• Journal of Preventive Medicine and Public Health
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• v.38 no.2
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• pp.175-181
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• 2005

Objectives: This study estimated the burden of disease due to high alcohol consumption using DALY, a composite indicator recently developed by the Global Burden of Disease study group. The results were analyzed by age and sex. Methods: Firstly, high alcohol consumption-related diseases, and their relative risk (RR), were selected. Secondly, population attributable fractions (PAFs) were computed using formulae, including the relative risk (RR) and prevalence of exposure (Pe). Thirdly, the DALYs of high alcohol consumption-related diseases were estimated. Lastly, the attributable burdens of diseases due to high alcohol consumption wereconcluded as being the sum of the products that multiplied the DALYs of high alcohol consumption-related diseases by their population attributable fraction (PAF). Results : The burden of high alcohol consumption in Korea was 2992.3 person years (PYs) per 100,000 persons in men, and 1426.6 in women. For men, the high alcohol consumption-induced diseases with the five biggest burdens were liver cirrhosis, hypertensive disease, liver cancer, cerebral infarction and intracerebral hemorrhage. For women, these were cerebral infarction, intracerebral hemorrhage, hypertensive disease, liver cirrhosis and liver cancer. Conclusion: This study highlighted the attributable fraction of diseases due to exposure to high alcohol consumption, by quantifying the results of exposure to risk factors. Therefore, it is now possible to assess interventions for risk factors in quantifiable terms in each population. Finally, measuring the risk factor burdens was expected to contribute to priority setting and effective resource allocation in public health policy.

• Preventive Nutrition and Food Science
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• v.9 no.1
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• pp.34-38
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• 2004

High-pungency red pepper and capsaicin modulate circulating hormone levels and induce lipolysis in adipose tissue in vivo. This study was designed to investigate the lipolytic activity of adipocytes by high-pungency red pepper extract in vitro. High-pungency red pepper (var. Chungyang) powder showed 126.1 mg% of capsaicinoid which was 3 x higher than low-pungency red pepper powder (var. Daemyung). To study the effects of high-pungency red pepper extract on lipolytic activity, preadipocytes were separated from the epidermal fat of 14 day-old rats, induced to differentiate into adipocytes and were treated with red pepper extracts. The amount of glycerol released from adipocytes into the culture medium was analysed to measure lipolytic activity. Glycerol release from adipocytes was increased in a dose-dependent manner with high-pungency red pepper extract treatment. However, there was no significant change in the glycerol release when adipocytes were treated with low-pungency red pepper extract. To investigate whether lipolysis by high-pungency red pepper extract is caused by capsaicin, glycerol release was detected after the treatment of adipocytes with capsaicin. Glycerol release was significantly increased by capsaicin. These results suggest that high-pungency red pepper extract might have a direct lipolytic activity in adipocytes that is mediated by capsaicin.

• Journal of Microbiology and Biotechnology
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• v.14 no.4
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• pp.796-804
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• 2004

We found previously that dietary high fat caused obesity, and levan supplementation to the regular diet reduced adiposity and serum lipids. In the present study, we examined the effects of levan [high-molecular-mass $\beta$-(2,6)-linked fructose polymer] supplement on the development of obesity and lipid metabolism in rats fed with high-fat diet. Thus, to determine whether the dietary levan may have the anti-obesity and hypolipidemic effects, 4-wk-old Sprague Dawley male rats were fed with high-fat diet for 6 wk to induce obesity, and subsequently fed with 0, 1, 5, or 10% levan supplemented high-fat diets (w/w) for another 4 wk. For the comparison, a normal control group was fed with AIN-76A diet. Supplementation with levan resulted in a significant reduction of high-fat-induced body weight gain, white fat (i.e., epididymal, visceral, and peritoneal fat) development, adipocyte hypertrophy, and the development of hyperinsulinemia and hyperlipidemia in a dose-dependent manner. Serum triglyceride and free fatty acid levels were greatly reduced by levan supplementation. Serum total cholesterol level was reduced, whereas the HDL cholesterol level was increased by dietary levan. The expression of uncoupling protein (UCP) was increased by dietary high fat, and was further induced by levan supplementation. The mRNA level of UCP1, 2, and 3 in brown adipose tissue (BAT) and UCP3 in skeletal muscle was upregulated in rats fed with dietary levan. In conclusion, upregulated UCP mRNA expression may contribute to suppression of development of obesity through increased energy expenditure. The present results suggest that levan supplementation to the diet is beneficial in suppressing diet-induced obesity and hyperlipidemia.

• Korean Journal of Acupuncture
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• v.26 no.2
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• pp.61-74
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• 2009

Objectives: The warm needling technique is a method which combines the effects of acupuncture with those of moxibustion. The purpose of this study was to find the stimulus effects of a high frequency warm needling device when stimulating acupoint $LI_4$ on the carrageenan-induced arthritis. Methods: This study was to observe the effects to edema reaction, WBF(weight bearing force), NO concentration, nNOS expression after the electro high frequency stimulus of high frequency warm needling device on LI4 with insulated acupuncture needle. Results: The effect of the high frequency warm needling device is to rise up the temperature in proportion to the current intensity. After stimulating on the acupoint $LI_4$ of the carrageenan-induced arthritis in rats with the high frequency warm needling device, it significantly reduced edema in the rat's foot. In addition, WBF, NO concentration of spinal cord (nmol/mg), and nNOS relative expression were reduced. Conclusions: The above results support the idea that stimulus by the high frequency warm needling device on $LI_4$ produces a potent analgesic effect in the arthritis pain model of the rat. Moreover, stimulus by the high frequency warm needling device modulates endogenous NO through the suppression of nNOS protein expression.

