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The proton nuclear magnetic resonance spectral analysis of human blood plasma lipoprotein (혈장지 단백질에 대한 핵자기 공명 분광 분석)

  • Song, In-Chan;Kang, Sa-Ouk;Kim, Noe-Kyeong;Im, Jung-Gi;Min, Byoung-Goo
    • Proceedings of the KOSOMBE Conference
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    • v.1989 no.05
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    • pp.29-34
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    • 1989
  • 300 MHz proton NMR spectra of human blood plasma were analyzed by deconvolution of spectrum, and we compared its results with Fossel's test in normal (15 cases), liver cancer (14 cases) , and other cancer (14 cases) groups. This analysis had enabled us to obtain dynamic characteristics of each individual lipoprotein. As a result of deconvolution method, the VLDL and chylomicron intensity level were found to be elevated in the patients with liver cancer. Moment ratio values of $CH_2$ resonance in the raw spectrum were found to be higher than the normal group for patients with, malignant tumors other than liver cancer. These differences between the three groups could not be found in the conventional Fossel's test. We could simulate plasma spectra by addition of spectra of individual lipoproteins through deconvolution method. Further clinical trials in larger populations and additional biochemical method may shed new light on many of clinical and biochemical interests for knowing characteristics about lipoprotein not separated from blood and the background of Fossel test.

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Successful Treatment of Five Cases of Idiopathic Central Nervous System Hypersomnia (치료(治療)에 반응(反應)한 특발성(特發性) 중추성(中樞性) 수면과다증(睡眠過多症) 5예(例) 분석(分析))

  • Yoon, In-Young;Jeong, Do-Un
    • Sleep Medicine and Psychophysiology
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    • v.4 no.1
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    • pp.89-95
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    • 1997
  • The authors studied 5 cases of idiopathic CNS hypersomnia who visited Division of Sleep Studies, Seoul National University Hospital in 1995. Detailed medical history was taken and nocturnal polysomnography(NPSG), multiple sleep latency test(MSLT) and human leukocyte antigen(HLA) typing were performed. Neither cataplexy nor hypnagogic hallucination was reported in all cases and in NPSGs, there were tendencies of increased sleep period time and decreased slow wave sleep time. In MSLT, all the subjects showed average sleep latencies less than 8 minutes without sleep-onset rapid eye movement period(SOREMP). In HLA typing, some correlation between idiopathic CNS hypersomnia and HLA DR4 was observed. In contrast to previous reports, overall treatment response with methylphenidate was remarkable. Therefore, the authors suggest that patients suspected of idiopathic CNS hypersomnia be actively evaluated and treated with rather optimistic perspective.

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ORAL SQUAMOUS CELL CARCINOMA ASSOCIATED WITH HUMAN PAPILLOMAVIRUS INFECTIONS; TWO CASES REPORT AND REVIEW OF THE LITERATURE (인간유두종바이러스 감염과 연관된 구강내 편평상피세포암; 문헌고찰 및 증례보고)

  • Byun, June-Ho;Park, Bong-Wook;Lee, Jeong-Hee;Rho, Gyu-Jin;Kim, Jong-Ryoul
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.5
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    • pp.548-553
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    • 2007
  • Several investigators have shown that human papillomavirus(HPV) appear to play an etiologic role in oral and paranasal sinus carcinoma. It was known that 15-25% of head and neck squamous cell carcinoma(SCC) showed HPV-positive infection. Among them, HPV 16 was the most common type but HPV 18 was observed only 2-4% of HPV-positive head and neck cancers. In recent, we treated uncommon 2 oral SCC cases that associated with HPV infection. One is a case of tongue SCC after bone marrow transplantation(BMT), and the other is a case of SCC occurring with aspergillosis in the maxillary sinus. After surgery, HPV 16 and 18 were detected in the surgical specimens by the histological and polymerase chain reaction(PCR) examination. In this report, we present these cases with a review of literature.

