.01). These results show that self-paced walking exercises may be helpful in treating elderly women with hypertension, hyperglycemia, and hypercholesterolemia.

• YAKHAK HOEJI
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• v.45 no.1
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• pp.85-92
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• 2001

Nitric oxide is a tonically produced vasodilator that maintains blood pressure in the normal animal. The chronic inhibition of nitric oxide synthase (NOS) elicits the hypertension in rats. However, the mechanism of hypertension induced by chronic inhibition of NOS is not clear. Thus, to clarify the mechanism of the occurance of hypertension, the changes in $\alpha$-adrenergic systems in rats treated with NOS inhibitors for 21 days were examined. Chronic administration of L-NAME significantly increased in the basal blood pressure, but chronic administration of 7-nitroindazole did not. Phenylephrine and G-protein stimulator elicited the more potent contraction in the aorta of the L-NAME-induced hypertensive rats. However when the contractile responses by phenylephrine and G-protein stimulator were calculated the proportion to the contraction by 25 mM KCL, there was no difference between the vehicle-treated rats and the L-NAME-treated rats. The density of $\alpha$-adrenergic receptors in aortic tissue was not changed by the chronic inhibition of NOS. These results suggest that hypertension induced by chronic inhibition of NOS is due to the inhibition of eNOS and the increased responses to the adrenergic drugs are due to the changes of the intracellular contactile mechanism of aortic tissue rather than the changes of receptor density.

• Journal of the Korea Society of Computer and Information
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• v.21 no.8
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• pp.117-126
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• 2016

The purpose of this study was to explain the influence of depression on the life satisfaction of the elderly with hypertension. Also, we were focusing whether there is a mediating effect of subjective health status between depression and life satisfaction of the elderly with hypertension. 2,198 persons with hypertension over 65 years of age were selected from the data of KLoSA(Korean Longitudinal Study of Ageing), administered by The Korea Employment Information Service in 2014. Life satisfaction was measured by 10-Likert. The depression measured by CES-D10. The mediating variable is subjective health status measured by 5-Likert. As the method of analysis, the multiple regressions were used with SPSS 19.0. The result of the study shows that depression has a negative influence on life satisfaction and a negative influence on subjective health status. It was also verified that the subjective health status variable has a mediating effect between depression and life satisfaction. These results present the importance of psychological approach for the health promotion experts intervening with the elderly with hypertension.

• The Journal of Korean Medicine
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• v.20 no.4
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• pp.93-97
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• 2000

Backgrounds and Purpose: Hypertension is a common origin for stroke, heart disease, etc. Clinical management is needed to prevent these diseases. It has been said that auricular acupuncture treatment can be used for the control of hypertension. In this study, we studied the effects of auricular acupuncture on mild hypertension. Materials and Methods: Clinical study was performed on 22 stroke patients who didn't take the antihypertensive drugs. They were admitted in Kyunghee University, Hospital of Oriental Medicine. We checked patients' 24-hour blood pressure by Ambulatory Blood Pressure Monitor and did auricular acupuncture treatment for one day and rechecked blood pressure for 24-hours. We compared the blood pressure between, before, and after auricular acupuncture treatment by Wilcoxon test. The acupuncture points were KOHYOLABJUM, NAEBUNBI, SHINMUN, SHIM, KANGABJUM. They were all on the auricular. Results: After auricular acupuncture treatment, systolic and diastolic hypertension decreased significantly(p<0.05), but heart rates didn't change significantly. Conclusions: These results suggest that Auricular acupuncture treatment may be used for antihypertensive purpose. About the efficacy and safety, further study is needed.

• Animal cells and systems
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• v.4 no.1
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• pp.87-90
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• 2000

Essential hypertension is a multifactorial disease, and has been shown to be associated with insulin resistance. The relationship between the genetic variation of the insulin receptor (INSR) gene and essential hypertension In Korean population was investigated by the Nsi 1 restriction fragment length polymorphism (RFLP) pattern of this gene. The observed genotype frequencies of INSR gene were not deviated from those expected for the Hardy-Weinberg equilibrium (HWE), but a significant association was observed between essential hypertension and N1 allele of Nsi 1 RFLP at the INSR gene ($X^2$-test; P<0.05). Moreover, the frequency of N1 allele was significantly different between normotensives and essential hypertensives in subgroups that were not obese ($X^2$-test; P<0.05). These data suggest that the Nsil RFLP of INSR gene may be a useful genetic marker for essential hypertension in Korean population.

