• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3305-3308
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• 2013

Background: The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients. In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate. The human papillomaviruses (HPVs) are a family of sexually transmitted viruses which have been implicated in the aetiology of cervical cancer and several other malignancies. This study evaluated the frequency of HPV infection in individuals with prostatic disease in Iran. Materials and Methods: The study included formalin fixed paraffin- embedded tissue samples of 196 primary prostate cases, including 29 PCa and 167 BPH samples. HPV DNA was purified and amplified through MY09/MY11 and GP5+/GP6+ primers with nested PCR. All patients were interviewed using a questionnaire to collect demographic information. Results: Nested PCR showed that HPV DNA was found in 17.2 percent of PCa samples and 4.8 percent of BPH samples (not significant). Conclusions: Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma. Further studies are required to elucidate any roles of HPV infection in prostatic disease.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권6호
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• pp.530-543
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• 2006

Adeonoid cystic carcinoma (ACC) is one of the most common malignant tumors of salivary glands. It is characterized by a relentless regrowth especially around nerve tissues and a high rate of hematogenous distant metastasis. Clinically most deaths from salivary ACC are caused by delayed lung metastases that are resistant to conventional chemotherapy. So, knowledge of cellular and molecular properties that influence the dissemination of metastatic tumor cells, is important for new treatment strategies of metastatic lesions. We determined expressions of angiogenic signaling molecules microvessel density (MVD) using surgical specimens of human salivary ACC. Protein expressions of vascular endothelial growth factor (VEGF), VEGF receptor (VEGFR)-2, activated VEGFR-2, and human CD31 were assessed in 20 cases of salivary ACC by immunohistochemical staining. Most of the tumors, especially ACC with a tubulocribriform pattern, were positive for antibodies of VEGF, VEGFR-2, and activated VEGFR-2. The overall percentages of the 20 specimens expressing VEGF, VEGFR-2, activated VEGFR-2 were 90, 95, and 95%, respectively. Immunoreactivities of the biomarkers in salivary ACC were higher than those in normal salivary gland. Furthermore, immune-related cells as well as tumor cells expressed VEGF/VEGFR-2. Microvessel density of salivary ACC was higher than that of normal salivary gland (P<0.05). Taken together, angiogenic signaling molecules are actively expressed in salivary ACC. And we suggest that these molecules may have critical role in the hematogenous spread of salivay ACC, which has a propensity for delayed lung metastasis. Therefore, these biomarkers can be molecular targets for therapy of metastasis of salivary ACC.

• 한국실내디자인학회논문집
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• 제19권3호
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• pp.38-45
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• 2010

Surface has been an important issue in contemporary architecture. That originates in structural freedom of surface since the end of modern architecture and the current stream of surface becoming an identity of building. Development of digital-media has brought a great change to our society in general. Digital-media is characterized by use of digital-information and interactive communication. Digital-media has been applied on surface in contemporary architecture lately. It is a purpose of the study to analyze the characteristics of digital-media application on surface based on the related characteristics of installation art. The categories and the contents for the frame of case analysis were arranged through document research. The foreign and domestic cases of digital-media application were analyzed based on the frame of analysis. Digital-media, which is installed on surface, is interacted with human and surroundings. It enhances emotional communication between human and architecture. Surface is not any more a simple fixture but an interactive creature. It makes surface more dynamically and fluidly that the course of light and human movement affect on digital-media. Surface itself is also turned into an object of art. It reflects the interweaving characteristics between contemporary architecture and installation art. It was analyzed through the study that emotional level of people is the important issue shared in digital-media application on surface and installation art. The complementary relationship between surface of contemporary architecture and installation art can be manipulated by the application of digital-media on surface.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.445-449
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• 2009

