• Nuclear Engineering and Technology
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• v.35 no.5
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• pp.426-441
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• 2003

A reactor inlet header break experiment, B9401, performed in the RD-14M multi channel test facility was analyzed using RELAP5/MOD3.2 and RELAP5/CANDU[1]. The RELAP5 has been developed for the use in the analysis of the transient behavior of the pressurized water reactor. A recent study showed that the RELAP5 could be feasible even for the simulation of the thermal hydraulic behavior of CANDU reactors. However, some deficiencies in the prediction of fuel sheath temperature and transient behavior in athe headers were identified in the RELAP5 assessments. The RELAP5/CANDU has been developing to resolve the deficiencies in the RELAP5 and to improve the predictability of the thermal-hydraulic behaviors of the CANDU reactors. In the RELAP5/CANDU, critical heat flux model, horizontal flow regime map, heat transfer model in horizontal channel, etc. were modified or added to the RELAP5/MOD3.2. This study aims to identify the applicability of both codes, in particular, in the multi-channel simulation of the CANDU reactors. The RELAP5/MOD3.2 and the RELAP5/CANDU analyses demonstrate the code's capability to predict reasonably the major phenomena occurred during the transient. The thermal-hydraulic behaviors of both codes are almost identical, however, the RELAP5/CANDU predicts better the heater sheath temperature than the RELAP5/MOD3.2. Pressure differences between headers govern the flow characteristics through the heated sections, particularly after the ECI. In determining header pressure, there are many uncertainties arisen from the complicated effects including steady state pressure distribution. Therefore, it would be concluded that further works are required to reduce these uncertainties, and consequently predict appropriately thermal-hydraulic behaviors in the reactor coolant system during LOCA analyses.

• Bulletin of the Korean Chemical Society
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• v.29 no.9
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• pp.1717-1722
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• 2008

The 70 kDa heat-shock protein (Hsp70) involved in various cellular functions, such as protein folding, translocation and degradation, regulates apoptosis in cancer cells. Recently, it has been reported that the green tea flavonoid (−)-epigallocatechin 3-gallate (EGCG) induces apoptosis in numerous cancer cell lines and could inhibit the anti-apoptotic effect of human Hsp70 ATPase domain (hATPase). In the present study, docking model between EGCG and hATPase was determined using automated docking study. Epi-gallo moiety in EGCG participated in hydrogen bonds with side chain of K71 and T204, and has metal chelating interaction with hATPase. Hydroxyl group of catechin moiety also participated in metal chelating hydrogen bond. Gallate moiety had two hydrogen bondings with side chains of E268 and K271, and hydrophobic interaction with Y15. Based on this docking model, we determined two pharmacophore maps consisted of six or seven features, including three or four hydrogen bonding acceptors, two hydrogen bonding donors, and one lipophilic. We searched a flavonoid database including 23 naturally occurring flavonoids and 10 polyphenolic flavonoids with two maps, and myricetin and GC were hit by map I. Three hydroxyl groups of B-ring in myricetin and gallo moiety of GC formed important hydrogen bonds with hATPase. 7-OH of A-ring in myricetin and OH group of catechin moiety in GC are hydrogen bond donors similar to gallate moiety in EGCG. From these results, it can be proposed that myricetin and GC can be potent inhibitors of hATPase. This study will be helpful to understand the mechanism of inhibition of hATPase by EGCG and give insights to develop potent inhibitors of hATPase.

• Journal of the Korean Society of Propulsion Engineers
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• v.11 no.3
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• pp.20-28
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• 2007

The easiest way to see the phenomena of compressor surge is to show the static and dynamic operation characteristic on the map. Its operation zone will be restricted by the surge limit and, static and transient process must have some margin for it. Effect of rotor moment of inertia, air/gas volumes and heat transfer are factors to cause the transition from the static line. In case a large volume such as heat exchanger exists in the system it will exert a substantial influence to dynamic characteristics. In the present paper, influence of air volume bled from the compressor exit on transient process is investigated with an example of an auxiliary power unit micro-turbine engine. Turbine mass, pressure ratio, rotation speed, power and moment are calculated based on mass and work conservation. Result from the present study can give guidance to design the control system. A computer program is developed to calculate the dynamic process using the MathCAD commercial software.

