• Title/Summary/Keyword: human-to-human (H2H)

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Characteristics of Somatotype Classified by the Drop Value of Middle-Aged Women (중년 여성의 드롭치에 따른 체형 특성 연구)

  • Yoon, Ji-Won;Suh, Mi-A
    • The Research Journal of the Costume Culture
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    • v.17 no.6
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    • pp.939-946
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    • 2009
  • This study is to classify the shape of the body by means of the drop value of the middle-age women. Drop value is based on the circumstances of the body deciding the dimentions of the clothes. Therefore, the study based on the drop value seems to decided the measurement of the clothes in making mass production of ready made clothes. In order to put measure items on this study of the value on 'The fifth survey of body measure of Korean', select 785 people in middle-aged women aged from 40 to 59. And considering the characteristic of upper-drop and lower-drop, and swelling belly by accumulated fat, selected five items(Bust Circumstance - Waist Circumstance, Hip Circumstance - Waist Circumstance, Hip Circumstance - Bust Circumstance, Waist Circumstance(Omphalion) - Waist Circumstance, Hip Circumstance - Waist Circumstance(Omphalion)). The result of the study is summarized as follows. Type 1, M type of the body showed the distribution of 32.5% and belonged to low body development style. The line of human body is the nearest of the four bodies in middle-age woman out of whole shapes of 4 types and the line of human body is close to middle-age woman. Type 2, X type of the body showed the distribution of 40.8% and the line of human body remarkably showed. Type 3, H type of the body showed the distribution of 12.4% and the line of human body appears least. This group was larger than any other group in having more fat in the belly above the circumstance of the hip than other groups. Type 4, Y type of the body showed the distribution of 14.4%. This type was upper half of body development style, waist was slender, and there was seldom the bend around the circumstance of belly and hip.

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Uncertainty and Sensitivity Analyses of Human Aggregate Risk Assessment of Benzene using the CalTOX Model (CalTOX 모델을 이용한 벤젠 종합위해성평가의 불확실성 분석과 민감도 분석)

  • Kim, Ok;Lee, Minwoo;Song, Youngho;Choi, Jinha;Park, Sanghyun;Park, Changyoung;Lee, Jinheon
    • Journal of Environmental Health Sciences
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    • v.46 no.2
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    • pp.136-149
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    • 2020
  • Objectives: The purpose of this study was to perform an aggregate human risk assessment for benzene in an industrial complex using the CalTOX model and to improve the reliability and predictability of the model by analyzing the uncertainty and sensitivity of the predicted assessment results. Methods: The CalTOXTM 4.0 beta model was used to evaluate a selected region, and @Risk 7.6 software was used to analyze uncertainty and sensitivity. Results: As a result of performing the aggregate risk assessment on the assumption that 6.45E+04 g/d of benzene would be emitted into the atmosphere over two decades, 3% of the daily source term to air remained in the selected region, and 97% (6.26E+04 g/d) moved out of the region. As for exposure by breathing, the predicted LADDinhalation was 2.14E-04 mg/kg-d, and that was assessed as making a 99.99% contribution to the LADDtotal. Regarding human Riskcancer assessment, the predicted human cancer risk was 5.19E-06 (95% CI; 4.07E-06-6.81E-06) (in the 95th percentile corresponding to the highest exposure level, a confidence interval of 90%). As a result of analyzing sensitivity, 'source term to air' was identified as the most influential variable, followed by 'exposure time, active indoors (h/day)', and 'exposure duration (years)'. Conclusions: As for the results of the human cancer risk assessment for the selected region, the predicted human cancer risk was 5.19E-06 (95% CI; 4.07E-06-6.81E-06) (in the 95th percentile, corresponding to the highest exposure level, a confidence interval of 90%). As a result of analyzing sensitivity, 'source term to air' was found to be most influential.