• Journal of muscle and joint health
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• v.24 no.1
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• pp.24-36
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• 2017

Purpose: The purpose of the study was to comprehensively explore the factors influencing quality of life and its measurements in patients with hypertension. Methods: Based on the PRISMA statement and NECA systematic literature review guideline, a systematic literature review was conducted in this study. To search studies related to quality of life in patients with hypertension, multiple electronic databases were used using a combination of key words 'hypertension' and 'quality of life'. Throughout this process, a total of 983 studies were identified. Then, the second selection processes and quality assessment were conducted by four investigators independently. Finally, a total of 19 studies were included for the analysis. Results: Results showed that quality of life was focused on the health-related quality of life, and the SF-36 was one of the most frequently used measurements. The factors influencing quality of life were categorized into sociodemographic, health-related, health behavioral, and psychosocial variables. Conclusion: Researchers need to consider these multiple factors to promote quality of life in patients with hypertension.

• Research in Community and Public Health Nursing
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• v.32 no.3
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• pp.303-311
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• 2021

Purpose: This study investigated the health literacy level of, the hypertension knowledge of, the self-management behaviors of, and the factors influencing self-management behaviors of the hypertensive elderly population residing in the urban and rural areas. Methods: Data were collected from November to December 2017 by the trained research staff. For two months, a total of 160 subjects in urban and rural areas who had been taking antihypertensive medications consented to participate in the project. 157 participants completed the survey. Results: The health literacy score of the hypertensive elderly subjects was at 48.38±8.13, the hypertension knowledge score at 8.90±2.01 points, and the self-management behaviors score at 52.96±8.08. The factor that influenced the self-management behaviors of the hypertensive elderly subjects the most was the health literacy, followed by the residential area, and the hypertension knowledge. Conclusion: The research findings suggest that a health promotion program for the hypertensive elderly population should be designed in consideration of the health literacy, the area of residence and the hypertension knowledge of the elderly.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.55-56
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• 2022

Hypertension is a severe health problem and increases the risk of other health issues, such as heart disease, heart attack, and stroke. In this research, we propose a machine learning-based prediction method for the risk of chronic hypertension. The proposed method consists of four main modules. In the first module, the linear interpolation method fills missing values of the integration of gas and meteorological datasets. In the second module, the OrdinalEncoder-based normalization is followed by the Decision tree algorithm to select important features. The prediction analysis module builds three models based on k-Nearest Neighbors, Decision Tree, and Random Forest to predict hypertension levels. Finally, the features used in the prediction model are explained by the DeepSHAP approach. The proposed method is evaluated by integrating the Korean meteorological agency dataset, natural gas leakage dataset, and Korean National Health and Nutrition Examination Survey dataset. The experimental results showed important global features for the hypertension of the entire population and local components for particular patients. Based on the local explanation results for a randomly selected 65-year-old male, the effect of hypertension increased from 0.694 to 1.249 when age increased by 0.37 and gas loss increased by 0.17. Therefore, it is concluded that gas loss is the cause of high blood pressure.

• Journal of Korean Medicine for Obesity Research
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• v.23 no.2
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• pp.86-97
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• 2023

Objectives: The purpose of this study is to review clinical studies related to the effect of Traditional Chinese Medicine (TCM) on moderate to severe obese patients with hypertension. Methods: Clinical studies from the China National Knowledge Infrastructure (CNKI) were searched by specific keywords and criteria. Total of 7 randomized controlled trials were selected and analyzed. Results: Various evaluation methods were used to see the effect of TCM compared to conventional western medicine. Most of the studies used herbal medicine combined with conventional anti-hypertensive western medicine. The effective rate of anti-hypertension was higher when TCM was added to conventional anti-hypertensive medicine. Traditional medicine treatment showed significant effect on lowering blood pressure and body mass index. Conclusions: Based on the results of the clinical studies from China, TCM can be a valuable option for moderate to severe obese patients with hypertension. Applying Traditional medicine has a significant effect on lowering blood pressure and weight loss. Combining herbal medicine can be worthy of clinical promotion and application for moderate and severe obese patients with hypertension.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.10
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• pp.4686-4693
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• 2012

The present study was conducted to identify the factors related to the hypertension, and to offer the evidence of 1st prevention of hypertension. 2,230 male workers aged 30-59 years were observed the relationships between hypertension and age, BMI, glucose intolerance, smoking, alcohol drinking, regular exercise, eating habits using data from health check-ups in 2011. As a results, the incidence rate of hypertension was 18.8% of 30-39 year old group, 23.8% of 40-49 year old group, 33.0% of 40-49 year old group. The incidence rate of hypertension was significantly higher as age and BMI ascend, and it was higher in the group of abnormal glucose intolerance, regular alcohol intake, no regular exercise than their respective counterparts. The multivariable-adjusted odds ratio of hypertension increased significantly as there is an increase in age, and the group of abnormal glucose intolerance, smoking, regular alcohol intake, no regular exercise. In conclusion, obesity, glucose intolerance, alcohol intake, and physical inactivity are risk factors for hypertension, therefore we need the control of these factors for 1st prevention of hypertension.