Shin, Sunhye;Lim, Yeseo;Chung, Jayong;Park, Soyoung;Han, Sung Nim
Journal of Nutrition and Health
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v.54
no.5
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pp.435-447
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2021
Purpose: Body adiposity is negatively correlated with hepatic iron status, and Korean pine nut oil (PNO) has been reported to reduce adiposity. Therefore, we aimed to study the effects of PNO on adiposity, hepatic mineral status, and the expression of genes and proteins involved in iron absorption. Methods: Five-week-old male C57BL/6 mice were fed a control diet containing 10% kcal from PNO (PC) or soybean oil (SBO; SC), or a high-fat diet (HFD) containing 35% kcal from lard and 10% kcal from PNO (PHFD) or SBO (SHFD). Hepatic iron, copper, and zinc content; and expression of genes and proteins related to iron absorption were measured. Results: HFD-fed mice had a higher white fat mass (2-fold; p < 0.001), lower hepatic iron content (25% lower; p < 0.001), and lower hepatic Hamp (p = 0.028) and duodenal Dcytb mRNA levels (p = 0.037) compared to the control diet-fed mice. Hepatic iron status was negatively correlated with body weight (r = -0.607, p < 0.001) and white fat mass (r = -0.745, p < 0.001). Although the PHFD group gained less body weight (18% less; p < 0.05) and white fat mass (18% less; p < 0.05) than the SHFD group, the hepatic iron status impaired by the HFD feeding did not improve. The expression of hepatic and duodenal ferroportin protein was not affected by the fat amount or the oil type. PNO-fed mice had significantly lower Slc11a2 (p = 0.022) and Slc40a1 expression (p = 0.027) compared to SBO-fed mice. However, the PC group had a higher Heph expression than the SC group (p < 0.05). The hepatic copper and zinc content did not differ between the four diet groups, but hepatic copper content adjusted by body weight was significantly lower in the HFD-fed mice compared to the control diet-fed mice. Conclusion: HFD-induced obesity decreased hepatic iron storage by affecting the regulation of genes related to iron absorption; however, the 18% less white fat mass in the PHFD group was not enough to improve the iron status compared to the SHFD group. The hepatic copper and zinc status was not altered by the fat amount or the oil type.
An, Sumin;Ahn, Hyejin;Woo, Jeonghyeon;Yun, Young;Park, Yoo Kyoung
Journal of Nutrition and Health
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v.54
no.5
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pp.515-533
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2021
Purpose: A systematic review and meta-analysis of nutrition educational intervention studies was performed to assess the association between nutrition education intervention and fruit & vegetable (F&V) preferences and nutrition knowledge in preschool children. Methods: The relevant studies of nutrition education intervention and F&V preferences and nutrition knowledge published from January 2000 to June 2020 were located using PubMed, Web of Science, Cochrane Library, Research Information Sharing Service, Korean Studies Information Service System databases, and lists of references. A random-effects meta-analysis was conducted to estimate the standardized mean difference with a 95% confidence interval (CI). Subgroup analyses were performed to identify the association between nutrition education and F&V preferences and nutrition knowledge. Results: The results show that the effect sizes (ES) of F&V preferences and nutrition knowledge of preschool children were 0.31(95% CI, 0.23, 0.39), and 1.69(95% CI, 1.27, 2.12), respectively. The result of subgroup analysis, nutrition education focused on F&V (F&V preferences, ES: 0.32; nutrition knowledge, ES: 2.09) presented a slightly larger effect than general nutrition education (F&V preferences, ES: 0.26; nutrition knowledge, ES: 1.62). As for the type of exposure to F&V, direct exposure education (F&V preferences, ES: 0.40) had a greater effect than indirect exposure (F&V preferences, ES: 0.26). This meta-analysis showed that nutrition education intervention had positive effects on the F&V preferences and nutrition knowledge in preschool children. Conclusion: In conclusion, from the meta-analysis and subsequent subgroup analysis, we found that varied types of nutrition education intervention had varying effects on F&V preferences and nutrition knowledge in preschool children.
Purpose: Although numerous systematic reviews or meta-analysis have reported the hypotensive effects of garlic, the application of these results in the area of functional food is limited. This is because the trials used various garlic preparations and patients with differing hypertensive intensities. To validate the use of garlic powder as a blood pressure lowering functional food, we performed the current meta-analysis, focusing on the study of prehypertensive subjects. Methods: Literature search was carried out using various database up to July 2020, including PubMed, Cochrane, ScienceDirect and Korean studies Information Service System, and each study was screened by pre-stated inclusion/exclusion criteria. We identified nine trials that met the eligibility, of which two studies with moderate or high risk of bias were excluded. Results: Meta-analysis of the seven studies revealed that an intake of garlic powder significantly lowered the systolic blood pressure (SBP) and diastolic blood pressure (DBP) by -6.0 mmHg (95% confidence interval [CI], -11.2, -0.8; p = 0.025) and -2.7 mmHg (95% CI, -5.3, -0.1; p = 0.046), respectively. Shapes of the funnel plot for both SBP and DBP seemed symmetrical, and the Egger's regression revealed no publication bias. Moreover, duration of the intervention period was inversely associated with the pooled effects of garlic powder on SBP (p = 0.019) and DBP (p = 0.019), and this result was supported by the subgroup-analysis. The daily dose of garlic powder, baseline value of each biomarker, and subject number, did not moderate the effects on SBP and DBP. Conclusion: Results of the present meta-analysis indicate that garlic powder supplements are superior to placebo for improving the BP in prehypertensive individuals.
