• Title/Summary/Keyword: hemA

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Facial fractures and associated injuries in high- versus low-energy trauma: all are not created equal

  • Hilaire, Cameron St.;Johnson, Arianne;Loseth, Caitlin;Alipour, Hamid;Faunce, Nick;Kaminski, Stephen;Sharma, Rohit
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.22.1-22.6
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    • 2020
  • Introduction: Facial fractures (FFs) occur after high- and low-energy trauma; differences in associated injuries and outcomes have not been well articulated. Objective: To compare the epidemiology, management, and outcomes of patients suffering FFs from high-energy and low-energy mechanisms. Methods: We conducted a 6-year retrospective local trauma registry analysis of adults aged 18-55 years old that suffered a FF treated at the Santa Barbara Cottage Hospital. Fracture patterns, concomitant injuries, procedures, and outcomes were compared between patients that suffered a high-energy mechanism (HEM: motor vehicle crash, bicycle crash, auto versus pedestrian, falls from height > 20 feet) and those that suffered a low-energy mechanism (LEM: assault, ground-level falls) of injury. Results: FFs occurred in 123 patients, 25 from an HEM and 98 from an LEM. Rates of Le Fort (HEM 12% vs. LEM 3%, P = 0.10), mandible (HEM 20% vs. LEM 38%, P = 0.11), midface (HEM 84% vs. LEM 67%, P = 0.14), and upper face (HEM 24% vs. LEM 13%, P = 0.217) fractures did not significantly differ between the HEM and LEM groups, nor did facial operative rates (HEM 28% vs. LEM 40%, P = 0.36). FFs after an HEM event were associated with increased Injury Severity Scores (HEM 16.8 vs. LEM 7.5, P <0.001), ICU admittance (HEM 60% vs. LEM 13.3%, P <0.001), intracranial hemorrhage (ICH) (HEM 52% vs. LEM 15%, P <0.001), cervical spine fractures (HEM 12% vs. LEM 0%, P = 0.008), truncal/lower extremity injuries (HEM 60% vs. LEM 6%, P <0.001), neurosurgical procedures for the management of ICH (HEM 54% vs. LEM 36%, P = 0.003), and decreased Glasgow Coma Score on arrival (HEM 11.7 vs. LEM 14.2, P <0.001). Conclusion: FFs after HEM events were associated with severe and multifocal injuries. FFs after LEM events were associated with ICH, concussions, and cervical spine fractures. Mechanism-based screening strategies will allow for the appropriate detection and management of injuries that occur concomitant to FFs. Type of study: Retrospective cohort study. Level of evidence: Level III.

Helicopter-borne electromagnetic surveys for civil engineering in Japan

  • Konishi Naotoshi;Ashida Yuzuru
    • 한국지구물리탐사학회:학술대회논문집
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    • 2003.11a
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    • pp.422-431
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    • 2003
  • Helicopter-borne electromagnetic (HEM) systems were originally developed for the exploration of mineral deposits. The frequency range of a conventional HEM system for mineral exploration, however, is relatively low and so not invariably suitable for its application to the fields of civil engineering because of its poor resolution in the shallower part of the earth. A DIGHEM HEM system was acquired by Nippon Engineering, with the frequencies chosen by the senior author. The five frequencies range from 220 Hz (the lowest) to 137,500 Hz (the highest). These frequencies improve the resolution of materials in the shallower part while maintaining a depth of investigation of greater than 100 m. This paper describes six case histories of geological and geotechnical surveys for civil engineering using HEM. These case histories include HEM surveys for investigating landslide, an alluvial area, root selection of road construction, areas related to dam and tunnel construction, and the simultaneous joint inversion of HEM and CSAMT data for a deep tunnel. These survey results show that HEM has sufficient resolution in both horizontal and vertical directins to contribute significantly to outlining the regional geology and its engineering problems.

