• Title/Summary/Keyword: high-level resistant

Search Result 296, Processing Time 0.028 seconds

Toxicological Test Methods and AChE Inhibition of Organophosphorus Acaricides of Twospotted Spider Mite, Tetranychus urticae (점박이응애의 독성 시험방법과 유기인계 살비제 AChE 활성저해에 관한 연구)

  • 김도익;이승찬
    • Korean journal of applied entomology
    • /
    • v.31 no.1
    • /
    • pp.1-6
    • /
    • 1992
  • These studies were carried out to compare toxicological test methods of two spotted spider mite, Tetranychus urticae Koch,; and to investigate relationship between in vivo resistant level of highly acaricide-selected population, and in vitro insensitivity of the AChE in the same population to carbophenothion and ethion. The slide dip method (CV = 8.7%) was of more accuracy and suitability than that of the leaf dip method(CV=12.2%) and leaf disc method (CV= 13.6 %) in determination of the resistant levels of twospotted spider mite to acaricides. The slide dip method also had the advantages of simple treatment with different populations on a slide at the same time, standardization of post-treatement conditions and living plants exclud¬ed from the test. Even though the topical application method(CV =8.1 %) showed high accuracy, it had the demerits of the much time consuming, need of expensive equipment and difficulty of test manipulation. For a limited time, the 22nd successive carbophenothion-selected population of two-spotted spider mite showed 156- and 128-fold resistant levels to carbophenothion and ethion(both alPs), respectively. However, the 24th successive ethion-selected population revealed 64.1- and 65-fold resistant levels to ethion and carbophenothion, respectively. In the inhibition of AChE activity, the carbophenothion-selected population showed 3.3- and 2.7-fold insensitivity in AChE activity to carbophenothion and ethion, respectively. Likewise, the ethion -selected population exhibited 3- and 2.6-fold insensitivity in AChE activity to carbophenothion and ethion, respectively, as compared with that of susceptible population. As a result, a good relation was recognized between in vivo resistance to organophosphorous acaricides and in vitro insensitivity of the AChE to corresponding inhibitors.

  • PDF

Screening of Tomato Cultivars Resistant to Bacterial Wilts (풋마름병 저항성 토마토 품종 선발)

  • Han, You-Kyoung;Min, Ji-Seon;Park, Jong-Han;Han, Kyung-Sook;Kim, Dae-Hyun;Lee, Jung-Sup;Kim, Hyeong-Hwan
    • Research in Plant Disease
    • /
    • v.15 no.3
    • /
    • pp.198-201
    • /
    • 2009
  • Bacterial wilts, caused by Ralstonia solanacearum, is a very destructive disease to tomato plants (Solanum lycopersicum) in Korea. Selection of resistant cultivar is the best way to prevent or reduce the occurrence of this disease. Thirty-nine tomato cultivars, twenty-one cherry tomato cultivars and thirteen rootstock tomato cultivars were inoculated with Ralstonia solanacearum, to evaluate tomato cultivars for resistance against bacterial wilts. Thirty-seven cultivars were highly susceptible to bacterial wilts and 61-100% of their whole tissue became wilted within 10 days after inoculation. Twenty-four cultivars showed moderate resistance and twelve were resistant to bacterial wilts. In an evaluation of 73 major commercial cultivars, 'Lilyance', 'TP-7', 'Choice', 'Dadaki', 'Akiko', 'Redstar', 'Match', 'B-blocking', 'Magnet', 'Support', 'Friend' and 'Special' were found to have a high level of resistance to bacterial wilts of tomatoes.

A Study on the Construction Performance of Curtain Wall Systems Using Fire-Resistant & Light-Weight Inorganic Composite Foam Board (내화성 경량 무기 발포보드를 이용한 커튼월 시스템의 시공성능에 관한 연구)

  • Koo, Young-Ah;Kim, Seong-Eun;Oh, Chang-Won
    • Journal of the Korea Institute of Building Construction
    • /
    • v.14 no.2
    • /
    • pp.127-134
    • /
    • 2014
  • This study had the goal of analyzing the economic feasibility and constructability of a fire resistant curtain wall system using Light-weight Inorganic Composite Foam Board(LI-CFB). LI-CFBs, new materials with excellent fire resistance are being developed for use as the back panel of curtain wall and their fire resistance has already been analyzed through actual tests in earlier studies. In this study, a mock-up test involving the installation of the fire resistant curtain wall system on an actual building was conducted, and the system was compared with a common curtain wall system. This system is applied in the same way as a common curtain wall system. But the cutting LI-CFBs, which are brought from a factory, are used in the system and attached on the frame (mullion and transom). Even though the system requires more working time than the existing system, the LI-CFBs back panels are easy to cut and do not produce dust. Also, the panels are able to be assured the quality by checking damaged parts easily. Besides having a high level of fire resistance, the system's economic feasibility and constructability meets or exceeds those of the existing system.

