• 대한한의진단학회지
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• 제16권2호
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• pp.59-70
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• 2012

Objectives : Pulse diagnosis by Expert is the only way to classify 8 Constitutions so the study to supplement classifying method by the questionnaire has developed and modified and ECM-32 System has designed in 2010. But analyzing with Decision tree had many nodes and 32 important questions omitted while processing the data. So this study was to classify the 8 constitution patients into 2 groups first and analyze its characters in consecutive order. Methods : The participants of this study were 1027 patients who classified into one of the 8 constitutions according to pulse diagnosis and answered 251 questionnaires in 2010. They were divided into sympathetic nerve acceleration constitution and parasympathetic nerve acceleration constitution and analyzed with decision tree. Results : The reponses of the questionnaire were analyzed with 4 methods of 5 scales interval method from 0 to 5, Na, Low(1,2), Medium(3), High(4,5), average value, Y/N dichotomy. Average Value had no significance. 1. From the 5 scale interval method 6 questionnaires with 7 nodes (F5e, B1d, F7f, F2a, F1b, C4L) were significant. The accuracy was 92.5%. 2. From L, M, H method 7 questionnaires with 7 nodes(F5e, B1d, F7f, F1a, B1c, C4L, P3d) were significant. The accuracy was 92.5%. 3. From Y/N dichotomy 9 questionnaires with 9 nodes( F5e, B1d, F7f, F1a, B1c, C4L, B1b, P1i, B2a) were significant. The accuracy was 93.18%. Conclusions : Based on this study, Yes or No dichotomy method was most significant and categorized among the 4 methods. Unlike previous studies which used interval scale method only, Y/N dichotomy method was more statistically significant with the questionnaire to supplement the method of pulse diagnosis. For further study by analyzing decision tree method in consecutive order, the patients can be divided into 8 Constitutions with higher significance with less questionnaires.

• 한국콘텐츠학회논문지
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• 제9권4호
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• pp.364-371
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• 2009

나관중의 소설 삼국지에 등장하는 인물들에 대한 인간관계 네트워크를 구축하고 분석한 결과, 실제 사회 인간관계 및 사회 네트워크의 특성과 마찬가지로 척도 없는 네트워크 및 계층적 네트워크의 특성을 보여주었다. 지금까지 대부분 네트워크에 관한 연구는 정적인 측면을 중심으로 이루어졌다. 왜냐하면, 네트워크는 고정되어 있는 것이 아니라 시간 및 공간에 따라 다양하게 변화함에도 불구하고 동적인 면을 분석하기 위한 데이터가 충분하지 않기 때문이다. 소설 삼국지는 비교적 짧은 역사 속에서 다양한 등장인물(1,119 노드)과 인물들의 이합집산에 의한 다양한 인간관계(3,604 링크) 연결망을 형성하고 있기 때문에 시간에 따른 동적 네트워크의 분석을 위한 좋은 모델이 될 것이다. 본 연구는 시대적으로 형성되는 네트워크 특성을 분석하고, 주요 등장인물들의 상관관계와 등장인물의 가중치를 분석하여 연결망의 동역학적 특성을 살펴보았다. 따라서 본 연구는 실제 인간관계 및 사회 네트워크나 생명체를 구성하고 있는 분자들의 네트워크에 관한 동역학적 특성을 분석할 수 있는 가능성을 제시하고 있다.

• IMMUNE NETWORK
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• 제1권1호
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• pp.7-13
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• 2001

Currently 18 monoclonal antibodies were approved by FDA for inj ection into humans for therapeutic or diagnostic purpose. And 146 clinical trials are under way to evaluate the efficacy of monoclonal antibodies as anti-cancer agents, which comprise 9 % of clinical trials in cancer therapy field. When considering a lot of disappointment and worries existed in this field during the past 15 years, this boom could be called as resurrection. Antibodies have several merits over small molecule drug. First of all it is easier and faster in development, as proper immunization of the target proteins usually raises good antibody response. The side effects of antibodies are more likely to be checked out in immunohistomchemical staining of whole human tissues. Antibody has better pharmacokinetics, which means a longer half-life. And it is non-toxic as it is purely a "natural drug. Vast array of methods was developed to get the recombinant antibodies to be used as drug. The mice with human immunoglobulin genes were generated. Fully human antibodies can be developed in fast and easy way from these mice through immunization. These mice could make even human monoclonal antibodies against any human antigen like albumin. The concept of combinatorial library was also actively adopted for this purpose. Specific antibodies can be screened out from phage, mRNA, ribosomal library displaying recombinant antibodies like single chain Fvs or Fabs. Then the coding genes of these specific antibodies are obtained from the selected protein-gene units, and used for industrial scale production. Both $na\ddot{i}ve$ and immunized libraries are proved to be effective for this purpose. In post-map arena, antibodies are receiving another spotlight as molecular probes against numerous targets screened out from functional genomics or proteomics. Actually many of these antibodies used for this purpose are already human ones. Through alliance of these two actively growing research areas, antibody would play a central role in target discovery and drug development.

