• Title/Summary/Keyword: history of medicine

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A Study of Classification in the Terms of "Biwiron(脾胃論)" (비위론(脾胃論)에 기재된 용어 분류체계에 관한 연구)

  • Chung, Du-Young;Lee, Byung-Wook;Eom, Dong-Myung;Kim, Eun-Ha
    • Journal of Korean Medical classics
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    • v.22 no.1
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    • pp.191-205
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    • 2009
  • Objective : Up to the present, theories of medical books is too difficult to understand thoroughly. However, these study methods have some problems in dealing with lots of meaning because the comprehension of theories are dependent upon one's memory. Especially, comparison distinct medical books are more difficult matter. So, we have attempted to solve a problem. Method : We have researched medical terms in the "Piweilun" according to below the procedure. (1) Making a terms list: We have selected constituent of sentence. And we have made term list on the basis of concept of term. (2) Making a synonym list: We have collected identical conception and made a synonym list. So, using an synonym tables of DB, it is possible to search for the non-standard terms of medical theory. (3) Making a classification system: Using UMLS(Unified Medical Language System), MeSH(Medical Subject Headings), IST(International Standard Terminology) ect., we have made a classification system of oriental medicine terms in the "Piwelun". Analysis of relation between terms. Result : In the "Piweilun", there are more than 1,790s concepts. Parts of those are belonged to UMLS-Semantic Type, the other parts of those are not belonged to UMLS-Semantic Type. And those include predicate more than UMLS-Semantic Relations.

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A Study on Bio Art in Modification and Hybrid of Vegetables (식물의 변형과 혼성을 이용한 바이오아트 연구)

  • Jeon, Hyesook
    • The Journal of Art Theory & Practice
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    • no.15
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    • pp.137-165
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    • 2013
  • The prefix 'bio' with the meaning of 'life,' has been used for biotechnology, biochemistry, bioengineering, biomedicine, bioethics, bio-information as well as 'bio art' since 1990s. Bio art is an art as life itself and a kind of new direction in contemporary art that manipulates the processes of life. Bio artists use the properties of life and materials as scientists in laboratory of biology, and change organisms within their own species, of invents life with new characteristics. Technologically and socio-culturally, bio art has been connected with bioengineering. This essay is on the bio art that use vegetables, and on the specified gaze of so-called 'Sci-Artists.' Not only the genetically modified vegetables like works of George Gessert, Ackroyd & Harvey, and Eduardo Kac, but also the works made from the critical viewpoint like those of Paul Vanouse, Natalie Jeremijenko, and Amy Youngs, have 'the molecular gaze'(Suzanne Anker and Dorothy Nelkin's concept) of the genetic age in their art works. As the art history have showed, artists' gazes have insights about social problems that surround us. Bioartists' gazes reveal their insights about social and ethical problems, possibly concealed by science itself. Those problems are about results from practical discoveries of the sequencing of the genome, genetic engineering, cloning and reproduction of human and animals, body transformation, and the commercialization of cell and genes etc. We can find the significance of bioart in the molecular gaze about those problems, and we can rethink the identity of human, the reception of social influences from bio-technology and medicine.

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Organized Hematoma in the Maxillary Sinus (상악동에 발생한 organized hematoma)

  • Kim, Jae-Jin
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.32 no.5
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    • pp.473-477
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    • 2010
  • Organized hematoma of the maxillary sinus is a rare, nonneoplastic benign lesion with locally destructive behavior that may mimic a malignancy. Clinically, symptoms do not usually occur while the lesion remains localized to the maxillary sinus. Because there is gradual enlargement of the lesion causing erosion and displacement of the adjacent bony structures, symptoms such as epistaxis, cheek swelling, nasal obstruc-tion, headache, and exophthalmos become manifest. Radiologically, unilateral cases are much more fre-quent than bilateral, and Waters' view shows complete opacity of the expanded maxillary sinus and some masses. CT scan shows a large heterogeneous enhancing mass causing considerable expansion of the max-illary sinus with bony erosion. On MR imaging, the mass usually has a variable signal intensity on T1- and T2- weighted images, ranging from low to high. After contrast administration, discrete areas of enhance-ment are present within the mass. Although the disease is essentially benign and nonneoplastic, differen-tial diagnosis from neoplastic disease including malignancy both clinically and radiologically has been always problematic. Accurate preoperative diagnosis of organized hematoma of the maxillary sinus is important to avoid unnecessary extensive surgery, because this condition is curative with a simple, conservative surgical approach and rarely recur. Organized hematoma of the maxillary sinus should be included in the differential diagnosis when patients have recurrent epistaxis, slow-growing mass of the cheek, nasal obstruction, and expansile mass in the maxillary sinus. A 33-year-old man was referred to the department of oral and maxillofacial surgery with a three-month history of slowly growing painful swelling of the left cheek. The mass of the maxillary sinus was resected by a Caldwell-Luc approach. Histopahtoly showed only a fibous encapsulated organized hematoma. To our knowledge, organized hematoma of the maxillary sinus has not been previously described in the Korean literature of the oral and maxillofacial surgery. We report a case of organized hematoma of the maxillary sinus presenting with an enlarging maxillary sinus mass.

