• 치위생과학회지
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• 제10권6호
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• pp.431-438
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• 2010

본 연구는 치과위생사를 감정노동 종사자로 보고 감정노동의 중요성을 인식하여 치과위생사의 감정노동 정도를 확인하고, 일반적인 특성, 직무관련 특성, 건강관련 특성 및 중재요인(직무만족도, 사회적 지원), 반응요인(피로)이 치과위생사의 감정노동에 어느 정도 영향을 미치는지 파악하기 위해 시도되었다. 전남 북 지역의 치과병원에 근무하는 치과위생사를 대상으로 2010년 3월부터 2010년 7월까지 자기기입식 설문조사 방식으로 213부의 설문지를 수집하여 SPSS 12.0 프로그램을 이용하여 분석하였다. 1. 치과위생사의 감정노동의 수준은 중등도 이상의 감정노동 수준을 보이고 있었으며, 하위 요인 중 감정표현의 정도, 환자응대, 진심행위 등의 순으로 나타났다. 2. 제 특성에 따른 감정노동의 수준 및 분포는 24세 이하, 미혼, 치과위생사 경력이 2년 이하, 근무시간이 8~9시간, 비흡연자, 규칙적인 운동을 하지 않으며, 음주를 하고, 직무만족도가 낮고(직무불만족도가 높고), 사회적 지원이 낮다고 느끼는 치과위생사의 경우 감정노동의 수준이 높은 부류($Q_2$, High)에서 분포 및 수준이 높게 나타났다. 3. 치과위생사의 감정노동수준과 직무만족, 사회적지원, 피로 변수들 간의 상관관계를 분석한 결과 사이에는 유의한 상관관계를 보였으며 직무만족이 낮고(직무불만족이 높고), 사회적지원이 불충분하고, 피로를 많이 느낄수록 감정노동의 수준이 높은 것으로 나타났다. 4. 치과위생사의 감정노동 수준에 미치는 요인을 중회귀분석한 결과 "사회적 지원", "치과위생사 경력", "직무만족", "근무자 수", "나이", "방문 환자수", "결혼" 항목 순으로 유의하게 영향을 미치는 것으로 분석되었으며 설명력은 82.3%이었다. 이상의 결과를 기초로 치과위생사의 감정노동 수준 및 감정노동에 영향을 미치는 요인 분석을 실시한 결과 중등도 이상의 감정노동수준을 보이고 있는 것으로 나타났다. 감정노동 수준에 영향을 미치는 중요 요인은 "나이", "결혼", "치과위생사 경력" 등 개인적 요인과 "사회적 지원", "직무만족", "근무자 수", "방문 환자수" 등 병원 근무환경과 병원근무자들 사이의 인간적인 관계를 기초로 하는 변수들인 것으로 분석 되었다. 즉, 치과위생사의 직무수행에 따른 감정노동 수준을 저감시키기 위해서는 같이 근무하는 근무자들 사이의 원만한 관계 유지가 중요하며 업무여건을 개선하고 직무만족도를 높일 수 있도록 충분한 치과위생사의 수 확보 등의 대책을 수립해야 할 것으로 판단된다. 나아가 치과위생사의 감정노동의 중요성을 인식하고, 향후 치과위생사 및 병원조직의 감정노동에 대한 이해를 높이고 감정노동을 지속적으로 관리할 수 있는 프로그램 개발이 필요할 것으로 판단된다.

• 대한화장품학회지
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• 제49권3호
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• pp.203-212
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• 2023

