• Journal of the Korean Society of Visualization
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• v.18 no.3
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• pp.96-102
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• 2020

Oral cancer surgery changes the morphologic characteristics of the human upper airway. These changes can affect the flow patterns. In this study, computational fluid dynamics (CFD) simulations with transient solver were performed to numerically investigate the air flows in the human upper airways depending oral cancer surgery. 3D reconstructed models were obtained from 2D CT images of one patient. For the boundary condition, the realistic breathing cycle of human was applied. The hydraulic diameters of cross-sections for post-surgical model are changed greatly along streamwise direction, so these variations can cause higher wall shear stress and flow disturbance compared to pre-surgical model. The recirculation flows observed in the protruding region result in the relatively large pressure drop. These results can be helpful to understand the flow variations after resection surgery of oral cancer.

• Korean Journal of Medicinal Crop Science
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• v.15 no.6
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• pp.411-416
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• 2007

This study was performed to investigate the reduction of toxicity and improvement of anticancer activities from R. sachalinensis by ultra high pressure extracts process. The cytotoxicity on human kidney cell (HEK293) and human lung cell (HEL299) was showed below 20.4% and 21.6% as compare to normal extracts in adding 1.0 $mg/m{\ell}$ concentration. This showed that toxic materials through ultra high pressure processing is broken or degraded. Because bond such as hydrogen bond, electrostatic bond, Van der waals bond, the hydrophobic bond, can be broken by high pressure. The anticancer activity was also increased in over 7% by high pressure processing in A549, AGS, MCF-7 and Hep3B cells. The result showed that extraction by high pressure have low cytotoxicity and high anticancer activity. So, the high pressure extraction technology can play an important role in eruption of new material with high biological activity.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.20-20
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• 2011

It has been known that, under certain conditions, application of low-temperature atmospheric-pressure plasmas can enhance proliferation of cells. In this study, conditions for optimal cell proliferation were examined for various cells relevant for orthopaedic applications. Plasmas used in our experiments were generated by dielectric barrier discharge (DBD) with a helium flow (of approximately 3 litter/min) into ambient air at atmospheric pressure by a 10 kV~20 kHz power supply. Such plasmas were directly applied to a medium, in which cells of interest were cultured. The cells examined in this study were human synoviocytes, rat mesenchymal stem cells derived from bone marrow or adipose tissue, a mouse osteoblastic cell line (MC3T3-E1), a mouse embryonic mesenchymal cell line (C3H-10T1/2), human osteosarcoma cells (HOS), a mouse myoblast cell line (C2C12), and rat Schwann cells. Since cell proliferation can be enhanced even if the cells are not directly exposed to plasmas but cultured in a medium that is pre-treated by plasma application, it is surmised that long-life free radicals generated in the medium by plasma application stimulate cell proliferation if their densities are appropriate. The level of free radical generation in the medium was examined by dROMs tests and correlation between cell proliferation and oxidative stress was observed. Other applications of plasma medicine in orthopaedics, such as plasma modification of artificial bones and wound healing effects by direct plasma application for mouse models, will be also discussed. The work has been done in collaboration with Prof. H. Yoshikawa and his group members at the School of Medicine, Osaka University.

• Korean Journal of Human Ecology
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• v.24 no.5
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• pp.687-700
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• 2015

Lines of non-extension (LoNEs) on torso surface during arm abduction were investigated to provide appropriate location for inserting less-extensible yarns which can be used as seams for design and or clothing pressure variation. As experimental methods, reference points about 3 cm apart were marked on the skin and scanned at 30, $90^{\circ}$ and $135^{\circ}$ arm abduction. Skin deformation was measured by connecting reference points in horizontal, vertical and various angles of diagonal directions. Observation of skin deformation was made within the separated sections of the torso as well as integrated ones to cover the various occasions of design application. LoNEs of front and back torso were provided as mapping lines. Actual compression wear of three types was constructed with different pattern reduction rate at each separated section using LoNEs as boundary cutting lines. Clothing pressure and subjective evaluations of those three compression wear were evaluated by six subjects. LoNEs found in this study were useful as seam lines to differentiate clothing pressure at each part of the body, providing positive wear sensation. It is also expected that LoNEs can be paths for less strechable conductive yarns of IT-integrated upper garments.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.11
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• pp.1174-1185
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• 2012

