• The Journal of the Acoustical Society of Korea
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• 제23권3E호
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• pp.85-90
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• 2004

This paper presents two kinds of new approaches, one of which is concerned with recognition of emotional speech such as anger, happiness, normal, sadness, or surprise. The other is concerned with emotion recognition in speech. For the proposed speech recognition system handling human speech with emotional states, total nine kinds of prosodic features were first extracted and then given to prosodic identifier. In evaluation, the recognition results on emotional speech showed that the rates using proposed method increased more greatly than the existing speech recognizer. For recognition of emotion, on the other hands, four kinds of prosodic parameters such as pitch, energy, and their derivatives were proposed, that were then trained by discrete duration continuous hidden Markov models(DDCHMM) for recognition. In this approach, the emotional models were adapted by specific speaker's speech, using maximum a posteriori(MAP) estimation. In evaluation, the recognition results on emotional states showed that the rates on the vocal emotions gradually increased with an increase of adaptation sample number.

• Genomics & Informatics
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• 제14권1호
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• pp.2-11
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• 2016

The advances in mass spectrometry-based proteomics technologies have enabled the generation of global proteome data from tissue or body fluid samples collected from a broad spectrum of human diseases. Comparative proteomic analysis of global proteome data identifies and prioritizes the proteins showing altered abundances, called differentially expressed proteins (DEPs), in disease samples, compared to control samples. Protein biomarker candidates that can serve as indicators of disease states are then selected as key molecules among these proteins. Recently, it has been addressed that cellular pathways can provide better indications of disease states than individual molecules and also network analysis of the DEPs enables effective identification of cellular pathways altered in disease conditions and key molecules representing the altered cellular pathways. Accordingly, a number of network-based approaches to identify disease-related pathways and representative molecules of such pathways have been developed. In this review, we summarize analytical platforms for network-based protein biomarker discovery and key components in the platforms.

• Journal of information and communication convergence engineering
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• 제7권3호
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• pp.268-274
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• 2009

Human beings can represent state of mind such as psychological state, personality or emotional trouble by the pictures painted on one's own initiative. But in general, it is hard to understand a consulter's unconscious state through one's objective and intentional descriptions only. So one's psychological state and emotional trouble can be understood and cured by color and location information of objects drawn in one's picture. By this reason, a consultant can help and settle a consulter's growth stages of life and emotional trouble through treatment by pictures. In this paper, we proposed a method to find out state of sensitivity by analysis of color and location information represented in a picture and fuzzy inference rules. We applied the proposed method to the states of sensitivity from color information proposed by Alschuler and Hattwick and the psychological states from location information proposed by Grunwald. In the experimental results by the two applications, we verified the proposed sensitivity analysis method is efficient.

• 진공이야기
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• 제1권2호
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• pp.4-8
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• 2014

On this earth, we usually encounter three states of matter: solid, liquid, and gas. Those are the states we experience directly and most often in everyday life. However, if we consider the whole universe, more than 99.99 percent of our visible universe is in plasma state. The earth is in very unusual situation in the universe, and it is great virtue to whole creatures on this planet. In the beginning of the universe, however, there was only plasma. The other stuff came later after then. The Big Bang, beginning of our universe, was dominated by high-temperature plasma. It is where we all came from, and it continues to play a major role not only in our universe but also in various industrial applications of human being.

• 한국수의병리학회지
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• 제1권2호
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• pp.91-96
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• 1997

General steps in the discovery and development of novel drugs in the United States are presented. The first step is the discovery of novel drugs. Brief histories and mechanisms of a few novel drugs in the American market are outlined. In this presentation preclinical animal toxicologic studies (drug safety evaluateion) are emphasized in regard to drug development. When preclinical animal studies have defined the toxicity and the doses at which it occurs an Investigational new Drug Application (IND) is submitted to the Food and Drug Administration (FDA) An IND notifies the FDA the intention to begin testing a novel drug in human subjects.

