• Architectural research
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• v.17 no.4
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• pp.139-146
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• 2015

In 2007, in the city of Chongqing, the city government announced a plan to meet the basic needs of its lower-to-middle class residents, namely those of providing a shelter and urban infrastructure. In one respect, the effort to attain such goals has achieved good quantitative results; however, a more critical examination reveals that little consideration has been given to analyzing the qualitative aspects of such a policy, namely the physical and emotional effects on tenants. The results of the research in this paper have implications on the need to focus on building a 'sustainable' and 'healthy' community, with the awareness that for people in low-rent areas, sociability and community spirit are more closely related to their neighborhood contentment. Although attention to scale and type of area-planning are both important, the immediate surroundings and services are often neglected, but as we shall show they are key considerations for residents in this new type of housing. While attempting to comprehend the role of community in the quality of a neighborhood, in this research, we attempt to document the physical appearance of the problem and explore its underlying causes in order to shed more light on residents' individual evaluations of quality in their local living conditions and include the affective dimensions of such perceptions.

• Biomedical Science Letters
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• v.16 no.2
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• pp.123-126
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• 2010

Volatile organic compounds are commonly off gassed from various building materials and can induce sick building syndrome. Volatile organic compounds such as formaldehyde, xylene and toluene are known as toxic agents in immune cells. Human leukocytes, particularly, neutrophils and eosinophils play important roles in the regulation of immune responses. In this study, we investigated the toxic effects of formaldehyde, ortho-xylene (o-xylene), para-xylene (p-xylene) and toluene on the apoptosis of neutrophils and eosinophils isolated from the blood of healthy donors. Formaldehyde increased the constitutive apoptosis of neutrophils and eosinophils. o-xylene, p-xylene and toluene increased the spontaneous apoptosis of eosinophils, but not that of neutrophils. Formaldehyde increased the protein level of IL-8 in neutrophils and eosinophils, and suppressed the MCP-1 expression in neutrophils. The release of IL-6 from neutrophils was diminished by volatile organic compounds used in this study. In conclusion, formaldehyde, xylene and toluene elevate the apoptosis of neutrophils and eosinophils, and regulate the release of cytokine and chemokine in neutrophils and eosinophils. These results indicate that formaldehyde, xylene and toluene have a cytotoxicity in human neutrophils and eosinophils and may damage the modulation of immune responses.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.21 no.1
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• pp.63-70
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• 2009

The air sterilization systems are investigated experimentally in this paper. The goal is to reduce bacteria, mold and viruses in office air by using a UV sterilizer installed inside a partition panel and wall-mounted unit. These systems allow occupants to turn the system on/off and to control the incoming air speed and direction. The partition air sterilization system conditions and sterilizes the air, and then delivers the clean air into the personal task area through the partition panels, which are connected to the pressurized under-floor plenum. Room air exits through the return grills mounted on the ceiling. The wall-mounted air sterilization system sterilizes the air, and then delivers the clean air to the personal task area from the wall. In this study a full-size experimental environment is established to investigate the immunization performance of these air sterilization systems. A typical office space scale is used in this study in order to find an optimal system to achieve a sterilized healthy micro-environment. Multiple system parameters, including volume flow rate and velocity of supplied air, were regulated during the experiments. The more air contact these air sterilization systems had, the better disinfection performance. Over 90% of eradication ratios were obtained by these two air sterilization systems. The results indicate that these systems can efficiently disinfect office air contamination.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.1254-1259
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• 2009

The purpose of this study is to analyze elemental maintenance costs for educational buildings. The adapted research method selected three school buildings in Seoul as BTL projects. On the basis of the selected case, the study suggested a model to establish a system for each parts and to estimate analyzed maintenance costs through that system. According to the analysis, the study proposed a partial maintenance costs standard and analyzed proper maintenance costs. The results of this study are as follows 1) The system is divided into 8 large-groups and 24 small-groups for the analysis elemental maintenance costs. 2) The average rations followed by analysis of partial maintenance costs of the three school buildings are as followings, the total maintenance costs are analyzed 3,992 million won and each part of average rations is exterior of building 10.9%, interior of building 41.58%, electricity & fire fighting facility 14.22%, water supply & healthy facility 11.39%, heating & water supply facility 12.93%, landscape 6.3%, civil engineering works 2.69%.

• Journal of the Korean housing association
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• v.21 no.2
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• pp.101-109
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• 2010

Various environmental problems due to rapid industrialization and urbanization have worsened to such an extent that they threaten the environmental restitution of the globe and become a critical international issue. Korean government has presented the concept of green growth as a new state vision for the next 60 years and is making efforts to solve these environmental problems. Daegu Metropolitan City has faced various environmental problems including overpopulation of the city, traffic pollution, household waste accumulation and the green zone problem because of the increase of urbanization over the last few decades. As such urbanization continues, the quality of residential environments is rapidly deteriorating and the intensive use of the land leads to an increase of building area, raising the temperatures of cities. There have therefore been demands for healthy, pleasant and satisfying residential environments and for the improvement of existing residential environments, and this demand has been fully recognized by society. Nevertheless, current residential complex developments concentrate only on raising the efficiency of land use. In related laws of the past (Daegu Metropolitan City, Urban Planning Municipal Ordinance as of October 10, 2003) an attempt was made to impose a standard to segmentalize the building-to-land ratio, floor area ratio and regulations of number of floors vertically. However, these laws have now been abolished and the regulations are being eased. The purpose of this study was to analyze the characteristics of the floating wind before and after the vertical segmentation of residential areas (Daegu Metropolitan City, Urban Planning Municipal Ordinance as of October 10, 2003) by using KLAM_21, a model that enables analysis and prediction of the flow and generation of cold wind. The purpose is also to present a plan to improve the quality of residential areas when developing a building lot and redeveloping housing areas.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2009.11a
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• pp.109-112
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• 2009