Physicochemical and Sensory Characteristics of Rice Cookies Based on Goami 2 with Sesames(White and Black) and Perilla Seeds (흰깨, 검은깨 및 들깨가 고아미 2호를 이용한 쌀쿠키의 이화학적 및 관능적 특성에 미치는 영향)

  • Jung, Young-Jeong;Seo, Han-Seok;Myung, Jyong-Eun;Shin, Jeong-Min;Lee, Eun-Ju;Hwang, In-Kyeong
    • Korean journal of food and cookery science
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    • v.23 no.6
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    • pp.785-792
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    • 2007
  • The aim of this study was to develop rice cookies based on 'Goami 2' rice, and made with sesame (white and black) and perilla seeds. Furthermore, we studied the physicochemical and sensory characteristics of the cookies as well as the alternative effects of the sesames or perilla seeds for butter, where we substituted the sesames or perilla for 30% of the total butter. The pH values of the cookie doughs made with the sesames or perilla seeds were significantly different (p<0.001), whereas the spread factors of the doughs were not significantly different. The Hunter color L-, a-, and b- values were significantly different for the cookies made with the added sesames or perilla seeds (p<0.001). The brittleness of the Goami 2 rice cookies (control) was significantly higher than that of the cookies made with the sesames or perilla (p<0.001). In a descriptive analysis performed by 8 trained panelists, the following sensory characteristics: yellow, black, sweet taste, nutty taste, nutty odor, oily flavor, and off flavor, were significantly different among the cookie samples. In a consumer test by 50 women students, the Goami 2 rice cookies were preferred in the following order: Goami 2 rice cookies with no additions > black sesame cookies > white sesame cookies > perilla cookies. In conclusion, some physicochemical and sensory characteristics of the cookies were different, in relation to being made with or without the sesame or perilla seeds. However, because of the small difference in acceptance among the cookies, the sesame and perilla rice cookies show strong potentials for consumer acceptance. Moreover, the black sesame cookies were more acceptable in terms of butter substitution for the cookie preparation.

Bone Healing in Ovariectomized-rabbit Calvarial Defect with Tricalcium Phosphate Coated with Recombinant Human Bone Morphogenetic Protein-2 Genetically Engineered in Escherichia coli

  • Kim, Jung-Han;Kim, Chang-Joo;Shin, Sang-Hun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.36 no.2
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    • pp.37-49
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    • 2014
  • Purpose: This study compares the bone formation ability of tricalcium phosphate (TCP) with and without recombinant human bone morphogenetic protein-2 (rhBMP-2) and assesses TCP as a carrier of rhBMP-2. Methods: Bilateral round defects (diameter: 8.0 mm) were formed in the cranium of eight New Zealand white rabbits. The defects were grafted with TCP only (control group) or with rhBMP-2-coated TCP (experimental group). The animals were sacrificed at 1st week, 2nd week, 4th week, and 8th week postoperatively; two rabbits sacrificed each time. The skulls were harvested and subjected to radiographic and histological examination. Results: Radiologic evaluation showed faster bone remodeling in the experimental group than in the control group. Histologic evaluation (H&E, Masson's trichrome stain) showed rapid bone formation, remodeling and calcification in the 1st and 2nd week in the experimental group. Immunohistochemical evaluation showed higher expression rate of osteoprotegerin, receptor activator of nuclear factor ${\kappa}B$ ligand, and receptor activator of nuclear factor ${\kappa}B$ in the experimental group at the 1st and 2nd week than in the control group. Conclusion: rhBMP-2 coated TCP resulted in rapid bone formation, remodeling, and calcification due to rhBMP-2's osteogenic effect. TCP performed properly as a carrier for rhBMP-2. Thus, the use of an rhBMP-2 coating on TCP had a synergic effect on bone healing and, especially, bone remodeling and maturation.

Pharmacological Characterization of KR-31125, a Novel Nonpeptide AT1 Receptor Antagonist (안지오텐신 수용체 길항제 KR-31125의 특성에 관한 연구)

  • Lee, Sung-Hou
    • Journal of Life Science
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    • v.20 no.6
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    • pp.831-837
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    • 2010
  • KR-31125 (2-butyl-5-dimethoxymethyl-6-phenyl-7-methyl-3-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-3H-imidazo[4,5-b]pyridine) is a potent inhibitor of angiotensin II type 1 ($AT_1$) receptors in human recombinant $AT_1$ receptors and rabbit aorta. These in vitro studies revealed that KR-31125 inhibited specific [$^{125}I$] [$Sar^1$, $Ile^8$]-angiotensin II binding to human recombinant $AT_1$ receptors in a concentration dependent manner with an $IC_{50}$ value of $19.72{\pm}2.65$ nM. However, no interaction with $AT_2$ receptors was detected as displayed by the competition binding of [$^{125}I$] CGP 42112A to human recombinant $AT_2$ receptor. The binding action was also confirmed as a competitive mode that was identical to the previously studied compound, losartan. In addition, KR-31125 caused a nonparallel shift to the right in the concentration response curves to angiotensin II with a 30-80% decrease in the maximum contractile responses ($pK_B$: 7.63). Compared to the previous studies with losartan that showed a parallel right shift in the maximum contractile responses to AII ($pA_2$: 7.59), KR-31125 presented a different mode of action with a similar potency to losartan. These results demonstrate that KR-31125 is a highly potent and $AT_1$ selective angiotensin II receptor antagonist that can be applied to the fields of new diagnostic and research tools with upcoming in vivo study results.