Changes in Nutritional Status of General Medical Patients During Hospitalization (내과 환자의 입원후 영양상태 변화 연구)

  • 양영희;최스미;김은경
    • Journal of Korean Academy of Nursing
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    • v.27 no.1
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    • pp.49-60
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    • 1997
  • The purpose of this study was to determine the incidence of malnutrition among patients on admission to hospital, to monitor changes in their nutritional status during hospitalization, and to determine the factors which might affect changes in nutritional status. The subjects for the study were patients who were admitted to general medicine for more than one week. Patients suffering from cardiovascular. renal disease, or dehydration were excluded. Nutritional assessment of the patients was performed on admission and nutritional status was reassessed one week and two weeks after admission. The nutritional assessment tool consisted of subjective history taking and anthropometric measurements. Biochemical measurements were performed only on admission. For anthropometric assessment : patients' body weight, subcutaneous skinfolds thickness, % of body fat, body mass index, and lean body mass were measured using caliper or Bio impedance Analyzer. Factors which might influence current nutritional status, like dietary intake, anorexia, nausea, vomiting, diarrhea, sleep disturbance, and number of days of NPO for diagnostic examinations were analyzed. The results are as follows : 1. Of the 59 patients who were studied, 61% were male and 39% female. The nutritional status of all of the 59 subjects was reassessed one week after admission, but it was only done for 22 subjects at two weeks. 2. The anthropometric measurements. including weight body mass index, lean body mass, body fat. and skin fold thickness. were all significantly decreased at one week after admission compared to the values at admission. On the other hand, two weeks after admission, only body weight and abdominal skinfolds thickness were decreased. 3. The subjects reported anorexia for an average of two days, sleep disturbance for two days, and no food intake due to diagnostic test for one day. In the second week of hospitalization, almost none of the patients complained of gastrointestinal symptoms or sleep disturbance except anorexia. Food consumption which was measured based on rice intake was 60% of the food served during the first week of hospitalization, and 66% during the second week of hospitalization. 4. There was no correlation between the subjective nutritional assessment and anthropometric assessment. 5. There was no statistical significance in anthropometric measurements among the patients with various diseases whereas sleep disturbance and no food intake due to various diagnostic test was prominent in patients with gastrointestinal diseases.

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Prescription Patterns and Factors Related to the Number of Medications in Chronic Obstructive Pulmonary Disease in Non-elderly Adults (비고령 성인환자의 만성폐쇄성폐질환 약물사용 현황과 영향인자)

  • Moon, Chae-won;Ra, Hyun-O;Rhie, Sandy Jeong
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.4
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    • pp.298-305
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    • 2016
  • Background: This study is to investigate the prescription patterns and factors related to the number of medications treating chronic obstructive pulmonary disease (COPD) in patients under 65 years old according to GOLD guidelines. Methods: We retrospectively analyzed the medical records of patients aged 40-64 years with a diagnosis of COPD from January to March 2016. Patients were classified by combined assessment of COPD (grades A, B, C, D) using spirometry, exacerbation history, mMRC, and/or CAT results. We analyzed prescribed medications, treatment options and factors related to the numbers of COPD medications. Results: The total number of prescriptions were 251. About 35.5% of patients were classified as GOLD A, 34.2% as GOLD B, 17.1% as GOLD C and 13.2% as GOLD D. Inhaled bronchodilator was prescribed for 86.9% of patients and the most frequent COPD medication was long-acting muscarinic antagonist (LAMA) followed by inhaled corticosteroids/long acting beta agonist (ICS/LABA). The majority of low risk patients (GOLD A/B) were prescribed a monotherapy with LAMA or LABA. For high risk patients (GOLD C/D), combination treatment with ICS+LAMA+LABA was mostly prescribed. The 21.2% of patients in GOLD D received systemic corticosteroid. The average number of medications per prescription was 3.7, and this number increased with increasing COPD grade, COPD duration and lung function reduction ($FEV_1$, $FEV_1/FVC$). Conclusion: Generally high adherence to GOLD guideline recommendations was reported. Given the progressive nature of the disease, results suggest that closer attention to respiratory symptoms for early detection, diagnosis, and appropriate treatment of COPD is warranted.