본 연구는 땅콩의 부산물로 폐기되는 겉껍질의 기능성 화장품 소재 활용 가능성을 검토하고자 수행하였다. 땅콩 겉껍질 추출물의 DPPH 및 ABTS 라디칼 소거능 및 SOD 유사활성 IC₅₀값은 각각 75.00, 46.33, 및 472.83 ㎍/mL으로 조사되었다. 땅콩 겉껍질 추출물 처리에 따른 MMP-1, MMP-3, 및 procollagen의 단백질 발현 정도를 측정한 결과, 농도 의존적으로 MMPs 단백질 발현량이 감소하였고, procollagen 단백질은 정상대조군 수준을 유지하였다. 주름 억제 효능을 검정한 결과, 추출물의 elastase 및 collagenase 저해활성 IC₅₀ 값은 각각 0.30 및 0.09 mg/mL로 양성대조군보다 낮았다. 땅콩 겉껍질 추출물에서 분리한 eriodictyol과 luteolin의 elastase 및 collagenase 저해 활성을 분석한 결과, 0.1 mg/mL 처리농도에서 eriodictyol과 luteolin은 각각 53.8 및 98.0%의 elastase 저해 활성을 보였으며, collagenase 저해 활성은 각각 60.1 및 72.5%로 조사되었다. 이를 통해 땅콩 겉껍질 추출물의 주름억제활성 유효성분은 luteolin일 것으로 사료되었다. 또한, 땅콩 겉껍질 추출물이 함유된 로션 및 크림 제형의 온도 조건 및 온도 순환에 따른 pH 및 점도를 측정한 결과, 유의미한 변화 없이 안정적인 제형임을 확인하였다. 이를 통해 땅콩 겉껍질 추출물이 주름 억제를 위한 화장품 소재로 적용 가능할 것으로 판단되었다.

• Asia Marketing Journal
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• 제16권1호
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• pp.71-100
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• 2014

While the role of emotional antecedents of effective selling behavior would be important, the issue has not been fully addressed in the sales literature. To fill this gap, we conceptualize and empirically examine the relationships among salesperson's emotional regulation processes such as emotional intelligence (EI) and emotional labor (EL), effective selling behavior, and sales performance on the basis of educational, occupational, social psychology literature and marketing literature (e.g., Henning-Thurau, Groth, Paul, and Gremler 2006; Kidwell et al. 2011; Liu et al. 2008; Mayer, Salovey, and Caruso 2008). First, salesperson's EI is defined as his or her capability that enables correct perceptions about emotional situations in sales interactions. The EI is expected to work as psychological resources for different types of EL (i.e., deep acting and surface acting) to be performed by salesperson as emotional expression strategies (e.g., Lie et al. 2008). It is, then, expected that the features of EL selected by the salesperson would lead to different levels of adaptive selling behavior (ASB) and thereby sales performance (Monaghan 2006). Further, given that salesperson's customer orientation (CO) is found to be an important correlate of ASB (Franke and Park 2006), it is expected that CO would moderate the relationship between EL and ASB (Rozell, Pettijohn, and Parker 2004). Hence, this research attempts to shed additional light on emotionally-driven (EL) as well as cognitively-driven (CO) antecedents of ASB (Frank and Park 2006). The findings of the survey research, done with 336 salespersons in insurance and financial companies, are summarized as follows. First, salespersons with a high level of EI are found to use both deep acting (regulating the emotions themselves) and surface acting (controlling only emotional expressions) in a versatile way, when implementing EL. Second, the more the salesperson performs deep acting, the more he or she shows ASB. It is, then, important for salespersons to use deep acting more frequently in the EL process in order to enhance the quality of interacting with customers through ASB. On the other hand, the salesperson's surface acting did not have a significant relationship with ASB. Moreover, CO was found to moderate the relationship between the salesperson's deep acting and ASB. That is, the context of high CO culture and individual salesperson's deep acting would synergistically make the selling efforts adaptive to customer preferences. Conceptualizing and empirically verifying the antecedent roles of important emotional constructs such as EI and EL in salesperson's effective selling behavior (ASB) and sales performance is a major theoretical contribution in the sales literature. Managerially, this research provides a deeper understanding on the nature of tasks performed by salespersons in service industries and a few guidelines for managing the sales force. First, sales organizations had better consciously assess EI capacity in the selection and nurturing processes of salespersons, given that EI can efficiently drive EL and the resulting effective selling behavior and performance. Further, the concept of EL could provide a framework to understand the salespersons' emotional experiences in depth. Especially, sales organizations may well think over how to develop deep acting capabilities of their sales representatives. In this direction, the training on deep acting strategies would be an essential task for improving effective selling behavior and performance of salespersons. This kind of training had better incorporate the perspectives of customers such that many customers can actually discern whether salespersons are doing either surface acting or deep acting. Finally, based on the synergistic effects of deep acting and CO culture, how to build and sustain CO is always an ever-important task in sales organizations. While the prior sales literature has emphasized the process and structure of highly customer-oriented sales organization, our research not only corroborates the important aspects of customer-oriented sales organization, but also adds the important dimension of competent sales representatives who can resonate with customers by deep acting for sales excellence.