• Archives of Plastic Surgery
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• 제42권4호
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• pp.461-468
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• 2015

Background Functional restoration of the facial expression is necessary after facial nerve resection to treat head and neck tumors. This study was conducted to evaluate the functional outcomes of patients who underwent facial nerve cable grafting immediately after tumor resection. Methods Patients who underwent cable grafting from April 2007 to August 2011 were reviewed, in which a harvested branch of the sural nerve was grafted onto each facial nerve division. Twelve patients underwent facial nerve cable grafting after radical parotidectomy, total parotidectomy, or schwannoma resection, and the functional facial expression of each patient was evaluated using the Facial Nerve Grading Scale 2.0. The results were analyzed according to patient age, follow-up duration, and the use of postoperative radiation therapy. Results Among the 12 patients who were evaluated, the mean follow-up duration was 21.8 months, the mean age at the time of surgery was 42.8 years, and the mean facial expression score was 14.6 points, indicating moderate dysfunction. Facial expression scores were not influenced by age at the time of surgery, follow-up duration, or the use of postoperative radiation therapy. Conclusions The results of this study indicate that facial nerve cable grafting using the sural nerve can restore facial expression. Although patients were provided with appropriate treatment, the survival rate for salivary gland cancer was poor. We conclude that immediate facial nerve reconstruction is a worthwhile procedure that improves quality of life by allowing the recovery of facial expression, even in patients who are older or may require radiation therapy.

• 동서간호학연구지
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• 제14권2호
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• pp.60-66
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• 2008

Background: Communication training in nursing college students is an integral part of the development of their competency in dealing with patients. However, the traditional lecture style of training delivery may not be desirably effective. Purpose: This study investigated the effects of a communication training program utilizing a small group dynamic on the communication competency and human relationships in nursing college students. Methods: One hundred twenty six freshmen in a university in Seoul participated in this study. The instruments of communication competency (Primary Communication Inventory) and human relationships (Relationship Change Scale) were used at the beginning and conclusion of the training period. Eighty-three students from two nursing classes were assigned to the experimental groups and 43 students from other classes were assigned to the control groups. Each of the 11 small groups was composed of 7 or 8 students. The weekly program that ran during the 2007 fall semester from October 1st to December 11th consisted of effective communication strategies including therapeutic communication skills, Johari's window, empathy, active listening, and transactional analysis. Results: The experimental group of students reported significantly greater improvement in communication competencies, specific nonverbal competencies, and human relationships compared with the control group. Specifically, the experimental students demonstrated greater improvement in nonverbal communication competencies and satisfaction, communication, and awareness of human relationships. Conclusions: Small group based communication training can be an effective alternative method of communication education for college nursing students.

• 대한두개안면성형외과학회지
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• 제15권2호
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• pp.70-74
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• 2014

Background: Many options are available to cover a palatal defect, including local or free flaps. The objective of this study was to evaluate the usefulness of palatal mucoperiosteal island flap in covering a palatal defect after tumor excision. Methods: Between October 2006 and July 2013, we identified 19 patients who underwent palatal reconstruction using a palatal mucoperiosteal island flap after tumor excision. All cases were retrospectively analyzed by defect location, size, tumor pathology, type of reconstruction, and functional outcomes. Speech and swallowing functions were evaluated using a 7-point visual analog scale (VAS) score. Results: Among the 19 patients, there were 7 men and 12 women with an age range of 25 to 74 years (mean, $52.5{\pm}14.3$ years). The size of flaps was $2-16cm^2$ (mean, $9.4{\pm}4.2cm^2$). Either unilateral or bilateral palatal island flaps were used depending on the size of defect. During the follow-up period (mean, $32.7{\pm}21.4$ months), four patients developed a temporary oronasal fistula, which healed without subsequent operative. The donor sites were well re-epithelized. Speech and swallowing function scores were $6.63{\pm}0.5$ and $6.58{\pm}0.69$ on the 7-point VAS, indicating the ability to eat solid foods and communicate verbally without significant disability. Conclusion: The palatal mucoperiosteal island flap is a good reconstruction modality for palatal defects if used under appropriate indications. The complication rates and donor site morbidity are low, with good functional outcomes.

• 대한지리학회지
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• 제48권3호
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• pp.366-386
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• 2013

본 연구는 2008년 동절기 가뭄으로 태백시가 단수 및 제한급수를 실시하게 된 과정을 행위자-연결망 이론을 적용하여 분석하였다. 행위자-연결망 이론은 다양한 환경생태문제에 있어 인간 행위자뿐만 아니라 비인간 행위자의 행위와 역할을 강조한다. 2008년 동절기 가뭄이 전국적으로 발생했으나 유독 태백시에서만 88일간 단수 및 제한급수를 실시하게 된 사실은 그 당시 태백시에 배태되어 있었던 인간, 비인간 행위자의 행위와 이들 간의 복잡한 관계, 연결망에 대한 종합적인 분석을 필요로 한다. 연구결과, 태백시청, 한국수자원공사 태백권관리단, 태백시민, 물공급 시설들, 광동댐, 노후한 상수도관, 지형, 토양, 산업 변화, 인구 등 다양한 인간, 비인간 행위자들이 다각적으로 작용하여 기존의 물공급망을 변화시킨 것을 알 수 있었다. 본 연구는 특정 로컬 스케일에서 가뭄재해와 관련된 복잡한 과정을 이해하는데 도움이 되며, 가뭄에 대한 적정한 대책을 강구하는데 도움이 될 것으로 보인다.

