• Title/Summary/Keyword: hepatitis

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Overview of hepatitis B and C infection (B형 및 C형 간염의 이해)

  • Kim, Ji-Hoon
    • The Journal of the Korean life insurance medical association
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    • v.30 no.1
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    • pp.11-20
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    • 2011
  • Both the enterically transmitted forms of viral hepatitis, hepatitis A and E are self-limited and do not cause chroni chepatitis. Chronic hepatitis occurs in patients with hepatitis B and C as well as in patients with chronic hepatitis D superimposed on chronic hepatitis B. Chronic hepatitis such as hepatitis B or C is important in terms of insurance underwriting and claims. General review of hepatitis B and C was performed in this article.

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Disease Pattern Identification in Oriental Medicine and Herb Medicine treatment for Acute Hepatitis A with Jaundice : Case Series of 3 Patients (황달을 동반한 급성 A형 간염 환자 3예의 변증 분형과 인진(茵蔯)의 응용 치료)

  • Kim, Dong-Woung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.4
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    • pp.696-701
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    • 2010
  • Hepatitis A is acute hepatitis caused by the hepatitis A virus (HAV), HAV is a non-enveloped 27nm, heat-, acid, and ether-resistant RNA virus in the Picornavirus family. HAV is transmitted primarily through fecal-oral route and the incidence rate of hepatitis A is closely related to environmental hygiene and socioeconomic condition. Recent improvements in sanitation, public health policies, and socioeconomic development in South Korea have had great impact on the incidence of hepatitis A, which natural production of antibodies against HAV and the prevalence of HAV antibody has decreased. However, during the past ten years, symptomatic HAV infection substantially increased among juveniles and young adults in their twenties and thirties, and hepatitis A has become one of the most common acute hepatitis. Though there has been no report on treatment of hepatitis A with jaundice by oriental medicine in South Korea, many studies and case reports on treatment of icteric hepatitis of which main symptom is jaundice have been published in other countries. To treat patients diagnosed with hepatitis or suspected cases in oriental medicine hospitals, we need to have concerned about hepatitis A. This report is disease pattern identification in oriental medicine and treatments of 3 patients who were diagnosed with acute hepatitis A and treated in oriental medicine hospital.

The Association between Performance of Hepatitis B Vaccination and Health Belief Factors among Some Aged Persons (일부 노인의 B형간염 예방접종 이행과 건강신념과의 관련성)

  • Choi, Chun;Park, Jong;Kang, Myung-Guen;Kim, Ki-Soon
    • Korean Journal of Health Education and Promotion
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    • v.23 no.4
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    • pp.89-104
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    • 2006
  • Objectives: This study was done to find factors related with performance of hepatitis B Vaccination among some aged persons through health belief model. Methods: A questionnaire survey was made during September 2004 toward 230 elderly persons using institutions for the elderly of Gwangju City. The relations between subjects characteristics including health belief, mass media contact, hepatitis B experience and performance of hepatitis B vaccination were tested by t test or X2 test. Multiple logistic regression analysis was done to find final significantly related variables. Results: 24.8% of the subjects were vaccinated against hepatitis B. By simple analysis of relation between performance of hepatitis B vaccination and subjects characteristics including health belief, significant variables were chosen as 6 variables including perceived susceptibility, perceived seriousness, perception of benefits, knowledge on hepatitis B, age, experience of hepatitis through family or friend. After adjusting for confounding variables by multiple logistic regression analysis, hepatitis B vaccine performance showed significantly higher rate as the perception of disease seriousness increased(OR: 1.08, 95% CI: $1.03{\sim}1.14$) and in the group contacted with TV or radio information about hepatitis compared with non-contact. The group who experienced hepatitis among family or friends showed significantly higher hepatitis B vaccination performance rate compared with non-experienced. Conclusion: These results suggested that hepatitis B vaccine performance was related with health belief including hepatitis susceptibility, disease seriousness perception, acquisition of information through TV or radio and indirect hepatitis experience from family or friends.

Minocycline-Induced Autoimmune Hepatitis: A Rare But Important Cause of Drug-Induced Autoimmune Hepatitis

  • Harmon, Elizabeth G.;McConnie, Randolph;Kesavan, Anil
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.4
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    • pp.347-350
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    • 2018
  • Drug-induced autoimmune hepatitis (DIAIH) is an increasingly recognized form of drug-induced liver injury that leads to a condition similar to idiopathic autoimmune hepatitis. A number of drugs have been associated with DIAIH, minocycline is one of the most well characterized. Minocycline is a semisynthetic tetracycline antibiotic used in the treatment of acne vulgaris. Minocycline-induced autoimmune hepatitis presents with serologic and histologic features similar to idiopathic autoimmune hepatitis. However, the natural history and outcomes of these two conditions differ significantly. The majority of patients with minocycline-induced autoimmune hepatitis experience complete resolution of symptoms after withdrawal of the medication. Some patients may require a short course of steroids and rarely use of an immunomodulator to achieve resolution of disease. Recurrence of symptoms is rare and typically only occurs with reintroduction of minocycline. It is important for primary care providers to consider minocycline-induced autoimmune hepatitis when liver injury develops during minocycline therapy.