• 한국농공학회지
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• 제17권1호
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• pp.3642-3654
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• 1975

The purpose of this thesis is to derive a unit hydrograph which may be applied to the ungaged watershed area from the relations between directly measurable unitgraph properties such as peak discharge(qp), time to peak discharge (Tp), and lag time (Lg) and watershed characteristics such as river length(L) from the given station to the upstream limits of the watershed area in km, river length from station to centroid of gravity of the watershed area in km (Lca), and main stream slope in meter per km (S). Other procedure based on routing a time-area diagram through catchment storage named Instantaneous Unit Hydrograph(IUH). Dimensionless unitgraph also analysed in brief. The basic data (1969 to 1973) used in these studies are 9 recording level gages and rating curves, 41 rain gages and pluviographs, and 40 observed unitgraphs through the 9 sub watersheds in Nak Oong River basin. The results summarized in these studies are as follows; 1. Time in hour from start of rise to peak rate (Tp) generally occured at the position of 0.3Tb (time base of hydrograph) with some indication of higher values for larger watershed. The base flow is comparelatively higher than the other small watershed area. 2. Te losses from rainfall were divided into initial loss and continuing loss. Initial loss may be defined as that portion of storm rainfall which is intercepted by vegetation, held in deppression storage or infiltrated at a high rate early in the storm and continuing loss is defined as the loss which continues at a constant rate throughout the duration of the storm after the initial loss has been satisfied. Tis continuing loss approximates the nearly constant rate of infiltration (${\Phi}$-index method). The loss rate from this analysis was estimated 50 Per cent to the rainfall excess approximately during the surface runoff occured. 3. Stream slope seems approximate, as is usual, to consider the mainstreamonly, not giving any specific consideration to tributary. It is desirable to develop a single measure of slope that is representative of the who1e stream. The mean slope of channel increment in 1 meter per 200 meters and 1 meter per 1400 meters were defined at Gazang and Jindong respectively. It is considered that the slopes are low slightly in the light of other river studies. Flood concentration rate might slightly be low in the Nak Dong river basin. 4. It found that the watershed lag (Lg, hrs) could be expressed by Lg=0.253 (L.Lca)0.4171 The product L.Lca is a measure of the size and shape of the watershed. For the logarithms, the correlation coefficient for Lg was 0.97 which defined that Lg is closely related with the watershed characteristics, L and Lca. 5. Expression for basin might be expected to take form containing theslope as {{{{ { L}_{g }=0.545 {( { L. { L}_{ca } } over { SQRT {s} } ) }^{0.346 } }}}} For the logarithms, the correlation coefficient for Lg was 0.97 which defined that Lg is closely related with the basin characteristics too. It should be needed to take care of analysis which relating to the mean slopes 6. Peak discharge per unit area of unitgraph for standard duration tr, ㎥/sec/$\textrm{km}^2$, was given by qp=10-0.52-0.0184Lg with a indication of lower values for watershed contrary to the higher lag time. For the logarithms, the correlation coefficient qp was 0.998 which defined high sign ificance. The peak discharge of the unitgraph for an area could therefore be expected to take the from Qp=qp. A(㎥/sec). 7. Using the unitgraph parameter Lg, the base length of the unitgraph, in days, was adopted as {{{{ {T}_{b } =0.73+2.073( { { L}_{g } } over {24 } )}}}} with high significant correlation coefficient, 0.92. The constant of the above equation are fixed by the procedure used to separate base flow from direct runoff. 8. The width W75 of the unitgraph at discharge equal to 75 per cent of the peak discharge, in hours and the width W50 at discharge equal to 50 Per cent of the peak discharge in hours, can be estimated from {{{{ { W}_{75 }= { 1.61} over { { q}_{b } ^{1.05 } } }}}} and {{{{ { W}_{50 }= { 2.5} over { { q}_{b } ^{1.05 } } }}}} respectively. This provides supplementary guide for sketching the unitgraph. 9. Above equations define the three factors necessary to construct the unitgraph for duration tr. For the duration tR, the lag is LgR=Lg+0.2(tR-tr) and this modified lag, LgRis used in qp and Tb It the tr happens to be equal to or close to tR, further assume qpR=qp. 10. Triangular hydrograph is a dimensionless unitgraph prepared from the 40 unitgraphs. The equation is shown as {{{{ { q}_{p } = { K.A.Q} over { { T}_{p } } }}}} or {{{{ { q}_{p } = { 0.21A.Q} over { { T}_{p } } }}}} The constant 0.21 is defined to Nak Dong River basin. 11. The base length of the time-area diagram for the IUH routing is {{{{C=0.9 {( { L. { L}_{ca } } over { SQRT { s} } ) }^{1/3 } }}}}. Correlation coefficient for C was 0.983 which defined a high significance. The base length of the T-AD was set to equal the time from the midpoint of rain fall excess to the point of contraflexure. The constant K, derived in this studies is K=8.32+0.0213 {{{{ { L} over { SQRT { s} } }}}} with correlation coefficient, 0.964. 12. In the light of the results analysed in these studies, average errors in the peak discharge of the Synthetic unitgraph, Triangular unitgraph, and IUH were estimated as 2.2, 7.7 and 6.4 per cent respectively to the peak of observed average unitgraph. Each ordinate of the Synthetic unitgraph was approached closely to the observed one.

