• Journal of Internet Computing and Services
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• v.20 no.2
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• pp.101-108
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• 2019

Workflow management systems (WfMSs) automate and manage workflows, which are implementations of organizational processes operated in process-centric organizations. In this paper, wepropose an algorithm to discover temporal work transference networks from workflow execution logs. The temporal work transference network is a special type of enterprise social networks that consists of workflow performers, and relationships among them that are formed by work transferences between performers who are responsible in performing precedent and succeeding activities in a workflow process. In terms of analysis, the temporal work transference network is an analytical property that has significant value to be analyzed to discover organizational knowledge for human resource management and related decision-making steps for process-centric organizations. Also, the beginning point of implementinga human-centered workflow intelligence framework dealing with work transference networks is to develop an algorithm for discovering temporal work transference cases on workflow execution logs. To this end, we first formalize a concept of temporal work transference network, and next, we present a discovery algorithm which is for the construction of temporal work transference network from workflow execution logs. Then, as a verification of the proposed algorithm, we apply the algorithm to an XES-formatted log dataset that was released by the process mining research group and finally summarize the discovery result.

• Entomological Research
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• v.48 no.6
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• pp.540-549
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• 2018

Climate change due to global warming and changes in land use increase the development time and distribution, as well as the abundance, of mosquitoes, thereby negatively affecting human life and health. In this study, we investigated the habitat characteristics of mosquito occurrence sites in Danwon-gu, Ansan city, Korea, based on a daily record of civil pest complaints lodged at the Danwon-gu Community Health Center. We considered two types of factors (natural and artificial) known to affect mosquito occurrence. We confirmed a total of 554 cases of mosquito occurrence from March 2014 to August 2017. The total study area was $49.11km^2$, with urban areas constituting the largest proportion. Additionally, we investigated habitat preferences of mosquitoes in terms of terrain factors; generally, mosquitoes occurred at low elevations and on low slopes. Regarding the preference of oviposition sites, mosquitoes occurred at higher rates near streams and crops lands. The rate of mosquito occurrence tended to increase in areas with dense human populations. Regarding climatic factors, the rate of mosquito occurrence increased in areas with high temperature and low precipitation.

• Biomedical Science Letters
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• v.27 no.2
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• pp.105-110
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• 2021

Short Tandem Repeats (STR) analysis which characterized by genetic polymorphism has been widely used in the forensic genetic fields. Unfortunately, mutation occurred in various STR loci could make it difficult to interpret STR data. Thus, the mutation rate of STR loci plays an important role for the data interpretation in human identification and paternity test. To verify the mutation of the STR loci in the Korean population, 545 trio sets (father, mother, and child) were analyzed with two commercial STR kits that include the 23 autosomal STR loci (D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, D5S818, CSF1PO, D7S820, D8S1179, D10S1248, TH01, D12S391, VWA D13S317, D16S539, D18S51, D19S433, D21S11, D22S1045, SE33, Penta E and Penta D). As a result, 36 mutations were observed in 14 STR loci. The types of mutation were also classified by the increase or decrease of the alleles. The overall mutation rate was 1.4×10^-3, and the paternal mutation rate was four times higher than that of the maternal. This study will provide more detailed criterion for human identification by the mutation rate of STR loci in the Korean population.

• Biomolecules & Therapeutics
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• v.29 no.3
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• pp.268-272
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• 2021

Novel coronavirus (SARS-CoV-2) has caused more than 100 million confirmed cases of human infectious disease (COVID-19) since December 2019 to paralyze our global community. However, only limited access has been allowed to COVID-19 vaccines and antiviral treatment options. Here, we report the efficacy of the anticancer drug pralatrexate against SARS-CoV-2. In Vero and human lung epithelial Calu-3 cells, pralatrexate reduced viral RNA copies of SARS-CoV-2 without detectable cytotoxicity, and viral replication was successfully inhibited in a dose-dependent manner. In a time-to-addition assay, pralatrexate treatment at almost half a day after infection also exhibited inhibitory effects on the replication of SARS-CoV-2 in Calu-3 cells. Taken together, these results suggest the potential of pralatrexate as a drug repurposing COVID-19 remedy.

• Journal of Veterinary Clinics
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• v.39 no.2
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• pp.59-64
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• 2022

A dog aged two years and seven months and a cat aged seven years were referred owing to fractures of long bones. Preoperative radiographs revealed comminuted bone fractures close to joints. Conventionally, long-bone fractures are treated using intramedullary pins, plate and screw systems, or an external fixator system. In cases of non-reducible fractures, various graft materials have been used in fracture treatments to stimulate bone repair. Here, recombinant human bone morphogenetic protein-2 (rhBMP-2) and a collagen membrane were applied. Four weeks after surgery, fractured bone fragments began to unite and the bone union was observed using radiography four months after surgery. No complications occurred related to grafted materials. We successfully applied rhBMP-2 and collagen membranes in two different species to support the healing process of comminuted fractures, according to the concept of guided bone regeneration.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.369-375
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• 2022

