• Title/Summary/Keyword: higher-pair

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The Effects of Small Group Drawing in Learning the Particulate Nature of Matter (물질의 입자성에 대한 학습에서 소집단 그림 그리기의 효과)

  • Han, Jae-Young;Kim, Hun-Sik;Kim, Bo-Kyung;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.25 no.7
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    • pp.721-727
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    • 2005
  • This study investigated the effects of small group drawing in learning the concepts of particulate nature of matter. Three classes of seventh graders (N = 126) at a coed middle school were randomly assigned to a pair drawing group, an individualistic drawing group, and a control group. The students were taught the 'three states of matter' and 'motion of molecules' for eight class periods. Prior to these classes, student self-efficacy, learning motivation, and attitude toward science instruction were examined. After instruction, tests assessing achievement, conception, learning motivation, and attitude toward science instruction were administered. Two-way ANCOVA results revealed that scores of achievement and conception for the pair drawing group were significantly higher than those for the control group. However, scores of the three groups did not significantly differ in learning motivation and attitude toward science instruction. Furthermore, no significant interactions surfaced between instruction and the level of self-efficacy in all dependent variables.

Ab Initio Studies on Proton Affinities of Substituted Thiazoles (치환 티아졸의 양성자 친화도에 대한 Ab Initio 연구)

  • Lee, Gap Yong;Lee, Hyun Mee
    • Journal of the Korean Chemical Society
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    • v.42 no.1
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    • pp.1-8
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    • 1998
  • Molecular electrostatic potential (MEP) of the thiazole, relevant to the binding of lexitroposin that contains thiazole ring to the base pair of minor groove of DNA is obtained from the results of ab initio calculation. The geometry optimization for the two possible conformations of protonated thiazoles is performed with the aid of MNDO and ab initio calculations. The proton affinities are calculated at the 6-31G and 6-31G basis set for the optimized geometry. The proton affinities are also studied for various substituted thiazoles with the electron-donating and electron-withdrawing groups to estimate substituent effect on the proton affinity of thiazoles. It is found that the thiazole with nitrogen atom aligned inward to the DNA minor groove exhibit higher proton affinity and electron-donating substituents increase the proton affinity of thiazoles.ĀȀꃏ?⨀缾ĀȀ會ĀȀ?⨀ꖓĀĀȀ會ĀȀ僐?⨀聥ꖓĀĀȀ會ĀȀ꣐?⨀聐缾ĀȀ會ĀȀÑ?⨀ၑ缾ĀȀ會ĀȀ壑?⨀ꁑ缾ᨀĀꀏ會Āꀏ냑?⨀⡒缾᐀Āꀏ會Āꀏ࣒?⨀끒缾ᰀĀꀏ會Āꀏ惒?⨀ꁩꖓȀĀꀏ會Āꀏ룒?⨀⡪ꖓሀĀꀏ會Āꀏდ?⨀ᤐ돀삺?⨀塨?⨀飣?⨀돐룣?⨀偠잖⨀샣?⨀줏덐탣?⨀젏ꠏܞȌ蠀ᥲ⴯ͧMolecua及컲ࡔȏᰗۊऀںMolecular electrostatic potential (MEP) of the thiazole, relevant to the binding of lexitroposin that contains thiazole ring to the base pair of minor groove of DNA is obtained from the results of ab initio calculation. The geometry optimization for the two possible conformations of protonated thiazoles

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Current perception threshold in diabetic sensory polyneuropathy with normal routine nerve conduction study