• Asia pacific journal of information systems
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• 제19권4호
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• pp.125-148
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• 2009

UGC(User Generated Contents) is emerging as the center of e-business in the web 2.0 era. The trend reflects changing roles of users in production and consumption of contents on websites and helps us to understand new strategies of websites such as web portals and social network websites. Nowadays, we consume contents created by other non-professional users for both utilitarian (e.g., knowledge) and hedonic values (e.g., fun). Also, contents produced by ourselves (e.g., photo, video) are posted on websites so that our friends, family, and even the public can consume those contents. This means that non-professionals, who used to be passive audience in the past, are now creating contents and share their UGCs with others in the Web. Accessible media, tools, and applications have also reduced difficulty and complexity in the process of creating contents. Realizing that users create plenty of materials which are very interesting to other people, media companies (i.e., web portals and social networking websites) are adjusting their strategies and business models accordingly. Increased demand of UGC may lead to website visits which are the source of benefits from advertising. Therefore, they put more efforts into making their websites open platforms where UGCs can be created and shared among users without technical and methodological difficulties. Many websites have increasingly adopted new technologies such as RSS and openAPI. Some have even changed the structure of web pages so that UGC can be seen several times to more visitors. This mainstream of UGCs on websites indicates that acquiring more UGCs and supporting participating users have become important things to media companies. Although those companies need to understand why general users have shown increasing interest in creating and posting contents and what is important to them in the process of productions, few research results exist in this area to address these issues. Also, behavioral process in creating video UGCs has not been explored enough for the public to fully understand it. With a solid theoretical background (i.e., theory of implementation intentions), parts of our proposed research model mirror the process of user behaviors in creating video contents, which consist of intention to upload, intention to edit, edit, and upload. In addition, in order to explain how those behavioral intentions are developed, we investigated influences of antecedents from three motivational perspectives (i.e., intrinsic, editing software-oriented, and website's network effect-oriented). First, from the intrinsic motivation perspective, we studied the roles of self-expression, enjoyment, and social attention in forming intention to edit with preferred editing software or in forming intention to upload video contents to preferred websites. Second, we explored the roles of editing software for non-professionals to edit video contents, in terms of how it makes production process easier and how it is useful in the process. Finally, from the website characteristic-oriented perspective, we investigated the role of a website's network externality as an antecedent of users' intention to upload to preferred websites. The rationale is that posting UGCs on websites are basically social-oriented behaviors; thus, users prefer a website with the high level of network externality for contents uploading. This study adopted a longitudinal research design; we emailed recipients twice with different questionnaires. Guided by invitation email including a link to web survey page, respondents answered most of questions except edit and upload at the first survey. They were asked to provide information about UGC editing software they mainly used and preferred website to upload edited contents, and then asked to answer related questions. For example, before answering questions regarding network externality, they individually had to declare the name of the website to which they would be willing to upload. At the end of the first survey, we asked if they agreed to participate in the corresponding survey in a month. During twenty days, 333 complete responses were gathered in the first survey. One month later, we emailed those recipients to ask for participation in the second survey. 185 of the 333 recipients (about 56 percentages) answered in the second survey. Personalized questionnaires were provided for them to remind the names of editing software and website that they reported in the first survey. They answered the degree of editing with the software and the degree of uploading video contents to the website for the past one month. To all recipients of the two surveys, exchange tickets for books (about 5,000~10,000 Korean Won) were provided according to the frequency of participations. PLS analysis shows that user behaviors in creating video contents are well explained by the theory of implementation intentions. In fact, intention to upload significantly influences intention to edit in the process of accomplishing the goal behavior, upload. These relationships show the behavioral process that has been unclear in users' creating video contents for uploading and also highlight important roles of editing in the process. Regarding the intrinsic motivations, the results illustrated that users are likely to edit their own video contents in order to express their own intrinsic traits such as thoughts and feelings. Also, their intention to upload contents in preferred website is formed because they want to attract much attention from others through contents reflecting themselves. This result well corresponds to the roles of the website characteristic, namely, network externality. Based on the PLS results, the network effect of a website has significant influence on users' intention to upload to the preferred website. This indicates that users with social attention motivations are likely to upload their video UGCs to a website whose network size is big enough to realize their motivations easily. Finally, regarding editing software characteristic-oriented motivations, making exclusively-provided editing software more user-friendly (i.e., easy of use, usefulness) plays an important role in leading to users' intention to edit. Our research contributes to both academic scholars and professionals. For researchers, our results show that the theory of implementation intentions is well applied to the video UGC context and very useful to explain the relationship between implementation intentions and goal behaviors. With the theory, this study theoretically and empirically confirmed that editing is a different and important behavior from uploading behavior, and we tested the behavioral process of ordinary users in creating video UGCs, focusing on significant motivational factors in each step. In addition, parts of our research model are also rooted in the solid theoretical background such as the technology acceptance model and the theory of network externality to explain the effects of UGC-related motivations. For practitioners, our results suggest that media companies need to restructure their websites so that users' needs for social interaction through UGC (e.g., self-expression, social attention) are well met. Also, we emphasize strategic importance of the network size of websites in leading non-professionals to upload video contents to the websites. Those websites need to find a way to utilize the network effects for acquiring more UGCs. Finally, we suggest that some ways to improve editing software be considered as a way to increase edit behavior which is a very important process leading to UGC uploading.