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Visual Evaluation according to Changes in Length of Pants and Width of Hem Line of Wide Pants (와이드팬츠의 바지 길이와 바지 부리 폭 변화에 따른 시각적 평가)

  • Lee, Jung-Jin
    • Journal of the Korea Fashion and Costume Design Association
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    • v.17 no.3
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    • pp.159-168
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    • 2015
  • In this study, visual evaluation was wide pants with changes in length of pants and width of hem line of wide pants design to provide data which can enhance wearing image effects at the production of wide pants. According to the length of pants and width of hem line of wide pants, a total of 9 stimulants were chosen. Then, they were evaluated using a seven-point rating scale against 40 fashion students. The data has been analyzed by Factor Analysis, ANOVA, $Scheff{\acute{e}}$'s Test and the MCA method. The results of the study are as follows : 1. According to factor analysis, the components of visual evaluation depending on the length of pants and width of hem line of wide pants were divided into five factors: individuality, body correction, modesty, body length and cute. 2. According to visual evaluation depending on changes in the length of pants, no significant difference was found in all five positions. 3. According to visual evaluation depending on changes in the length of pants and width of hem line of wide pants, 'width of hem line 60, 100' revealed a significant difference in body correction. 'width of hem line 80' revealed a significant difference in body correction and body length. 4. In terms of interactions over changes in the length of pants and width of hem line of wide pants, no interaction effects were found in all five factors. According to multiple classification analysis(MCA) on the factors without interaction effects, length of pants had more effect on visual image in body correction, body length and cute. In other factors, more influence was observed depending on the width of hem line.

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Effect of Gene Amplifications in Porphyrin Pathway on Heme Biosynthesis in a Recombinant Escherichia coli

  • Lee, Min Ju;Kim, Hye-Jung;Lee, Joo-Young;Kwon, An Sung;Jun, Soo Youn;Kang, Sang Hyeon;Kim, Pil
    • Journal of Microbiology and Biotechnology
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    • v.23 no.5
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    • pp.668-673
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    • 2013
  • A recombinant E. coli co-expressing ALA synthase (hemA), NADP-dependent malic enzyme (maeB), and dicarboxylic acid transporter (dctA) was reported to synthesize porphyrin derivatives including iron-containing heme. To enhance the synthesis of bacterial heme, five genes of the porphyrin biosynthetic pathway [pantothenate kinase (coaA), ALA dehydratase (hemB), 1-hydroxymethylbilane synthase (hemC), uroporphyrinogen III synthase (hemD), and uroporphyrinogen III decarboxylase (hemE)] were amplified in the recombinant E. coli co-expressing hemA-maeB-dctA. Pantothenate kinase expression enabled the recombinant E. coli to accumulate intracellular CoA. Intracellular ALA was the most enhanced by uroporphyrinogen III synthase expression, porphobilinogen was the most enhanced by ALA dehydratase expression, uroporphyrin and coproporphyrin were the most enhanced by 1-hydroxymethylbilane synthase expression. The strain co-expressing coaA, hemA, maeB, and dctA produced heme of $0.49{\mu}mol/g$-DCW, which was twice as much from the strain without coaA expression. Further pathway gene amplifications for the porphyrin derivatives are discussed based on the results.

Expression of yeast Hem1 gene controlled by Arabidopsis HemA1 promoter improves salt tolerance in Arabidopsis plants

  • Zhang, Zhi-Ping;Yao, Quan-Hong;Wang, Liang-Ju
    • BMB Reports
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    • v.43 no.5
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    • pp.330-336
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    • 2010
  • 5-Aminolevulinate (ALA) is well-known as an essential biosynthetic precursor of all tetrapyrrole compounds, which has been suggested to improve plant salt tolerance by exogenous application. In this work, the gene encoding aminolevulinate synthase (ALA-S) in yeast (Saccharomyces cerevisiae Hem1) was introduced into the genome of Arabidopsis controlled by the Arabidopsis thaliana HemA1 gene promoter. All transgenic lines were able to transcribe the YHem1 gene, especially under light condition. The chimeric protein (YHem1-EGFP) was found co-localizing with the mitochondria in onion epidermal cells. The transgenic Arabidopsis plants could synthesize more endogenous ALA with higher levels of metabolites including chlorophyll and heme. When the $T_2$ homozygous seeds were cultured under NaCl stress, their germination and seedling growth were much better than the wild type. Therefore, introduction of ALA-S gene led to higher level of ALA metabolism with more salt tolerance in higher plants.

