• Animal cells and systems
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• v.13 no.3
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• pp.283-288
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• 2009

The ubiquitous plasma membrane $Na^+/H^+$ exchanger 1 (NHE1) is rapidly activated in response to various extracellular stimuli and maintains normal cytoplasmic pH. Yeast two-hybrid screening was used in order to identify proteins interacting with NHE1 using its cytoplasmic domain as a bait from HeLa cDNA library. One of the interacting cDNA clones was human Lactate dehydrogenase B (LDHB). In vitro translated LDHB was pulled down together with GST-NHE1.cd protein in the GST pull down assay, confirming the interaction in vitro. LDHB antibody immunoprecipitated endogenous LDHB together with NHE1 from H9c2 cells, validating cellular interaction between NHE1 and LDHB. Subsequent analysis revealed that the overexpression of LDHB increased intracellular PH, implying opening of the NHE1 transporter. Moreover, overexpression of LDHB activated caspase 3 and induced cell death, consistent with the expected phenotype of hyper-activation of NHE1. Collectively, our data indicate that LDHB modulates NHE1 activity via physical interaction.

• Annual Conference of KIPS
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• 2006.05a
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• pp.757-760
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• 2006

고성능 컴퓨팅 자원(Computing Resources)을 네트워크를 통하여 하나로 연동하여 단일 컴퓨팅 작업을 수행하는 그리드 컴퓨팅(Grid Computing)에 대한 연구가 최근 활성화 되고 있다. 이에 본 논문에서는 그리드를 구성하는 노드에 작업을 분배하는 메타 스케줄링(Metascheduling)과 노드내의 작업을 프로세서에 적절히 할당하는 작업 스케줄링 방법을, 작업 큐와 두 개의 백필 큐를 사용하는 혼합 기법을 사용하여, 작업 지연율(Slowdown Ratio)을 줄이고 그리드 컴퓨팅의 이용률(Utilization)을 높이는 방법을 제안하였으며 다양한 실험을 통하여 성능을 평가하였다.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.6
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• pp.34-42
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• 2006

As many systems depend on electronics, concern for fault tolerance is growing rapidly. For example, a car with its steering controlled by electronics and no mechanical linkage from steering wheel to front tires(steer-by-wire) should be fault tolerant because a failure can come without any warning and its effect is devastating. In order to make system fault tolerant, there has been a body of research mainly from aerospace field. This paper presents the structure of predictive smoothing voter that can filter out most erroneous values and noise. In addition, several numerical simulation results are given where the predictive smoothing voter outperforms well-known average and median voters.

• Proceedings of the KIEE Conference
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• 2006.04b
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• pp.341-343
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• 2006

In this paper an integrated model of PV-AF (Photovoltaic-Active Filter) and PV-SPE (Photovoltaic Solid Polymer Electrolyte) system using PSCAD/EMTDC were explained in detail. The main concept of PV-AF system starts from the "harmonics". In order to deliver power to utility, PV system essentially needs a converter system. Here PV-AF system adds the function of active filter to the converter system installed in PV system, which was introduced already in several papers. PV-SPE system has been studied as a replacement of existing hydrogen production technology that emits large amount of carbon dioxide into atmosphere. Until now, these two systems, PV-AF and PV-SPE, have been considered separately. However, in this paper, characteristics and advantages of combined system are discussed in detail.

• Proceedings of the KIEE Conference
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• 1996.07a
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• pp.59-61
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• 1996

Fuel cell systems offer high efficiencies for energy conservation for transportation application. In addition, they can operate on alcohols and alternative fuels, while producing little or no noxious emissions. The goal of the fuel cell in transportation should be research and commercialization of fuel cell vehicles as economic competitors for internal combustion engine vehicle. The objective of the present study is to analyze feasibility of the fuel cell/battery combination as a power source for a bus.