The educational environment of the era of age of uncertainty and human and disaster, where nothing is predictable, so it is bringing about many changes. The purpose of this study is to suggest the implications of Integrative arts therapy in the educational field of unpredictable times as a way to move the minds of people living in various educational changes. As for the research method, the characteristics of the integrative arts therapy shown in the previous studies were examined through the literature method, and then through the cases in the modern education environment practiced we propose three things. First, in the field of university education, students should have an integrative arts therapy approach in terms of teaching methods, and also, second, in order to recover from failure and frustration, continuous gratitude sharing training to discover and acknowledge positivity in the situation by changing perspectives should improve students' self-esteem and self-efficacy. Third, professors should play the role of facilitators and also coaches in knowledge transfer. Therefore the coaching process should be integrated into the process of sustainable education when the integrative arts therapy is approached from the pedagogical curriculum.

• Journal of Fashion Business
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• v.26 no.6
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• pp.32-46
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• 2022

The purpose of this study is to explore a three-dimensional (3D) simulation of skirt shape concepts by manipulating circumferences and lengths via parametric design in the fashion design concept stage. This study also intends to propose a modeling method that can judge and transform the shape through immediate parameter adjustment. We looked at cases that utilized parametric design in other fields of fashion design, reviewed and analyzed the variables used in each study, and constructed parameters suitable to implement skirt fashion design. The traditional design elements required for skirt design, namely waist and hip circumferences, were set as variables in this study. The parametric design was developed to generate ideas of two skirt silhouettes (tight and flared) and three lengths (mini, knee-length, and maxi). To apply the skirt design implemented through variables to the actual 3D human shape, the shape data of women in their 20s and 30s were randomly selected from the 5th human data of Size Korea. Skirt design silhouette modeling was performed by adjusting the variable values according to body type. Parametric design has the potential to help develop design ideas in the field of fashion design, considering the method and characteristics of parameters of the variety of variables and rapid modification. Furthermore, if systematic research on variables and options among fashion design elements is conducted, the possibility of converging them into customization or co-design fashion design processes could be confirmed.

• Restorative Dentistry and Endodontics
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• v.48 no.2
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• pp.20.1-20.13
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• 2023

This mini-review was conducted to present an overview of the use of exosomes in regenerating the dentin-pulp complex (DPC). The PubMed and Scopus databases were searched for relevant articles published between January 1, 2013 and January 1, 2023. The findings of basic in vitro studies indicated that exosomes enhance the proliferation and migration of mesenchymal cells, as human dental pulp stem cells, via mitogen-activated protein kinases and Wingless-Int signaling pathways. In addition, they possess proangiogenic potential and contribute to neovascularization and capillary tube formation by promoting endothelial cell proliferation and migration of human umbilical vein endothelial cells. Likewise, they regulate the migration and differentiation of Schwann cells, facilitate the conversion of M1 pro-inflammatory macrophages to M2 anti-inflammatory phenotypes, and mediate immune suppression as they promote regulatory T cell conversion. Basic in vivo studies have indicated that exosomes triggered the regeneration of dentin-pulp-like tissue, and exosomes isolated under odontogenic circumstances are particularly strong inducers of tissue regeneration and stem cell differentiation. Exosomes are a promising regenerative tool for DPC in cases of small pulp exposure or for whole-pulp tissue regeneration.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.88-90
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• 2021

This paper introduces a method for extracting subtitles from lecture videos through a Korean morpheme analyzer and classifying video categories according to the extracted morpheme information. In some cases incorrect information is entered due to human error and reflected in the characteristics of the items, affecting the accuracy of the recommendation system. To prevent this, we generate a keyword table for each category using morpheme information extracted from pre-classified videos, and compare the similarity of morpheme in each category keyword table to classify categories of Lecture videos using the most similar keyword table. These human intervention reduction systems directly classify videos and aim to increase the accuracy of the system.

• Annual Conference on Human and Language Technology
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• 2020.10a
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• pp.76-81
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• 2020

법률 전문 지식이 없는 사람들이 법률 정보 검색을 성공적으로 하기 위해서는 일반 용어를 검색하더라도 전문 용어가 사용된 법령정보가 검색되어야 한다. 하지만 현 판례 검색 시스템은 사용자 선호도 검색이 불가능하며, 일반 용어를 사용하여 검색하면 사용자가 원하는 전문 자료를 도출하는 데 어려움이 있다. 이에 본 논문에서는 일반용어가 사용된 질의문과 전문용어가 사용된 판례를 자동으로 연결해 주고자 하였다. 질의문과 연관된 판례를 자동으로 연결해 주기 위해 전문용어가 사용된 전문가 답변을 바탕으로 문서분류에 높은 성능을 보이는 Doc2Vec을 이용한다. Doc2Vec 문서 임베딩 기법을 이용하여 전문용어가 사용된 전문가 답변과 유사한 답변을 제안하여 비슷한 주제의 답변들끼리 분류하였다. 또한 전문가 답변과 유사도가 높은 판례를 제안하여 질의문에 해당하는 판례를 자동으로 연결하였다.