Viral Hepatitis and Liver Cancer on the Island of Guam

  • Haddock, R.L.;Paulino, Y.C.;Bordallo, R.
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3175-3176
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    • 2013
  • Patient records from the Guam Cancer Registry were compared with patients listed in a health department viral hepatitis case registry and the numbers of liver cancer and viral hepatitis cases were compared by ethnicity. Hepatitis C was the form of viral hepatitis most common among liver cancer cases on Guam (63.3% of viral hepatitis-associated liver cancer cases). Since viral hepatitis is an important cause of liver cancer, studies such as the present one may provide the information necessary to establish programs (screening of populations at risk and infant vaccination in the case of hepatitis B, for example) that may lessen the impact of liver cancer in the future.

Trends of the Global Hepatitis C Disease Burden: Strategies to Achieve Elimination

  • Brunner, Nathalie;Bruggmann, Philip
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.4
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    • pp.251-258
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    • 2021
  • Hepatitis C infection is responsible for high morbidity and mortality rates globally as well as for significant indirect costs. The disease burden caused by the hepatitis C virus (HCV) is comparable to the one caused by human immunodeficiency virus or tuberculosis. Today, simple detection methods, highly effective and easy to administer therapies and efficient preventative measures are available to combat hepatitis C. Nevertheless, in most countries around the world, the World Health Organization target of eliminating this infectious disease and its consequences by 2030 are not being met. Significant gaps in care for hepatitis C sufferers still exist, the shortcomings ranging from education and treatment to aftercare. Hepatitis C infection was and still is not on the radar of most politicians and health authorities. National programmes and strategies to combat the disease exist or are being developed in many countries. However, for these to be implemented efficiently and successfully, clear political commitment, strong civil society actors, well-functioning public health structures and the relevant support from global donors are needed.

Acute Viral Hepatitis A with Cholestatic Hepatitis Treated with Traditional Korean Medicine : A Case Report

  • Kim, Jun-Young;Joung, Jin-Yong;Kang, Ji-Young;Son, Chang-Gue;Cho, Jung-Hyo
    • The Journal of Korean Medicine
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    • v.36 no.4
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    • pp.114-121
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    • 2015
  • More and more patients suffering from hepatitis A, the number of patients representing symptoms that are uncharacteristic to hepatitis A is also increasing. There are occasions of serious complications among adult hepatitis A patients that can cause fulminant hepatitis or cirrhosis which can be fatal. A 43-year-old male was diagnosed as acute hepatitis A and was treated at a Western hospital over the course of three months, which included two months of hospitalization. However, his symptoms did not improve, so he was admitted to Oriental hospital. We prescribed Chunggan extract (CGX) four times a day. Acupuncture was performed twice a day. From the twenty-fourth day of admission, the total bilirubin fell under 10 mg/dL for the first time and next day he was discharged. Following his discharge, he consistently took CGX three times a day. 21 days after discharge all of his symptoms disappeared. This study demonstrated that traditional Korean medicine (TKM) for acute viral hepatitis with cholestatic hepatitis might be effective and safe with no adverse effects.

Natural History of Chronic Hepatitis in Korea (한국(韓國)에 만연(蔓延)하고 있는 만성간염(慢性肝炎)의 자연병력(自然病歷))