• Journal of the Korean Geographical Society
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• v.40
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• pp.1-13
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• 1989

The brightness temperature from NOAA AVHRR CH 4 images was examined for the metropolitan Seoul area, the capital city of Korea, to detect the characteristics of the urban heat island for this study. Surface data from 21 meteorological stations were compared with the brightness temperatures Through computer enhancement techniques, more than 20 heat islands could be recognized in South Korea, with 1 km spatii resolution at a scale of 1: 200, 00O(Fig. 3, 4 and 6). The result of the analysis of AVHRR CH 4 images over the metropolitan Seoul area can be summerized as follows (1) The pattern of brightness temperature distribution in the metropolitan Seoul area shows a relatively strong temperature contrast between urban and rural areas. There is some indication of the warm brightness temperature zone characterrizing built-up area including CBD, densely populated residential district and industrial zone. The cool brightness temperature is asociaed with the major hills such as Bukhan-san, Nam-san and Kwanak-san or with the major water bodies such as Han-gang, and reservoirs. Although the influence of the river and reservoirs is obvious in the brightness temperauture, that of small-scaled land use features such as parks in the cities is not features such as parks in the cities is not apperent. (2) One can find a linerar relationshop between the brightenss temperature and air temperature for 10 major cities, where the difference between two variables is larger in big cities. Though the coefficient value is 0.82, one can estimate that factors of the heat islands can not be explained only by the size of the cities. The magnitude of the horizontal brightness temperature differences between urban and rural area is found to be greater than that of horizontal air temperature difference in Korea. (3) Also one can find the high heat island intensity in some smaller cities such as Changwon(won(Tu-r=9.0$^{\circ}$C) and Po-hang(Tu-r==7.1$^{\circ}$~)T. he industrial location quotient of Chang-won is the second in the country and Po-hang the third. (4) A comparision of the enhanced thermal infrared imageries in 1986 and 1989, with the map at a scale of 1:200, 000 for the meotropolitan Seoul area showes the extent of possible urbanization changes. In the last three years, the heat islands have been extended in area. zone characterrizing built-up area including (5) Although the overall data base is small, the data in Fig. 3 suggest that brightness tempeautre could ge utilized for the study on the heat island characteristics. Satellite observations are required to study and monitor the impact of urban heat island on the climate and environment on global scale. This type of remote sensing provides a meams of monitoring the growth of urban and suburban aeas and its impact on the environment.

• The Journal of Information Systems
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• v.24 no.2
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• pp.163-188
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• 2015

Purpose The healthcare services have drawn so much public attention, and many organizations such as schools and companies require the individuals to undergo the periodic health examination. In general, however, the mass health examination services are not managed in systematic way, and both examinees and medical staffs often experience much inconvenience while preparing, undergoing and managing the services. To address such problems, this paper aims to design the Health Examination Management System (HEMS), an integrated management system for mass health examination operations management, and implement its prototype. Design/methodology/approach First of all, HEMS enables the medical staffs to efficiently collect and manage the examination result data by supporting examination service management. Second, the users can efficiently analyze the cause-and-effect relationships among the examination items by using the visualization tool of HEMS based on the cluster heat map. Finally, the HEMS provides the operational supports for evaluating and managing the service performances. Findings The HEMS indicates that the conventional operations management approaches can be incorporated into the mass health examination services, and it is expected that the proposed system enables the examinees and the medical staffs to participate in such services in more efficient way.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.05a
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• pp.356-361
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• 1997

To investigate parametric effect on CHF and to get CHF data, experimental study has been performed with vertical round tubes under the condition of low pressure and low flow (LPLF). Test sections are made of Inconel-625 tube and have the geometry of 8 and 10 mm in diameter, and 0.5 and 1.0 m in heated length. All experiments have been conducted at the pressure of under 9 bar, the mass flux of under 250 kg/$m^2$ and the inlet subcooling of 350 and 450 kJ/kg, for stable upward flow with water as a coolant. Flow regime analysis has been performed for obtained CHF data with Mishima's flow regime map, which reveals that most of the CHF occur in the annular-mist flow regime. General parametric trends of the collected CHF data are consistent with those of previous studies. However, for the pressure effect on CHF, two different are observed; For relatively high mass flux, CHF increases with pressure and far lower mass flux, CHF decrease with pressure. Using modern data regression tool, ACE algorithm, two new CHF correlations for LPLF condition are developed based on local condition and inlet condition, respectively. The developed CHF correlations show better prediction accuracy compared with existing CHF prediction methods.