Studies on the Isolation of Vibrio damsela (Vibrio damsela의 분리연구)

  • Ju, Jin-Woo;Kim, Il
    • The Journal of the Korean Society for Microbiology
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    • v.22 no.3
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    • pp.225-232
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    • 1987
  • Authors studied on the isolation of V. damsela from sea water, fish and shellfish at the Keoje Hae keumkang on the southern sea and at Hongdo island and Heucksan island on the western sea of Korea from May to September in 1986. Authors investigated for the isolated strains to bacteriological identification, hemolysis about various erythrocytes and antibiotic susceptibilities. The results obtained were as follows: 1. V. damsela was isolated 14 strains from total 383 specimens; 233 cases of sea water, 40 cases of fish and 110 cases of shellfish, respectively. Eight strains were isolated from sea water and 6 strains were isolated from shellfish. 2. The biochemical characteristics which differentiate it from other Vibrio species were indole negative, ornithine negative, Voges-Proskauer positive, arginine positive, galactose positive, glucose positive, maltose positive, mannose positive, trehalose positive, and growth in nutrient broth with 1% to 6% NaCl. 3. On hemolysis reaction on blood agar media using human, rabbit and guinea pig erythrocytes, human erythrocytes were 11 strain positive, rabbit erythrocytes were 12 strain positive and guinea pig erythrocytes were 13 strain positive. 4. Senistivity test using with chemotherapeutic agents of "BioLab" Microbial Sensitivity Test Discs were generally sensitived to amikacin, ampicillin, cephalothin, chloramphenicol, clindamycin, erythromycin, gentamycin, kanamycin, methicillin, penicillin, streptomycin, tetracycline and tobramycin, respectively, but were resistant to lincomycin.

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The Chromosome Studies in the Korean Population ( A Preliminary Note) (한국인의 염색체에 관한 연구(예보))

  • 김영선
    • The Korean Journal of Zoology
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    • v.7 no.1
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    • pp.29-32
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    • 1964
  • A study on chromosome of leucocytes in blood cultures derived from 6 normal Korean was performed . Exact chromosome counts were carried out on 205 cells in male, 211 in female , of which 86.05% revealed a chormosome mordal number of 46. On the basis of relative chromosome lengths and position of centromeres, the Karyotype that the human chromosomes were classified into 7 groups with 22 airs of autosome and one pair of sex chromosome was determined accoridng to the method of denver report. The chromosome number on metaphase was observed in short term cultures of leucocytes from the peripheral blood of 2 patients with chronic granulocytic leukemia and 1 patient with acute granulocitic leukemia . and the chromosome morpholoogy was also investigated in one acute leukemic patient. In all leukemic cases the leucocytes showed the constant value of 46 in the stem -line of chormosome number. But the frequency of cells with 46 chromosomes appeared in the 3 cases was 67.30% in average with a slightly higher range in hypo-andhyper-diploid chromosome numbers than in normal human, The idiogram analysis did not show any abnormality of chromosome in acute leukemic cells.

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Guidelines for Happiness : Lessons from the Cases in the 'Happy Family Story Contest' (행복감을 주는 삶의 지침 연구 -우리가정 행복나누기 공모사례분석을 통하여)

  • Lee Young-Ho;Chi Young-Sook;Choi Bo-A
    • Journal of Families and Better Life
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    • v.23 no.1 s.73
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    • pp.41-51
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    • 2005
  • At this time when the Healthy Family Act has become effective, promoting popular consciousness on a happy family life and providing guidelines to happiness are important. This study analyzed the content of 250 cases that entered the 'Happy Family Story Contest' in order to extract some common qualifies of happy families. As a result, nine characteristics were found: 1) a sense of achievement in having made a happy family 2) a sense of togetherness and solidarity 3) self-discipline 4) a Positive relationship with others 5) accomplishing one small step at one time 6) autonomy and candid communication 7) overcoming crises 8) cherishing what one has in the present 9) restraining greed and letting go. The findings of this study will help individuals reorient their lives as well as inspire the professionals to develop programs.