  • Chung, Whan-Kook
    • The Journal of the Korean life insurance medical association
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    • v.2 no.1
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    • pp.34-36
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    • 1985
  • Korea is an endemic area of chronic hepatitis in the world. Liver cirrhosis and liver cell carcinoma, presumed to be related to such chronic hepatitis, are the major causes of death in this country. The purpose of this study is disclosing the sources of chronic hepatitis in Korea establishing its histologic characteristics, disclosing the patterns of progression in chronic hepatitis, delineating its prognosis and finally speculating its etiology. The study group was composed of 183 patients with biopsy-proven acute icteric viral hepaticis, 32 patients with biopsy- proven anicteric hepatitis and 260 patients with biopsy- proven chronic hepatitis. These patients submitted to long-term follow-up by means of liver needle biopsy and/or clinicolaboratory evaluation. The period of follow-up ranged from two months to 18 years. The histological features of the initial biopsy specimens of chronic hepatitis permitted a division of the cases cases into the following five types: Type I. Persisting portal hepatitis : so called persisting hepatitis 43 Type II. Chronic inactive hepatitis with incomplete strand septal fibrosis. This type has thin fibrotic septation in addition to Type I with portal sclerosis 38 Type III. Chronic active periportal hepatitis(CAPH) : so called aggressive hepatitis, characterized by marked piecemeal necrosis. This type has been subdivided further into three groups: AB and C on the basis of histologic features. A CAPH without cirrhosis 15 B CAPH with cirrhosis 99 C CAPH with diffuse acinus type parenchymal nodules; characterized by rosette-forming micronodules 21 Type IV. Subacute hepatic necrosis; characterized by multilobular and/or bridging necrosis. 14 Type V. Persisting lobular hepatitis; characterized by spotty necrosis, which looks very similar to acute viral hepatitis. Such histologic changes should be persisted for more than six months 30 In Korea the main source of chronic hepatitis is the anicteric type. Of the chronic hepatitis observed in the hospital, Type IIIb was the most frequent in its incidence and occasionally exhibited development of hepatocellular carcinoma, but the mortality was highest in Type IIIc during the period of follow-up. Histologic characteristics of these five types suggest a spectrum of chronic hepatitis in Korea from an early and mild stage to advanced and fatal cirrhosis, which is occasionally associated with primary hepatic cell carcinoma. It seems that Type IV can be followed by flare-up of various stages of acute and chronic hepatitis with HBsAg and that many cases of liver cirrhosis prevalent in Korea occur through such an active process of Type IV. The etiology is not established, but in Korea it is mainly related to HBsAg.

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Knowledge, Health Belief, and Vaccination Behavior on Hepatitis A among University Students (대학생의 A형 간염에 대한 지식, 건강신념 및 예방접종 행태)

  • Kim, Kyung-Ja;Hwang, Tae-Yoon;Lee, Kyeong-Soo
    • Journal of agricultural medicine and community health
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    • v.41 no.3
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    • pp.119-128
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    • 2016
  • Objective: This study was to investigate the knowledge, health belief, and vaccination behavior on hepatitis A among university students. Methods: A self-administered questionnaire survey was conducted from $3^{rd}$ to $25^{th}$ March, 2014 and 197 subjects were enrolled in statistical analysis. Results: The result showed that the score for knowledge of the subjects on hepatitis A was $4.59{\pm}3.06$ out of 15 points, for health belief $2.39{\pm}0.28$ out of 4 points, and the vaccination rate of the subjects was 12.7%. There was significant difference in hepatitis A knowledge score according to experience of hepatitis A check-up and hepatitis A vaccination history of family members, and in health belief according to gender. For hepatitis A vaccination there was significant difference according to experience of hepatitis A check-up, family history of liver disease, hepatitis A vaccination history of family members, and education history of hepatitis A. As a result of logistic regression analysis experience of hepatitis check-up and hepatitis A vaccination history of family members were significant factors for hepatitis A vaccination. Conclusions: The level of knowledge, health belief for hepatitis A of the subjects was low and vaccination rate also low. The experience of hepatitis A check-up and hepatitis A vaccination history of family members were factors affecting hepatitis A vaccination. It would be necessary to develop programs for improving level of knowledge and health belief and raising the rate of hepatitis A vaccination for the university students in Korea.

The knowledge and attitudes towards hepatitis B among paramedic students (응급구조학과 대학생들의 B형간염에 대한 지식 및 태도)

  • Choi, Bo-Ram;Kim, Dong-Ok;Min, Gyung-Hun
    • The Korean Journal of Emergency Medical Services
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    • v.20 no.3
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    • pp.57-67
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    • 2016
  • Purpose: The purpose of this study was to investigate the knowledge and attitudes towards hepatitis B among paramedic students. Methods: A self-reported questionnaire was completed by 395 paramedic students in Daejeon and Chungnam from May 10 to June 10, 2016. The questionnaire consisted of general characteristics of the subjects (9 items), knowledge of hepatitis B (20 items), and attitudes towards hepatitis B (7 items). Data were analyzed by t test, ANOVA, post hoc Duncan test, and Pearson's correlation analysis using SPSS v. 23.0. Results: The knowledge of hepatitis B was 10.52(${\pm}5.18$) out of 20 points and was significantly correlated with grade, vaccination, or antibody-positive irerspective of education. The positive attitude toward hepatitis B was 3.15(${\pm}.43$) and there was a significant correlation with family history irrespective of education. There was a statistically positive correlation between the knowledge and attitudes towards hepatitis B (r=.104, p=.039). Conclusion: Precise knowledge delivery and full understanding of hepatitis B should be incorporated into the education of paramedic students. Active infection control by emergency medical technicians should be maintained by hepatitis B prevention practices.