The Preclinical Study of Hyeolbuchugeo-tang (Xuefuzhuyu-tang) on Bone Healing in Rats with Rib Fracture (골절 유발 Rat에 대한 혈부축어탕(血府逐瘀湯)의 전임상 연구)

  • Huh, Gun;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.30 no.3
    • /
    • pp.23-44
    • /
    • 2020
  • Objectives The purpose of this study is to evaluate the healing effect of Hyeolbuchugeo-tang (HC) in rats with rib fracture. Methods Rats were randomly divided into 5 groups (naive, control, positive control, HC-L and HC-H). All groups except naive group were subjected to bone fracture of rib. Naive group received no treatment at all. Control group was fed with phosphate buffered saline. Positive control group was orally medicated with tramadol. Experimental group was orally medicated with HC extract (50 mg/kg for low concentration [HC-L], 100 mg/kg for high concentration [HC-H]). X-ray and micro-computed tomography (micro-CT) were conducted to assess the effect of HC. We analysed the level of 2) transforming growth factor-β1 (TGF-β1), Ki67, alkaline phosphatase (ALP), receptor activator of nuclear factor kappa-β, runt-related transcription factor 2 (Runx2) and tartrate resistant acid phosphatase (TRAP) on 7 and 14 days after fracture. ALP, alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen, creatinine was measured for safety assessment. Results X-ray and micro-CT, showed HC enhance bone repair process. Callus formation was increased in experimental group at 7 days after fracture, but decreased at 14 days after fracture. 7 days after fracture, the level of TGF-β1 in experimental group was decreased. The level of Ki67, Runx2 in HC-H, TRAP in HC-L was increased. 14 days after fracture, the level of Ki67 in HC-L and HC-H was decreased. The level of ALP, Runx2, BUN in HC-L, TRAP in HC-L and HC-H was increased. Conclusions Taken together the results, HC promoted healing of bone fracture. In conclusion, HC has a potential to promote healing of bone fracture.

Contamination Rates in Duodenoscopes Reprocessed Using Enhanced Surveillance and Reprocessing Techniques: A Systematic Review and Meta-Analysis

  • Shivanand Bomman;Munish Ashat;Navroop Nagra;Mahendran Jayaraj;Shruti Chandra;Richard A Kozarek;Andrew Ross;Rajesh Krishnamoorthi
    • Clinical Endoscopy
    • /
    • v.55 no.1
    • /
    • pp.33-40
    • /
    • 2022
  • Background/Aims: Multiple outbreaks of multidrug-resistant organisms have been reported worldwide due to contaminated duodenoscopes. In 2015, the United States Food and Drug Administration recommended the following supplemental enhanced surveillance and reprocessing techniques (ESRT) to improve duodenoscope disinfection: (1) microbiological culture, (2) ethylene oxide sterilization, (3) liquid chemical sterilant processing system, and (4) double high-level disinfection. A systematic review and meta-analysis was performed to assess the impact of ESRT on the contamination rates. Methods: A thorough and systematic search was performed across several databases and conference proceedings from inception until January 2021, and all studies reporting the effectiveness of various ESRTs were identified. The pooled contamination rates of post-ESRT duodenoscopes were estimated using the random effects model. Results: A total of seven studies using various ESRTs were incorporated in the analysis, which included a total of 9,084 post-ESRT duodenoscope cultures. The pooled contamination rate of the post-ESRT duodenoscope was 5% (95% confidence interval [CI]: 2.3%-10.8%, inconsistency index [I2]=97.97%). Pooled contamination rates for high-risk organisms were 0.8% (95% CI: 0.2%-2.7%, I2=94.96). Conclusions: While ESRT may improve the disinfection process, a post-ESRT contamination rate of 5% is not negligible. Ongoing efforts to mitigate the rate of contamination by improving disinfection techniques and innovations in duodenoscope design to improve safety are warranted.

