• 한국환경성돌연변이발암원학회지
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• 제21권2호
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• pp.106-112
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• 2001

In view of the effect of factor Ⅶ as a risk factor for essential hypertension, we investigated the length (I/D) polymorphism at position 323 promoter region and exon 8-Msp I RFLP of the human factor Ⅶ gene in the Korean patients with essential hypertension and normal controls. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between two polymorphic sites. The Msp I RFLP and I/D polymorphism were also significantly associated with plasma triglyceride (TG) levels. Therefore, our results suggest that the significant association between two genetic variations in the human factor Ⅶ gene and plasma TG level may reflect the potential role of human factor Ⅶ gene as one of the genetic components for cardiovascular risk.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 후기학술대회논문집
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• pp.108-109
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• 2005

The aim of Port State Control(PSC) system is recognized as a proficient mechanism in preventing coastal traffic accident and protecting marine environment. Recently, PSC system is focused on human factor of International Maritime Convention, especially ILO and STCW Convention by considering many accidents resulted from human factor. Therefore, we have to understand of Consolidated Maritime Labour Convention which describes employment conditions and social welfare policy, the rights about the lowest wages, the overdue wages, the unemployment protection. a disaster reward, etc and STCW Convention which describes standards of training, certification and watchkeeping for seafarers. The aim of this study is to recognize inspection points about human factor of these Conventions. .

• 디자인학연구
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• 제16권3호
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• pp.81-90
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• 2003

본 연구의 목적은 인간의 본질인 신체적ㆍ정신적 특성에 따른 제품의 새로운 분류 방식을 제시하고 이를 통해 제품의 미래를 이해하는데 있다. 연구의 목적을 위해 인간과 제품의 관계 특성을 과거와 미래를 통해 비교 분석하였고, 이 과정에서 제품을 발생학적으로 분류할 수 있었다. 연구는 그 결과를 '신체적 제품'의 미래와 '정신적 제품'의 미래로 나타냈다.

• Nuclear Engineering and Technology
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• 제55권10호
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• pp.3628-3638
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• 2023

This paper uses 135 Licensed Operator Event Reports (LOER) from Chinese nuclear plants to analyze how safety culture affects unsafe behaviors in nuclear power plants. On the basis of a modified human factors analysis and classification system (HFACS) framework, structural equation model (SEM) is used to explore the relationship between latent variables at various levels. Correlation tests such as chi-square test are used to analyze the path from safety culture to unsafe behaviors. The role of latent error is clarified. The results show that the ratio of latent errors to active errors is 3.4:1. The key path linking safety culture weaknesses to unsafe behaviors is Organizational Processes → Inadequate Supervision → Physical/Technical Environment → Skill-based Errors. The most influential factors on the latent variables at each level in the HFACS framework are Organizational Processes, Inadequate Supervision, Physical Environment, and Skill-based Errors.

• 대한안전경영과학회지
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• 제16권2호
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• pp.1-9
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• 2014

This study tried to propose plan to prevent human error of railroad driver among human error of railroad worker which takes great share in railroad accident. For this, in order to maintain correlation between the accident actually occurred after the opening of high-speed railroad and experience of accident that did not happened, survey on respondent was analyzed by conducting survey on KTX captain who is working in driving work of high-speed railroad, and instruction management team manager who manages KTX captain and captain. This thesis classified the factors by human factor, job factor, environment factor, organization factor, and established human error management model by comparing and analyzing how each factors have spatial interrelations with a railroad accident. The purpose of this study is to contribute to make safe railroad, and reliable railroad by preventing human error accident by minimizing human error of high-speed railroad drivers, and improving driving workers to cope accurately and fast with irregularities through various institutional improvement, improvement of driving facilities, improvement of operating room environment, and improvement of education system.

• Nuclear Engineering and Technology
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• 제52권1호
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• pp.87-100
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• 2020

Performance shaping factors (PSFs) in a human reliability analysis (HRA) are one that may influence human performance in a task. Most currently applicable HRA methods for nuclear power plants (NPPs) use PSFs to highlight human error contributors and to adjust basic human error probabilities (HEPs) that assume nominal conditions of NPPs. Thus far, the effects of PSFs have been treated independently. However, many studies in the fields of psychology and human factors revealed that there may be relationships between PSFs. Therefore, the inter-relationships between PSFs need to be studied to better reflect their effects on operator errors. This study investigates these inter-relationships using two data sources and also suggests a context-based approach to treat the inter-relationships between PSFs. Correlation and factor analyses are performed to investigate the relationship between PSFs. The data sources are event reports of unexpected reactor trips in Korea and an experiment conducted in a simulator featuring a digital control room. Thereafter, context-based approaches based on the result of factor analysis are suggested and the feasibility of the grouped PSFs being treated as a new factor to estimate HEPs is examined using the experimental data.

