• Journal of Nutrition and Health
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• 제36권7호
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• pp.736-742
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• 2003

Soybeans have been a major protein source for many centuries in Korea. Soybeans contain phytochemicals which are isoflavones, biochemically active component. Isoflavone is a kind of phytoestrogen, structurally and functionally similar to estrogen. It has been reported that the breast milk and blood of breast feeding mothers who consume soy products contain isoflavones. This study was conducted to investigate the effects of soy milk supplement on the isoflavones (daidzein, genistein) concentration of breast milk, plasma and urine from breast feeding woman. Seventeen healthy women who delivered at Kyung Hee Medical Center were recruited. For the first 2 weeks after delivery, seventeen women ingested 400 ml (isoflavone 43.2 mg) of soy milk on the given time starting from the day of giving birth. For the next 2 weeks, soy milk ingestion was withdrawn. Dietary intake and anthropometric data were checked and breast milk, blood, and 24 hr urine samples were collected on the day of giving birth, the 14th (the last day of the supplement phase) and 28th (the last day of the withdrawal phase) day, respectively. HPLC analysis was used to measure the concentration of isoflavones. Dietary intakes of the subjects were inadequate for the Korean RDA regardless of soy milk supplementation. Especially, intakes of vit A, calcium, and iron were very low. The Anthropometric data such as LBM, TBW, PIBW, BMI checked on the day of 14th decreased and maintained their levels by the 28th day. Daidzein concentration in breast milk was not affected by soy milk supplementation. However, genistein concentration decreased by the 28th day (14th day: 0.89 $\pm$ 0.10 $\mu$g/ml, 28th day : 0.48 $\pm$ 0.07 $\mu$g/ml) (p < 0.05). Plasma daidzein and genistein concentrations were not changed by the 14th day and decreased by the 28th day (14th day: 49.64 $\pm$ 3.30 ng/ml, 26.72 $\pm$ 2.90 ng/ml, 28th day: 38.30 $\pm$ 4.40 ng/ml, 6.51 $\pm$ 0.50 ng/ml, respectively) (p < 0.05). Twenty four hour urine concentrations of daidzein and genistein significantly increased by the 14th day and decreased by the 28th day (14th day: 5.80 :t 0.3 mg/d, 4.17 $\pm$ 0.2 mg/d, 28th day: 6.72 $\pm$ 0.4 mg/d, 5.09 $\pm$ 0.5 mg/d, respectively) (p < 0.001). The rate of urinary recovery of daidzein was greater than that of genistein. The results of this study indicate that the supplement of dietary soy milk to the lactating women elevates the contents of isoflavone in the breast milk.

• Clinical and Experimental Reproductive Medicine
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• 제25권2호
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• pp.115-122
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• 1998

The maintenance of a viable pregnancy has long been viewed as an immunological paradox. The deveolping embryo and trophoblast are immunologically foreign to the maternal immune system due to their maternally inherited genes products and tissue-specific differentiation antigens (Hill & Anderson, 1988). Therefore, speculation has arisen that spontaneous abortion may be caused by impaired maternal immune tolerance to the semiallogenic conceptus (Hill, 1990). Loss of recall antigen has been reported in immunosuppressed transplant recipients and is associated with graft survival (Muluk et al., 1991; Schulik et al., 1994). Progesterone $(10^{-5}M)$ has immunosuppressive capabilities (Szekeres-Bartho et al., 1985). Previous study showed that fertile women, but not women with unexplained recurrent abortion (URA), lose their immune response to recall antigens when pregnant (Bermas & Hill, 1997). Therefore, we hypothesized that immunosuppressive doses of progesterone may affect proliferative response of lymphocytes to trophoblast antigen and alloantigen. Proliferative responses using $^3H$-thymidine ($^3H$-TdR) incorporation of peripheral blood mononuclear cells (PBMCs) to the irradiated allogeneic periperal blood mononuclear cells as alloantigen, trophoblast extract and Flu as recall antigen, and PHA as mitogen were serially checked in 9 women who had experienced unexplained recurrent miscarriage. Progesterone vaginal suppositories (100mg b.i.d; Utrogestan, Organon) beginning 3 days after ovulation were given to 9 women with unexplained RSA who had prior evidence of Th1 immunity to trophoblast. We checked proliferation responses to conception cycle before and after progesterone supplementation once a week through the first 7 weeks of pregnancy. All patients of alloantigen and PHA had a positive proliferation response that occmed in the baseline phase. But 4 out of 9 patients (44.4%) of trophoblast antigen and Flu antigen had a positive proliferative response. The suppression of proliferation response to each antigen were started after proliferative phase and during pregnancy cycles. Our data demonstrated that since in vivo progesterone treated PBMCs suppressed more T-lymphocyte activation and $^3H$-TdR incorporation compare to PBMCs, which are not influenced by progesterone. This data suggested that it might be influenced by immunosuppressive effect of progesterone. In conclusion, progesterone may play an important immunological role in regulating local immune response in the fetal-placental unit. Furthermore, in the 9 women given progesterone during a conception cycle, Only two (22%) repeat pregnancy losses occured in these 9 women despite loss of antigen responsiveness (one chemical pregnancy loss and one loss at 8 weeks of growth which was karyotyped as a Trisomy 4). These finding suggested that pregnancy loss due to fetal aneuploidy is not associated with immunological phenomena.