Various environmental problems due to the rapid industralization and urbanization have been worsened as much as to threaten the environmental restitution of globe and become a critical international issue. Korean government presented the green growth as a new state vision for 60 years afterwards and is making efforts to solve the environmental problems. Daegu metropolitan city has faced various environmental problems including overpopulation of cities, traffic pollution, household wastes and green zone problem because of urbanization for the last decades. As such urbanism continues, the quality of residential environment is rapidly deteriorating and the intensive use of land leads to increase of building area raising the temperature of cities. Therefore there have been demands for the healthy, pleasant and satisfying residential environment and the improvement of residential environment and such recognition rises from society in full measure. Nevertheless the current residential complex concentrates only on raising the efficiency of land use. Related laws in the past(Daegu Metropolitan City, Urban Planning Municipal Ordinance as of October 10, 2003) tried to prepare a standard to segmentalize the building-to-land ratio, floor area ratio and regulations of number of floors vertically, but currently it is abolished and the regulations are becoming eased. The purpose of this study was to analyze the characteristics of the floating wind before and after the vertical segmentation of residential areas(Daegu Metropolitan City, Urban Planning Municipal Ordinance as of October 10, 2003) by using KLAM_21, a model that enables analysing and predicting the flow and generation of clod wind, and to present a plan to improve the quality of residential areas afterwards when developing building lot and re-developing housing areas.

• Health Policy and Management
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• v.17 no.4
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• pp.54-81
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• 2007

The paradigm of health promotion requests community participation and its active problem-solving. Community is conceptualized as a resource pool to be organized. Such resource is called community capacity. Community participation is a process of capacity building. Community voluntary associations are considered as valuable resource to be used for health promotion. This paper tried to identify the network structure among community voluntary associations and to infer the possibility to make such network of organizations participate in health promotion programs. Two survey data were used for this research: 1) Measurements and Evaluations of Community Capacity on Dobong-gu (N=94) 2) A development plan of health medicine service to be Healthy Gangdong-gu (N=69). The questionnaire included such variables measuring community capacity as leadership, membership, organizational resources, and inter-organizational network, etc. Both regions had the following common characteristics: 1) There were positive correlations between the organization's budget and membership. 2) Organizational types were associated with their founded years. Two regions showed the following differences: Dobong displayed the high density of community organizations, but Gangdong showed the low density. Dobong community organizations were able to be classified into three network clusters such as women & environments, youth & adolescent, and sports organizations. Each cluster of organizations favored the different type of health promotion programs. Gangdong community organizations were less developed, and not possible to be clustered. Depending upon the level of community capacity or community organizations' differentiation, the strategy of community participation could be settle down in different ways. Particularly the health agency had to pay more attention to support the growth of civil organizations.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.7071-7076
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• 2015

Epidermal growth factor receptor (EGFR) is one of the targeted molecular markers in many cancers including lung malignancies. Gefitinib and erlotinib are two available therapeutics that act as specific inhibitors of tyrosine kinase (TK) domains. We performed a case-control study with formalin-fixed paraffin-embedded tissue blocks (FFPE) from tissue biopsies of 167 non-small cell lung carcinoma (NSCLC) patients and 167 healthy controls. The tissue biopsies were studied for mutations in exons 18-21 of the EGFR gene. This study was performed using PCR followed by DNA sequencing. We identified 63 mutations in 33 men and 30 women. Mutations were detected in exon 19 (delE746-A750, delE746-T751, delL747-E749, delL747-P753, delL747-T751) in 32 patients, exon 20 (S786I, T790M) in 16, and exon 21 (L858R) in 15. No mutations were observed in exon 18. The 63 patients with EFGR mutations were considered for upfront therapy with oral tyrosine kinase inhibitor (TKI) drugs and have responded well to therapy over the last 15 months. The control patients had no mutations in any of the exons studied. The advent of EGFR TKI therapy has provided a powerful new treatment modality for patients diagnosed with NSCLC. The study emphasizes the frequency of EGFR mutations in NSCLC patients and its role as an important predictive marker for response to oral TKI in the south Indian population.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2006.11a
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• pp.212-215
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• 2006

The Beautiful rest room is simple how to think. We need to understand that excretion is important as much as eating. When we didn't have foods, eating was important in itself no matter what our lives environments. But now we want to eat in more dignified and more cultural place. Most of restaurants spend money on adjusting place for the consumes' desire. It is same way about rest room, it is time to change our rest room to place of rest and speculation over the place which we fix our natural urge. We can fix our natural urge, take a rest, and get creative ideas in more convenient, more healthy and more comfortable. It is time for us to change out thought about rest room; it is not dirty and stink place, but civilized living place like developed country. Also, we need new concept to take a triangular position about rest room is one of structure over just decorations. This research suggest new public rest room without precedent based on instance analysis about rest room inside and outside the country.

• International Journal of High-Rise Buildings
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• v.6 no.2
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• pp.187-196
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• 2017

A generation of tall buildings has been dominated by International Style with full height glazing that is often vision glass. Large glass was intended to bring the outside in, to allow a connection to the natural environment, and to promote daylighting. Yet the glass box model of architecture is now under criticism due to expense to build, thermal and visual comfort issues for occupants, large carbon footprints, danger for birds, and aesthetic concerns with lack of transparency. This paper will take a fresh look at glass, transparency, energy consumption, and human health before offering alternative paths forward.