• Title/Summary/Keyword: high-availability

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Inhibitory Effects of Sargassum thunbergii Ethanol Extract against α-amylase (지충이 에탄올 추출물의 α-amylase 저해활성)

  • Lee, So-Jeong;Song, Eu-Jin;Kim, Koth-Bong-Woo-Ri;Lee, Chung-Jo;Jung, Ji-Yeon;Kwak, Ji-Hee;Choi, Moon-Kyoung;Kim, Min-Ji;Kim, Tae-Wan;Ahn, Dong-Hyun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.6
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    • pp.648-653
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    • 2010
  • This study was performed to investigate the inhibitory activity of Sargassum thunbergii (ST) against ${\alpha}$-amylase and elucidate the availability of ST extract as a functional food agent. To test the inhibitory activity of ST against ${\alpha}$-amylase, porcine pancreatic ${\alpha}$-amylase and potato starch were used as substrates. It was revealed that ST crude ethanol extracts have high ${\alpha}$-amylase inhibitory activity. Subsequently, ST crude ethanol extract was separated into five partition layers by solvent extraction: n-hexane, chloroform, ethyl acetate, butanol, and water. Chloroform and n-hexane fractions showed higher inhibitory activities than did acarbose (positive control). To confirm the changes in enzyme inhibitory activity by physical treatments, ST crude ethanol extract was subjected to heat, pH, and ${\gamma}$-irradiation treatments. In all heat treatments with the exception of one ($121^{\circ}C$, 15 min), the inhibitory activity was increased compared with the untreated group. With regard to pH stability, ST extract showed no significant changes at pH 4.6, but somewhat decreased inhibitory activity was revealed at pH 2, 8, and 10. On the other hand, ST ethanol extract was stable under ${\gamma}$-irradiation under all conditions (3.20 kGy). In summary, ST ethanol extract can be used in the food industry as a natural ${\alpha}$-amylase inhibitor.

Iron Intake During Pregnancy on Serum Concentrations of Trace Minerals in Mothers and Neonates (임신기간 중 철 섭취가 모체와 제대 혈청의 미량 무기질 농도에 미치는 영향)

  • Kim, Hye-Ra;Lim, Hyeon-Sook
    • Journal of Nutrition and Health
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    • v.41 no.3
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    • pp.242-253
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    • 2008
  • It is a common clinical practice to recommend taking iron supplements for pregnant women during gestation. Although it is required to ensure adequate iron stores during pregnancy, there has been some debate over the interference effects of excessive iron load, because it is possible to compete in the transport in the intestine and placenta and in binding to serum proteins of other trace minerals. In this study, maternal and neonatal serum concentrations of Fe, Zn, Cu, Se, Cr, Mn, and Co were assessed along with maternal Fe intakes. A total of 124 pregnant women and their term neonates participated voluntarily in this research. The women were divided into one of the three groups {high Fe intake (HFI), median Fe intake (MFI), and low Fe intake (LFI)} by their total Fe intakes and one of the two groups (Anemic and Normal) by their Fe nutritional status. All the data were compared among the three groups and between the two groups also. Total Fe intakes of HFI, MFI, and LFI groups were 140.8 ${\pm}$ 76.1, 68.0 ${\pm}$ 11.2, and 30.2 ${\pm}$ 8.6 mg/day, respectively. Those of Anemic and Normal groups were 90.1 ${\pm}$ 74.8 and 86.6 ${\pm}$ 46.8 mg/day, respectively. Maternal Hb concentration and Hct were not significantly different among HFI, MFI, and LFI groups but those were significantly different between Anemic and Normal groups. However, neonatal Hb concentration was not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups either. Maternal serum Fe concentrations of the three groups, HFI, MFI, and LFI, were similar but that of Anemic group was significantly lower compared to Normal group. However, there was no significant difference in neonatal serum Fe concentrations among the three groups and between the two groups either. Serum concentrations of the other trace minerals in both mothers and neonates were not significantly different among HFI, MFI, and LFI groups and between Anemic and Normal groups. In addition, in the maternal serum, Fe concentration was positively correlated to Zn and Se concentration, respectively. As for the neonatal serum, Fe concentration showed a positive correlation to Zn, Cu, Mn, Se, and Co concentration, respectively. No trace mineral concentration was found to correlate negatively to Fe concentration in both maternal and neonatal serum, The results in this study indicate that Fe intakes of pregnant women, even if it is considerably above the level of estimated average requirement (EAR), may not affect serum Fe concentration in both mothers and neonates. In addition it might not influence adversely on the availability of other trace minerals including Zn and Cu in both mothers and neonates.