  • Park, Kyung Seok;Kwon, Yong Chul;Youn, Minjung;Park, Yong-Shik;Hong, Yoon-Ho;Sung, Jung-Joon
    • Annals of Clinical Neurophysiology
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    • v.19 no.2
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    • pp.125-130
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    • 2017
  • Background: Routine nerve conduction study (NCS) can only be used to evaluate the function of large fibers, and the results of NCS are often normal in patients with distal sensory polyneuropathy. The measurement of the current perception threshold (CPT) has been reported to represent a variety of peripheral nerve fiber functions. This study was performed to investigate the value of measuring CPT in patients with diabetic sensory polyneuropathy who have no abnormalities in routine NCS. Methods: Twenty-seven diabetic patients with sensory polyneuropathy and normal routine NCS and 18 age-matched control subjects participated in this study. The CPT was measured on the unilateral index finger and great toe of each subject at frequencies of 5 Hz, 250 Hz, and 2,000 Hz. Results: CPT values were significantly higher in the patient group than in the control group, especially with stimuli at the lowest frequency of 5 Hz (p < 0.05). There were significant correlations between the CPT values obtained at three different frequencies in the patient group, whereas the correlation was only significant in the pair of 250 Hz/5 Hz (both in the hands and feet), and in the pair of 2,000 Hz/250 Hz (in the feet) for the control group. Conclusions: Our data suggest that the CPT test, especially at a stimuli frequency of 5 Hz, may be a useful screening tool for diabetic polyneuropathy in patients who show no abnormalities in routine NCS.

Peak-to-Average Power Ratio of Orthogonal Frequency Division Multiplexing with ICI Self-Cancellation (채널간간섭 자기소거법이 적용된 직교 주파수분할다중화의 첨두전력 대 평균전력비)

  • Kang Seog Gen
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.42 no.1
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    • pp.1-8
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    • 2005
  • In this paper, peak-to-average power ratio (PAPR) of orthogonal frequency division multiplexing (OFDM) with respect to the subchannel coding schemes for interchannel interference (ICI) self-cancellation is analyzed. It is shown theoretically and experimentally that a shaping component is generated in the transmitted sequence in the conventional correlative coding where a pair of antipodal signals is assigned in adjacent subchannels. Due to the shaping component, the signal powers in the mid and edges of a symbol are scaled by different weighting coefficients, resulting in increased PAPR. To overcome this problem a simple adjacent subchannel coding scheme is presented in this paper. In the new scheme, the shaping component caused by partial repetition of signals is eliminated by assigning a pair of signals in which phase difference varies signal-to-signal. As results, the new scheme has 2-3 dB smaller PAPR than the conventional ICI self-cancellation OFDM while maintaining much higher carrier-to-interference ratio than a normal OFDM system.

Korean Dress Collection Held in the Museum of Archaeology and Anthropology in Cambridge (캠브리지 대학 고고인류학 박물관 소장 한복유물에 관한 연구)

  • Kim, Soon-Young
    • Journal of the Korean Society of Costume
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    • v.61 no.9
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    • pp.84-96
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    • 2011
  • This paper investigates the formative features and the historical meaning of the Korean dress collection held in the Museum of Archaeology and Anthropology in Cambridge. The Museum holds a total of eleven items of koran dresses that were donated by two anthropologists in the first half of the twentieth century. Male dresses consist of a white cotton jacket (Jeogori), a under-vest (Deungbaeja) made of light wisteria rings, a headband (Manggeon) made of horsehair, a broad brimmed top hat (Gat) made of black horsehair gauze, an oilskin cover (Galmo) drawn over the hat in wet weather, and a hemispherical hat box (Gatjib). Female dresses comprise a pink silk jacket (Jeogori), a blue silk skirt (Chima) with pleats, a pair of woman's white cotton trousers (Sokgot), a black silk cap (Jobawi) decorated with pink tassels and imitation pearls, and a pair of green and magenta silk shoes (Danghye) with leather soles and metal rivets. Theses Korean dresses show what the western anthropologists had interests in. When collectors collect the folk objects, they thought much of the specificity of shape and material, the esthetic appreciation, and the representation of daily life. In terms of the value as the historical materials in the history of Korean dress, the under-vest of wisteria, the hat box, and the female dresses are worth paying attention to. The under-vest is one that was produced in earlier time among the remaining under-vests. The hat box represents that the hat belonged to the merchant classes. The female dress items show daily dresses worn by women of higher classes of the society in the 1920s.

