• Journal of Korean Medical classics
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• v.31 no.4
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• pp.17-26
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• 2018

Objectives : This paper studies Zhushang, which is the name of a disease found in excavated books. Zhusang is the first disease listed in Wushierbingfang, which is a medical textbook excavated at Mawangdui, and Zhusang was followed by diseases such as Jinshang and Renshang. The paper studies what disease each of the word is refering to in terms of graphonomy, and compared the difference of their treatment from other classical texts. Methods : The scope of the study of this paper includes the excavated textbooks that seem to contain any disease related to Zhusang, and the two major text books of these are Wushierbingfang and Wuweihandaiyijian. Then Shennongbencao jing, which is the one of the earlier books on herbology, and Bencao gangmu, which was written based on the former, wer used to make comparisons. Parts in Donguibogam that seem to be related to the parts in the excavated texts were also compared. The study was done by first performing historical research on the names of the diseases in the excavated books, and compared them with the contents of the classical texts. Results : The Zhushang discovered in Wushierbingfang refers to wounds caused by metal or wood. It was interesting how they created a word for diseases depending on the cause. Only Jinshang is found in Wuweihandaiyijian, and the fact that different causes gave way to different names tells us that they had corresponding treatment. The categorization of Zhushang, Jinshang, and Renshang is corresponded better in Donguibogam than Chinese medical books.

• Journal of Conservation Science
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• v.29 no.1
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• pp.15-24
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• 2013

Chil-sa head-wear excavated in Buksandong of Ulsan is precious relic with historical, cultural, social and artistic values because it shows head-wear shape at the period of Goryeo dynasty with the invaluable worth in the field of Korean traditional costumes. Also, this excavated head-wear provides the empirical information about Goryeo dynasty which has relatively insufficient remains. The purposes of this study are to recover and maintain the original states of the artifacts from various environmental factors and then to preserve the materials from rapid decomposition. As a result, the original shape of the head-wear from Goryeo dynasty can be conserved and through the material and structure analysis it is found out that the head-wear's surface structure is composed of silk(紗) and the ground structure is made by bamboo(竹絲).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.3
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• pp.1-7
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• 2004

Objectives: In order to establish a base for proper treatment and management of patients with dermal problems through correct diagnosis, I considered the naming rule for dermatology in Oriental Medicine, referring to the dermatology literature compared to western medicine. In addition, this paper examines the characteristic classification of dermatology. Methods: I examined the naming rule of dermatology in Oriental Medicine and then compared the disease names in Oriental and Western medicine and the characteristic classification of dermatology referred to the records. Results: The dermal diseases have been named according to their colors and morphologies, causes, progress of symptoms, recurrent sites, the character of distribution, recurrent seasons, ages, the character of patients' jobs and locations. Sometimes some have been named by referring to their main morphologies, sites, causes, colors and seasons synthetically. However it was found some names for dermal diseases, even though the same diseases, had been named differently according to for example: historical times, condition of locations and the quality of doctors whose process of naming developed and changed over time. The relationship between Oriental and Western medicine of each name for dermal diseases is basically divided into 5 types: same names - same diseases; same names but different diseases; same diseases but different names; one disease with multiple names; and one name with multiple diseases. Considering the methods of classification, these were generally achieved according to their places of origin. It is a method unique to Oriental medicine that we classified some dermal diseases into 疥, 癬, 瘡, 風, 丹, 疱, 疹, 癰, 痘, 疽 and so on and it is very easy to diagnose which part they belong to. This was classified by putting first the causes of diseases; for instance: viruses, bacteria, fungi. Sometimes, however there was a problem, connected to the classification of morphology. Conclusions: I suggest that we need to unify and refine dermatological terms in Oriental Medicine in order to establish a base for proper treatment and management of patients with dermal problems through correct diagnoses.

• Communications for Statistical Applications and Methods
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• v.24 no.6
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• pp.561-581
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• 2017