Prevalence and Clinical Outcome of Penicillin-resistant Pneumococcal Pneumonia (폐렴구균에 의한 지역사회 획득 폐렴에서 페니실린 내성률과 내성에 따른 임상경과에 관한 연구)

  • Hong, Ji Hyun;Lee, Hyung Seok;Jung, Seung Hyun;Kim, Gyu Won;Eom, Kwang-Seok;Lee, Jae Myung;Jang, Seung Hun;Kim, Dong Gyu;Hyoen, In Gyou;Lee, Myoung Koo;Park, Yong Bum;Jung, Ki-Suck;Lee, Young Kyoung
    • Tuberculosis and Respiratory Diseases
    • /
    • v.54 no.3
    • /
    • pp.295-303
    • /
    • 2003
  • Backgroung : The incidence of penicillin-resistant streptococcus pneumoniae(PRSP) accounts for almost 70% of all pneumococcal pneumonia cases in Korea. It is still unclear as to whether the efficacy of penicillin or equally active beta-lactam agents is compromised in PRSP pneumonia. This study investigated the prevalence of PRSP in community-acquired pneumonia and its clinical course. Methods : A total of 42 patients with community-acquired pneumococcal pneumonia were evaluated from July 1999 to May 2001. The cultured strains of Streptococcus pneumoniae were divided into susceptible, intermediately resistant, and resistant strains by an E-test, and the effect of the clinical course was investigated. Results : From a total of 42 patients, 22 (52.4%) patients had an intermediate resistance (MIC $0.1-1{\mu}g/m{\ell}$) and six (14.3%) showed a high resistance ($MIC{\geq}2.0{\mu}g/m{\ell}$) with current penicillin susceptibility categories. However, according to the classification of the DRSPTWG (Drug Resistant Streptococcus pneumoniae Therapeutic Working Group), there were 11 cases (26.2%) of intermediate resistance and no case of high resistance. Under empirical antimicrobial treatment, there was no difference in the clinical outcome between the penicillin susceptible and resistant group. Conclusion : The clinical outcome of PRSP pneumonia with empirical therapy was acceptable. These results suggest that the current MIC breakpoint for penicillin resistance in Streptococcus pneumoniae has been set at a very low level and penicillin resistance according to the NCCLS classification does not significantly influence the outcome of the empirical treatment for pneumococcal pneumonia.

Effect of Resistant Starch on the Large Bowel Environment and Plasma Lipid in Rats with Loperamide-Induced Constipation (저항전분 투여가 Loperamide 유도 변비 쥐의 대장환경과 혈청지질에 미치는 효과)

  • Sin, Hyun-Ju;Kim, Kwang-Ok;Kim, Sung-Hong;Kim, Young-Ah;Lee, Hye-Sung
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.39 no.5
    • /
    • pp.684-691
    • /
    • 2010
  • The present study was conducted to evaluate the effect of resistant starch (RS) on the large bowel function and plasma lipids in rats with constipation induced by Loperamide. Animals were divided into six groups: normal control-5% cellulose, constipation-5% cellulose, constipation-5% pectin, constipation-5% RS-type 2 (RS2), constipation-8% RS2 and constipation-5% RS type 3 (RS3) groups, and fed experimental diets for five weeks. The results from RS groups were compared with those from other dietary fiber groups. The groups supplemented with RS3 or high level of RS2 showed significantly increased counts of bifidobacteria in the cecum than the other groups. The production of total short chain fatty acids in the cecal contents was significantly high in pectin, RS3 and high RS2 groups. The pH in the cecal contents of the RS supplemented groups was significantly decreased compared with the cellulose supplemented groups. The production of prostaglandin E2 in the colon mucus of the RS groups was higher than the normal group; however, it was significantly decreased compared to the cellulose or pectin supplemented constipated groups. The thickness of the mucus layer and the production of mucus from epithelial cells were significantly increased in RS3 group compared to the constipated cellulose group. Supplementation of resistant starch significantly elevated the ratio of HDL-cholesterol to total cholesterol and significantly lowered plasma atherogenic index compared with cellulose or pectin supplementation in constipated rats. The results of the present study demonstrated that resistant starch supplementation may help in improving the large bowel environment by stimulation of bifidobacterial proliferation, reduction of pH and inflammation factor and by increased production of mucus. It has also been found that an additional health benefit is improvement in lipid levels of serum.