Study on Modeling and Experiment of Optical Three Axis Tool-Origin Sensor for Applications of Micro Machine-Tools (초소형 공작기계 적용을 고려한 광학식 3 축 공구원점 센서 모델링 및 실험에 관한 연구)

  • Shin, Woo-Cheol;Lee, Hyeon-Hwa;Ro, Seung-Kook;Park, Jong-Kweon;Noh, Myoung-Gyu
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.6
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    • pp.68-73
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    • 2009
  • One of the traditional optical methods to monitor a tool is a CCD sensor-based vision system which captures an aspect of the tool in real time. In the case using the CCD sensor, specific lens-modules are necessary to monitor the tool with higher resolution than its pixel size, and a microprocessor is required to attain desired data from captured images. Thus theses additional devices make the entire measurement system complex. Another method is to use a pair of an optical source and a detector per measuring axis. Since the method is based on the intensity modulation, the structure of the measurement system is simper than the CCD sensor-based vision system. However, in the case measuring the three dimensional position of the tool, it is difficult to apply to micro machine-tools because there may not be space to integrate three pairs of an optical source and a detector. In this paper, in order to develop a tool-origin measurement system which is employed in micro machine-tools, the improved method to measure a tool origin in x, y and z axes is introduced. The method is based on the intensity modulation and employs one pair of an optical source radiating divergent beams and a quadrant photodiode to detect a three dimensional position of the tool. This paper presents the measurement models of the proposed tool-origin sensor. The models were verified experimentally The verification results show that the proposed method is possible and the induced models are available for design.

Effect of Ion Pair on Thermostability of F1 Protease: Integration of Computational and Experimental Approaches

  • Rahman, Raja Noor Zaliha Raja Abd;Noor, Noor Dina Muhd;Ibrahim, Noor Azlina;Salleh, Abu Bakar;Basri, Mahiran
    • Journal of Microbiology and Biotechnology
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    • v.22 no.1
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    • pp.34-45
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    • 2012
  • A thermophilic Bacillus stearothermophilus F1 produces an extremely thermostable serine protease. The F1 protease sequence was used to predict its three-dimensional (3D) structure to provide better insights into the relationship between the protein structure and biological function and to identify opportunities for protein engineering. The final model was evaluated to ensure its accuracy using three independent methods: Procheck, Verify3D, and Errat. The predicted 3D structure of F1 protease was compared with the crystal structure of serine proteases from mesophilic bacteria and archaea, and led to the identification of features that were related to protein stabilization. Higher thermostability correlated with an increased number of residues that were involved in ion pairs or networks of ion pairs. Therefore, the mutants W200R and D58S were designed using site-directed mutagenesis to investigate F1 protease stability. The effects of addition and disruption of ion pair networks on the activity and various stabilities of mutant F1 proteases were compared with those of the wild-type F1 protease.

STUDIES ON THE LEVELS OF INDOLE-3-ACETIC ACID (IAA) AND INDOLE-3-ACETYL-L-ASPARATE(IAAsp)IN RELATION TO SOMATIC EMBRYOGENESIS OF CALLI DERIVED FROM GINSENG (PANAX GINSENG C.A. MEYER) ROOTS (인삼근 캘루스의 체세포 배아 발생과 관련한 IAA 및 IAAsp의 수준에 관한 연구)

  • Chen Kai-hsien;Hsing Yue-ie;Chen Shuh-chun;Chang Wei-chin
    • Proceedings of the Ginseng society Conference
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    • 1984.09a
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    • pp.45-48
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    • 1984
  • Ion-pair reverse phase HPLC techniques were used to compare the contents of IAA and IAAsp in the embryogenic and non-embryogenic calli derived from ginseng (Panax ginseng C.A. Meyer) root tissues. The contents of IAA and IAAsp of the embryogenic callus were much higher (7 to 18 X respectively) than those of non-embryogenic callus. There is a distinct fluorescent peak of an unknown component in the HPLC profile of the extract for indolic compounds from non-embryo-genic callus. This distinct difference may be employed as a promising parameter to screen the culture pieces for obtaining the calli with high potential for embryoid formation.