The purpose of this study was to derive their cognitive, psychological, and behavioral characteristics through a fusion study that analyzed the quantified results of post-homeless people participating in the housing support project after the electroencephalogram test. Participants in this study are 6 people who have lived in temporary homeless facilities or homeless living facilities and have expressed their intention to participate in the housing support project. Electroencephalogram measurements were performed using Brainmaster equipment according to the International 10-20 Law. As a result of the analysis, the study participants showed high levels of Theta wave, Beta wave, and High Beta wave, which show the peculiarity of the emotional aspect, which is a result of showing emotional characteristics such as anger, anxiety, and insomnia in the emotional aspect. Therefore, it is suggested that they provide stress management, counseling, and physical health management services in order to maintain a stable residential life in the community in the future. The results of this study presented a quantitative basis for the cognitive, psychological, and behavioral characteristics of homeless people, and suggests a support system necessary for them to maintain self-reliance in communities in the future.
Musculoskeletal disorders affect workers' safety in most industries, and forest operations are classified as a musculoskeletal burden according to the Occupational Safety and Health Act in South Korea. In particular, felling and delimbing operations are mainly conducted by manpower, and then, it is necessary to evaluate ergonomic risk assessment for safety of felling and delimbing workers. Three ergonomic risk assessment methods, such as Ovako Working posture Analysis System (OWAS), Rapid Upper Limb Assessment (RULA), and Rapid Entire Body Assessment (REBA), are available for assessing exposure to risk factors associated with timber harvesting operations. Here, three ergonomic risk assessment methods were applied to examine ergonomic risk assessments in chainsaw felling and delimbing operations. Additionally, exposure to risk factors in each method was analyzed to propose an optimal working posture in felling and delimbing operations. The risk levels of these operations were evaluated to be highest in the RULA method, followed by the OWAS and REBA methods, and most of the exposed working postures were examined with a low-risk level of two and three without requiring any immediate working posture changes. However, two significant working postures, including the bending posture of the waist and leg in felling operation and standing posture on the fallen trees in delimbing operation, were assessed as the high-risk level and needed immediate working posture changes. Low-risk work levels were examined in the squatting posture for felling operation and the straightened posture of the waist and leg for delimbing operation. Moreover, the slope in felling operation and the tree height in delimbing operation significantly affected risk level assessment of working posture. Therefore, our study supports that felling and delimbing workers must operate with low-risk working postures for safety.
Proceedings of the Plant Resources Society of Korea Conference
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2019.10a
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pp.64-64
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2019
Screening and identification of genetic resources based on their phytoconstituents and morphological characters potentially provide baseline data for researchers, breeders, and nutraceutical companies who wish to formulate a nutrient-dense diet and health beneficial supplement. Thus, we evaluated the amount of total phenolic content and major phenolic compounds; examined if phenolic compounds could be used as distinguishing factors for perilla genetic resources; and investigated the relation between some quantitative and qualitative morphological characters with the contents of phenolic compounds in 360 accessions obtained from National Agrobiodiversity Center gene bank, Jeonju, Korea. Total phenolic content (TPC) was estimated using Folin-Ciocalteu colorimetric assay. Individual phenolic compounds were determined using an Ultra-High Performance Liquid Chromatography system equipped with Photodiode Array detector. Considerable variations were observed in TPC (7.99 to 117.47 mg GAE/g DE), rosmarinic acid (RA) (ND to 19.19 mg/g DE), caffeic acid (CA) (ND to 0.72 mg/g DE), apigenin-7-O-diglucuronide (ADG) (ND to 1.24 mg luteolin equivalent (LUE)/g DE), scutellarein-7-O-glucuronide (SG) (ND to 4.32 mg LUE/g DE), and apigenin-7-O-glucuronide (AG) (ND to 1.60 mg LUE/g DE). RA was the most dominant phenolic compound in most accessions (95.3%) followed by SG. The adaxial leaf color was light green, green and dark green in 13.8%, 65.0%, and 21.1 % of the accessions, respectively. 78.8% of the accessions had light green color at the abaxial side with the remaining being described as green. Most of the accessions (96.9%) were cordate shape, the remaining being eclipse. Intensities of green pigment at abaxial and adaxial leaf surfaces were correlated with contents of individual phenolic compounds and TPC whereas leaf length and width had no correlation with TPC, CA and RA, and negatively correlated with ADG, AG, and SG. Leaf shape was not related with content of phenolic compounds, color of leaves, or the length or width of leaves. Accessions IT57426, IT157434, IT267710, and IT267712 which contained relatively high contents of TPC and major phenolic compounds (RA and SG) could be used for further research in breeding and bioassay test. Our study result showed the contents of total phenolics and individual phenolic compounds along with the morphological characters could be useful distinguishing factors for perilla genetic resources.