This study develops tight-fitting upper clothing to measure electrocardiography (ECG) data. Taking into consideration the elasticity of the clothing, we made 4 experimental clothes by applying to each a weft reduction rate of 40%, 50%, 60%, and 70%. The 4 experimental clothes were used to measure resting ECG, exercise ECG, and post-exercise ECG for 4 men in their 20s. We compared clothing pressures using sensors on the human body and on a dressform. Subjective wear sensations of the 4 experimental clothes were evaluated using a subjective 7-point scale (with 7 being most excellent). We measured clothing pressures by using the air type pressure (AMI 3037-2) for upper and lower chest sensors in the developed tight-fitting upper clothing. The lower chest sensor showed that the clothing pressure on a human body and dressform changed consistently as the weft reduction rate decreased. The upper chest sensor showed inconsistent changes in clothing pressure as the weft reduction rate decreased. The wearing-test result for preliminary subjects showed that the lower chest sensor was more stable than the upper chest sensor; therefore, we inserted the sensor at the lower chest position before performing ECG. Except for Subject 4, the resting ECGs were stably measured for 3 subjects (Subject 1, Subject 2, and Subject 3) in all the developed clothes (A clothing, B clothing, C clothing, and D clothing). However, D clothing showed stable ECG values after exercise. The results of the experiment showed that we could measure ECG without difficulty using clothes with a weft reduction rate of 40% when the movement was not intense; however, tight-fitting upper clothing with a weft reduction rate of 70% was necessary to measure exercise ECG and post-exercise ECG values.

• Journal of Families and Better Life
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• v.27 no.5
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• pp.195-206
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• 2009

The main purpose of this study was to examine the effects of maternal achievement pressure and emotional support on adolescents' achievement motivation. A total of 241 adolescents in the second grade of two middle schools in Seoul and their mothers participated in the study, and completed questionnaires on mothers' achievement pressure and emotional support. Adolescents also answered a questionnaire on achievement motivation. Sohn's(1997) Achievement Pressure Scale, Sung's(1993) Social Support Scale and Hermans'(1970) Prestatie Motivatie Scale were used for this survey. Data were analyzed by Pearson's correlation coefficients, t-tests, regressions, and one-way ANOVA with Duncan's multiple range tests. Results showed that maternal achievement pressure and emotional support and adolescents' achievement motivation did not vary as a function of sex. Maternal achievement pressure and emotional support had positive effects on achievement motivation of adolescents, and maternal achievement pressure played a more influential role on the motivation of adolescents than emotional support. Among four groups divided by the level of maternal achievement pressure and emotional support, high/high, high/low, low/high, and low/low, adolescents in the high/high group were perceived to have the highest achievement motivation. Findings suggest that both maternal achievement pressure and emotional support are important in improving adolescents' achievement motivation.

• Nutrition Research and Practice
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• v.11 no.5
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• pp.388-395
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• 2017

BACKGROUND/OBJECTIVES: Although Korean fermented foods contain large amounts of salt, which is known to exacerbate health problems, these foods still have beneficial effects such as anti-hypertension, anti-cancer, and anti-colitis properties. We hypothesized that ganjang may have different effects on blood pressure compared to same concentrations of salt. MATERIALS/METHODS: Sprague-Dawley rats were divided into control (CT), NaCl (NC), and ganjang (GJ) groups and orally administered with 8% NaCl concentration for 9 weeks. The systolic blood pressure (SBP), serum chemistry, $Na^+$ and $K^+$ concentrations and renal gene expressions were measured. RESULTS: The SBP was significantly increased in the NC group compared to the GJ and CT groups. In addition, the $Na^+$ concentration in urine was higher in the GJ and NC groups than the CT group, but the urine volume was increased in the GJ group compared to the other groups. The serum renin levels were decreased in the GJ group compared to the CT group, while the serum aldosterone level was decreased in the GJ group relative to the NC group. The mRNA expression of the renin, angiotensin II type I receptor, and mineralocorticoid receptor were significantly lower in the GJ group compared to other groups. Furthermore, GJ group showed the lowest levels of genes for $Na^+$ transporter in kidney cortex such as $Na^+/K^+$ $ATPase{\alpha}1$ ($NKA{\alpha}1$), $Na^+/H^+$ exchanger 3 (NHE3), $Na^+/HCO_3{^-}$ co-exchanger (NBC), and carbonic anhydrases II (CAII). CONCLUSIONS: The decreased SBP in the GJ could be due to decreased renin and aldosterone levels in serum and increased urinary volume and excretion of $Na^+$ with its transporter gene alteration. Therefore, ganjang may have antihypertensive effect despite its high contents of salt.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.12
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• pp.1099-1110
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• 2020

