• Steel and Composite Structures
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• v.51 no.6
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• pp.647-659
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• 2024

Given the increased interest in enhancing structural sustainability, the current study sought to apply multiobjective optimization to a footbridge with a steel-concrete composite I-girder structure. It was considered as objectives minimizing the cost for building the structure, the environmental impact assessed by CO2 emissions, and the vertical accelerations created by human-induced vibrations, with the goal of ensuring pedestrian comfort. Spans ranging from 15 to 25 meters were investigated. The resistance of the slab's concrete, the thickness of the slab, the dimensions of the welded steel I-profile, and the composite beam interaction degree were all evaluated as design variables. The optimization problem was handled using the Multiobjective Harmony Search (MOHS) metaheuristic algorithm. The optimization results were used to generate a Pareto front for each span, allowing us to assess the correlations between different objectives. By evaluating the values of design variables in relation to different levels of pedestrian comfort, it was identified optimal values that can be employed as a starting point in predimensioning of the type of structure analyzed. Based on the findings analysis, it is possible to highlight the relationship between the structure's cost and CO2 emission objectives, indicating that cost-effective solutions are also environmentally efficient. Pedestrian comfort improvement is especially feasible in smaller spans and from a medium to a maximum level of comfort, but it becomes expensive for larger spans or for increasing comfort from minimum to medium level.

• Explosives and Blasting
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• v.32 no.3
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• pp.18-25
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• 2014

Ground vibration and noise from blasting operation are known to be the most representative constituents which can cause human and material damage. In this study, the effect of delay time on ground vibration is investigated by adopting seven different delay times in bench blasting. For each delay time, three blasting operations were performed. The prediction equations for blasting vibration are derived from 50 sets of measurement and the time theory of Langefors is evoked in the analysis of the blasting vibrations and frequencies. For the delay times of 8 ms and 28 ms, the average values of ground vibration are 5.76 cm/sec and 5.75 cm/sec, respectively, which are considerably low. Also the cyclic variation in the vibration measurements with the delay time confirms the interference effect. From the application of the measurements of blasting vibration and frequency to the time theory of Langefors, it is concluded that the optimum delay times are 8 ms and 24 ms for the test site.

• Steel and Composite Structures
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• v.49 no.5
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• pp.487-502
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• 2023

In the realm of nanotechnology, the nonlocal strain gradient theory takes center stage as it scrutinizes the behavior of spinning cantilever nanobeams and nanotubes, pivotal components supporting various mechanical movements in sport structures. The dynamics of these structures have sparked debates within the scientific community, with some contending that nonlocal cantilever models fail to predict dynamic softening, while others propose that they can indeed exhibit stiffness softening characteristics. To address these disparities, this paper investigates the dynamic response of a nonlocal cantilever cylindrical beam under the influence of external discontinuous dynamic loads. The study employs four distinct models: the Euler-Bernoulli beam model, Timoshenko beam model, higher-order beam model, and a novel higher-order tube model. These models account for the effects of functionally graded materials (FGMs) in the radial tube direction, giving rise to nanotubes with varying properties. The Hamilton principle is employed to formulate the governing differential equations and precise boundary conditions. These equations are subsequently solved using the generalized differential quadrature element technique (GDQEM). This research not only advances our understanding of the dynamic behavior of nanotubes but also reveals the intriguing phenomena of both hardening and softening in the nonlocal parameter within cantilever nanostructures. Moreover, the findings hold promise for practical applications, including drug delivery, where the controlled vibrations of nanotubes can enhance the precision and efficiency of medication transport within the human body. By exploring the multifaceted characteristics of nanotubes, this study not only contributes to the design and manufacturing of rotating nanostructures but also offers insights into their potential role in revolutionizing drug delivery systems.

• Journal of Biomedical Engineering Research
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• v.45 no.1
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• pp.43-48
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• 2024

The prevalence of obesity and its complications is steadily increasing worldwide. It is essential to understand cellular level metabolism and microenvironment to treat diseases related to lipid metabolism. Mechanical loading can activate signaling pathway by stimulating cells, especially vibration loading known to inhibit adipogenesis, so it has been studied as a treatment for obesity. Also, vibration loading can affect the inside of the human body non-invasively. Another clue to reducing adipose tissue is browning, which means that white adipocytes changes to brown adipocyte. In this study, we design and developed a device that that can control cell-cell contact, and vibration simulation device. Using these two devices, we investigated responses of cells to vibration loading. Protein expression associated with browning and adipogenesis were analyzed. In conclusion, vibration loading can be transmitted through cell contact and loading applied to the cells can induce browning and inhibit adipogenesis of preadipocytes. These results suggest the possibility that vibrations could be a treatment for obesity.