A Study on the Visual Evaluation According to Changes in Width of Hem Line and Waistline Position of Flare Pants (플레어 팬츠의 바지부리 폭과 허리선 위치의 변화에 따른 시각적 평가)

  • Lee, Jung-Soon
    • Journal of the Korea Fashion and Costume Design Association
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    • v.14 no.4
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    • pp.127-137
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    • 2012
  • The purpose of this study is to recognize the differences of visual evaluation by variations in width of hem line and waistline position of the flare pants. The stimuli are 9 samples: One control group, 3 variations of the width of hem line and 3 variations of the waistline position. The data has been obtained from 44 fashion students. The data has been analyzed by Factor Analysis, Anova, Scheffe's Test and the MCA method. The results of the study are as follows: The visual evaluation by the width of hem line and waistline position of flare pants are composed of 5 factors : physical characteristics, elegance, originality, comfort, and stiffness. Among these factors, the physical characteristic is evaluated to be the most important factor. As a v isual evaluation result o f changes in the width o f hern l ine, 8 4 cm in width (the narrowest width) was highly evaluated in physical characteristics, elegance, and originality factors. For the result of changes in the waistline position, high-waisted flare pants were highly effective in physical characteristics, and also evaluated well in elegance, originality and stiffness factors. The flare pants did not show any interaction between the width of hem line and waistline position. The waistline position had more influence on visual evaluation in physical characteristics, originality and comfort factors while elegance and stiffness factors were affected by the width of hem line.

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A Study on Drapability for Construction of Skirt -Mainly dealing with the Drape-Coefficient and Hem-Effect- (Skirt 구성 면에서 본 Drap 성에 관한 연구 -Drape 계수와 Hem 효과를 중심으로-)

  • Suh Young Suk;Park Young Deuk
    • Journal of the Korean Society of Clothing and Textiles
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    • v.5 no.2
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    • pp.49-53
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    • 1981
  • This study was carried out to investigate the drapability of polyester double jersey skirt Drapability is an important aesthetic properties of fabric on clothing construction, In this thesis weight, shearing, bending and non-isotropic characteristics of fabric were regarded as important factors of drapability, Especially for drapability of skirt, I investigated hem effect on various length of hem and skirt, The results were as follows, 1. The less the weight of fabric was, the greater drapability appeared. On fabrics, large pliability and modulus of shear have good drapability, 2. On clothing cutting, non-isotropic property affected on drapability of clothes remark-ably. Drapability order of clothes was greatest in bias direction, next in wale, course direction, 3. The shorter the skirt length and closer at hem line were the larger the hem effect influence upon the drapability of skirt was.

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A Study on the Visual Evaluation According to Changes in Silhouette of Wide Pants (와이드 팬츠의 실루엣 변화에 따른 시각적 평가)

  • Lee, Jung-Soon
    • Journal of the Korea Fashion and Costume Design Association
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    • v.15 no.1
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    • pp.21-30
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    • 2013
  • The purpose of this study is to recognize the differences of visual evaluation by variations in silhouette of the wide pants. The stimuli are 9 samples: One control group, 3 variations of the width of hem line and 3 variations of the silhouette. The data has been obtained from 57 fashion college students. The data has been analyzed by Factor Analysis, Anova, Scheffe's Test. The results of the study are as follows: The visual evaluation by silhouette of wide pants are composed of 5 factors(i.e., physical characteristics, complexity, attractiveness, originality, and stiffness and softness). Among these factors, the physical characteristic is evaluated to be the most important factor. The straight pants were the most attractive and modern when the width of the hem line was 66cm (1st stage), while the pants were uncomfortable and unwearable when the width of the hem line was 98cm (3rd stage). The bell-bottom pants were evaluated to be the most attractive with the average width of the hem line. When the width of the hem line of the flare pants were too wide, it was uncomfortable and unwearable but had its unique originality. When the width of the hem line was narrow, the visual image changed as the pants' silhouette varied. However, when the width of the hem line was wide, the visual image did not change by silhouette.