This research tests the effects of institutional pressures, the use of performance measurement systems and accountability, and moderation effects of human resource capability between institutional pressures and the use of performance measurement systems in the Local Government institutions in Indonesia. The research aims to provide empirical evidence both quantitatively and qualitatively that isomorphism institutional pressures occurred in the scope of implementation of the performance measurement system and accountability in the public sector organizations and to show the importance of human resource capability enhancement in reducing external pressure impact. In addition, it tries to develop the correlation model of institutional pressures, human resource capability, implementation of the performance measurement system, and accountability of public sector organizations. The research used mixed methods with sequential explanatory design. The data collection used surveys and interviews in 209 regency/Special Region of Yogyakarta and Central Java local governments as samples. The research result indicated that the institutionalization process of the performance measurement is influenced by institutional pressures, especially coercive and mimetic pressures. Human resource capability was unable to weaken institutional pressures effects in the performance measurement system implementation. The research also proved that the use of a performance measurement system was able to improve local government institution accountability.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.10
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• pp.1347-1353
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• 2014

It's possible for a human to breathe under water, if dissolved oxygen is effectively used. Fish can stay under water using the gill which extracts dissolved oxygen from water. Water includes small amounts of oxygen, so a human needs larger amounts of water to acquire oxygen enough for underwater breathing. The exhalation gas from a human is another method to get higher amounts of oxygen under water. It mainly composes of oxygen, nitrogen and carbon dioxide. So, if only carbon dioxide is decreased, the exhalation gas has good characteristics for breathing of a human under water. In this paper, composition of the exhalation gas from a human was analyzed using GC. Based on these results, the synthesized gas was prepared and mixed into water which was used for experimental devices to analyze separation characteristics of dissolved gases from water. Experimental devices included a water pump, a hollow fiber membrane module and a vacuum pump. The effects of pressure and water flow on separation characteristics of synthesized gas were investigated. The compositions of gases separated from water using synthesized gas were investigated using GC. These results expect to be applied to the development of underwater breathing technology for a human.

• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.249-254
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• 2021

The study of the impact of weather on viral respiratory infections enables the assignment of causality to disease outbreaks caused by climatic factors. A better understanding of the seasonal distribution of viruses may facilitate the development of potential treatment approaches and effective preventive strategies for respiratory viral infections. We analyzed the incidence of human mastadenovirus infection using real-time reverse transcription polymerase chain reaction in 9,010 test samples obtained from Cheonan, South Korea, and simultaneously collected the weather data from January 1, 2012, to December 31, 2018. We used the data collected on the infection frequency to detect seasonal patterns of human mastadenovirus prevalence, which were directly compared with local weather data obtained over the same period. Descriptive statistical analysis, frequency analysis, t-test, and binomial logistic regression analysis were performed to examine the relationship between weather, particulate matter, and human mastadenovirus infections. Patients under 10 years of age showed the highest mastadenovirus infection rates (89.78%) at an average monthly temperature of 18.2℃. Moreover, we observed a negative correlation between human mastadenovirus infection and temperature, wind chill, and air pressure. The obtained results indicate that climatic factors affect the rate of human mastadenovirus infection. Therefore, it may be possible to predict the instance when preventive strategies would yield the most effective results.