Bayesian statistics can play a key role in the design and analysis of clinical trials and this has been demonstrated for medical device trials. By 1995 Bayesian statistics had been well developed and the revolution in computing powers and Markov chain Monte Carlo development made calculation of posterior distributions within computational reach. The Food and Drug Administration (FDA) initiative of Bayesian statistics in medical device clinical trials, which began almost 20 years ago, is reviewed in detail along with some of the key decisions that were made along the way. Both Bayesian hierarchical modeling using data from previous studies and Bayesian adaptive designs, usually with a non-informative prior, are discussed. The leveraging of prior study data has been accomplished through Bayesian hierarchical modeling. An enormous advantage of Bayesian adaptive designs is achieved when it is accompanied by modeling of the primary endpoint to produce the predictive posterior distribution. Simulations are crucial to providing the operating characteristics of the Bayesian design, especially for a complex adaptive design. The 2010 FDA Bayesian guidance for medical device trials addressed both approaches as well as exchangeability, Type I error, and sample size. Treatment response adaptive randomization using the famous extracorporeal membrane oxygenation example is discussed. An interesting real example of a Bayesian analysis using a failed trial with an interesting subgroup as prior information is presented. The implications of the likelihood principle are considered. A recent exciting area using Bayesian hierarchical modeling has been the pediatric extrapolation using adult data in clinical trials. Historical control information from previous trials is an underused area that lends itself easily to Bayesian methods. The future including recent trends, decision theoretic trials, Bayesian benefit-risk, virtual patients, and the appalling lack of penetration of Bayesian clinical trials in the medical literature are discussed.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.20 no.1
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• pp.15-26
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• 2016

Objectives Syndrome differentiation and treatment (辨證論治) was one of the core theories in Korean medicine and syndrome differentiation (辨證) constitutes a branch of disease diagnosis in Korean medicine. Yoon Gil-Young, one of the modern outstanding scholar of basic medical science in Korean medicine, wrote on basic theories of Korean medicine such as physiology, pathology, formula science, etc. Hereby we will analyze and discuss his works to understand his recognition of historical changes in the syndrome differentiation. Methods We conducted researches into the two works of Yoon Gil-Young's, which are "The Clinical Formula Science of Eastern Medicine (東醫臨床方劑學)" and "The theory of Four-Constitution Medicine (四象體質醫學論)". From Yoon's academic standpoint which connects the basic medical science with the clinical medicine, we analyzed his opinion about the system in the Theory of 'Syndrome Differentiation'. Results According to Yoon's research work on the Theory of 'Syndrome Differentiation', the system of syndrome differentiation, which had its deep root in the theory of Yin and Yang (陰陽) & the theory of abbreviation of the five circuit phases (五運) and the six atomspheric influences (六氣) of the "Huangdi's Internal Classic (黃帝內經)". Conclusions Yoon Gil-Young's theory of differentiation of syndromes and treatment is widespread so much that he studied on the learning field of Traditional Korean Mediciine and ingenious as well. He explain on the main principles of differentiation of syndromes based on "Huang Di Nei Jing" and the system of differentiation of syndromes is composed of Traditional Korean Medical Physiology.

• Korean Journal of Biological Psychiatry
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• v.21 no.4
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• pp.118-127
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• 2014

Along with language, socialization is a unique feature of the human being. There is a continuous debate regarding whether the development of socialization is innate, and conducted by the environment in the growing process, or the result of the interaction of both aspects. If socialization is the result of the interaction with the environment or is an acquired developmental process, the following question rises. "Is there a 'critical period' for the development of socialization?" Although there are a huge number of studies seeking for treatment and solutions for developmental delay or deficits of socialization, it is very complicated question to answer. Historical figures such as 'Hugh Blair' of Borgue in England, and 'the wild boy of Aveyron' in France, seem to have innate socialization deficits. Nowadays patients with non-verbal learning disorder, social communication disorder, or autism spectrum disorder seem to have genetic defects. On the other hand, Harry Harlow's monkey experiments, hikikomori of Japan, Romanian orphans and patients with reactive attachment disorder seem to display social deficits due to environmental factors. However, it is not easy to clearly draw a line between innate or acquired factors. Therefore, rather than subdividing the diseases for etiological and pathophysiological approach to heterogenous groups with the common denominator of social deficit, and for the research of pathophysiology and treatment development, the authors suggest a comprehensive concept of "social dysfunction spectrum."

• Solar Energy
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• v.15 no.1
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• pp.13-28
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• 1995

In this study, the history of Korean traditional Ondol was investigated and the latent heat materials and bioceramics were selected to develop the latent heat storage-bioceramics Ondol system based on the Korean traditional Ondol(sensible heat storage type), and the thermal characteristics of Ondol were analyzed experimentally The results could be summarized as follows; 1. Korean traditional Ondol has been originated in "Whaduk" which had been utilized continuously for about $2{\times}10^6$ years from the Old Stone Age to the Bronze Age, and Korean traditional Ondol using in these days has been utilized for about 976 years from the Koryu Dynasty to the Modern Ages. 2. $Na_2SO_4{\cdot}10H_2O(SSD)$ was selected as latent heat material for the latent heat storage Ondol. 3. Ondol unit was filled with the latent heat material of 0.63 kg and the dimension of Ondol unit was $400mm{\times}400mm{\times}27mm(width{\t\imes}depth{\times}height)$. 4. The comfortable surface temperature($23{\sim}29^{\circ}C$) of the latent heat storage Ondol was lasted 5 hours at the room temperature of $16{\sim}18^{\circ}C$, whereas that of sensible heat storage Ondol was lasted only 1.0 hours in the same conditions. 5. For the thermal effect of bioceramics, the Ondol air temperature i.n case of bioceramics treatment on the pannel was higher than that of without bioceramics treatment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.1222-1227
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• 2014