• Journal of Korean Society for Quality Management
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• v.38 no.1
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• pp.1-9
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• 2010

Service Oriented Architecture(SOA) is an enterprise-scale IT architecture for linking software resources available on the network. SOA is believed to become the future enterprise solution that promises the agility and flexibility by integrating business processes through composition of the software services across enterprises. The first step for SOA construction is to identify the services. In this paper, we present a process-based service identification methodology for SOA through a case study of an IT company. Our methodology is composed of three steps: Processes (business & technical processes) analysis and systems analysis, Service candidates selection, and Service evaluation and construction planning. This framework would be practical and could be accepted to other organizations as it has been developed through the real case.

• Journal of Korean Society for Quality Management
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• v.36 no.3
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• pp.34-44
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• 2008

This research proposes a design method based on the statistical characteristics of the Shewhart control chart incorporated with 2 of 2 and 2 of 3 runs rules respectively. A Markov chain approach is employed in order to calculate the in-control and out-of-control average run lengths(ARL). Two different control limit coefficients for the Shewhart scheme and the runs rule scheme are derived simultaneously to minimize the out-of-control average run length subject to the reasonable in-control average run length. Numerical examples show that the statistical performance of the hybrid control scheme are superior to that of the original Shewhart control chart.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1051-1051
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• 2001

In 1989, at the 2nd ICNIRS Meeting in Tsukuba, I projected certain directions for NIR technology would take in the future. Among those projections were: (1) An inrush of companies producing FT-NIR instruments. (2) Hybrid NIR Systems (3) Hand-held NIR Technology. All three thrusts have resulted in numerous commercial offerings over the last 12 years Hand-held technology for all fields is growing at an astonishing rate. To date, NIR work at North Carolina State University has produced four (4) hand-held NIR units for: (1) Nicotine and Moisture in tobacco, (2) Vanillin and Moisture in Vanilla Beans, (3) Protein, Moisture and Nitrogen in plant tissue, (4) Chlorophyll and Moisture in Growing Plants: A NIR Spectrometer for Developing Countries. This paper will discuss these developments, including design and performance data.

• Proceedings of the KIEE Conference
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• 1991.07a
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• pp.699-702
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• 1991

A servo system requires faster and more accurate dynamic responses. Generally a PD control is mainly used to obtain the precision, and in the other hand a fuzzy control to improve the transient response and to cope with the nonlinearity of systems. Recently hybrid control, which is attempted to combine the advantages of PD control and a Fuzzy control was proposed, but this technique requires complicate design procedures. Therefore in this paper, a Fuzzy controller with a series of membership functions, and various sampling periods and rules, was designed on the basis of Lyapunov stability theory and auto tuning methods of input scale factors. And also it was showed to have the excellent adaptive performances against internal-external disturbances and the usefulness of this controller from the results of simulations.

• Proceedings of the Materials Research Society of Korea Conference
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• 2003.03a
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• pp.18-18
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• 2003

Natural clays are composed of oxide layers whose thickness is about 1nm and cations existing between the layers. A number of these layers makes primary particles with a height of about 8∼10nm and these primary particles make aggregates with a size of about 0.1∼10$\mu\textrm{m}$. When layered silicate was made to be organophilic, by exchanging the interlayer cations with organic cationic molecules, the matrix polymer can penetrate between the layers to give a nanocomposite, where 1nm-scal clay layers exist separately in a continuous polymer matrix. These nanostructured hybrid organic-inorganic composites have attracted the great interest of researchers over the last 10 years. They exhibit improved performance properties compared with conventional composites, because their unique phase morphology by layer intercalation or exfoliation maximizes interfacial contact between the organic and inorganic phases and enhances interfacial properties. Since the advent of nylon-6/montmorillonite nanocomposite developed by Toyota Motor Co., the studies on layered silicate-polymer nanocomposites have been successfully extended to other polymer systems. They greatly improved the thermal, mechanical, barrier, and even the flame-retardant properties of the polymers.