• 대한간호학회지
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• 제26권2호
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• pp.257-270
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• 1996

Studies on menstruation have focused only on menstruation itself and menstrual disorders. The menstruating girls or women have been neglected. So, the purpose of this study was to understand menstrual experience of adolescent girls in their perspective and build a theory on it, The specific purpose of this study were to find initial reaction of the girls, their strategies to adapt to menstruation. consequences of their efforts, influencing factor, and patterns of experience. The subjects of this study were eleven adolescent girls who experienced menarche three months to twenty-six months before the interview time. They were selected purposively. Their ages were in range of twelve and sixteen. One of them was a elementary school girl, three high school girls, and seven middle school girls. Two girls were handicapped because of cerebral palsy. All of them had some knowledge about menstrual physiology and hygiene during menstruation. Data were collected from September, 1994 to July, 1995. Data collection ＆ analysis were done according to the grounded theory methodology by Strauss ＆ Corbin(1990). Data collecting method was the long interviews and observation. Each interview took from 1 hour to 2 hours. Interview were tape-recorded and transcribed later by author. Data were analyzed immediately after interviews. Based on the results of previous interview, next interview were planned until gathered data reached the saturation point. Results were as follows. One hundred and six concepts were found. Those concepts were grouped into twenty eight categories and then fourteen higher categories. Twenty eight categories were as follows. “want to hide”, “bewildered”, “sense of burden”, “sense of heterogeneity”. “gladness”. “sense of superiority”, “negative empathy”, “positive empathy”, “limited hygenic control”, “sense of timing”, “lack of knowledge”, “lack of support”, “advance knowledge”, “informational support”, “emotional support”, “endurance”, “prayer”, “disclosing”, “avoidance”, “diversion”, “sense of powerlessness”, “discovery of sex identity”, “sense of maturation”, “sense of stability”, “acceptance of menstruation ”. fourteen higher categories were as follows. “negative feeling”, “posive feeling”, “exchange of feeling”, “limited hygenic control”, “sense of timing”, “accumulated experience”, “dysmenorrhea”, “level of knowledge”, “need for support”, “perceived support”, “sharing of feeling”, “self-control”, “passive acceptance”, “active acceptance”. The core category was “emotional shaking”, which consisted of “positive feeling” and “negative feeling”. “Emotional shaking”comes up to every adolescent girls experiencing menarche, independently of any contextual conditions, and its dimension has two directions : positive one and negative one. Its influencing factors were time of menarche, advance knowledge, support from the significant persons, expression and self-regulation. Even if they showed different process of adaptation to menstruation, general process of adaptation were as follows : 1. stage of emotional shaking 2. stage of acceptance 3. stage of internalization of the menstrual experience. Seven patterns existed on the process of adaptation to menstruation after menarche. Those are as follows. 1. If girls thought their menarche came too early and they had not much knowledge on menstruation, they had a kind of negative feeling. If they did not get enough support and dysmenorrhea superimposed, they came to accept menstruation passively. 2. If girls had menarche too early. they had negative feeling, even though they had enough advance knowledge. But support helped them accept menstruation easily. 3. If girls had menarche too early, they had negative feeling, even though they had enough advance knowledge on menstruation. But by experiencing subsequent menstruations and disclosing feeling, they began to accept menstruation. 4. If girls had menarche too lately and they had enough advance knowledge on menstruation. they had positive feeling. If dysmenorrhea superimposed later, their feeling turned in to negative one. But they came to accept menstruation positively by disclosing feeling and getting support. 5. If girls had menarche too early, they had negative feeling, even though they had enough advance knowledge on menstruation. In addition to this. if dysmenorrhes superimposed while they did not get enough support, they felt powerless and came to accept menstruation passively. 6. If girls had menarche too early and did not get enough advance knowledge, they had negative feeling. But disclosing feeling and support made them get sense of homogeneity and began to accept menstruation. 7. If girls had handicap, they had negative feeling, even though they had enough advance knowledge and menarche was late. But Menarche made them get feel sexual identity. Their limited hygenic control and negative empathy from their mothers made them accept menstruation passively. To let adolescent girls take their menstrual experience as a part of their lives forming a positive sense of feminine identity, it needs qualified teaching and, support and deep concern of the significant others. Nurses including school nurses should try to develop an educational program, which include menstrual physiology. hygiene during menstrual period, meaning of menstruation and impact of menstruation on the development of female sexual identity.