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Chronic saponin treatment attenuates damage to the pancreas in chronic alcohol-treated diabetic rats

  • Choi, Mi Ran;Kwak, Su Min;Bang, Sol Hee;Jeong, Jo-Eun;Kim, Dai-Jin
    • Journal of Ginseng Research
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    • v.41 no.4
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    • pp.503-512
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    • 2017
  • Background: Chronic heavy alcohol consumption may raise the risk of developing type 2 diabetes mellitus. Saponins inhibit apoptosis of pancreatic islet cells and reduce lipid parameters. The present study was designed to investigate the effect of saponin on chronic ethanol-treated diabetic rats. Methods: Long-Evans Tokushima Fatty (LETO) and Otsuka Long-Evans Tokushima Fatty (OLETF) rats were pair-fed a Lieber-DeCarli diet with and without 5% ethanol for 12 wks. Two weeks after starting the pair-feeding with the Lieber-DeCarli diet, intraperitoneal injection of saponin was performed for 10 wks. To perform the experiments, rats were divided as follows: LETO-Control (LC), LETO-Ethanol (LE), LETO-Ethanol-Saponin (LES), OLETF-Control (OC), OLETF-Ethanol (OE), and OLETF-Ethanol-Saponin (OES). Results: The weights of epididymal and mesenteric fat tissue in LES and OES rats were the lightest from among the LETO and OLETF groups, respectively. The secretion of alanine aminotransferase and cholesterol in OES rats decreased significantly compared to their secretion in OC and OE rats, respectively. The islets of the pancreas in LE and OE rats showed clean, unclear, and smaller morphology compared to those of LC, LES, OC, and OES rats. In addition, the expression of insulin in the islets of the pancreas in LC, LES, OC, and OES rats was higher than in LE and OE rats. Conclusion: Saponin may not only be helpful in alleviating the rapid progress of diabetes due to chronic alcohol consumption in diabetic patients, but may also show potential as an antidiabetic drug candidate for diabetic patients who chronically consume alcohol.

Additional axial K-wire Fixation for Proximal Crescentic Metatarsal Osteotomy : A Biomechanical Study (반월형 근위 중족골 절골술에 대한 보강적 축성 K-강선 고정술 : 생체역학적 연구)

  • Jung, Hong-Geun;Kim, You-Jin;Guyton, Gregory
    • Journal of Korean Foot and Ankle Society
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    • v.7 no.2
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    • pp.151-156
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    • 2003
  • Purpose: Proximal crescentic metatarsal osteotomy(PMO) is one of the most common procedures for correcting moderate to severe degree hallux valgus deformity. Although screw fixation is used for osteotomy site stability, loss of reduction can occur. The purpose of this study is to compare the sagittal plane stability of the conventional crescentic PMO fixed with a single screw with that of the crescentic PMO fixed with 1 screw and 2 supplemental K -wires. Material and Methods: Ten matched pairs of cadaveric foot specimens were used for the proximal crescentic metatarsal osteotomy. For one foot specimen of each pair, crescentic osteotomy was fixed with 4mm long threaded cannulated screw, while the matched pair was prepared by adding two axial 1.6mm K-wires to the conventionally fixed 4mm screw. The extensometer was used to measure the osteotomy gap as the metatarsal head was loaded continuously until failure using a servohydraulic MTS Mini Bionix test frame. The strength of fixation was normalized with the bone mineral density (BMD) of the paired specimen $(N{\times}cm^{2}/gm)$, Result: The average strength of the crescentic PMO with axial K-wire fixation ($458.8cm^{2}/gm$, S.D. 434.3) was significantly higher than the standard crescentic PMO ($367.5cm^{2}/gm$, S.D. 397,9) (p=0.05). Conclusion: Supplemental fixation with two axial K-wires can be added to the crescentic PMO to enhance the initial fixation stability to prevent the loss of reduction or dorsal malunion.

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