Study on the correlation between assignment of the Three Eums and Yangs to calendar in the "Somun.Make'ae" and the exterior interior relationships of the Meridian ("소문(素問).맥해(脈解)"의 삼음삼양(三陰三陽) 월(月) 배속(配屬)과 경락(輕絡) 표리(表裏)의 상관성에 대한 연구)

  • Bang Jung-Kyun
    • Korean Journal of Acupuncture
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    • v.23 no.4
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    • pp.59-65
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    • 2006
  • Objectives : By comparing the correspondence of Three Eums and Yangs (三陰三陽) to calendr in ${\ulcorner}Somun\;Make'ae{\lrcorner}$ with twelve principal divinatory symbols, this paper intends to explain the exterior and interior of meridian system using the phenomena of the trigrams from Juyeok(卦). It also tries to relate the phenomena of the trigrams with the characteristics of the original Gi (本氣) of Three Em and Yangs tough the interpretation of Three Eums and Yangs assigned to twelve principal divinatory symbols. Methods : This paper compares the correspondence of Three Eums and Yangs to calendar in ${\ulcorner}Somun\;Make'ae{\lrcorner}$ with twelve principal divinatory symbols. By this, it traces the making of the exterior and interior relationship between Taeeum (太陰)-Yangmyeong (陽明), Soeum (少陰)-Taeyang (太陽), and Gworeum (厥陰)-Soyang (少陽) through the phenomena of trigrams assigned to Three Eums and Yangs. It also interprets Three Em and Yangs assigned to twelve principal divinatory symbols, using the original Gi of the six atmospheric influences(六氣). Results and Conclusions : Three Eums and Yangs in ${\ulcorner}Somun\;Make'ae{\lrcorner}$ signify the six meridians of the leg. Soeum (少陰) is assigned to October in ${\ulcorner}Somun\;Make'ae{\lrcorner}$ but it is more appropriate to assign it to July. If Soeum (少陰) is assigned to July, Three Eums and Yangs have phenoma of the trigrams with Em and Yang lines (陽爻) counter to each other, and can be explained as the exterior and interior relationship. lastly, in case of Three Eums and Yangs assigned to twelve principal divinatory symbols, the phenomena of the trigrams can be interpreted as the original Gi of Three Eums and Yangs.

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Folate during reproduction: the Canadian experience with folic acid fortification

  • Lindzon, Gillian;O'Connor, Deborah L.
    • Nutrition Research and Practice
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    • v.1 no.3
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    • pp.163-174
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    • 2007
  • Folate has received international attention regarding its role in the risk-reduction of birth defects, specifically neural tube defects (NTDs). In 1998 health officials in Canada, like the United States, mandated the addition of folic acid to white flour and select grain product's to increase the folate intake of reproductive-aged women. Subsequent to this initiative there has been an increase in blood folate concentrations in Canada and a 50% reduction in NTDs. Many countries, including Korea, have not mandated folic acid fortification of their food supply. Reasons vary but often include concern over the masking of vitamin $B_{12}$ deficiency, a belief that folate intakes among womenare adequate, low priority relative to other domestic issues, and the philosophy that individuals have the right not to consume supplemental folic acid if they so choose. Prior to folic acid fortification of the food supply in Canada, the folate intakes of women were low, and their blood folate concentrations while not sufficiently low to produce overt signs of folate deficiency (eg. anemia) were inconsistent with a level known to reduce the risk of an NTD-affected pregnancy. The purpose of this article is to describe the role of folate during the periconceptional period, pregnancy, and during lactation. The rationale for, and history of recommending folic acid-containing supplements during the periconceptional period and pregnancy is described as is folic acid fortification of the food supply. The impact of folic acid fortification in Canada is discussed, and unresolved issues associated with this policy described. While the incidence of NTDs in Canada pre-folic acid fortification were seemingly higherthan that of Korea today, blood folate levels of Korean women are strikingly similar. We will briefly explore these parallels in an attempt to understand whether folic acid fortification of the food supply in Korean might be worth consideration.

Do Blebs or Bullae on High-Resolution Computed Tomography Predict Ipsilateral Recurrence in Young Patients at the First Episode of Primary Spontaneous Pneumothorax?

