• International conference on construction engineering and project management
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• 2022.06a
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• pp.686-693
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• 2022

Construction is a collaborative endeavor. The complexity in delivering construction projects successfully is impacted by the effective collaboration needs of a multitude of stakeholders throughout the project life-cycle. Technologies such as Building Information Modelling and relational project delivery approaches such as Alliancing and Integrated Project Delivery have developed to address this conundrum. However, with the onset of the pandemic, the digital economy has surged world-wide and advances in technology such as in the areas of machine learning (ML) and Artificial Intelligence (AI) have grown deep roots across specializations and domains to the point of matching its capabilities to the human mind. Several recent studies have both explored the role of AI in the construction process and highlighted its benefits. In contrast, literature in the organization studies field has highlighted the fear that tasks currently done by humans will be done by AI in future. Motivated by these insights and with the understanding that construction is a labour intensive sector where knowledge is both fragmented and predominantly tacit in nature, this paper explores the integration of AI in construction processes across project phases from planning, scheduling, execution and maintenance operations using literary evidence and experiential insights. The findings show that AI can complement human skills rather than provide a substitute for them. This preliminary study is expected to be a stepping stone for further research and implementation in practice.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.231-239
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• 2019

Suppressor of Variegation 3-9 Homolog 2 (SUV39H2) methylates the lysine 9 residue of histone H3 and induces heterochromatin formation, resulting in transcriptional repression or silencing of target genes. SUV39H1 and SUV39H2 have a role in embryonic development, and SUV39H1 was shown to suppress cell cycle progression associated with Rb. However, the function of human SUV39H2 has not been extensively studied. We observed that forced expression of SUV39H2 decreased cell proliferation by inducing $G_1$ cell cycle arrest. In addition, SUV39H2 was degraded through the ubiquitin-proteasomal pathway. Using yeast two-hybrid screening to address the degradation mechanism and function of SUV39H2, we identified translationally controlled tumor protein (TCTP) as an SUV39H2-interacting molecule. Mapping of the interacting regions indicated that the N-terminal 60 amino acids (aa) of full-length SUV39H2 and the C-terminus of TCTP (120-172 aa) were critical for binding. The interaction of SUV39H2 and TCTP was further confirmed by co-immunoprecipitation and immunofluorescence staining for colocalization. Moreover, depletion of TCTP by RNAi led to up-regulation of SUV39H2 protein, while TCTP overexpression reduced SUV39H2 protein level. The half-life of SUV39H2 protein was significantly extended upon TCTP depletion. These results clearly indicate that TCTP negatively regulates the expression of SUV39H2 post-translationally. Furthermore, SUV39H2 induced apoptotic cell death in TCTP-knockdown cells. Taken together, we identified SUV39H2, as a novel target protein of TCTP and demonstrated that SUV39H2 regulates cell proliferation of lung cancer cells.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.2473-2478
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• 2011

The asset management of railway facilities is a total framework for finally supporting a safe and comfortable train service, which includes functions of supporting evaluation of condition and performance of infrastructures, making the decision method of repair or rehabilitation of deteriorated facilities, and lengthening the life cycle of structure through the decision of adequate cost and time of repair or reinforcement. In the range of the asset management, organization, human, the target, and information & data of company are included. Therefore, in this paper, appling the method of asset management analysis to the railway structures, the process of the risk assesment using BRE(Business Risk Exposure) and the basis of consisting optimized renewal decision-making are expressed.

• Korean Journal of Child Studies
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• v.28 no.3
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• pp.163-173
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• 2007

This study analyzed ecological elements of 140 nursery rhymes, stories, and plays in the $6^{th}$ edition of the Guide for Educational Activities and Materials for Kindergarten. The results show that 24 works(17.1%) have ecological elements. Content analysis of ecological elements in these works show works that deal with the side effects of environmental development(3 nursery stories), the cult of nature(1 nursery rhyme), recognition of the eco-cycle(2 nursery rhymes, 4 stories, 2 plays), dignity of life and recovery of human nature(12 nursery stories). On the basis of the results, children's literature containing ecological elements were suggested.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.191-196
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• 2005

