• Journal of the Korea Society for Simulation
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• v.21 no.2
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• pp.69-78
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• 2012

In this paper, a study on finding an appropriate helper node that can help increase effective frame transmission rate for cooperative communications at ad hoc networks is carried out. Those researches from reference use the reactive helper node selection mechanism which starts its role after exchanging RTS and CTS frames between source and destination nodes, and are implemented into our simulator for performance comparison. System throughput and average channel access delay are used for performance measures and all communicating nodes are assumed to move independently within the communication range. It is anticipated that this research result can be used as basic information for designing a new efficient helper node selection scheme.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.7
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• pp.1397-1405
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• 2012

Cooperative communications play a important role in increasing frame transmission rate at wireless communication networks where frequency resource is strictly limited. In this paper, we did a research on how to select the helper nodes that are very import in cooperative communications. As a prelude study in this research field, we carried out performance comparison of three helper node selection schemes using computer simulation. The system throughput was used as the performance measure and the random way point mobility model, where every communicating nodes move around within the designated communication range, was used.

• Journal of information and communication convergence engineering
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• v.12 no.4
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• pp.199-207
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• 2014

A new cooperative MAC protocol called the busy tone cooperative medium access control (BT-COMAC) protocol is proposed to overcome the drawbacks and maximize the advantages of existing schemes. This scheme uses a new metric called decibel power to decide an appropriate helper node. Using received power strength is more efficient in selecting an appropriate helper node, especially in a densely populated network, than the effective transmission rates used in conventional schemes. All communication nodes in a communication service area are assumed to move independently. Two performance metrics are used: System throughput and channel access delay. A performance evaluation of the BT-COMAC protocol is conducted using a computer simulation over a slow fading wireless channel, and its performance results are compared with those of four existing schemes. The numerical results show that the BT-COMAC protocol improves the system throughput by approximately 15% as compared to the best existing scheme.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.11
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• pp.2636-2656
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• 2013

To improve the cooperative efficiency of node cooperation and multiple access performance for multihop wireless networks, a priority-differentiated cooperative medium access control protocol with contention resolution (CRP-CMAC) is proposed. In the protocol, the helper selection process is divided into the priority differentiation phase and the contention resolution phase for the helpers with the same priority. A higher priority helper can choose an earlier minislot in the priority differentiation phase to send a busy tone. As a result, the protocol promptly selects all the highest priority helpers. The contention resolution phase of the same priority helpers consists of k round contention resolution procedures. The helpers that had sent the first busy tone and are now sending the longest busy tone can continue to the next round, and then the other helpers that sense the busy tone withdraw from the contention. Therefore, it can select the unique best helper from the highest priority helpers with high probability. A packet piggyback mechanism is also adopted to make the high data rate helper with packet to send transmit its data packets to its recipient without reservation. It can significantly decrease the reservation overhead and effectively improve the cooperation efficiency and channel utilization. Simulation results show that the maximum throughput of CRP-CMAC is 74%, 36.1% and 15% higher than those of the 802.11 DCF, CoopMACA and 2rcMAC protocols in a wireless local area network (WLAN) environment, and 82.6%, 37.6% and 46.3% higher in an ad hoc network environment, respectively.

• Journal of Veterinary Clinics
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• v.8 no.1
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• pp.1-10
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• 1991

The B-lymphocyte differentiation from committed B-cell progenitors to antibody-secreting cells was discussed. B-cell progenitors derived from hematopoietic stem cells undergo the rearrangement of immunoglobulin(Ig) gene. The earliest cells as B-cell precursors have cytoplasmic Is(${\mu}$ chain). The entire Is molecule is expressed on the surface after synthesis of L chain. The resting B cells(Go stage) stimulated by binding antigen via Ig-receptors are activated(G$_1$ stage) and followed by proliferation(S stage), coupled with further selection(affinity maturation. class switch). The production of antibody against a particular antigen depends on the activation of B cells with surface Is capable of reacting with that antigen. This process does not occur in isolation but is controlled by helper and suppressor T cells and antigen presenting cells(APC). The mechanism of T cell-dependent B-cell response for production of antibody is largely explained by the cell to cell cooperation and soluble helper factors of T cells. 1) The antigen specific B cells and helper T cells are linked by Is-receptors, leading to the delivery of helper signals to the B cells. 2) Helper T cells recognize the processed antigen-derived peptides with the MHC class II molecules(la antigen) and is stimulated to secrete B-cell proliferation and differentiation factors which activate B cells of different antigenic specificity. The two models are shown currently 1) At low antigen concentration, only the antigen-specific B cell binds antigen and presents antigen-derived peptides with la molecules to helper T cells, which are stimulated to secrete cytokines(IL-4, IL-5, etc.) and 2) At high antigen concentration, antigen-derived peptides are presented by specific B cells, by B cells that endocytose the antigens, as well as by APC Cytokines secreted from helper T cells also lead to the activation of B cells and even bystander B cells in the on- vironmment and differentiate them into antibody-secreting plasma cells.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.8
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• pp.1811-1819
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• 2013