  • Park, Sungjoon;Jang, Hyo Jun;Song, Ju Hoon;Bae, So Young;Kim, Hyuck;Nam, Seung Hyuk;Lee, Jun Ho
    • Journal of Chest Surgery
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    • v.52 no.2
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    • pp.91-99
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    • 2019
  • Background: The relationship between the size of bullae and pneumothorax recurrence is controversial. The aim of this study was to retrospectively evaluate the role of blebs or bullae in predicting ipsilateral recurrence in young patients experiencing their first episode of primary spontaneous pneumothorax (PSP) who underwent conservative treatment. Methods: A total of 299 cases of first-episode PSP were analyzed. The status of blebs or bullae was reviewed on high-resolution computed tomography (HRCT). The dystrophic severity score (DSS; range, 0 to 6 points) was calculated based on HRCT. Results: The 5-year recurrence rate was 38.2%. In univariate analysis, age (<20 years), body mass index (<$20kg/m^2$), a unilateral lesion, and intermediate risk (DSS 4 and 5) were associated with recurrence. Sex; smoking history; and the presence, number, and maximal size of blebs or bullae were not related to recurrence. In Cox regression, age and intermediate risk were independent risk factors for recurrence. High risk (DDS 6) was not an independent risk factor. Conclusion: The presence, number, and size of blebs or bullae did not affect ipsilateral recurrence. DSS failed to show a positive correlation between severity and recurrence. The decision to perform surgery in patients experiencing their first episode of PSP should not be determined by the severity of blebs and bullae.

Clinical Characteristics of Disability in Patients with Indoor Aire-Related Environmental Intolerance

  • Vuokko, Aki;Karvala, Kirsi;Suojalehto, Hille;Lindholm, Harri;Selinheimo, Sanna;Heinonen-Guzejev, Marja;Leppamaki, Sami;Cederstrom, Sebastian;Hublin, Christer;Tuisku, Katinka;Sainio, Markku
    • Safety and Health at Work
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    • v.10 no.3
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    • pp.362-369
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    • 2019
  • Background: Chronic nonspecific symptoms attributed to indoor nonindustrial work environments are common and may cause disability, but the medical nature of this disability is unclear. The aim was to medically characterize the disability manifested by chronic, recurrent symptoms and restrictions to work participation attributed to low-level indoor pollutants at workplace and whether the condition shares features with idiopathic environmental intolerance. Methods: We investigated 12 patients with indoor aire-related work disability. The examinations included somatic, psychological, and psychiatric evaluations as well as investigations of the autonomic nervous system, cortisol measurements, lung function, and allergy tests. We evaluated well-being, health, disability, insomnia, pain, anxiety, depression, and burnout via questionnaires. Results: The mean symptom history was 10.5 years; for disabling symptoms, 2.7 years. Eleven patients reported reactions triggered mainly by indoor molds, one by fragrances only. Ten reported sensitivity to odorous chemicals, and three, electric devices. Nearly all had co-occurrent somatic and psychiatric diagnoses and signs of pain, insomnia, burnout, and/or elevated sympathetic responses. Avoiding certain environments had led to restrictions in several life areas. On self-assessment scales, disability showed higher severity and anxiety showed lower severity than in physician assessments. Conclusion: No medical cause was found to explain the disability. Findings support that the condition is a form of idiopathic environmental intolerance and belongs to functional somatic syndromes. Instead of endless avoidance, rehabilitation approaches of functional somatic syndromes are applicable.

Risk Factors of Clonorchis sinensis Human Infections in Endemic Areas, Haman-Gun, Republic of Korea: A Case-Control Study

  • Lee, Sang-Eun;Shin, Hee-Eun;Lee, Myoung-Ro;Kim, Yang-Hee;Cho, Shin-Hyeong;Ju, Jung-Won
    • Parasites, Hosts and Diseases
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    • v.58 no.6
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    • pp.647-652
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    • 2020
  • Clonorchis sinensis is the most common fish-borne intestinal parasite in Korea. The aim of the present investigation was to survey the status of C. sinensis infection and analyze associated risk factors in residents of Haman-gun, Gyeongsangnam-do. A total of 5,114 residents from 10 administrative towns/villages voluntarily agreed to participate in the study, which comprised fecal examination, a questionnaire survey for risk factors, ultrasonography, and enzyme-linked immunosorbent assay for cancer biomarker detection in the blood. We detected C. sinensis eggs in 5.3% of the subjects. By region, Gunbuk-myeon had the highest number of residents with C. sinensis eggs. The infection rate and intensity were higher in male than in female residents. Based on the risk factor questionnaire, infection was highly associated with drinking, a history of C. sinensis infection, and the practice of eating of raw freshwater fish. Extension of the bile duct, infection intensity, and cancer biomarker detection significantly correlated with the presence of eggs in the study population. In conclusion, the development of feasible, long-term control policies and strategies for the elimination of C. sinensis in Korea is still required.