Insulin Cannot Activate Extracellular-signal-related Kinase Due to Inability to Generate Reactive Oxygen Species in SK-N-BE(2) Human Neuroblastoma Cells

  • Hwang, Jung-Jin;Hur, Kyu Chung
    • Molecules and Cells
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    • v.20 no.2
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    • pp.280-287
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    • 2005
  • The insulin-mediated Ras/mitogen-activated protein (MAP) kinase cascade was examined in SK-N-BE(2) and PC12 cells, which can and cannot produce reactive oxygen species (ROS), respectively. Tyrosine phosphorylation of the insulin receptor and insulin receptor substrate 1 (IRS-1) was much lower in SK-N-BE(2) cells than in PC12 cells when the cells were treated with insulin. The insulin-mediated interaction of IRS-1 with Grb2 was observed in PC12 but not in SK-N-BE(2) cells. Moreover, the activity of extracellular-signal-related kinase (ERK) was much lower in SK-N-BE(2) than in PC12 cells when the cells were treated with insulin. Application of exogenous $H_2O_2$ caused increased tyrosine phosphorylation and Grb2 binding to IRS-1 in SK-N-BE(2) cells, while exposure to an $H_2O_2$ scavenger (N-acetylcysteine) or to a phophatidylinositol-3 kinase inhibitor (wortmannin), and expression of a dominant negative Rac1, decreased the activation of ERK in insulin-stimulated PC12 cells. These results indicate that the transient increase of ROS is needed to activate ERK in insulin-mediated signaling and that an inability to generate ROS is the reason for the insulin insensitivity of SK-N-BE(2) cells.

Quality Characteristics of Pear Jam with Added Ginger Powder (건조 방법을 달리한 생강가루를 첨가한 배잼의 품질 특성)

  • Rho, Jeong-Ok;Park, Hee-Jin;Lee, Young-Sook
    • The Korean Journal of Food And Nutrition
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    • v.24 no.2
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    • pp.159-165
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    • 2011
  • This study was carried out to investigate the quality characteristics of pear jam containing fresh ginger(G1) and ginger powders; dried ginger powder(G2), freeze-dried ginger powder(G3), and hot-air dried ginger powder(G4). The moisture, crude protein, and crude ash content of the control group were significantly higher than those of the experimental groups (p<0.001, p<0.05, p<0.01). The pH of the dried ginger powder added jam(G2) was the lowest(p<0.05). Texture profile analysis found that the dried ginger powder added jam(G2) had the highest firmness, consistency, cohesiveness, and resistance to flow/viscosity among all samples(p<0.001). Regarding the spread-meter value of the pear jam, the control group (G1) and hot air-dried ginger powder added jam(G4) had the highest values. The dried ginger power added jam(G2) had the lowest value among the samples(p<0.01). Regarding the color values of the pear jam, the control group(G1) had the highest L and b values. Hot-air dried ginger powder added jam(G4), on the other hand, had the lowest(p<0.001). The opposite was true for a value: hot-air dried ginger powder added jam(G4) had the highest. From the sensory evaluation, a positive trend was observed for the appearance of the dried ginger powder added jam(G2)(p<0.001). For sweetness, the dried ginger powder added jam(G2) had the highest value. A positive trend was observed for the overall acceptability of the dried ginger powder-added jam(G2)(p<0.001). Therefore, the dried ginger powder-added sample(G2) seemed to be the most appropriate to make pear jam with high acceptability.