• Journal of the Korean Society of Combustion
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• v.15 no.1
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• pp.12-21
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• 2010

The main objective of this study was investigation of combustion instability characteristics in a lean partially premixed gas turbine dump combustor. Dynamic pressure transducers were located on combustor and inlet section to observe combustion pressure oscillation and difference at each measurement places. Also flame shape and $CH^*$ chemiluminescence were measured using a high speed ICCD camera. The combustor length was varied in order to have different acoustic characteristics from 800 to 1090 mm. The first section of this paper shows the stability map in model gas turbine combustor. And the effects of combustor length, mixture velocity in the mixing section and equivalence ratio were studied by the pressure perturbation and heat release oscillation. Also, the instability frequency and mode analysis were studied in last two sections. We observed two dominant instability frequencies in this study. Lower frequencies were obtained at lower equivalence ratio region and it was associated with a fundamental longitudinal mode of combustor length. Higher frequencies were observed in higher equivalence ratio conditions. It was related to secondary longitudinal mode of combustor and mixing section. In this instability characteristics, pressure oscillation of mixing section part was larger than pressure oscillation of combustor. As a result, combustion instability was strongly affected by acoustic characteristics of combustor and mixing section geometry.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.8 no.2
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• pp.240-253
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• 1996

The refrigeration cycle of automobile air-conditioners is simulated in an effort to provide a computational tool for optimum thermodynamic design. In the simulation, thermodynamic and heat transfer analysis was performed for the four major components : evaporator, condenser, compressor, and expansion valve. Effectiveness-NTU method was used for modeling both evaporator and condenser. The evaporator was divied into many subgrids and simultaneous cooling and dehumidifying analysis was performed for each grid to predict the performance accurately. Blance equations were used to model the compressor instead of using the compressor map. The performance of each component was checked against the measured data with CFC-12. Then, all the components were combined to yield the total system performance. Predicted cycle points were compared against the measured data with HFC-134a and the deviation was found to be less than 5% for all data. Finally, the system model was used to predict the performance of CFC-12 and HFC-134a for comparison. The results were very reasonable as compared to the trend deduced from the measured data.

• Mycobiology
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• v.38 no.4
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• pp.302-309
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• 2010

Formic acid is a representative carboxylic acid that inhibits bacterial cell growth, and thus it is generally considered to constitute an obstacle to the reuse of renewable biomass. In this study, Saccharomyces cerevisiae was used to elucidate changes in protein levels in response to formic acid. Fifty-seven differentially expressed proteins in response to formic acid toxicity in S. cerevisiae were identified by 1D-PAGE and nano-liquid chromatography-tandem mass spectrometry (nano-LC-MS/MS) analyses. Among the 28 proteins increased in expression, four were involved in the MAP kinase signal transduction pathway and one in the oxidative stress-induced pathway. A dramatic increase was observed in the number of ion transporters related to maintenance of acid-base balance. Regarding the 29 proteins decreased in expression, they were found to participate in transcription during cell division. Heat shock protein 70, glutathione reductase, and cytochrome c oxidase were measured by LC-MS/MS analysis. Taken together, the inhibitory action of formic acid on S. cerevisiae cells might disrupt the acidbase balance across the cell membrane and generate oxidative stress, leading to repressed cell division and death. S. cerevisiae also induced expression of ion transporters, which may be required to maintain the acid-base balance when yeast cells are exposed to high concentrations of formic acid in growth medium.

• Journal of Energy Engineering
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• v.12 no.2
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• pp.74-83
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• 2003

In the advanced nuclear power plants including APR1400, the SDVS (Safety Depressurization and Vent System) is adopted to increase the plant safety using the concept of feed-and-bleed operation. In the case of the TLOFW (Total Loss of Feedwater), the POSRV (Power Operated Safety Relief Value) located at the top of the pressurizer is expected to open due to the pressurization of the reactor coolant system and discharges steam and/or water mixture into the water pool, where the mixture is condensed. During the condensation of the mixture, thermal-hydraulic loads such as pressure and temperature variations are induced to the pool structure. For the pool structure design, such thermal-hydraulic aspects should be considered. Understanding the phenomena of the submerged steam jet condensation in a water pool is helpful for system designers to design proper pool structure, sparger, and supports etc. This paper reviews and evaluates the steam jet condensation in a water pool on the physical phenomena of the steam condensation including condensation regime map, heat transfer coefficient, steam plume, steam jet condensation load, and steam jet induced flow.