• 생명과학회지
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• 제16권6호
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• pp.904-910
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• 2006

수지상세포는 종양면역에서 필수적인 강력한 CTL 반응을 개시할 수 있는 유일한 세포이다 . 특히 외인성 종양항원에 대한 CTL 반응 유도는 활성화된 수지상세포의 IL-12 분비를 통한 CD4+ helper T세포의 cross-priming을 필요로 한다. 그러나 최근에 활성화된 수지상세포는 $Th_1$ 면역반응을 유도하지만 활성화 시간이 경과함에 따라 오히려 $Th_2$반응을 유도 할 수 있다. 따라서 본 연구에서는 OVA를 종양항원 모델로 설정하여 종양특이적인 CTL 반응을 형성하기 위한 최적의 수지상세포 활성화 조건을 조사하였다. 마우스 골수세포에 서 수지상세포로의 분화는 항원제시 기능을 위한 표면분자의 발현 측면에서 볼 때 배양 6일-7일 정도가 적합하였다. 수지상세포의 IL-12 생성능은 배양 6일 이상, OVA 항원 탑재 8시간 이상의 경우에 연이은 LPS 성숙자극으로 오히려 감소하는 경향을 보였다. 즉 배양 6일의 수지상세포에 OVA 항원 탑재를 8시간 수행한 경우(8-h DC)가 in vitro에서의 IL-12생성능, ex vivo에서의 세포내 $IFN-{\gamma}$를 발현하는 CD8+ T세포의 증가 및 OVA 특이적인 세포독성효과 등에서 가장 좋은 결과를 보였다. 또한 in vivo에서 종양 치료 및 예방효과에서도 8-h DC로 면역한 경우에 가장 우수한 종양형성 억제 효과와 생존기간 연장효과를 보였다. 현재 대부분의 수지상 세포를 이용한 항종양 백신에서 항원 탑재반응을 24시간 동안 수행하고 있으나, 본 실험의 결과로 볼 때, 8시간의 in vitro 항원 탑재가 보다 효과적인 종양특이적 CTL 반응과 항종양 면역반응을 유도함을 알 수 있다. 결론적으로 본 연구를 통하여 8시간 이상의 항원접촉은 수지상세포의 기능적 활성능력을 오히려 고갈시킬 수 있음을 제시한다.

