• Title/Summary/Keyword: high pressure homogenation

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Novel Encapsulation with New Glyceryl Ester Vesicle Enhances Stability of Nanoemulsion Containing Astaxanthin (아스타잔틴을 포함하는 나노에멀젼의 안정성 향상을 위한 신규 Glyceryl Ester 이용 캡슐화)

  • Kim, Dong Myung;Hong, Weon Ki;Kong, Soo Sung;Lee, Un Yep
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.3
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    • pp.225-231
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    • 2013
  • Oil in water nanoemulsion of astaxanthin was prepared by high pressure homogenization. The emulsifying conditions including emulsifier type, concentration and astaxanthin concentration were optimized. Stability of nanoemulsion was measured using zetasizer, freeze-fracture scanning electron microscope (FF-SEM), particle analyzer and colorimeter. The mean diameter of the dispersed particles containing astaxanthin ranged from 160 to 190 nm. Size distribution was unimodal and extended from 40 to 200 nm. The nanoemulsion prepared by glyceryl citrate/lactate/linoleate/oleate had smaller particle size and narrow size distribution. Stable incorporation of astaxanthin in nanoemulsion was performed and checked using high performance liquid chromatography (HPLC), freeze-fracture scanning electron microscope (FF-SEM). Physical stability of nanoemulsion was not significantly changed during storage at both light and thermal condition for a month with zeta potential value of -41 mV meaning stable colloid.