• Environmental Analysis Health and Toxicology
• /
• v.20 no.2 s.49
• /
• pp.143-151
• /
• 2005

Exposure of skin to UV-B radiation can cause inflammatory response and immunosuppression. It has been reported that Korean Red Ginseng (KRG) has several pharmacological and physiological effects such as antioxidant, anticancer and improving immune function. In this study, we investigated that topical KRG and KRG + EGb 761 (Ginkgo biloba extract) combination prevented UV-B induced inflammation and inhibition of contact hypersensitivity response. Topical application of KRG, f days prior to or 5 days after exposure to 1MED and 2MED of UV-B, reduced skin thickness compared to non -treated group and resulted in protection against immunosuppression. However, KRG+EGb 761 combination has a little protection against the only 1MED UV-B. In conclusion. Topical application of KRG was more effective than combination in protection against UV-B induced inflammation and immune suppression. Also, we suggest that KRG can provide protection from inflammation and immunosuppression by UV-B radiation.

• Journal of Environmental Health Sciences
• /
• v.32 no.5 s.92
• /
• pp.492-498
• /
• 2006

Ultraviolet(UV) radiation causes a variety of biological effects on the skin, including inflammation, pigmentation, photoaging and cancer. Free radicals are involved in inflammatory skin reactions induced by UVB radiation. In this study, we investigated the effects of antioxidants(Tea, Korean red ginseng, Ginkgo biloba extract) on UVB-induced skin damage. Tea, KRG and EGb 761 were topically treated to dorsal skin of ICR mouse. The mice were also treated soon after IMED ($1.4KJ/m^{2}$) of UVB irradiation. Skin pigmentation of irradiated mouse was observed by a chromameter after 2 weeks. Topical application of Tea, KRG and EGb 761 for 2 weeks decreased skin pigmentation compared to DVB control group(p<.05). Tea, KRG and EGb 761 also reduced UVB-induced infiltration of inflammatory cells. These results showed that Tea, KRG and EGb 761 as a topical application may have preventive effect against UVB-induced skin damage.

• Korea Journal of Hospital Management
• /
• v.25 no.1
• /
• pp.1-12
• /
• 2020

Purposes: The aim of this study is to evaluate whether the contents of hospital reservation and reception applications(apps) are qualitatively useful in meeting the needs of medical consumers and improving hospital accessibility and convenience. Methodology: (1) identify consumer needs through social data web mining, (2) describe the status of key contents of mobile apps to improve accessibility and convenience of care, and (3) verify the quality of apps through validated tools Finding: The contents of 'mobile reservation function' and 'waiting time information provision' that can contribute to reduction of delay time of care and efficiency of desk work were supported, but the level of utilization was insufficient. The quality level of the app, including the level of consumers' needs, has shown a wide gap between the apps. Implications: The recent development of mobile apps for hospital accessibility and consumer needs has shown a wide gap in the quality of apps, including information and aesthetic. Therefore, it is necessary to develop apps based on user interface(UI), user experience(UX) based designs that can promote the usefulness and convenience of apps while monitoring needs of consumers continuously.

• Nuclear Engineering and Technology
• /
• v.52 no.10
• /
• pp.2262-2273
• /
• 2020

Digital twin technology can provide significant value for the prognostics and health management (PHM) of critical plant components by improving insight into system design and operating conditions. Digital twinning of systems can be utilized for anomaly detection, diagnosis and the estimation of the system's remaining useful life in order to optimize operations and maintenance processes in a nuclear plant. In this regard, a conceptual framework for the application of digital twin technology for the prognosis of Control Element Drive Mechanism (CEDM), and a data-driven approach to anomaly detection using coil current profile are presented in this study. Health management of plant components can capitalize on the data and signals that are already recorded as part of the monitored parameters of the plant's instrumentation and control systems. This work is focused on the development of machine learning algorithm and workflow for the analysis of the CEDM using the recorded coil current data. The workflow involves features extraction from the coil-current profile and consequently performing both clustering and classification algorithms. This approach provides an opportunity for health monitoring in support of condition-based predictive maintenance optimization and in the development of the CEDM digital twin model for improved plant safety and availability.

• Women's Health Nursing
• /
• v.24 no.1
• /
• pp.1-13
• /
• 2018

Purpose: To develop educational material about nutrition during antepartum period for women pregnant with twins by using smartphone applications. Methods: A series of steps according to ADDIE model, including Analysis, Design, Development, Implementation, and Evaluation were used to develop smartphone application of antepartum nutrition care for women pregnant with twins. Results: Based on experts' evaluation, the average score was $4.6{\pm}0.39$ in total. Content score was $4.7{\pm}0.40$. Interface design score was $4.5{\pm}0.55$. Content score was higher than interface design score. User evaluation was conducted in the form of interview. Results of interviews revealed that users generally responded positively to the accuracy, understanding, and objectivity for content items of the smartphone app. As for the evaluation of consistency for the evaluation item of interface design, users answered "ordinary" or "generally yes". For design suitability and accuracy of vocabulary, they answered 'generally suitable'. Conclusion: The smartphone app developed through this study is expected to aid antepartum care for women pregnant with twins. It will also contribute to health promotion of both pregnant women and twin fetus.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2014.10a
• /
• pp.699-700
• /
• 2014

The use of Radio Frequency Identification technology (RFID) in medical context enables not only drug identification, but also a rapid and precise identification of patients, physicians, nurses or any other healthcare giver. The combination of RFID tag identification with structured and secured Internet of Things (IoT) solutions enables ubiquitous and easy access to medical related records, while providing control and security to all interactions. This paper defines a basic security architecture, easily deployable on mobile platforms, which would allow to establish and manage a medication prescription service in mobility context making use of electronic Personal Health Records. This security architecture is aimed to be used with a mobile e-health application (m-health) through a simple and intuitive interface, supported by RFID technology. This architecture, able to support secured and authenticated interactions, will enable an easy deployment of m-health applications. The special case of drug administration and ubiquitous medication control system, along with the corresponding Internet of Things context, is presented.