• Tuberculosis and Respiratory Diseases
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• 제60권6호
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• pp.663-672
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• 2006

연구배경: 미세먼지는 여러 가지 유기물과 무기물의 복합체로 그 구성 성분이 시간과 장소에 따라 다르고 모양과 크기도 일정하지 않으며, 특히 지름 $10{\mu}m$이하의 미세먼지 (particulate matter 10; $PM_{10}$)는 흡입이 가능한 입자의 크기여서 하부기관지 및 폐의 가스-교환부분까지 침착하여 호흡기계에 손상을 일으킬 수 있다. 본 연구에서는 황사에 포함된 $PM_{10}$과 비황사 시기에 포집된 $PM_{10}$이 폐상피세포주에 작용하여 전염증성 사이토카인(proinflammatory cytokine) 및 cytokine messenger RNA(mRNA)의 발현에 어떤 영향이 있는지를 관찰하여 기관지 천식과 만성 폐쇄성 폐질환등 호흡기 질환의 증상 악화기전에 미치는 역할을 규명하고자 하였다. 연구방법: 공기 포집기(HV 500F, sibata model)를 이용하여 황사와 비황사 기간에 하루 6시간씩 실외의 장소에서 대기분진을 membrane filter에 포집한 다음, $PM_{10}$입자를 추출하고 폐암 상피세포주인 A549 cells(한국세포은행주)에 $PM_{10}$을 농도에 맞게($10{\mu}g/ml$, $100{\mu}g/ml$, $500{\mu}g/ml$) 노출시켰다. 각각의 노출된 세포로부터 interleukin(IL)-$1{\alpha}$, $IL-1{\beta}$, IL-8, granulocyte macrophage colony stimulating factor(GM-CSF)의 mRNA를 역전사중합효소연쇄반응(reverse transcriptase polymerase chain reaction; RT-PCR) 방법으로 측정하였다. 결 과: 황사 및 비황사 기간 중 포집된 $PM_{10}$을 가했을 시 가하지 않은 대조군에 비하여 $IL-1{\alpha}$, $IL-1{\beta}$, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF)의 m'RNA와 cytokine의 발현이 유의하게 높았으며, 황사 기간의 고농도의 $PM_{10}$에 노출된 세포의 $IL-1{\alpha}$ mRNA는 비황사 기간의 $PM_{10}$에 노출된 세포의 mRNA보다 증가되어 있었다. 결 론: $PM_{10}$은 A549 cells에서 전염증성 사이토카인의 발현을 증가시키고 비황사 기간보다 황사 기간 중 대기 중에서 채취한 $PM_{10}$에 노출된 A549 cells에서 일부의 전염증성 사이토카인의 mRNA발현을 더욱 증가시키는 것을 알 수 있었다. 따라서 황사 기간의 $PM_{10}$에 의한 일부의 전염증성 사이토카인의 발현 증가가 만성 호흡기 질환의 증상 악화기전에 연관되어 있을 가능성을 시사하였다.

• 종교문화비평
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• 제31호
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• pp.255-287
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• 2017