Purpose: A successful surgical treatment for a wide alveolar cleft with bone graft is difficult to achieve due to several factors such as the limitation of gingivoperiosteal flap, the presence of large scar tissues, and the poor blood circulation. To overcome these problems, alveolar distraction osteogenesis using Liou alveolar distraction device was applied. We analyzed the consequences of this surgical treatment. Method: Between 2006 January and 2007 August, we have conducted analysis on the methods and consequences of Liou alveolar distraction osteogenesis for 6 patients. The age of patients was 12 years and 6 months in average. The follow up period was 19 months in average. The Reverse L osteotomy followed by the placement of the Liou alveolar distraction device was performed. After serial distraction, the distractor was removed after 5 months of the process of osteogenesis, and the result was analyzed using the computed tomography and the x-ray films of the alveolar bone and the teeth. Results: The alveolar cleft with 12.5 mm in average width was filled with 8.5 mm of newly formed bone tissue in average width after 5 months of osteogenesis. Among the 6 cases, 5 required the additional bone graft and 1 case only required the gingivoperioplasty. The newly formed bone tissues did not show any signs of bone resorption. However, a considerable degree of teeth displacement was shown. Conclusion: For the alveolar cleft too wide to be reconstructed by a general bone graft, it is strongly recommended to perform the reverse L osteotomy of the cleft side with Liou alveolar distraction device to initiate the alveolar osteogenesis. However, the migrated teeth showed some degree of relapse, thus, the orthodontic treatment is essential following the distraction osteogenesis treatment.

• Parasites, Hosts and Diseases
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• 제26권3호
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• pp.199-206
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• 1988

경북 청송군 일부 하천 유역에서 호르텐스극구흡충의 유행양상을 조사하는 한편 이 흡충 의 인체감염시 나타나는 임상적 및 기생충학적 특성을 관찰하였다. 주민 263명을 대상으로 실시한 검편에서 호르텐스극구흡충란 양성자는 59명 (22.4%)이었으며, 제2중간숙주인 담수어 조사에서는 미꾸리, 얼룩동사리 및 몰개로부터 호르텐스극구흡충의 피낭유충이 검출되었다. Pragiquantel 투여 후 시행한 충체 수집검사에서 감염자 1인당 1∼649(평균 51)마리의 충체가 검출되었고, 혈액학적 검사에서 호산구가 l∼24%(평균 6%)로 나타났다. 개인별 충란 및 충체검출 성적을 토대로 할 때, 충체 마리당 1일 평균 산란수는 1,478개로 계산되었다. 따라서 이 연구 결과, 경북 청송군 일부 하천 유역이 호르텐스극구흡충의 고도 유행지임을 알 수 있었다.

• 대한미생물학회지
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• 제18권1호
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• pp.59-65
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• 1983

To investigate the effects of placental serum to in vitro culture of the normal human lymphocytes the peripheral blood lymphocytes were isolated by ficoll-hypaque separation method in 20 healthy human adults. The blast transformation respone of lymphocytes to mitogens were observed by stimulation with PHA($25{\mu}g/ml$) and Con A($25{\mu}g/ml$) using RPMI 1640 media containing 20% placental serum(PS), tetal calf serum(FCS), or humans AB serum(AB). And one-way mixed lymphocyte culture test was performed between these unrelated person compounded into stimulators and responders to investigate the effect of placental serum. The following results were obtained. 1. In 20 experimental cases, these were no significant diffenence between FCS, AB, and PS in untreated control cultures. 2. In PHA-treated cultures, whereas the blast transformation rate of the FCS groups and AB groups were $40.8{\pm}4.3%$ and $44.6{\pm}4.3%$ respectively, that of PS groups were $21.7{\pm}3.4%$, Similar results were obtained in Con A-meated cultures. Therefore, placental serum inhibited the mitogenic response of lymphocytes significantly. 3. In MLC tests, stimulation index of the FCS groups and AB groups were $18.5{\pm}3.5$ and $20.1{\pm}3.3$ respectively. But placental serum inhibited MLC response of lymphocytes significantly($7.4{\pm}1.9$).

• 한국산업정보학회논문지
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• 제23권5호
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• pp.145-157
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• 2018

본 연구는 항공객실서비스의 인적서비스 역량에 따른 국내 항공사의 서비스 실패 사례를 분석하여 서비스 회복 방안 및 항공객실서비스품질을 향상시킬 수 있는 대응절차와 전략방안을 제시하였다. 항공사의 물적서비스와 인적서비스에 따른 서비스 실패는 고객의 이탈을 가져올 수 있고 기업의 수익성 향상에 부정적인 영향을 미칠 수 있다. 그러므로 고객만족을 위해 서비스 실패 상황이 발생 시 신속한 대처를 통한 회복의 노력을 기울여 고객 불만이 재발되지 않도록 해야 한다. 특히 항공객실승무원에 의한 서비스 역량은 고객 평가와 밀접하게 연관되어 있으며, 객실서비스 회복을 위한 인적서비스 역량은 고객만족도에 매우 긍정적인 영향력을 가지고 있다. 따라서 항공객실 서비스의 고객 불만사례 원인을 분석함으로써, 서비스 실패가 발생했을 때 효과적이고 신속한 객실 승무원의 대응전략을 찾을 수 있다. 이를 통하여 기업은 고객의 기대가치를 회복하고 고객과 지속적이고 우호적인 관계를 유지함으로써 고객충성도를 이끌어낼 수 있다.