• Journal of Periodontal and Implant Science
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• 제26권2호
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• pp.429-447
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• 1996

Transforming growth factor $-{\beta}$ is one of the polypeptide growth factors that mediate the activity of mesenchymal cells and regulate wound healing process via cell proliferation, migration and extracellular matrix formation. The purposes of this study is to evaluate the effects of transforming growth factor $-{\beta}$ on the protein synthetic activity of human periodontal ligament cells and human gingival fibroblasts. The cells which were prepared were primary cultured gingival fibroblasts and periodontal ligament cells from humans, and the fourth or sixth subpassage were used in the experiments. Cells were seeded and at a confluent state, 0, 0.5, I, 2.5, 5, 10 ng/ml $TGF-{\beta}$ and $2{\mu]Ci/ml\;[^3H]$ proline were added to the cells and cultured for 24 hours. Then, 1 and 5 ng/ml concentrations were selected and added to confluent cells and cultured for 24 and 48 hours. They were labeled with $2{\mu}Ci/ml\;[^3H]$ proline for 24 hours and a collagen assay was done by the Peterkofsky and Diegelman method. The results were presented as the mean disintegration per minute (dpm) per well and S.D. of four determinations, The results were as follows. : The total protein, collagen and noncollagenous protein synthesis in periodontal ligament cells and gingival fibroblasts were increased dose- dependently by transforming growth factor-p to 2.5-5 ng/ml concentration and decreased at 10 ng/ml concentration. The percent of collagen was slightly changed according to the concentration of transforming growth factor-po The effect of transforming growth $factor-{\beta}$ was not specific for collagen synthesis since it increased the total, noncollagenous and collagenous protein, simultaneously. In the comparison of protein synthetic activity between the human periodontal ligament cells and human gingival fibroblasts, the human gingival fibroblasts had higher activities than the human periodontal ligament cells at all times and concentrations of $TGF-{\beta}$. In the comparison of protein synthetic activity between the 24 hour effect and the 48 hour effect of $TGF-{\beta}$, the 48 hour cultured cells' synthetic activity decreased more than the 24 hour cultured cells at human periodontal ligament cells and human gingival fibroblasts. In conclusion, $TGF-{\beta}$ has important roles in the stimulation of protein synthesis in human periodontal ligament cells and human gingival fibroblasts. Thus, it may be useful for clinical application in periodontal regenerative procedures.

• BMB Reports
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• 제38권6호
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• pp.646-649
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• 2005

Human neuronal growth inhibitory factor (GIF), a metalloprotein classified as metallothionein-3, is specifically expressed in mammal central nervous system (CNS). In these Studies the specific antibody to human GIF was prepared and used to search the epitope of human GIF by enzyme-linked immunosorbent assay (ELISA) and sequence comparison. The result of ELISA showed the epitope of human GIF may locate on a octapeptide (EAAEAEAE) in the $\alpha$-domain of human GIF, and the result of nerve cell culture indicated that the biological activity of GIF may be affected by the specific antibody.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 ITC-CSCC -3
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• pp.1886-1888
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• 2002

Non-verbal information plays an important role not only in human-to-human communications but also in human computer interaction. In this paper, we examine effects of human-like agent's primitive movements on user's impression, where the human-like agent's primitive movements include eye, mouth, and head. SD (Semantic Differential) method was used for evaluation, and two factors were extracted as a result of the factor analysis. It is found that the first factor influenced the user's impression particularly.

• 대한인간공학회지
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• 제30권4호
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• pp.491-494
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• 2011

Objective: to improve agricultural working environment using tools and equipments. Background: most existing tools currently used, in fact, are discrepant from human factor guidelines so that they are still exposed to the musculoskeletal disease. Method: the provided tools and equipments are mostly designed considering human factor engineering or usability engineering in a way to avoid musculoskeletal disease. Results: propose the top-down procedure and usability engineering steps to evaluate them for the system design suitability. Conclusion: apply them conveniently into rural environment to help farmers working environment.