• Title/Summary/Keyword: high platform base

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Recent Development of Protein Microarray and Proteogen Platform

  • Han, Moon-Hi;Kang, In-Cheol;Lee, Yoon-Suk;Cho, Yong-Wan;Lee, Eun-Kyoung
    • 한국생물공학회:학술대회논문집
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    • 2005.04a
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    • pp.47-47
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    • 2005
  • There are many different surface technologies currently applied for preparation of protein chips. However, it requires innovative surface chemistry for capture proteins to be immobilized on chip surface keeping their conformation and activity intact and their orientation right, while they bind tightly and densely in a given array spot. Proteogen has developed 'ProteoChip BP' coated with novel proprietary linker molecules $(ProLinker^{TM})$ for efficient and robust immobilizations of capture proteins by improving surface properties of molecular captures. It was demonstrated that $ProLinker^{TM}$ gave the best surface performance in preparation of protein microarray chip base plates among others currently available on the market. In particular, the $ProLinker^{TM}-based$ surface chemistry has demonstrated to provide excellent performance in preparation of 'Antibody Chip' for analysis of biomarkers as well as proteome expression profiles. The linker molecule has also shown to be well applicable for development of biosensors and micro-beads as well as protein microarray and nano-array. ProteoChip BP can be used either for preparation of high-density array by using a microarrayer or for preparation of 'Well-on-a-Chip' with low density array, which is better applicable for quantitative analysis of biomarkers or protein-protein interactions. The biomarker assay can be performed either by direct or sandwich methods of fluorescence immunoassay. Application of ProteoChip BP has been well demonstrated by the extensive studies of 1) tumor-marker assays, 2) new drug screening by using 'Integrin Chip' and 3) protein expression profile analysis. Some of experimental results will be presented.

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Serious Game Design for the Elderly using Arcade Game Machines (아케이드 게임기기를 활용한 실버용 기능성게임 디자인)

  • Kim, Sung-Jin;Kim, Mi-Jin
    • The Journal of the Korea Contents Association
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    • v.9 no.7
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    • pp.9-18
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    • 2009
  • This paper deals with the elderly serious game design which makes full use of the existing arcade game machine. This serious game is on the issue for its positive role recently. Serious arcade game for the elderly which is made up arcade platform-based combined contents manufacture technology has an element which is having a fun for building up physical and mental health. It also has a special objective which can prevent against senile dementia. Above-mentioned serious arcade game which has a special objective in both hardware part and software part is needed to study how to design. Accordingly, this paper presents how to make up special-purpose entertainment machine and contents development by biologic, social, and psychological researches and data about the elderly - main users. We hope that this paper can be used as a base for expansion of new industrial field by integrating new product development for the elderly with high game technology.With the help of information technology

A study on the Development Direction of Unmanned Systems for Subterranean Operations for the Special Operations Teams (특수작전팀의 지하작전용 무인체계 발전방향 연구)

  • Sang-Keun Cho;Jong-Hoon Kim;Sung-Jun Park;Bum-June Kwon;Ga-Ram Jeong;Sang-Hyuk Park
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.2
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    • pp.307-312
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    • 2023
  • North Korea has already been using underground space for military purposes for decades, and is currently developing it as a key base for operating asymmetric forces. Accordingly, the special operations teams need fighting methods, weapon systems, and organizational structures to carry out subterranean operations. This paper presents an unmanned system platform for subterranean operations that combines tilt-rotor type drones, high-tech sensors, communication repeaters, and small robots, and a system that can be operated by special operation teams. Based on this, the survivability of the special operations teams can be strengthened and operational utility can be maximized. Afterwards, if Special Warfare Command collects collective intelligence based on the ideas related to subterranean operations presented in this paper and further develops these, it will be possible to drive subterranean operations doctrines, weapon systems, and organizational structures optimized for the battlefield on the Korean Theater of Operations in the near future.

Analysis on the Effects of Interference from HAPS Ground Stations to P-MP FWA System (HAPS 지상국에서 P-MP FWA 시스템으로의 간섭 영향 분석)

  • Ham Hyung-Il;Kang Young-Heung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.2 s.105
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    • pp.152-157
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    • 2006
  • In this paper, we have analyzed the effects of interference from HAPS ground stations to P-MP FWA base station and to P-MP FWA terminal station using more detail parameters such as a new interference model, a realistic HAPS scenario, practical antenna patterns for both the HAPS system and FWA systems. The analysis results show that, in the case of interference from HAPS GSs into a P-MP BS, compatibility of the two systems can be obtained by using a sectored BS antenna with the boresight directed away from the nadir. However, in the case of interference from HAPS GSs into a P-MP TS, the two systems cannot operate effectively in the same band unless the separation distance is guranteed and/or some form of interference mitigation technique is employed such as dynamic channel allocation.