In this paper, we carried out a study on how to find an appropriate helper node for cooperative communications, the role of which is very import to enhance system throughput of wireless communication system. The busy tone cooperative MAC (BT-COMAC) protocol proposed in this paper is a new cooperative MAC protocol with a reactive helper node scheme and maximizes the benefits of existing schemes while making up for their shortcomings. We conducted performance evaluation of this new protocol using computer simulation experiment. System throughput in bps and channel access delay are utilized as performance measures. We used a random way point mobility model where every communication node moves independently one another, and slow fading channel where every communication node decided its transmission rate with received power basis. Numerical results show that the new MAC protocol enhances system throughput as much as 15% of the existing scheme.

• Molecules and Cells
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• v.38 no.3
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• pp.195-201
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• 2015

Antibodies are powerful defense tools against pathogens but may cause autoimmune diseases when erroneously directed toward self-antigens. Thus, antibody producing cells are carefully selected, refined, and expanded in a highly regulated microenvironment (germinal center) in the peripheral lymphoid organs. A subset of T cells termed T follicular helper cells (Tfh) play a central role in instructing B cells to form a repertoire of antibody producing cells that provide life-long supply of high affinity, pathogenspecific antibodies. Therefore, understanding how Tfh cells arise and how they facilitate B cell selection and differentiation during germinal center reaction is critical to improve vaccines and better treat autoimmune diseases. In this review, I will summarise recent findings on molecular and cellular mechanisms underlying Tfh generation and function with an emphasis on T cell costimulation.

• Proceedings of the KSME Conference
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• 2001.06b
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• pp.325-329
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• 2001

This paper addresses a control architecture for the hospital service robot, SmartHelper. With a sensing-reasoning-acting paradigm, the deliberation takes place at planning layer while the reaction is dealt through the parallel execution of operations. Hence, the system presents both a hierarchical and an heterarchical decomposition, being able to show a predictable response while keeping rapid reactivity to the dynamic environment. The deliberative controller accomplishes four functions which are path generation, selection of navigation way, command and monitoring. The reactive controller uses fuzzy and potential field method for robot navigation. Through simulation under a virtual environment IGRIP, the effectiveness of the control architecture is verified.

• Journal of Microbiology
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• v.37 no.2
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• pp.97-101
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• 1999

Random hexapeptide library on the surface of filamentous bacteriophage was constructed using the SurfZAP vector. The size of the library was approximately 105. The peptide insert was flanked by two cysteines to constrain the peptide structure with a disulfide bond. This library was screened for the topoisomerase II binding peptide. Dramatic enrichment of the fusion phage over the VCS M13 helper phage was demonstrated by bio-panning affinity selection.

• Human Ecology Research
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• v.58 no.3
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• pp.343-356
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• 2020

This paper examines the associations of having a helper for domestic work or childcare and time spent on it by couples in South Korea. We use five waves of panel survey data from the Korean Longitudinal Survey of Women and Families (KLoWF), which allows longitudinal changes within couples over time that account for potential selection effects and unobserved heterogeneity among individuals. With fixed effects, we find outsourcing is associated with a decrease in wife's time spent on domestic work or childcare by 1 hour per week. However, the decrease is concentrated on the unemployed wife's time, but not employed wife's time. In addition, outsourcing is not a significant factor for husband's time and the husband's share of total contribution. This may be because wives are the main provider of domestic work and childcare in Korea regardless of employment status or having any helper. Due to unequal contributions between husband and wife, using outsourcing also neither alleviates the employed wife's contribution nor changes the husband's contribution. However, the results may be underestimated because there are more common and diverse types of outsourcing in a broad sense, such as going out for dinner, buying prepared food, and using dry cleaning services. We expect future studies to consider more broad types of outsourcing and examine how relations with the couple's time use at home are different by type.