• 한국생활과학회지
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• 제17권5호
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• pp.989-999
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• 2008

The purpose of this study was to supply the basic data for the plan of the storage space in the kitchen by investigating the actual condition of the use and residents' satisfaction. The questionnaires were distributed to 136 families of the local apartment in South Chung-Cheong Province of Korea. The results were summarized as follows; first, among the furniture for storage, the upper and lower space have been installed in every furniture. The general tablewares were stored in the upper part of the kitchen and the frequently used goods for cooking were largely stored in the lower part. Second, in the method of reforming the kitchen space, it showed highest figure in case of purchasing the shelf and there were many cases of storing things by using the subsidiary storage furniture and boxes and it came to the conclusion that the housewives have a tendency to solve the storage problem by using the less expensive, simple and passive ways. Third, in the degree of satisfaction for the space for storage, it showed that the respondents were a little bit dissatisfied with the size of storage space, the position of furniture for storage, the convenience for using and the storage rapacity. Among the furniture for storage in the kitchen, the degree of satisfaction for the upper and lower parts was a little bit low, but it is higher for the others. For the plan of storage space, the aesthetic appreciation reflects visually being in order was considered to be the important factor.

• 만화애니메이션 연구
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• 통권28호
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• pp.101-124
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• 2012

<아바타>(Avatar, 2009)의 성공 이례로 세계 영화 및 미디어 시장에는 큰 변혁이 일어났다. 3D 입체 영상에 대해 새로운 산업적 가능성이 예측되었고 다양한 미디어 플랫폼에서 엄청난 제작지원이 이루어지기 시작했다. 전 세계의 가정용 전자제품 TV 시장동향을 보면 하드웨어 분야에서는 국내의 기술은 상당히 높은 수준의 산업적 부가가치를 창출하고 있다. 하지만 애니메이션 분야에서의 3D 입체에 대한 효과적이고 체계적인 제작 파이프라인과 사례 분석이 부족한 현실이다. 3D 애니메이션 <뽀롱 뽀롱 뽀로로>를 입체 애니메이션으로 제작한 사례분석을 통해 적합한 3D TV 입체 애니메이션 제작 파이프라인을 구축하고자 한다. 3D 입체감을 높이기에 적합한 연출적 요소와 공학적 요소 특히, 주요 관객인 아이들에게 맞는 휴먼 팩터(human factor)와 3D Sweetening 등을 함께 적용함으로써 기존의 입체 콘텐츠와 차별화하고자 한다. 이는 차세대 애니메이션의 새로운 교두보를 확보하고 한국 애니메이션의 국제적인 경쟁력을 키우는데 큰 역할을 할 것이다.

• Spatial Information Research
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• 제22권6호
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• pp.45-54
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• 2014

최근 안전취약계층을 상대로 한 범죄가 증가함에 따라 사회적 약자를 위한 안전망 구축에 대한 관심이 증가하고 있다. 이를 위하여 사회안전망 구축 연구성과의 지속적인 실증을 위한 테스트베드를 필요로 하고 있다. 그러나 기존의 지능형국토정보기술혁신사업이나 U-Eco City R&D 사업 등의 테스트베드는 연구개발 성과물을 테스트베드에 적용하여 효과를 검증하는 단계에만 머물러 사업 종료 후 기술의 사업화 및 테스트베드의 지속적인 운영 관리 측면에는 미흡한 점이 많았다. 따라서 R&D성과물에 대한 지속가능한 운영 관리체계 및 제도가 필요한 실정이다. 본 연구는 기존의 테스트 베드 사례와 방범 및 범죄 예방 연구사례를 토대로 지능형 방범 실증지구의 개념을 정립하고, 실증지구 선정기준에 대해 제시하였다. 객관적인 평가기준을 통해 선정된 실증지구는 연구기간 이후에도 지속적인 운영이 가능하고, 시민들의 안전한 삶에 기여하는 실증지구의 표준모델을 확립할 수 있을 것으로 사료된다.