Extending the OPRCB Seismic isolation system's governing equations of motion to 3D state and its application in multi-story buildings

  • M. Hosseini;S. Azhari;R. Shafie Panah
    • Earthquakes and Structures
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    • v.24 no.3
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    • pp.217-235
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    • 2023
  • Orthogonal pairs of rollers on concave beds (OPRCB) are a low-cost, low-tech rolling-based isolating system, whose high efficiency has been shown in a previous study. However, seismic performance of OPRCB isolators has only been studied in the two-dimensional (2D) state so far. This is while their performance in the three-dimensional (3D) state differs from that of the 2D state, mainly since the vertical accelerations due to rollers' motion in their beds, simultaneously in two orthogonal horizontal directions, are added up and resulting in bigger vertical inertia forces and higher rolling resistance. In this study, first, Lagrange equations were used to derive the governing equations of motion of the OPRCB-isolated buildings in 3D. Then, some regular shear-type OPRCB-isolated buildings were considered subjected to three-component excitations of far- and near-source earthquakes, and their responses were compared to those of their fixed-base counterparts. Finally, the effects of more realistic modeling and analysis were examined by comparing the responses of isolated buildings in 2D and 3D states. Response histories were obtained by the fourth-order Runge-Kutta-Nystrom method, considering the geometrical nonlinearity of isolators. Results reveal that utilizing the OPRCB isolators effectively reduces the acceleration response, however, depending on the system specifications and earthquake characteristics, the maximum responses of isolated buildings in the 3D state can be up to 40% higher than those in the 2D state.

An analysis on Regional Economic Impact of Chungnam Following R&D Investment -Focused on Metal Industry- (R&D 투자에 따른 충남지역 경제효과 분석 -금속산업을 중심으로-)

  • Chung, Young-Keun;Lim, Eungsoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.72-76
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    • 2020
  • The central government operates a Balanced National Development Special Account, and wants more regional development. Many local governments try various ways to establish a foothold for independent governments. Establishing a regional base center is one of the major plans for economic development, and Chungnam is proceeding with "establishing a platform for Chungnam high-tech metal materials." This paper analyzes the effects on the regional economy based on the expense that goes into a regional base center in Chungnam. For the analysis, an input/output table is used, and we present the effects of the annual input cost in detail. This study specifically analyzes the production-inducing effects, the value-added inducing effects, and employment-inducing effects using a demand-drive model. Furthermore, we suggest the effectiveness of this same business. The analyzed results give 32,230,000,000 in production-inducing effects, 13,820,000,000 in value-added inducing effects, and 101 in employment-inducing effects. These results can be used as reasonable evidence to promote the project, since the production-inducing effects and value-added inducing effects show high results, compared to input. The employment-inducing effects can also be used to create new jobs and figure out the number of people employed through this project.

Enhanced Primary Production in Response to Freshwater Inflow in the Nakdong River Estuary: Characteristics of land-Ocean Coupling (LOC) (낙동강 하구에서 담수 유입에 따른 연안 클로로필-a 증가 : 낙동강의 육상-해양 coupling 패턴 분석)

  • KIM, SUHYUN;AN, SOONMO
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.26 no.2
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    • pp.96-109
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    • 2021
  • Since terrestrial input plays a major role in coastal primary production, an understanding of land-ocean coupling (LOC) is key to understand coastal ecological changes. In this study, the LOC has been classified into three stages (i.e., the baseflow, plume event and residual flow). In order to characterize its pattern in Nakdong River estuary, multi-platform data were obtained from remote sensing (geostationary ocean color image (GOCI)), in-situ measurement (marine environment information system (MEIS)), on-site measurement (discharge data and meteorological data). The MEIS data were grouped into three stages of LOC using principal component analysis (PCA), and the LOC (2013 ~ 2018) was examined at each stage using multi-platform data. In the Nakdong River estuary, the maximum value of chlorophyll-a (chl-a) was unexpectedly appeared during the plume event. It is assumed that there was no significant increase in turbidity, expected during the typical plume event, together with the weak flushing effect, caused the enhanced phytoplankton growth. Compared with other estuaries, LOC is common in estuaries affected by freshwater inflow, but LOC has different pattern depending on the size of the plume. While estuaries that form small plumes of about 10 km (low freshwater discharge and weak flushing effect) observed high chl-a in the plume event because the phytoplankton can response to the increased nutrient more rapidly. estuaries that form large plumes of more than 100 km est (high freshwater discharge and strong flushing effect) follow the typical LOC pattern conceptualized in this study (high chl-a in the residual flow).