• 한국문헌정보학회지
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• 제18권
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• pp.157-212
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• 1990

Translation has attained an important role in transmission and maintenance of human culture. As the world gets closer translation is regarded as one of the most useful means to carry knowledge and information through the language barrier. Translations of literary works in particular have been regarded as one of the most valuable means of helping people to understand and cooperate with one another in the interest of world peace. Korea has maintained a very close relationship with the United States of America since she first opened her door to the States in 1882. No one can deny that American has had a strong influence on Korean culture, politics, economics and education through the long close relationship between two countries. This study has been carried to find out how many and what American literary works have been introduced into Korea through translation from 1882 to 1982.

• 제어로봇시스템학회논문지
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• 제12권6호
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• pp.554-560
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• 2006

In this paper, we propose the topological map building method about unknown environment using the ultrasonic sensors. An ultrasonic sensor inherently has the range error due to the specular reflection. To decrease this error, we estimate the obstacle states(position and velocity) using the local minimum sensor values and Jacobian. Estimated states are used to avoid the obstacles and build the topological map similar to the type that human being memorizes an environment. When a mobile robot is faced with three problems(comer way, cross way and dead end), it senses the movable directions using FIS(Fuzzy Inference System). Among these directions, it can select the target direction using binary decision tree(Turn Side Selector). Proposed algorithm has been verified with three simulations and three implementations.

• 대한청각학회지
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• 제23권3호
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• pp.160-166
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• 2019

Lots of neuroimaging and animal studies have revealed that tinnitus and hyperacusis share the same patterns in the bottom up central auditory process. The aim was to identify the abnormal central patterns commonly observed in both tinnitus and hyperacusis in humans. We investigated two cases of normal hearing: a tinnitus patient and a hyperacusis patient. We compared the differences between the severe temporal hyper-activated state (STHS), with spikes, fast beta and gamma frequencies after noise exposure, and the mild temporal hyperactivated state (MTHS), in no sound exposed condition. The power of the gamma band in the two cases was increased in both auditory cortices compared to the other brain regions. Our results of human with normal hearing were the first to identify how tinnitus and hyperacusis caused by sound are abnormally active and how they maintain constant pathological states.

• Journal of Audiology & Otology
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• 제23권3호
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• pp.160-166
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• 2019

Lots of neuroimaging and animal studies have revealed that tinnitus and hyperacusis share the same patterns in the bottom up central auditory process. The aim was to identify the abnormal central patterns commonly observed in both tinnitus and hyperacusis in humans. We investigated two cases of normal hearing: a tinnitus patient and a hyperacusis patient. We compared the differences between the severe temporal hyper-activated state (STHS), with spikes, fast beta and gamma frequencies after noise exposure, and the mild temporal hyperactivated state (MTHS), in no sound exposed condition. The power of the gamma band in the two cases was increased in both auditory cortices compared to the other brain regions. Our results of human with normal hearing were the first to identify how tinnitus and hyperacusis caused by sound are abnormally active and how they maintain constant pathological states.

• 한국사회복지학
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• 제41권
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• pp.119-146
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• 2000

The goals and strategies of welfare-to-work (WTW) policies have been sources of contentious political debate. In the United States, despite 20 years of welfare reform, there remain important differences of opinion regarding how best to design and deliver WTW programs. The proliferation of state and local WTW experiments has led to the identification of two ideal-types of WTW programs: the Labor Force Attachment and Human Capital Development models. Most of the recent policy debate about WTW in America has focused on the relative merits and performance of LFA and HCD. While the Primary goal of the LFA model is for welfare recipients to achieve a rapid transition into work, the HCD model seeks to improve the long-term employability of welfare dependents through education and skill development. LFA policies tend to be strongly outcome-oriented and generally can yield quick results. Their "any job is a good job" philosophy has proved attractive to policy-makers who are anxious to see concrete results in a short-term period. In contrast, the HCD policies do not simply dump welfare dependents at the bottom of the labor market, but aim to secure relatively stable and well-paid jobs. However, these strengths are offset by several practical weaknesses including high unit costs and long-term investment in human capital. In recent years, LFA policies have been increasingly favored by both policy officials and politicians in the United States. The introduction of Temporaray Assistance to Needy Families of 1996 has been accelerating the trend. What is going to happen to welfare recipients? This simple shift to the LFA model, however, will only see an alarming increase of working poor in a near future.