본고는 한국 가톨릭교회와 개신교의 자살 담론에서 살필 수 있는 언어적 표현과 의례적 행위를 중심으로 자살 관념의 종교적 회로를 분석한다. 자살과 종교의 상관성을 다루는 연구들에서 쉽게 간과되고 있는 부분은 일반 종교인의 자살 관념을 형성하는 종교적 회로와 그 구성 방식이다. 전통 종교들이 자살을 금지하는 믿음 체계를 가지고 있고, 소속된 구성원들은 그러한 믿음체계에 따라 자살에 대한 인식 혹은 관념을 형성하게 된다는 기본 전제는 자살률과 (종교)집단의 상관성을 밝히려는 연구에서 많이 발견된다. 그러나 사적인 차원에서 자살 관념의 종교적 구성 방식을 이해하려면 자살 관념과 정서가 유통되는 종교적 환경에 주목할 필요가 있다. 왜냐하면 일반 신자는 교리나 신학에의해 완벽하게 정의된 자살 관념을 수동적이고 온전하게 수용해서 자신의 것으로 삼지않기 때문이다. 오히려 일반 신자는 종교적 환경에서 떠도는 자살과 관련된 여러 관념의 조각들을 '자신의 삶의 맥락' 속에서 모으고 미완의 형태로 자살 관념을 지니는 경향을 보인다. 그러한 자살 관념의 불안정하고 미완결적인 특성은 자살에 의한 상실의 경험을 겪을 때 확연하게 드러난다. 종교적 믿음을 지닌 자살생존자의 경우에는 교리나 신학에 의해 제시되는 자살의 공식적 규정에 저항하거나 또는 자기의 맥락 속에서 자살 관념을 이해하고자 노력한다. 자살과 관련한 언어적 표현과 의례적 행위를 놓고 볼 때 공적인 영역과 사적인 영역에서 관심의 초점이 다르게 놓여 있음이 발견된다. 가톨릭교회의 경우, 공적 영역에서 가톨릭교회는 한국 사회의 높은 자살률을 고려해서 자살과 자살자에 대한 과거의 부정적인 태도에서 점차 관용적인 태도를 취하지만, 그러한 관용은 자살을 대죄로 규정하는 교리적 윤리적 판단을 넘어서지는 않는다. 이에비해 사적 영역에서 나타나는 신자의 언술과 몸짓에는 간절함, 안타까움, 근심, 불안, 고통 등의 감정이 담겨 있다. 이러한 감정의 언어와 몸짓은 종교적 환경에서 자살자를 위한 종교적 장치를 향해 뻗어가면서 자살의 종교적 회로를 가톨릭교회 내에서 활성화시키고 있다. 개신교의 경우, 한국 개신교에서는 교파주의 및 개교회주의의 제도적 특징과 ${\ll}$바이블${\gg}$에 치중된 해석 기반이 사적 영역에서의 자살의 언어적 표현과 의례 행위에 큰 영향을 주고 있음이 나타난다. 자살에 대한 종교적-윤리적 판단은 신학자나 목회자 개인의 해석에 따라서 상이하게 제시되며, 내면의 신앙과 구원의 확신을 강조하는 개신교의 정서에서 자살 생존자가 감당해야할 복잡한 감정과 심리적 상처를 치유할 수 있는 의례 행위는 크게 활성화되지는 않은 것으로 나타난다.

• 한국철학논집
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• 제32호
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• pp.309-336
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• 2011

본 연구는 성리학과 문화예술이 밀접한 관계에 있다는 데에서 출발하며, 특히 송대에 흥성한 산수화의 발전에 이론적 근거가 되었음을 연구하였다. 성리학은 고대 동양사회의 정치, 경제, 사상, 문화 예술 심지어 생활에 전반에 걸쳐 근간을 이루어 왔던 유학의 새로운 경향이다. 성리학은 중국의 북송(北宋)대 다섯 학자인 주돈이, 소옹, 장재, 정호, 정이가 그 기틀을 새우고 남송(南宋)의 주희가 집대성한 학문이다. 중국의 원(元)나라를 통해 고려후기에 우리나라에 전래되어 조선의 건국의 기틀이 되었고, 퇴계 이황, 율곡 이이를 거쳐 '문화 전반'에 미치지 않은 곳이 없게 되었다. 본 연구에서는 성리학과 예술론과 관계하여 격물치지, '리', 우주의식, '생의', '기상', '예'와 '도'의 관계 등이 산수화와 산수화론을 통해 어떻게 표현되었는지를 연구하였다. 산수화나 화조화에서도 신유학에서 말하는 천지의 '생의'의 미와 '어진 사람은 만물과 더불어 하나'라는 사상을 화폭에 표현하고자 노력하였다. 또한 시와 회화의 통일을 주장하였다. 동양에서는 송대 이전부터도 시와 회화의 관계를 중시했지만, 송에 이르러 시와 회화의 통일을 이루게 된다. 예를 들어, 명나라 때 조성된 졸정원(拙政園)과 같은 강남 정원 문화는 송대 산수화로부터 기인했다. 산수에서 등장하는 산속의 작은 정자나 가옥들이 정원에 옮겨진 것이다. 이는 곽희가 "임천고치"에서 말한 "가볼 수 있고, 바라볼 수 있을 뿐만 아니라, 노닐 수 있고, 살 수 있는 곳"을 화폭 속에 그려야 한다는 것이 명 청대에 이르러서는 현실로 옮겨진 것이다. 또한 현대에 있어서는 환경디자인에 이르기까지 그 영향을 미친다고 할 수 있다. 이와 관련된 지속적인 연구는 앞으로 가상현실, 증강현실 등 디자인 발전 연구, 더 나아가 문화산업의 기초자료로서 복합학문, 학제간 교류에 있어서 없어서는 안 될 중요한 기초자료가 될 것이다.