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Quantitation of n-Hexane Extractable Material (HEM) and Estimation of Annual Pollutant Loading Rate by Sewage Sludge Applicated to Land (하수슬러지 중 노말헥산추출물질 (HEM) 함량 분석 및 토양 시용시 연간 오염부하량 추정)

  • Nam, Jae-Jak;Park, Woo-Kyun;Lim, Dong-Kyu;Lee, Sang-Hak
    • Korean Journal of Environmental Agriculture
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    • v.21 no.1
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    • pp.45-49
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    • 2002
  • To estimate annual pollutant loading rate of n-hexane extractable material (HEM) to soil 84 sewage sludge samples were analyzed. The average content of HEM was 27.7$\pm$26.5 g/kg, and ranged from 1.05 to maximum 194 g/kg. According to the number of population of the city the areas were classified as five regions, i.e. big, large, middle, small, and rural area in which the waste water treated plants were grown. The contents of HEM were 22.7$\pm$16.7, 33.3$\pm$25.8, 22.0$\pm$8.7, 31.0$\pm$38.8, 27.7$\pm$25.1 g/kg, in big, large, middle, small, and rural area, respectively. The applicated areas with sewage sludge to land also were divided as 4 sites by US EPA criteria such as agricultural, forest, public contact sites, and reclamation site. The quantitation of annual pollutant loading rate was estimated using a function (99 percentile concentration = $\bar{X}$ + 3$\sigma$) when the application amounts were in dosages of 7,000, 26,000, 18,000, 74,000 kg/ha in 5 regions, respectively. The annual pollutant loading rate of HEM to soil by sewage sludge application was maximum 1,032, 3,832, 2,653, and 10,908 kg/ha in agricultural, forest, public contact sites, and reclamation site, respectively.

The Calculating Method Study of the Hem Circumference in Designing Flare Skirt (Flare Skirt 디자인의 밑단 둘레 계산방법(計算方法) 연구(硏究))

  • Jeong, Hyung-Do;Park, Jeong-Ae;Yoo, Tai-Soon
    • Journal of Fashion Business
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    • v.1 no.4
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    • pp.49-54
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    • 1997
  • Methods of the flare skirt pattern making are presented variously among foreign and domestic test books. Three of them are : First the method is using the basic skirt pattern, secondly the method is quartering rectangle of skirt length $\times\frac{W}4$, finally the method is substituting waist size for formula. But, these books don't include the calculating method of the hem circumference. This calculating method express the shape of flare skirt and the using length of trimming -race and frill-. This study aims at proposing the calculating formula of the hem circumference and the standardization of pattern making technical skill. The result were as follows. 1. The calculating formula of hem circumference had regular ratio in $180^{\circ}$, $270^{\circ}$ and $360^{\circ}C$ flare. That was (HEM) = $(\frac{(5\;{\times}\;(W\;+\;1)}{4\;{\times}\;A}+(SK.L))\;{\times}\;A\;{\times}\;0.785$. A was 4 in $180^{\circ}$, 6 in $270^{\circ}$, 8 in $360^{\circ}$. 2. The error of hem circumference from 46 to 86 centimeter of waist size was between 0.11875 and -0.63125 centimeter in $180^{\circ}$, $270^{\circ}$ and $360^{\circ}$ flare skirt. This formula was less in the error.

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