Highly dispersive substitution box (S-box) design using chaos

  • Faheem, Zaid Bin;Ali, Asim;Khan, Muhamad Asif;Ul-Haq, Muhammad Ehatisham;Ahmad, Waqar
    • ETRI Journal
    • /
    • v.42 no.4
    • /
    • pp.619-632
    • /
    • 2020
  • Highly dispersive S-boxes are desirable in cryptosystems as nonlinear confusion sublayers for resisting modern attacks. For a near optimal cryptosystem resistant to modern cryptanalysis, a highly nonlinear and low differential probability (DP) value is required. We propose a method based on a piecewise linear chaotic map (PWLCM) with optimization conditions. Thus, the linear propagation of information in a cryptosystem appearing as a high DP during differential cryptanalysis of an S-box is minimized. While mapping from the chaotic trajectory to integer domain, a randomness test is performed that justifies the nonlinear behavior of the highly dispersive and nonlinear chaotic S-box. The proposed scheme is vetted using well-established cryptographic performance criteria. The proposed S-box meets the cryptographic performance criteria and further minimizes the differential propagation justified by the low DP value. The suitability of the proposed S-box is also tested using an image encryption algorithm. Results show that the proposed S-box as a confusion component entails a high level of security and improves resistance against all known attacks.

Study on the alternatives to trace the origin and to diminish the sediments of drinking water (수돗물의 앙금발생규명 및 저감기술방안)

  • 김갑수;임병진;권은미
    • Journal of environmental and Sanitary engineering
    • /
    • v.9 no.1
    • /
    • pp.17-28
    • /
    • 1994
  • There are many possibilities that may lead to low quality of drinking water Recently, some unknown deposits in tap water raised a lot of public concern regarding the safety of drinking water in Seoul. We analyzed the quality of tap water from several areas of Seoul, including the area where public complaints about tap water were high. The results shows that the quality of tap water in Seoul was good, well below the environmental standards. Only the tap water from the area with high public complaints showed turbidity higher than that of other area. Also, result shows that component of deposit in tap water was Al, Fe, Mn, and Zn. Based on the research result we propose several measures that might help to reduce the amount of deposit in tap water as follows : 1 Using coagulant aid when coagulating or adjusting pH when filtering. 2. Replacing old water pipeline with new corrosive- resistant one. 3. Increasing water treatment efficiency by enhancing water treatment system such as automation of water treatment system adjusting production capacity, and improving operational condition of filler basin. 4. Chlorine disinfection at the distribution reservoir would help maintaining the same pH level and chlorine concentration throughout the water pipeline and reduce corrosion of pipe.

  • PDF

The feature of Microcapsule Involving Ultraviolet Rays Absorbent

  • Ueda, Yuka;Segawa, Akihiro;Murakoshi, Noriyuki;Hayashi, Natsuko;Yoshioka, Masato
    • Proceedings of the SCSK Conference
    • /
    • 2003.09a
    • /
    • pp.417-430
    • /
    • 2003
  • A new method was developed to prepare microcapsules involving hydrophobic components. A totally new "silicone-resin-polypeptide" was used as the wall materials. The polypeptide was made by hydrolysis of collagen and silk protein and so on, and that was combined with silicone. This microcapsule was easily prepared from silicone-resin-polypeptide in water solution. The ratio of encapsulation in the microcapsule was not only high level as 90%, which had never been reached, but also the particle size could be controlled to obtain very small size (average particle size: 2${\mu}{\textrm}{m}$). Moreover, these microcapsules were resistant to high shearing forces and were stable over a long time period. This stable microcapsule was not crushed in pressure with finger spreading, so the core materials hardly touch the skin directly. Application in cosmetics by using microcapsule involving UV absorbents (2-ethylhexy1-4-methoxycinnamate (OMC) and 4-tert-butyl-4' -methoxydibenzoyl-methane (BMDBM)) was examined. It was possible to apply organic UV absorbents in water-rich formulations without any surfactant by using this microcapsule. This formulation demonstrated a good moisturizing and soft skin feel. Therefore, the microcapsule was applied to hair care products. As a result, the sunscreen hair lotion with microcapsule was able to prevent from damaging and decoloring of hair color by UV rays. As just, it was suggested that this microcapsules were be widely applied in cosmetics.cosmetics.

  • PDF