• Animal Bioscience
• /
• v.36 no.5
• /
• pp.679-691
• /
• 2023

The fat deposition is an important factor affecting chicken meat quality, which is closely related to lipid metabolism of chickens. Therefore, it is important to regulate the lipid metabolism of chickens to improve the chicken meat quality. Plant extracts have special regulatory effects on animal's growth and health and have been widely used in chicken breeding. Some plant extracts have been reported to have functions of changing the fatty acid composition, reducing abdominal fat percentage, and enhancing the intramuscular fat content of chickens by improving the antioxidant capacity, regulating the expression of genes, enzymes, and signaling pathways related to lipid metabolism, modulating intestinal microbiota, affecting hormones level, and regulating DNA methylation. This paper reviewed the application and mechanism of plant extracts on regulating lipid metabolism of chickens to provide a reference for the further application of plant extracts in chicken breeding.

• Anxiety and mood
• /
• v.9 no.2
• /
• pp.128-134
• /
• 2013

Objective : As treatments for breast cancer require long period of time, the patients need continuous monitoring and management of their health related quality of life. The purpose of this preliminary study is to explore the utility of monitoring quality of life using a mobile phone based application, which was developed to enable the patients to report daily quality of life more efficiently. Methods : Department of psychiatry, breast cancer center and U-health team of Asan Medical Center collaborated in developing a mobile application titled 'DugunDugun'. Through the application, patients with breast cancer receiving neo-adjuvant chemotherapy could report on various questions about their daily quality of life. We extracted and explored the daily basis of the data of sleep duration, number of awake, sleep satisfaction, mood and anxiety from nine patients who reported on the questionnaire for more than a month. Results : The longitudinal data collected using our mobile application well represented the characteristics of individual sleep patterns and daily emotional changes. Most of the patients showed high daily variations in the scores of their quality of life while their averaged scores were similar among patients. The patient with highest daily variations in the subjective sleep quality and daily emotional change had highest score corresponding to moderate depression in Beck Depression Inventory (BDI). Conclusion : The results suggest that mobile application could be a useful tool for monitoring and collecting the daily quality of life in the patients with breast cancer. We expect that mobile application could facilitate early detection and proper intervention for the cancer patients at psychological crisis.

• Food Science and Biotechnology
• /
• v.17 no.1
• /
• pp.26-30
• /
• 2008

This study was conducted to identify the effect of chilling temperature (-3 and $6^{\circ}C$) and aging (1- and 7-day) on objective meat quality, collagen solubility, and free amino acids in pork (longissimus muscle of Yorkshire). Warner-Bratzler (WB)-shear force indicated that variation in chilling temperature had no detectable effect on meat tenderness and tenderization during the 7-day aging period. Among the 13 detected free amino acids, only 3 amino acids (histidine, valine, leucine) were significantly affected by the temperature treatment (p<0.05). Collagen solubility was significantly increased at $6^{\circ}C$ treatment (p<0.05). There was a significant linear relationship (r=0.67, p<0.05) between changes in free amino acids and WB-shear force during the 7-day aging period. These results confirmed that chilling conditions had significantly affected collagen solubility, and meat tenderization occurred in direct proportion to an increase in free amino acids.

• Wind and Structures
• /
• v.21 no.6
• /
• pp.693-707
• /
• 2015

The efficiency of wind turbines (WT) is primarily reflected in their ability to generate electricity at any time. Downtimes of WTs due to "conventional" inspections are cost-intensive and undesirable for investors. For this reason, there is a need for structural health monitoring (SHM) systems, to enable service and maintenance on demand and to increase the inspection intervals. In general, monitoring increases the cost effectiveness of WTs. This publication concentrates on the application of two vibration-based SHM algorithms for stability and structural change monitoring of offshore WTs. Only data driven, output-only algorithms based on stochastic subspace identification (SSI) in time domain are considered. The centerpiece of this paper deals with the rough mathematical description of the dynamic behavior of offshore WTs and with the basic presentation of stochastic subspace-based algorithms and their application to these structures. Due to the early stage of the industrial application of SHM on offshore WT on the one side and the required confidentiality to the plant manufacturer and operator on the other side, up to now it is not possible to analyze different isolated structural damages resp. changes in a systematic manner, directly by means of in-situ measurement and to make these "acknowledgements" publicly available. For this reason, the sensitivity of the methods for monitoring purposes are demonstrated through their application on long time measurements from a 1:10 large scale test rig of an offshore WT under different conditions: undamaged, different levels of loosened bolt connections between tower parts, different levels of fouling, scouring and structure inclination. The limitation and further requirements for the approaches and their applicability on real foundations are discussed along the paper.