Nutritional Values of Rice Bran and Effects of Its Dietary Supplementations on the Performances of Broiler Chickens (생미강의 영양적 가치와 사료 내 첨가가 육계 성적에 미치는 영향)

  • Shin Y. K.;Kim K. E.;Shin S. C.;You S. J.;Kim S. K.;An B. K.;Kang C. W.
    • Korean Journal of Poultry Science
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    • v.31 no.3
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    • pp.145-150
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    • 2004
  • Two experiments were conducted to evaluate the nutritional values of rice bran and to examine effects of its dietary supplementation on broiler performances. In the first experiment, true metabolizable energy(TME), nitrogen corrected true metabolizable energy(TMEn), and true amino acid availability(TAAA) values of the rice bran were determined by force-feeding sixteen roosters(ISA-Brown). In the second experiment, 3-week-old male broiler chickens(Avian) were divided into four groups and fed each one of four experimental diets containing 0, 5, 10 or 15% rice bran for 21 days. TME and TMEn values of the rice bran(dry matter basis) were 3.25 kcal/g and 3.12 kcal/g, respectively, and the average TAAA value of the 16 amino acids was 76.21%. The average feed intake and body weight gain of the birds fed diets containing rice bran were apparently greater than those of the control group although the differences were not significant statistically. From the results, it can be concluded that feed formulation using bioavailability values, such as TMEn and TAAA, is an effective method for protecting the high variation in growth performances and that rice bran can be used for broiler feeds to 15% without any significant negative effects.

Recent patterns of Enterobius uermiculuris infection in some school children, Korea (국내 일부 지역 학동에 있어서 요충의 최근 감염상)

  • 양용석
    • Parasites, Hosts and Diseases
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    • v.26 no.3
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    • pp.215-220
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    • 1988
  • To investigate the infection status of Enterobius vermicularis the author tried surveys by srotchtape anal swab on school-children and household environmental factors considered to have inauences on the infection were analysed by an inquiry method with questionnaire. The survey was carried out in October, 1986 and 1988 in urban and suburban areas and the results could be summarized as follows: 1. The egg Positive rate in anal swab. was 16.0% (male 14.5%, female 17.6%) out of 2, 156 school-children and higher in female group. 2. The egg Positive rate of suburban school-children (175% out of 1, 305 children of two primary schools) was a little higher than that of urban school.children (13.6% out of 851 children of one primary school). 3. The questionnaire analysis on environmental factors showed some significant relations between the egg Positive rate and such factors as the number of brothers and sisters, householder's occupation, and availability of childroom or bathroom. The results indicate that, although enterobiasis in school-children has shown decreasing tendency in Korea, it is still considerably high in some urban and suburban areas.

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Clinical Availability of Rapid Strep Test in Children with Group A Streptococcal Pharyngotonsilitis (A군 연쇄구균 상기도 감염에 있어 신속검사의 유용성)

  • Kim, Yeon Ho;Bae, Young Min;Cha, Sung Ho;Ma, Sang Hyuk
    • Pediatric Infection and Vaccine
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    • v.8 no.1
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    • pp.90-93
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    • 2001
  • Purpose : The accurate diagnosis and proper treatment of group A streptococal infection should be emphasized concerning about possible development of late sequelae, such as acute rheumatic fever and acute glomerulonephritis. Inadequate & improperance of antobiotics have resulted in increased number of antibiotic-resistant bacteria. We would like to know the clinical usefulness of rapid strep test compared with conventional throat culture in out-patients with acute pharyngotonsilitis. Methods : From Sep. 2000. to Jan. 2001, rapid strep test(LINK 2 Strep A, USA) & throat culture were taken from 87 patients with clinically suspect pharyngotonsilitis from Masan Fatima hospital & kyunghee university hospital. Results : Of 87 cases with pharyngitis, 39 cases proved to have group A streptococci by throat culture. The positive predictive value of rapid test was 92.3%(36 of 39 cases) and sensitivity test was 81.8%(36 of 44 cases). The specificity of rapid test was 93.0%(40 of 43 cases) and negative predictive value was 83.3%(40 of 48 cases). Conclusion : The positive predictive value & specificity of rapid strep test is high. And so, this test will give the pediatricians practical guidance of antibiotic use in patients with pharyngitis. But more efforts should be made to prevent antibiotics abuse and correct diagnosis of pharyngitis.

