• International Journal of Ocean Engineering and Technology Speciallssue:Selected Papers
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• v.4 no.1
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• pp.51-55
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• 2001

The characteristics of elastic waves emanating from crack initiation in 2024 and 5052 aluminum alloys subject to static and fatigue loading are investigated through laboratory experiments. The objective of the study is to determine difference in the properties of the signals generated from static and fatigue tests and also to examine if the sources of the waves could be identified from the temporal and spectral characteristics of the acoustic emission (AE) waveforms. The signals are recoded using non-resonant, flat, broadband transducers attached to the surface of the alloy specimens. The time dependence and power spectra of the signals recorded during the tests were examined and classified according to their special features. Three distinct types of signals were observed. The waveforms and their power spectra were found to be dependent on the material and the type of fracture associated with the signals. Analysis of the waveforms indicated that some signals could be attributed to plastic deformation associated with static tests. The potential application of the approach in health monitoring of aging aircraft structures using a network of surface mounted broadband sensors is discussed.

• Structural Engineering and Mechanics
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• v.54 no.2
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• pp.199-219
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• 2015

This paper presents the non-destructive evaluation of a high-speed railway bridge using train-induced strain responses. Based on the train-track-bridge interaction analysis, the strain responses of a high-speed railway bridge under moving trains with different operation status could be calculated. The train induced strain responses could be divided into two parts: the force vibration stage and the free vibration stage. The strain-displacement relationship is analysed and used for deriving critical displacements from theoretical stain measurements at a forced vibration stage. The derived displacements would be suitable for the condition assessment of the bridge through design specifications defined indexes and would show certain limits to the practical application. Thus, the damage identification of high-speed railways, such as the stiffness degradation location, needs to be done by comparing the measured strain response under moving trains in different states because the vehicle types of high-speed railway are relatively clear and definite. The monitored strain responses at the free vibration stage, after trains pass through the bridge, would be used for identifying the strain modes. The relationship between and the degradation degree and the strain mode shapes shows certain rules for the widely used simply supported beam bridges. The numerical simulation proves simple and effective for the proposed method to locate and quantify the stiffness degradation.

• Earthquakes and Structures
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• v.18 no.3
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• pp.321-335
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• 2020

The aim of the present contribution is to consider and underline the essential interactions among the historical knowledge, the seismic vulnerability assessment, the investigation experimental tools, the preservation of the architectural quality and the strengthening design in regard to architectural heritage conservation. These topics are argued in relation to Palazzo Murena in Perugia, designed in the eighteenth century by the famous Architect Luigi Vanvitelli, and currently headquarters of the city's University. Based on the surveys and the visual inspections, a preliminary a priori global analysis has been performed by means of the FME method. The obtained results permitted to plan an experimental tests campaign inclusive of structural health monitoring. The new achieved "knowledge" of the building allowed to refine the seismic safety assessment. In particular it was highlighted that the "mezzanine floor" can be a vulnerable element of the building with the collapse of its masonry walls. Preserving the architectural characteristics, a local reinforcement intervention is proposed for the above-mentioned level; this consists of the application of plaster with FRCM, assuring an adequate strength, without burden the masonry structure with additional weight, and therefore a decreasing of the seismic vulnerability. The necessity to consider, in this ongoing research, other local mechanisms is highlighted in the unfolding of the last part of work.

• Journal of Information Technology Services
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• v.15 no.1
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• pp.39-66
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• 2016

There is growing evidence that professional work is changing as a result of the application of information technology (IT). However, the impact of information technology on professional work has produced mixed results. Our paper considers the source of these mixed results through a greater analytical attention paid to the nature of professional work. Defined as work involving expertise expressed through abstract and formalized knowledge as well as extensive working knowledge, the professional work logic assumes the greatest autonomy and discretion for workers in collectively controlling work characteristics-division of labor and its permanence, control over education, and control over new entrants and the monitoring and disciplining of existing members. The impact of IT on professional work will be difficult to control and predict without considering the assumptions and tensions within and across the three major types of work logics (Professional, Market and Bureaucratic). Using healthcare as an example, the paper provides various propositions for researching the initiation and effects of ICT design through these three work logics. These propositions illustrate the active role that IS researchers can take in researching an important economic and work-related topic, professional work, and in understanding how ICT affects work-related expertise.

• Clinical and Experimental Pediatrics
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• v.60 no.4
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• pp.99-105
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• 2017

Food allergy (FA) is a serious health problem, and severe FA such as food-induced anaphylaxis can often be life threatening. The incidence of FA has been increasing especially in children. They usually develop early in life and affect up to 10% of children. The 2 most common food allergens worldwide are milk and eggs, while the third one varies depending on the countries: peanuts in the United States and Switzerland, wheat in Germany and Japan, tree nuts in Spain, sesame in Israel, and walnuts in Korea. These common food allergens are different and difficult to identify because of differing study methodologies, population, geography, age, and dietary exposure patterns. The current management of FA relies on the strict avoidance of culprit allergens, the prompt treatment of allergic reactions, including epinephrine use for food-induced anaphylaxis, monitoring, and education to prevent further reactions. Newer approaches for tolerance induction to FA and FA immunotherapy have been under investigation but are not yet ready for real-world application. Thus, consistent and systematic education of patients, caregivers, and food-handling people is of primary importance for the management and prevention of FA reactions. This review assesses and compares IgE-mediated FA in children in Korea and other countries, with a focus on summarizing the prevalence, common triggers, and management of FA.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.10a
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• pp.505-510
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• 2002

We have focused on the development of a fiber optic BOTDA (Brillouin Optical Time Domain Analysis) sensor system in order to measure temperature distributed on large structures. Also, we present a feasibility study of the fiber optic sensor to monitor the distributed temperature on a building construction. A fiber optic BOTDA sensor system, which has a capability of measuring the temperature distribution, attempted over several kilometers of long fiber paths. This simple fiber optic sensor system employs a laser diode and two electro-optic modulators. The optical fiber of the length of 1400 m was installed on the surfaces of the building. The change of the distributed temperature on the building construction was well measured by this fiber optic sensor. The temperature changed normally up to 4℃ through one day.