Spinal Deformity Detection Based on the Evaluation of Middle Line´s Displacement on a Moire Image of a Human Back

  • Kim, Hyoungseop;Seiji Ishikawa;Yoshinori Otsuka;Hisashi Shimizu;Takashi Shinomiya
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.105.1-105
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    • 2001
  • In this paper, a technique is described for classifying normal cases and abnormal cases in automatic spinal deformity detection by computer based on moire topographic images of human backs. Displacement is evaluated statistically between the middle line extracted from the entire moire image and the middle line obtained from a small rectangle area defined on the moire image. The middle line is calculated employing a developed potential symmetry analysis technique. The displacement is calculated in several regions and the mean and the standard deviation of the displacement values are chosen as two features. A linear discriminant function (LDF) is defined on the 2-D feature space based on the Mahalanobis distance and the features are classified into two categories, i.e., normal and ...

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Four Additional Cases of Diphyllobothrium nihonkaiense Infection Confirmed by Analysis of COX1 Gene in Korea

  • Park, Sang Hyun;Jeon, Hyeong Kyu;Kim, Jin Bong
    • Parasites, Hosts and Diseases
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    • v.53 no.1
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    • pp.105-108
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    • 2015
  • Most of the diphyllobothriid tapeworms isolated from human samples in the Republic of Korea (=Korea) have been identified as Diphyllobothrium nihonkaiense by genetic analysis. This paper reports confirmation of D. nihonkaiense infections in 4 additional human samples obtained between 1995 and 2014, which were analyzed at the Department of Parasitology, Hallym University College of Medicine, Korea. Analysis of the mitochondrial cytochrome c oxidase 1 (cox1) gene revealed a 98.5-99.5% similarity with a reference D. nihonkaiense sequence in GenBank. The present report adds 4 cases of D. nihonkaiense infections to the literature, indicating that the dominant diphyllobothriid tapeworm species in Korea is D. nihonkaiense but not D. latum.

Wives' and Husbands' Conflict Coping Styles and Marital Adaptation (부부의 갈등대처방법이 부인의 결혼생활적응에 미치는 영향)

  • Yi, Yeong-Sug;Park, Kyung-Rhan
    • Korean Journal of Human Ecology
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    • v.15 no.3
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    • pp.363-372
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    • 2006
  • The purpose of this study is to examine the influence of couples' conflict coping styles upon wives' marital adaptation. The results are as follows: First, the most often-used conflict coping style was 'compromise', and the least-used was 'smoothing over', in both cases of husbands and wives. Second, significant differences were found in 'compromise', 'integration', and 'smoothing over' between the cases of husbands and wives. For example, wives used 'compromise' and 'integration' more frequently than husbands, but 'smoothing over' was more often used by husbands. Third, the most important variable that influenced wives' stress and marital satisfaction was husbands' conflict coping styles. Their own conflict coping styles and demographic variables came as the next. Fourth, the only conflict coping style of wives that influenced the stress and the marital satisfaction was 'dominance'. On husbands' side, 'compromise (stress and marital satisfaction)' and 'dominance (marital satisfaction)' functioned as important variables.

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Fascioliasis in Korea : a review (한국산(韓國産) 간질(肝蛭)에 관한 연구(硏究)-문헌조사(文獻調査))

  • Lee, Chung-gil
    • Korean Journal of Veterinary Research
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    • v.33 no.3
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    • pp.555-565
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    • 1993
  • The studies on the liver fluke of Korea have been reviewed. The fluke is Fasciola hepatica. Its intermediate host is Lymnaea biridis, whose principal habitats are rice paddies. The first fascioliasis of Korean native(beef) cattle was reported in 1915. Bovine fascioliasis is present throughout the conuntry, including north Korea, with the average prevalence of 30%. The prevalence of the disease is about the same in dairy cattle, which have been imported from other countries since 1960s. The disease was also found in Korea in other species of animals such as sheep, goats, deer of zoo and farms, and guinea pigs of a laboratory. Human fascioliasis was reported ; 35 cases by fecal examination and 11 by both parasitology and pathology. Of the latter 11 cases, 5 were ectopic parasitism. Economic loss due to the reduced carcass weight and milk production, and liver condemnation was great. Almost all flukicides developed in other countries are commercially available in Korea.

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