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Effect of Allium Victorialis Var. platyphyllum Leaves on Triton WR-1339-Induced and Poloxamer-407-Induced Hyperlipidemic Rats and on Diet-Induced Obesity Rats (식이성 고지혈 및 비만에 대한 산마늘 추출물의 효과)

  • Choi, Jong-Won;Lee, Kyung-Tae;Kim, Won-Bae;Park, Kwang-Kyun;Chung, Won-Yun;Lee, Jin-Ha;Lim, Sang-Cheol;Jung, Hyun-Ju;Park, Hee-Juhn
    • Korean Journal of Pharmacognosy
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    • v.36 no.2 s.141
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    • pp.109-115
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    • 2005
  • The herb of Allium victorialis var. platyphyllum (Liliaceae) has been used as an edible wild herb and to treat heart failure and gastritis. We have already reported antihyperlipidemic anti-tumor effects of this plant. To enlarge the commercial availability of this food, it was investigated whether the extracts of A. victorialis var. platyphyllum reduce hyperlipidemia and obesity or not. The plants tested in this experiment were collected from two eco-types of Is. Ullung and Mt. Odae cultivated at Pyongchang. Extracts were prepared by extracting the fresh leaves and those dried at $36^{\circ}C$ and $90^{\circ}C$, respectively. Pretreatment with the ethanolic extracts for two weeks(p.o.) reduced serum triglyceride-, total cholesterol- and LDL-cholesterol contents in rats induced by Triton WR-1339, respectively. Furthermore, oral administration of the extracts also inhibited the hyperlipidemia induced with oral diet of 30% corn oil. In the other attempt to find to alleviate the obesity, the model rats with obesity were induced by the high fat-diet for six weeks. Post-treatment with the extracts for two weeks significantly reduced the hyperlipidemia. Retroperitoneal-, epidymal- and total abdominal fat pad weights were considerably reduced at 100 mg/kg oral administration of the extracts. Increased feces lipid contents were also found in the rat treated with the extracts. The extract may lead to the higher activity in treatment of hyperlipidemia and obesity than of the dried one.

Calculation and Applicability of Rotifers Biomass (Polyarthra spp.) based on Length-Weight Relationship and Spatial Distribution of Body Length (윤충류 생체량 계산과 적용에 관한 고찰 및 제언: Polyarthra의 체장 분포를 이용한 길이-무게 관계식 및 생체량 비교 분석)

  • Oh, Hye-Ji;Seo, Dong-Hwan;Choi, Moonjung;Jeong, Hyun-Gi;Kim, Hyun-Woo;Oh, Jong Min;Chang, Kwang-Hyeon
    • Korean Journal of Ecology and Environment
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    • v.51 no.3
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    • pp.205-211
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    • 2018
  • In this study, we estimated the applicability of length-weight relationship-based biomass calculations by comparison of body length of genus Polyarthra collected from different habitats. Through the comparison, we also tested availability of representative species-specific biomass value of Polyarthra which is often used without length measurement. Polyarthra samples were collected from rivers (Han River and Nakdong River) and reservoir (Paldang Reservoir), and the body length was measured for statistical comparison among habitats and biomass calculations using different equations suggested previously. According to the results, the body length of Polyarthra spp. was significantly different among sampling sites, and the necessity of body length measurement for rotifer species in each situation has been suggested rather than using the representative biomass values which is fixed without considering time and space. Comparison of suggested biomass calculations based on our measured Polyarthra body length, the equation suggested by McCauley showed more reasonable range of biomass values than that suggested by EPA. In addition, in order to calculate more accurate biomass, it is necessary to measure the body length of rotifers, at least more than 44 individuals to reduce error probability to less than 5% with 99% probability. However, since direct measurement of rotifers biomass is limited, it is considered that further analyses are required for more precise application of rotifer biomass of which has high variability due to complex morphologies and species-specific cyclomorphosis often induced by biotic and abiotic factors in the habitats.