H.264 Deblocking Filter Implementation Method Considering $8\times8$ Block-Based Post-Filtering ($8\times8$ 블록기반의 후처리필터링을 고려한 H.264 블록화 현상 제거부 설계 기법)

  • Kim Sung Deuk;Cho Hong Kyu
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.2 s.302
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    • pp.19-26
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    • 2005
  • After various video coding standards such as H.263, MPEG-4, and H.264 have been introduced, there has bun strong need to support the multiple standards with limited resources efficiently. In terms of deblocking Inter which plays an important role in improving visual quality, K264 deblocking filter implementation has different aspects as compared with traditional $8\times8$ block-based post-filter implementation. Analyzing the differences, this paper proposes a H.264 deblocking filter implementation method that supports $8\times8$ block-based post-filtering for the traditional video coding systems. In the proposed implementation method the block boundaries to he filtered are adaptively chosen for $8\times8$ and $4\times4$ block boundary filtering. Since the filtered result is selectively used for motion compensation or not, both loop-filtering and post-filtering can be achieved. A quantization parameter conversion unit that converts H.263 quantization parameters to H.264 quantization parameters is utilized by examining the $8\times8$ block boundary errors based on human visual system. Since the original nature of the H.264 deblocking filter is well expanded to the $8\times8$ block-based post-filter with minor modifications, the proposed implementation method is suitable to implement the deblocking function of the multiple video standards such as H.263, MPEG-4, and K264, efficiently.

Effect of a dual trigger on oocyte maturation in young women with decreased ovarian reserve for the purpose of elective oocyte cryopreservation

  • Kim, Se Jeong;Kim, Tae Hyung;Park, Jae Kyun;Eum, Jin Hee;Lee, Woo Sik;Lyu, Sang Woo
    • Clinical and Experimental Reproductive Medicine
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    • v.47 no.4
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    • pp.306-311
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    • 2020
  • Objective: The aim of this study was to determine whether co-administration of a gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG) for final oocyte maturation improved mature oocyte cryopreservation outcomes in young women with decreased ovarian reserve (DOR) compared with hCG alone. Methods: Between January 2016 and August 2019, controlled ovarian stimulation (COS) cycles in women (aged ≤35 years, anti-Müllerian hormone [AMH] <1.2 ng/mL) who underwent elective oocyte cryopreservation for fertility preservation were retrospectively analyzed. Results: A total of 76 COS cycles were triggered with a GnRH agonist and hCG (the dual group) or hCG alone (the hCG group). The mean age and serum AMH levels were comparable between the two groups. The duration of stimulation, total dose of follicle-stimulating hormone used, and total number of oocytes retrieved were similar. However, the number of mature oocytes retrieved and the oocyte maturation rate were significantly higher in the dual group than in the hCG group (p=0.010 and p<0.001). After controlling for confounders, the dual-trigger method remained a significant factor related to the number of mature oocytes retrieved (p=0.016). Conclusion: We showed improved mature oocyte collection and maturation rate with the dual triggering of oocyte maturation in young women with DOR. A dual trigger appears to be more beneficial than hCG alone in terms of mature oocyte cryopreservation for young women with DOR.

Survey on Food Habits, Health Condition and Precaution for Disease for the Health Improvement of Community People in Taejon (대전 지역 주민의 건강 향상을 위한 식습관 및 건강상태, 질병 대처 방안에 관한 기초자료와 교육 요구도 조사)

  • Yoon, Eun-Young;Lim, Young-Hee;Wang, Soo-Gyung;Koo, Nan-Sook
    • Korean Journal of Human Ecology
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    • v.7 no.1
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    • pp.205-216
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    • 1998
  • The objectives of this study were to investigate some problems related to health and to identify citizen's needs related to nutrition education program. The data were analyzed by using $x^2$-test, t-test, ANOVA and multiple range test. The food habits score was 70.0 of 100. The score of man was 69.0, while that of woman was 72.6. Since woman's food habit was better than man, education to man is more needed. Man's BMI was 22.5 and that of woman was 21.4. W/H ratio of man was 0.85 and that of woman was 0.80. BMI and W/H ratio increased as age increases. Systolic blood pressure was 123.5mmHg and diastolic blood pressure was 83.2mmHg. All age groups need the education of blood pressure control. Since subjects who did regular exercise were only 26.3%, these community people needed more regular exercise, specially woman. It turned out that subjects were afraid of cancer, hypertension, cerebral vascular diseases which are related with food habits. The disease or symptom having the highest mobility were dental disease, gastroenteric disorder, headache and constipation. They asked for counselling about health, diet therapy, protection methods of disease and menu planning etc. The program of education for health and good food habits should be developed according to subjects's age, sex, education etc. These results showed primary needs on the curriculum of citizen's education program for enhancing health. In addition, we suggest the research on the practical curriculum of nutrition education program.

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