Novel construction of quasi-cyclic low-density parity-check codes with variable code rates for cloud data storage systems

  • Vairaperumal Bhuvaneshwari;Chandrapragasam Tharini
    • ETRI Journal
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    • v.45 no.3
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    • pp.404-417
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    • 2023
  • This paper proposed a novel method for constructing quasi-cyclic low-density parity-check (QC-LDPC) codes of medium to high code rates that can be applied in cloud data storage systems, requiring better error correction capabilities. The novelty of this method lies in the construction of sparse base matrices, using a girth greater than 4 that can then be expanded with a lift factor to produce high code rate QC-LDPC codes. Investigations revealed that the proposed large-sized QC-LDPC codes with high code rates displayed low encoding complexities and provided a low bit error rate (BER) of 10-10 at 3.5 dB Eb/N0 than conventional LDPC codes, which showed a BER of 10-7 at 3 dB Eb/N0. Subsequently, implementation of the proposed QC-LDPC code in a softwaredefined radio, using the NI USRP 2920 hardware platform, was conducted. As a result, a BER of 10-6 at 4.2 dB Eb/N0 was achieved. Then, the performance of the proposed codes based on their encoding-decoding speeds and storage overhead was investigated when applied to a cloud data storage (GCP). Our results revealed that the proposed codes required much less time for encoding and decoding (of data files having a 10 MB size) and produced less storage overhead than the conventional LDPC and Reed-Solomon codes.

Preparation of Nanocolumnar In2O3 Thin Films for Highly Sensitive Acetone Gas Sensor

  • Han, Soo Deok;Song, Young Geun;Shim, Young-Seok;Lee, Hae Ryong;Yoon, Seok-Jin;Kang, Chong-Yun
    • Journal of Sensor Science and Technology
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    • v.25 no.6
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    • pp.383-387
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    • 2016
  • Well-ordered nanocolumnar indium oxide ($In_2O_3$) thin films have been successfully fabricated by glancing angle deposition (GAD) using an e-beam evaporator. Nanocolumnar structures have a porous and large surface area with a narrow neck between nanocolumns, which allows them to detect minute amounts of gases. The nanocolumnar $In_2O_3$ thin films were fabricated by the GAD process at five different positions, viz. top, bottom, center, left, and right in a four inch substrate holder. There was a divergence in the thickness and the base resistance of each sensor. However, all the sensors exhibited extremely high sensitivity that was greater than $10^3$ times the change in electrical resistance after being exposed to 50 ppm of acetone gas at $300^{\circ}C$. Furthermore, the nanocolumnar $In_2O_3$ sensors displayed an extremely low detection limit (1.2 ppb) in dry atmosphere as well as in high humidity (80%). We demonstrated that the GAD nanocolumnar $In_2O_3$ sensors have an enormous potential for many applications owing to their particularly simple and reliable fabrication process.

Application and Policy Direction of Blockchain in Logistics and Distribution Industry (물류 및 유통산업의 블록체인 활용과 정책 방향)

  • Kim, Ki-Heung;Shim, Jae-Hyun
    • The Journal of Industrial Distribution & Business
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    • v.9 no.6
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    • pp.77-85
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    • 2018
  • Purpose - The purpose of this study is to subdivide trade transaction-centered structure in a logistics/distribution industry system to apply blockchain, to establish and resolve with which types of technology, and to provide policy direction of government institution and technology to apply blockchain in this kind of industry. Research design, data, and methodology - This study was conducted with previous researches centered on cases applied in various industry sectors on the basis of blockchain technology. Results - General fields of blockchain application include digital contents distribution, IoT platform, e-Commerce, real-estate transaction, decentralized app. development(storage), certification service, smart contract, P2P network infrastructure, publication/storage of public documents, smart voting, money exchange, payment/settlement, banking security platform, actual asset storage, stock transaction and crowd funding. Blockchain is being applied in various fields home and abroad and its application cases can be explained in the banking industry, public sector, e-Commerce, medical industry, distribution and supply chain management, copyright protection. As examined in the blockchain application cases, it is expected to establish blockchain that can secure safety through distributed ledger in trade transaction because blockchain is established and applied in various sectors of industries home and abroad. Parties concerned of trade transaction can secure visibility even in interrupted specific section when they provide it as a base for distributed ledger application in trade and establish trade transaction model by applying blockchain. In case of interrupted specific section by using distributed ledger, blockchain model of trade transaction needs to be formed to make it possible for parties concerned involved in trade transaction to secure visibility and real-time tracking. Additionally, management should be possible from the time of contract until payment, freight transfer to buyers through land, air and maritime transportation. Conclusions - In order to boost blockchain-based logistics/distribution industry, the government, institutionally, needs to back up adding legal plan of shipping, logistics and distribution, reviewing standardization of electronic switching system and coming up with blockchain-based industrial road maps. In addition, the government, technologically, has to support R&D for integration with other high technology, standardization of distribution industry's blockchain technology and manpower training to expand technology development.