• The Korean Journal of Physiology
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• 제2권1호
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• pp.17-21
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• 1968

Total body oxygen uptake was measured in rats following hemorrhage (16 rats) and blood transfusion (7 rats) under light Nembutal anesthesia. Arterial blood Pressure measured on the tail artery decreased or increased following hemorrhage or transfusion. No direct relationship was observed between arterial blood pressure alteration and oxygen intake variation. Hematocrit ratio which changed after hemorrhage or transfusion showed a direct relationship with oxygen intake. Decrease in hematocrit ratio resulted in a decrease in oxygen intake of rats. The correlation coefficient between decrement of hematocrit ratio and decrement of oxygen intake was r=.56. The correlation coefficient between increment of hematocrit ratio and increment of oxygen intake was r=.86. Thus it was concluded that alteration in oxygen intake was limited by the systemic oxygen transport capacity of blood.

• Journal of Korean Neurosurgical Society
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• 제44권6호
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• pp.405-408
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• 2008

GBM is the most common primary brain tumor, but intraventricular GBM is rare and only few cases have been reported in the literature. The authors report a case of 64-year-old man who had a remote history of previous periventricular intracerebral hemorrhage. Brain computed tomography (CT) and magnetic resonance (MR) imaging showed an intraventricular lesion with inhomogeneous enhancement, infiltrative borders and necrotic cyst, and obstructive hydrocephalus. The patient underwent surgical removal through transcortical route via the bottom of previous hemorrhage site and the final pathologic diagnosis was GBM. We present a rare case of an intraventricular GBM with detailed clinical course, radiological findings, and pathological findings, and the possible origin of this lesion is discussed.

• Journal of Korean Neurosurgical Society
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• 제41권5호
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• pp.336-339
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• 2007

Traumatic intracranial aneurysm rarely occurs after a head injury. The authors report a case of a 51-year-old man in whom subarachnoid hemorrhage was developed as a result of delayed traumatic aneurysmal rupture of the distal portion of the middle cerebral artery following a minor, closed-head injury. The unruptured aneurysm had been evident on the magnetic resonance image taken two days prior to onset of the subarachnoid hemorrhage. The clinical presentation and possible underlying mechanism are discussed with a review of pertinent literature.

• 동의생리병리학회지
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• 제26권6호
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• pp.960-963
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• 2012

Cavernous angiomas of the medulla oblongata are rare vascular malformations. We report a case of cavernous angioma with medullary hemorrhage showing symptoms of diplopia and weakness of right extremities. We treated a patient with herb medicine, acupuncture and moxibustion. This study suggests that oriental medicine therapy has a significant effect on the symptoms of medullary hemorrhage.

• Journal of Korean Neurosurgical Society
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• 제51권1호
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• pp.37-39
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• 2012

We present a rare case of massive intracerebral hemorrhage resulting from a small, superficially-located supratentorial cavernous malformation, or cavernoma. These lesions rarely lead to massive, life-threatening intracerebral hemorrhages. A 17-year-old female presented with a 3-week history of declining mental status. Brain computed tomography and magnetic resonance imaging revealed a sizable intracranial hemorrhage, within the right occipital region, associated with a small nodule at the hematoma's posterior margin. An emergency operation removed the entire hematoma and nodule. Histological examination of the nodule was compatible with a diagnosis of cavernous malformation. The patient's post-operative course was uneventful.

• Journal of Korean Neurosurgical Society
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• 제39권6호
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• pp.459-463
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• 2006

This report describes a case of diffuse neurofibroma[DNF] that presented with spontaneous intratumoral hemorrhage. A 31-year-old man with cutaneous manifestations typical of neurofibromatosis type 1[NF1] was referred to hospital with a progressively expanding scalp swelling. Magnetic resonance imaging[MRI] showed an acute hematoma surrounded by a dense mass on the parietooccipital scalp. Plain skull radiographs and a computed tomography[CT] scan revealed bony defects in the occipital bone around the lambdoid suture and the skull base, including the sphenoid and petrous bones. The tumor extended to the upper cervical region and infiltrated through the fascia of the musculature. The tumor and adjacent soft tissue were highly vascular, which made surgical resection difficult. We describe the clinical, radiological and pathological features of this patient md discuss the surgical methods used to avoid a life-threatening hemorrhage during surgery.