Genetic networks are a key to unraveling dynamic properties of biological processes and regulation of genes plays an essential role in dynamic behavior of the genetic networks. A popular characterization of regulation of the gene is a kinetic model. However, many kinetic parameters in the genetic regulation have not been available. To overcome this difficulty, in this report, state-space approach to modeling gene regulation is presented. Second-order systems are used to characterize gene regulation. Interpretation of coefficients in the second order systems as resistance, capacitance and inductance is studied. The mathematical methods for transient response analysis of gene regulation to external perturbation are investigated. Criterion for classifying gene into three categories: underdamped, overdamped and critical damped is discussed. The proposed models are applied to yeast cell cycle gene expression data.

• Journal of the Korean Society of Safety
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• v.22 no.5
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• pp.71-76
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• 2007

Failures of equipments for train control systems are linked directly to extensive damages of human lives or financial losses from the increasing uses of train control equipments utilizing computers. Then safety activities for assuring safety and reliability are needed during the system life-cycle. Risk analysis is important phase to increase safety from determining the risk presented by the identified hazard. In this paper, we investigated several methods for risk estimation of safety activities, and then we drew a comparison between original methods to suggest optimized one in the application to train control systems. In the result of the comparison, we had plan to propose the risk analysis method called Best-Practice(BP) risk method combining advantages of the qualitative and the quantitative analysis. In addition, we attempted to apply the BP-risk method to domestic train control systems handling in Korea.

• IE interfaces
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• v.1 no.1
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• pp.85-99
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• 1988

High Touch product is characterized by shorter life cycle together with specification/integration of existing function in order to capitalize the rapidly emerging high technology. R & D strategy for a development of High Touch product generally emphasizes two aspects ; Industrial Design (ID) and Ergonomic Design (ED). However, working knowledge on ED of a systematic identification of potential High Touch products is not readily available. The purpose of this study was three-folded : (1) To emphasize the fact that greater efforts should be geared to ED in High Touch design ; (2) To develop an ergonomic approach based on analysis of implicit human needs that identifies potential area of High Touch ; (3) To bubble with new and probable High Touch products in home electronics that actually demonstrate the validity of this study.

• Proceedings of the ESK Conference
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• 1996.10a
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• pp.153-159
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• 1996

Usability evaluation can be valuable tool for analyzing and improving computer software. Various usability evaluation methods have been developed in the fields of human-computer interaction and software ergonomics. Although there are several useful methods available, designers or engineers engaged in usability evaluations should really select the most suitable methods for each specific system being evaluated. Even different systems within the same organization may require different evaluation methods to maximize the quality of the data obtained from each evaluation. In this paper, the taxonomy of evaluation methods based on the development life cycle is presented and comparative analysis between methods is performed. In addition, the implications for selecting appropriate usability methods and using them collectively are discussed.

• International Journal of Human Ecology
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• v.14 no.2
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• pp.69-78
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• 2013

This study analyzed the changes in household consumption expenditure of retired households using Korean panel data. We compared the pre and post retirement-consumption levels in different consumption categories using panel data. Paired t-test showed that changes in the consumption patterns before and after retirement were not significant except for the households in the third net worth quartile. Analyzing the effect of retirement on the level of household consumption expenditure, this study found that the effect of retirement was not significant in overall, although retirement had a negative effect on the level of consumption expenditure among households in the lowest net worth distribution. Understanding changes in consumption patterns of retiring households provides important information to design social security policies.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.12 no.4
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• pp.29-35
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• 2003

The rotating machineries always generate harmonic frequencies of their own rotating speed, and increment of vibration amplitude affects to the equipments which connected to the vibrational source and causes industrial calamities. The life cycle of equipments can be extended and damages to the human beings could be prevented by identifying the cause of malfunctions through prediction of the increment of vibration and records of vibrational history. In this study, therefore, diagnostic expert algorithm for the centrifugal pump is developed by integrating fuzzy inference method and signal processing techniques. And the validity of the developed diagnostic system is examined via various computer simulations.