A Study on the Practical Application of Image Control Point Using Stereo Image Chip (입체 영상칩을 이용한 영상기준점 활용방안에 관한 연구)

  • Kim, Hoon-Jung;Kim, Kam-Lae;Cheong, Hae-Jin;Cho, Won-Woo
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.26 no.4
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    • pp.423-431
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    • 2008
  • The control surveying which aims at identifying the coordinate system of satellite images with that of ground is a repeatedly performed essential process to produce digital ortho - photos and it acts as the main factor to increase the production cost of the photos by duplicated budgets and redundant works when executing the projects for acquiring basic geographical information from high density satellite images. During the experimentation, an application system was established for producing a stereo image chip by the analysis of DPPDB file structure, the stereo image chip was produced with SPOT and IKONOS images, the analysis of 3D modeling accuracy was performed to secure the required accuracy and to present the optimal number and deployment of the control points, and a 3D modeling was performed for new SPOT images and lastly, 3D ground coordinates were extracted by the observation of the same points through the overlapping with the new images. As the results of the research, it is proved that the stereo image chip can be used as the ground controls through the accuracy analysis between the coordinates of the images and the ground, close results were obtained between the coordinates by the ground survey and those by the 3D modeling using new images and the observation of the same points, positional changes were not found during observing the same points, and the research presented the methodology for improving the process of the control survey by showing the availability of the image controls on the stereo image chip instead of the ground controls.

Software Development for Dynamic Positron Emission Tomography : Dynamic Image Analysis (DIA) Tool (동적 양전자방출단층 영상 분석을 위한 소프트웨어 개발: DIA Tool)

  • Pyeon, Do-Yeong;Kim, Jung-Su;Jung, Young-Jin
    • Journal of radiological science and technology
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    • v.39 no.3
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    • pp.369-376
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    • 2016
  • Positron Emission Tomography(PET) is nuclear medical tests which is a combination of several compounds with a radioactive isotope that can be injected into body to quantitatively measure the metabolic rate (in the body). Especially, Phenomena that increase (sing) glucose metabolism in cancer tissue using the $^{18}F$-FDG (Fluorodeoxyglucose) is utilized widely in cancer diagnosis. And then, Numerous studies have been reported that incidence seems high availability even in the modern diagnosis of dementia and Parkinson's (disease) in brain disease. When using a dynamic PET iamge including the time information in the static information that is provided for the diagnosis many can increase the accuracy of diagnosis. For this reason, clinical researchers getting great attention but, it is the lack of tools to conduct research. And, it interfered complex mathematical algorithm and programming skills for activation of research. In this study, in order to easy to use and enable research dPET, we developed the software based graphic user interface(GUI). In the future, by many clinical researcher using DIA-Tool is expected to be of great help to dPET research.

Texture Feature Analysis Using a Brain Hemorrhage Patient CT Images (전산화단층촬영 영상을 이용한 뇌출혈 질감특징분석)

  • Park, Hyonghu;Park, Jikoon;Choi, Ilhong;Kang, Sangsik;Noh, Sicheol;Jung, Bongjae
    • Journal of the Korean Society of Radiology
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    • v.9 no.6
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    • pp.369-374
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    • 2015
  • In this study we proposed a texture feature analysis algorithm that distinguishes between a normal image and a diseased image using CT images of some brain hemorrhage patients, and generates both Eigen images and test images which can be applied to the proposed computer aided diagnosis system in order to perform a quantitative analysis for 6 parameters. And through the analysis, we derived and evaluated the recognition rate of CT images of brain hemorrhage. As the results of examining over 40 example CT images of brain hemorrhage, the recognition rates representing a specific texture feature-value are as follows: some appeared to be as high as 100% including average gray level, average contrast, smoothness, and Skewness while others showed a little low disease recognition rate: 95% for uniformity and 87.5% for entropy. Consequently, based on this research result, if a software that enables a computer aided diagnosis system for medical images is developed, it will lead to the availability for the automatic detection of a diseased spot in CT images of brain hemorrhage and quantitative analysis. And they can be used as computer aided diagnosis data, resulting in the increased accuracy and the shortened time in the stage of final reading.