• Journal of Korean Neurosurgical Society
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• 제53권6호
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• pp.380-382
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• 2013

We report a case of fatal duret hemorrhage (DH) in a patient with acute tentorial subdural hematoma and bilateral chronic subdural hematoma along the cerebral hemispheres. Preoperative CT angiography (CTA) revealed prominent parenchymal enhancement in the ventral pontomesencephalic area. After burr-hole drainage, a large hemorrhage developed in this area. The parenchymal enhancement in the CTA may reflect the pontomensencephalic perforating vessel injury, and may be a sign of impending DH of acute transtentorial downward herniation. Previous use of aspirin and warfarin might have potentiated the process of DH and increase the extent of the bleed.

• 대한한방부인과학회지
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• 제27권4호
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• pp.121-132
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• 2014

Objectives: The purpose of this study is to report the effects of herbal medicine on corpus luteum and luteal hemorrhage. Ovulation is a physical event and hemorrhage from corpus luteum is known to occur in reproductive age group women. Life threatening hemorrhage requires surgical intervention and blood transfusion. Methods: The patients of this study are 34-year-old and 16-year-old females. They were diagnosed as the hemorrhagic corpus luteal cyst. Two patients was advised to be operated beacause of rupture possibility. They were treated by traditional Korean Medicine, herbal medicine (Bokryungdosu-tang), acupuncture and moxibustion. Results: After the treatment, the patients recovered their condition. One patient was diagnosed with disappearance of existing corpus luteum, the other was relieved of heavy abdominal pain, vaginal discharge and lumbago. Conclusions: Thess cases show that traditional Korean treatment might be effective on corpus luteum and luteal hemorrhage.

• Tuberculosis and Respiratory Diseases
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• 제84권4호
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• pp.255-262
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• 2021

Microscopic polyangiitis (MPA) is an antineutrophil cytoplasmic antibody (ANCA)-associated necrotizing vasculitis, which mainly affects small vessels in various organs, especially the lungs. The two key pulmonary manifestations, interstitial lung disease (ILD) and diffuse alveolar hemorrhage (DAH), increase the morbidity and death rate of patients with MPA. ILD is more common in MPA than in other ANCA-associated vasculitis subsets and is primarily associated with myeloperoxidase-ANCA. Unlike alveolar hemorrhage due to pulmonary capillaritis, ILD can initially manifest as isolated pulmonary fibrosis. Of note, its most frequent radiographic pattern is the usual interstitial pneumonia pattern, similar to the characteristic pattern seen in idiopathic pulmonary fibrosis. In this review we present the pathogenesis, clinical manifestations, and radiographic and histopathologic features of ILD and DAH in MPA. We also briefly summarize the outcome and therapeutic options for the two conditions.

• Annals of Geriatric Medicine and Research
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• 제22권4호
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• pp.200-203
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• 2018

Strongyloides stercoralis is an intestinal nematode that occurs sporadically in temperate areas like Korea. People who are in the immunosuppressed state, over the age of 65 or under the corticosteroid therapy are at risk for developing Strongyloides hyperinfection syndrome. Acute respiratory distress syndrome (ARDS) with alveolar hemorrhage is a rare presentation of Strongyloides hyperinfection. A 78-year-old man had been irregularly injected corticosteroid on his knees, but did not have any immunosuppressive disease. He was initially diagnosed with ARDS and septic shock. Bronchoalveolar lavage (BAL) fluid was bloody and its cytology revealed helminthic larvae identified as S. stercoralis. Results of Cytomegalovirus polymerase chain reaction (PCR), Pneumocystis jirovecii PCR, and Aspergillus antigen testing of the BAL fluid were positive. The clinical progress quickly deteriorated with multiple organ failure, shock and arrhythmia, so he finally died. This is a rare case of ARDS in an older patient without any known immunosuppressive conditions, with alveolar hemorrhage and S. stercoralis being found via BAL.