• Journal of Electrical Engineering and Technology
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• v.11 no.1
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• pp.125-134
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• 2016

We propose an efficient high voltage level shifter for a high side Buck converter driving a light-emitting diode (LED) lamp. The proposed circuit is comprised of a low voltage pulse width modulation (PWM) signal driver, a coupling capacitor, a resistor, and a diode. The proposed method uses a property of a PWM signal. The property is that the signal repeatedly transits between a low and high level at a certain frequency. A low voltage PWM signal is boosted to a high voltage PWM signal through a coupling capacitor using the property of the PWM signal, and the boosted high voltage PWM signal drives a p-channel metal oxide semiconductor (PMOS) transistor on the high side Buck converter. Experimental results show that the proposed level shifter boosts a low voltage (0 to 20 V) PWM signal at 125 kHz to a high voltage (370 to 380 V) PWM signal with a duty ratio of up to 0.9941.

• Journal of the Korean Society of Safety
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• v.35 no.4
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• pp.9-14
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• 2020

It is necessary to apply a non-contact high-speed scanning system that can measure in real time in order to prevent the dropping and deformation of the main parts of railway vehicles during high-speed running. Recently, research on a scanning system that detects the deformation state of main parts from a video image taken using a high-performance camera has been actively pursued. In this study, we researched an analysis algorithm of a high-speed scanning system that uses a high-performance camera to monitor the deformation and drop-out state of the main components of the running units equipment in real time.

• 한국연소학회:학술대회논문집
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• 2012.11a
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• pp.101-103
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• 2012

Characteristic of aluminum ignition under high temperature and high pressure is studied using lasers. The laser ablation method is used to generate aluminum particles exposed to a high pressure by using a nanosecond pulsed laser where the range of ablation pressure varies between 0.35 and 2.2 GPa. A $CO_2$ laser is used to supply radiative heat to the aluminum target surface for providing high temperature ranging between 5000~9300 Kelvin. The ignition is confirmed using spectroscopy analysis of AlO vibronic band 484 nm wavelength. Also the radiative temperature is measured in various high pressure range for tracing the ignition temperature in high pressure conditions.

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.5
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• pp.703-711
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• 2013

In this paper, we have proposed high power generator with Induction Voltage Adder of three cells. IVA which has n cells can generate n-th times high power pulse, is a more stable system than Marx generator in the view of breakdown. We applied amorphous metal magnetic cores as an energy storing material for IVA rather than ferrite cores because of their higher magnetic flux swing to make it more compact system and the loss of it was also considered in the design. For driving the IVA, we design Blumlein pulse generators which are filled with pure water for high dielectric constant and high breakdown field strength, and triggered by single Marx generator. We have presented the PSPICE simulation and its test result.

• Proceedings of the KIEE Conference
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• 2007.11c
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• pp.119-124
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• 2007

This research presented the new zero-current switching pulse width modulation SEPP(Single Ended Push-Pull)high frequency inverter for solving the problem of the zero-current SEPP high frequency inverter circuit which is using widely in the practical application of an induction heating apparatus, the soft switching operation and power control are impossible when the lowest power supply in the zero-current switching pulse width modulation SEPP high frequency inverter. The inverter circuit which is attempted by on-off operation of a switch has the reduction effect of the power loss due to a soft switching and a high frequency switching. And it confirmed that the power regulation is possible continuously from 0.25[kW] until 2.84[kW] in the case the duty rate(D) changes from 0.08 to 0.3 under zero-current switching operating by a dissymmetry pulse width modulating control and the power conversion efficiency comes true the efficiency of 95[%]. Due to the result above, the ZCS PWM SEPP high frequency inverter will be effective as sources of an induction heating apparatus.

• Proceedings of the Korea Contents Association Conference
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• 2011.05a
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• pp.5-6
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• 2011

사용자 중심의 감성공학으로 다변화 되어가는 유비쿼터스환경에서 디자인 요소와 결합시키는 상호작용이 요구되고 있으며 많은 연구가 진행되어 왔다. IT융합기술을 이용하여 감성 디자인을 제공하는 것은 제품 서비스 전략의 중요한 요소이다. 본 논문에서는 정보 필터링을 이용한 감성공학적 자동차 디자인 지원 방법론을 제안하였다. 제안된 방법은 사용자에게 자신의 감성에 부합하는 자동차 디자인을 제공함으로써 이를 얻기 위한 시간과 비용을 줄여주고, 손쉽게 원하는 디자인 스타일에 접근하도록 한다. 현실의 상황을 활용하고 정보 필터링으로 디자인을 추천함으로써 사용자에게 지능화된 개인화 서비스를 제공할 수 있다. 이를 사용자 인터페이스로 구축하여 논리적 타당성과 유효성을 검증하기 위해 실험적인 적용을 시도하고자 한다.