Fibromyalgia is a disorder characterized by the core symptom of chronic widespread pain, along with fatigue, sleep disturbances, mood changes, and cognitive difficulties. The etiology of fibromyalgia involves a combination of biological factors, such as genetic vulnerability, alterations in pain processing and stress response system ; psychological factors, such as anxiety, depression, anger, and perceived stress ; environmental factors, such as infections, febrile diseases, and trauma. Central sensitization, which is amplified in the process of sensory stimulation, has been emphasized as a key etiological factor, as supported by enhanced wind-up, delayed aftersensation, decreased nociceptive flexion reflex threshold and functional imaging studies. Several guidelines recommend that a multimodal approach be used to treat fibromyalgia, including both pharmacological and non-pharmacological treatments, tailored to each individual, and that clinicians should provide an intellectual framework through sufficient education and emphasis on the importance of self-management. The prevalence of mood disorders, anxiety disorders, and other psychiatric problems is 7-9 times higher in patients with fibromyalgia than in the general population ; moreover, the association between fibromyalgia and certain psychopathologies or sleep problems has also been suggested. Since psychiatric problems, with shared vulnerabilities and risk factors, interact with fibromyalgia bidirectionally and also affect the disease course, an integrated management approach is needed to determine the risk of comorbidities.
The purpose of this study is to analyze various issues that may arise from the recent deregulation of telemedicine implemented by the government, propose initiative preparations for the implementation of telemedicine policies, and suggest implications for the basic conditions and direction of the deregulation of telemedicine. Recently, deregulation policy cases in telemedicine include that designation of a special zone for regulatory freedom in Gangwon Province, allowing physician-patient telemedicine and telephone counseling and prescription cases in the COVID-19 crisis. There are four main issues that could arise with the deregulation of telemedicine: safety, effectiveness, differences in access to health care and the economic industry, and legal responsibility. As a initiative preparation, this study proposed a pilot project for telemedicine and enhanced support for face-to-face care complementary tools, vitalizing remote co-operation, policy model that do not disrupt the medical delivery system, and legal maintenance. In conclusion, as a suggestion of basic premise and direction in the implementation of telemedicine deregulation, the implementation of initiative measures to address issues concerning telemedicine, the review and regulation of conditions to be considered in the implementation of telemedicine, and the establishment of a close communication and cooperative sturcture with medical providers.
Journal of the Korea Academia-Industrial cooperation Society
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v.22
no.6
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pp.215-225
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2021
The purpose of this study was to empirically verify the correlation between the characteristics of safety officers and managers handling disaster and safety management, competence, and performance among disaster and safety work-level officers in medium-sized companies in South Korea. For this study, the researcher surveyed 509 disaster and safety management officers of various companies and analyzed the resultant data. The results of the analysis showed that, first, the characteristics of the safety officers handling the disaster and safety management systems had a significantly positive impact on performance. Second, the characteristics of the safety officers handling the disaster management systems had a significantly positive impact on competence. Third, the disaster and safety management competence of the safety officers had a significantly positive impact on performance. Fourth, in the relationship between the characteristics of the safety officers handling the disaster and safety management systems of businesses and their performance, the competence of the safety officers had a mediating effect.
The purpose of this study was to research the effects of socio-demographic factors and values in each group on satisfaction with life by categorizing the activity types of the elderly into volunteer work and economic activities. The subjects of this study were 60 years an old higher. The questionnaires were categorized depending on activity types and collected. The voluntary work group consisted of 201 people (76 males, 36.8% and 125 females, 62.2%), The economic activity group consisted of 219 people (127 males, 58.0% and 92 females, 42.0%). The SPSS 14.0 Windows program was used to analyze data. Frequency, average, standard deviation, factor analysis, Pearson correlation coefficient, t-test, One-Way ANOVA analysis, and hierarchical multiple linear regression were analyzed. The major findings of this study indicate that the elderly in the voluntary work group have a high collectivism value, higher income earned by performing economic activities, and good cognitive health affected by a high satisfaction with life. From these research results, it was proved that a collectivism value is a common factor that affects satisfaction with life in both of the economic activity group. Those who were older had a traditional collectivism value. The voluntary work group showed a stronger collectivism value and higher satisfaction with life than the economic activity group. Thus, the diverse types of voluntary work should be developed and a systematic system should be established as methods for improving quality of life and satisfaction.
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