• International Journal of Computer Science & Network Security
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• 제22권7호
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• pp.327-331
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• 2022

The article aims at studying the institution of human rights in an ever-evolving world in the context of the interdisciplinary approach. The main scientific method was deduction that allowed examining the specific interdisciplinary approach in relation to the institution of human rights on the global scale. To solve the issue set, it is necessary to study legal foundations and features of the interdisciplinary approach to the institution of human rights in the modern world. The article proves there is no theoretical anthropological understanding of the institution of human rights. It has been concluded that the appeal to anthropological jurisprudence requires the identification of the initial theoretical and methodological principles, parameters and axioms of cognition, the integration of a person into the subject field of legal science, linking jurisprudence with the chosen external environment (philosophy, sociology, theology, etc.), predetermining the existence (understanding) of a person, causing qualitative differences and the structure of subject-methodological phenomena. In addition to the identification of such hypotheses, prerequisites and axioms, the basic method (principle) of cognition and its heuristic potential are also being searched (defined). The terminological designation of the formed subject-methodological phenomenon (legal anthropology, anthropology of law, anthropological approach, etc.) reveals its role in the system of interdisciplinary relations of legal science.

• International Journal of Computer Science & Network Security
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• 제21권12spc호
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• pp.604-610
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• 2021

Human capital is the defining value of the national economy under market conditions. The manifestation of human capital is realized as an intellectual and creative capital, theoretically grounded and proven. The realization of intellectual capital is realized through the research creativity of scientists and researchers, and creative capital is manifested through artists and thinkers. Accordingly, creativity in market conditions forms a separate source of income and is an essential article in the formation of the GDP of the national economy. This research aims to analyze human capital from the perspective of cultural and creative industries. Research methods: systematization; comparative analysis of individual indicators of advanced countries of the world on the training system; statistical, taking into account macroeconomic indicators to assess the level of national creativity potential; system and logical analysis; method of information synthesis. Research results. The structural and quantitative composition of the factors of intellectual and creative capital formation has been systematized. The article proves that the unique properties of human capital, knowledge, creativity, experience and professional skills are the push factors of creativity development of the national economy and provide the priority development of creative and cultural industry that allows generating the added value on the national scale. The functions of creativity in the sphere of cultural industries are highlighted. It is noted that education and creativity of both intellectual and creative capital are the forming basis. The research of the world's advanced countries on the creativity index has pointed out the Netherlands as the leading country in the quantitative measurement of creativity. The economic development factors of the Netherlands were analyzed from the position of economic creativity, which allowed the formation of a two-factor model providing priority development of creativity in the cultural and creative industries.

• 한국사회복지학
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• 제63권1호
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• pp.267-289
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• 2011

본 연구의 목적은 Antonak(1982)이 개발한 SADP and ATDP-O(Scale of Attitudes for Disabled Persons and Attitudes towards Disabled Persons Scale-Original)척도의 타당도를 검증하고 국내에서의 활용방안을 모색하는 것이다. 이를 위해 공무원, 의료인, 교사, 언론인, 장애인복지시설 종사자로 구성된 표적집단과 일반집단으로 구분한 비장애인 500명을 표집하여 척도의 타당도 및 신뢰도를 검증하고, 표적집단과 일반집단 간의 장애인에 대한 태도 차이를 비교하였다. 탐색적 요인분석 결과, 원 척도는 '염세주의-고정관념', '낙관주의-인권', '손상된 성격' 세 가지 차원의 15개 문항으로 정리되었고, 확인적 요인분석 결과, 재구성한 척도의 적합성은 수용할만한 수준(good/reasonable fit)인 것으로 나타났다. 전체척도의 Cronbach's ${\alpha}$ 값은 .8이 넘어 안정적인 신뢰도를 보였으며, DFS(Disability Factor Scale)와는 전반적으로 높은 수준에서 통계적으로 유의미한 상관관계를 나타내 수렴타당도가 확보되었다. 또한 표적집단이 일반집단보다 장애인에 대해 긍정적인 태도를 지닌 것으로 나타났다. 본 연구에서 타당도가 검증된 도구는 다양한 장애유형에 활용할 수 있도록 장애유형별 검증이 필요하며, 척도의 활용으로 장애인에 대한 태도를 개선하기 위한 임상적, 실천적 방안이 모색되어야 할 것이다.