• Environmental Analysis Health and Toxicology
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• v.20 no.1
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• pp.1-11
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• 2005

환경오염의 조기 경보 시스템으로 생체지표를 이용한 생태독성 모니터링이 최근 널리 연구되고 있다. 환경내의 생물종에서 측정한 생체지표를 이용한 환경 모니터링은 생태계 수준의 영향에 대한 예측 정보를 제공해 줄 수도 있다. 이를 위해서는 생체지표와 개체군 수준에서의 반응과의 인과관계가 밝혀져야 한다. 오염물질에 대한 생체의 반응은 분자, 세포, 생화학, 생리적, 개체, 개체군, 군집 수준에서 나타나게 되며, 이러한 각 단계별 반응은 반응 시간의 규모와 독성학적, 생태적 관련성에 따라 구분 지어 볼 수 있다. 각 개별 수준에서의 반응을 종합하면 오염물질에 노출된 생체의 전제적인 영향을 이해할 수 있으며, 이러한 이해를 바탕으로 개체군에서 나타나는 영향에 대한 인과관계를 추론할 수 있다. 생체지표와 개체군 수준의 반응과의 인과관계 정립은 효율적인 환경오염 예방기능 수행에 필수적인 과정이며, 다단계 생체 지표는 각 단계별 반응의 인과관계를 밝히기 위해 가장 적절한 접근 방법이다. 수서 무척추 생물인 Chironomus의 유충은 이러한 다단계 바이오마커 연구에 매우 적절한 생물학적 모델이다. 이 논문의 첫 번째 부분은 생체지표를 이용한 환경 모니터링을, 두 번째 부분은 Chironomus의 유충에서 생체지표의 적용에 대해서 다룬다.

• 한국균학회소식:학술대회논문집
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• 2016.05a
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• pp.35-35
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• 2016

A mycotoxin is a toxic secondary metabolite produced by organisms of the fungus kingdom, commonly known as molds and has been widely contaminated in agricultural products such as grains and cereals. Many methods including high performance liquid chromatography (HPLC) and gas chromatography (GC) have already been proposed and reviewed for mycotoxins. These methods are either expensive or time-consuming due to the complication of sample preparation and pre-concentration before determination. In addition, both methods are unsuitable for the routine screening of large sample numbers. A biosensor is a fictive analytical device that combines a biological component with a physicochemical detector for the detection of an analyte. Biosensors represent a rapidly expanding field, at the present time, with an estimated 60% annual growth rate; the major impetus coming from the health-care industry but with some pressure from other areas, such as food safety and environmental monitoring. Antibodies and aptamers are bioreceptors which have been used in the development of biosensors. There are many kinds of antibodies and aptamers specific to mycotoxin, and antibody (or aptamer)-based biosensors have been successfully developed for the detection of mycotoxin. The biosensors permit the rapid, sensitive, simple, and on-site detection of a range of mycotoxins and can be an alternative method to traditional methods such as HPLC and GC. This presentation provides the development trends of biosensors to mycotoxins and their application to food and agricultural products.

• Smart Structures and Systems
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• v.20 no.6
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• pp.669-682
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• 2017

The normalised version of bispectrum, the so-called bicoherence, has often proved a reliable method of damage detection on engineering applications. Indeed, higher-order spectral analysis (HOSA) has the advantage of being able to detect non-linearity in the structural dynamic response while being insensitive to ambient vibrations. Skewness in the response may be easily spotted and related to damage conditions, as the majority of common faults and cracks shows bilinear effects. The present study tries to extend the application of HOSA to damage localisation, resorting to a neural network based classification algorithm. In order to validate the approach, a non-linear finite element model of a 4-meters-long cantilever beam has been built. This model could be seen as a first generic concept of more complex structural systems, such as aircraft wings, wind turbine blades, etc. The main aim of the study is to train a Neural Network (NN) able to classify different damage locations, when fed with bispectra. These are computed using the dynamic response of the FE nonlinear model to random noise excitation.

• Genomics & Informatics
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• v.11 no.4
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• pp.174-179
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• 2013

The large amount of data on cancer genome research has contributed to our understanding of cancer biology. Indeed, the genomics approach has a strong advantage for analyzing multi-factorial and complicated problems, such as cancer. It is time to think about the actual usage of cancer genomics in the clinical field. The clinical cancer field has lots of unmet needs in the management of cancer patients, which has been defined in the pre-genomic era. Unmet clinical needs are not well known to bioinformaticians and even non-clinician cancer scientists. A personalized approach in the clinical field will bring potential additional challenges to cancer genomics, because most data to now have been population-based rather than individualbased. We can maximize the use of cancer genomics in the clinical field if cancer scientists, bioinformaticians, and clinicians think and work together in solving unmet clinical needs. In this review, we present one imaginary case of a cancer patient, with which we can think about unmet clinical needs to solve with cancer genomics in the diagnosis, prediction of prognosis, monitoring the status of cancer, and personalized treatment decision.