Recording materials are the valuable historical and cultural parts themselves as well as the methods for exchanging informations. Therefore, the appropriate conservation treatments should be conducted to the recording materials respectively. In case of the paper records, some particular conservation treatments such as a deacidification and a sterilization are necessary to prevent both bio and chemical deteriorations. In this research, the nano-scaled ZnO and MgO with 10~30nm size were prepared for the effective and stable conservation treatment of the paper records. Deacidification and sterilization effect of nano compounds were excellent and since nano compounds had almost 100% purity(free from Pb, Cd, As), the additional damages caused by the heavy and toxic metals should not be occur to the books and papers.

• International Journal of Advanced Culture Technology
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• v.8 no.4
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• pp.167-176
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• 2020

Recommendation Systems is the top requirements for many people and researchers for the need required by them with the proper suggestion with their personal indeed, sorting and suggesting doctor to the patient. Most of the rating prediction in recommendation systems are based on patient's feedback with their information regarding their treatment. Patient's preferences will be based on the historical behaviour of similar patients. The similarity between the patients is generally measured by the patient's feedback with the information about the doctor with the treatment methods with their success rate. This paper presents a new method of predicting Top Ranked Doctor's in recommendation systems. The proposed Recommendation system starts by identifying the similar doctor based on the patients' health requirements and cluster them using K-Means Efficient Clustering. Our proposed K-Means Clustering with Content Based Doctor Recommendation for Cancer (KMC-CBD) helps users to find an optimal solution. The core component of KMC-CBD Recommended system suggests patients with top recommended doctors similar to the other patients who already treated with that doctor and supports the choice of the doctor and the hospital for the patient requirements and their health condition. The recommendation System first computes K-Means Clustering is an unsupervised learning among Doctors according to their profile and list the Doctors according to their Medical profile. Then the Content based doctor recommendation System generates a Top rated list of doctors for the given patient profile by exploiting health data shared by the crowd internet community. Patients can find the most similar patients, so that they can analyze how they are treated for the similar diseases, and they can send and receive suggestions to solve their health issues. In order to the improve Recommendation system efficiency, the patient can express their health information by a natural-language sentence. The Recommendation system analyze and identifies the most relevant medical area for that specific case and uses this information for the recommendation task. Provided by users as well as the recommended system to suggest the right doctors for a specific health problem. Our proposed system is implemented in Python with necessary functions and dataset.

• Journal of Preventive Medicine and Public Health
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• v.55 no.4
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• pp.351-359
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• 2022

Objectives: The Regional CardioCerebroVascular Center (RCCVC) project was initiated to improve clinical outcomes for patients with acute myocardial infarction or stroke in non-capital areas of Korea. The purpose of this study was to evaluate the outcomes and issues identified by the Busan RCCVC project in the treatment of ST-segment elevation myocardial infarction (STEMI). Methods: Among the patients who were registered in the Korean Registry of Acute Myocardial Infarction for the RCCVC project between 2007 and 2019, those who underwent percutaneous coronary intervention (PCI) for STEMI at the Busan RCCVC were selected, and their medical data were compared with a historical cohort. Results: In total, 1161 patients were selected for the analysis. Ten years after the implementation of the Busan RCCVC project, the median door-to-balloon time was reduced from 86 (interquartile range [IQR], 64-116) to 54 (IQR, 44-61) minutes, and the median symptom-to-balloon time was reduced from 256 (IQR, 180-407) to 189 (IQR, 118-305) minutes (p<0.001). Inversely, the false-positive PCI team activation rate increased from 0.6% to 21.4% (p<0.001). However, the 1-year cardiovascular death and major adverse cardiac event rates did not change. Even after 10 years, approximately 75% of the patients had a symptom-to-balloon time over 120 minutes, and approximately 50% of the patients underwent inter-hospital transfer for primary PCI. Conclusions: A decade after the implementation of the Busan RCCVC project, although time parameters for early reperfusion therapy for STEMI improved, at the cost of an increased false-positive PCI team activation rate, survival outcomes were unchanged.