• 치위생과학회지
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• 제3권1호
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• pp.5-10
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• 2003

치과의료 종사자의 연봉제 도입에 대한 의식 고찰을 통하여 연봉제에 대한 바람직한 방향 설정과 활성화 방안을 모색하는 계기를 마련하고자 문헌과 자료를 조사하고, 전국 치과 병, 의원에 종사는 구성원 95명을 대상으로 2002년 4월부터 8월까지 약 5개월 동안 설문조사를 실시하여 분석한 결과 다음과 같은 결론을 얻었다. 1. 근무하는 병원의 형태에 따라 연봉제에 대한 인식을 살펴본 결과, 치과병원의 종사자가 치과의원의 종사자보다 연봉제 실시로 인한 경영참여의식(p<.001)과 업무생산성의 향상(p<.01), 목표달성에 대한 사명감(p<.01), 장래에 대한 불안감(p<.05)에 대해 더 높은 인식을 보였다. 2. 연봉제에 대한 치과의사와 치과위생사의 인식을 살펴본 결과, 치과의사가 치과위생사보다 연봉제 실시로 인한 성과평가의 공정성(p<.01)과 능력발휘 풍토변화(p<.01), 업무생산성의 향상(p<.001), 목표달성에 대한 사명감(p<.001), 그리고 연봉제에 대해 높은 인식(p<.01)을 보이고 있음을 알 수 있다. 3. 근무경력에 따라 연봉제에 대한 인식을 살펴본 결과, 근무경력이 오래될수록 업무의 엄격성 강화정도(p<.05)와 단기 업적주의 치중 가능성(p<.05)에 대해 높은 인식을 보였으며, 3~5년 종사자가 다른 종사자보다 근무시간의 변화(p<.01)에 대해 높은 인식을 보였고, 2년 이하의 종사자가 연봉제에 대해 가장 높은 인식(p<.05)을 보이고 있음을 알 수 있다. 4. 연봉제가 성과를 거두기 위한 전제조건으로 평가결과의 공정성이 전제되어야 한다고 인식하는 치과의료 종사자가 31.6%로 가장 많았으며, 다음으로 노사 상호간의 이해와 신뢰구축 26.3%, 연봉제의 구성원들에 대한 긍정적인 태도 16.8%, 연봉제에 대한 최고경영자(주체)의 확고한 신념 12.3%, 연봉산정의 기준이 되는 목표치의 달성가능 10.5% 순으로 나타났다. 또한 치과의원 종사자가 치과병원 종사자보다 연봉제가 성과를 거두기 위해서는 연봉제의 구성원에 대한 긍정적인 태도(p<.05)가 전제되어야 한다고 인식하였고, 치과의사가 치과위생보다 연봉산정의 기준이 되는 목표치의 달성가능(p<.001)이 전제되어야 한다고 인식하였다.

• 대한물리치료과학회지
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• 제7권1호
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• pp.377-396
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• 2000

After warming-up exercise for 20 minutes, Isokinetic measurement of trunk strength for flexor and extensor was done by using Cybex 6000 TEF Unit on 91 healthy male white workers from 22years old to 49 years old, and compared each other. 20 repetitions of trunk extension-flexion were done at $120^{\circ}$/sec angular velocity. After resting for 1 minutes, Four repetitions at two different angular velocities($60^{\circ}$/sec, $120^{\circ}$/sec) were done with 30 seconds of resting interval between each angular velocity. The purpose of this study is to obtain the isokinetic normative strength values for trunk extensors and flexors, and is to know the correlation between age, height, weight of subjects and data from isokinetic trunk strength measurement, and is to provide a guideline for exercise program of male white collar workers The collected data were analyzed by ANOVA, Duncan's Multiple Range Test, and Pearson correlation coefficiency in PC-SAS program. The results obtained were as follow; 1. There is significant positive-correlation with the statistic value between weight and peak torque of trunk muscles at two different angular velocities($60^{\circ}$/sec, $120^{\circ}$/sec)(p<01), between height and peak torque of trunk muscles at two different angular velocities($60^{\circ}$/sec, $120^{\circ}$/sec) except peak torque of trunk flexor at $60^{\circ}$/sec(p<01). 2. There is nagitive-correlation between age and peak torque of trunk muscles at two different angular velocities($60^{\circ}$/sec, $120^{\circ}$/sec), there is significant differences with statistic value between age and peak torque of trunk extensor at $120^{\circ}$/sec(p<.01). 3. Mean peak torque and mean peak torque % by body weight of trunk extensor is 1.1 times higher values than trunk flexor at $60^{\circ}$/sec. 4. There is the increase in peak torque angle of trunk flexor with increasing of age, and the decrease in peak torque angle of trunk flexor with increasing of age at two different angular velocities($60^{\circ}$/sec, $120^{\circ}$/sec). there is significant differences with statistic value in peak torque angle of trunk flexor at $120^{\circ}$/sec(p<.01). 5. There is significant decrease in endurance ratio of trunk extensor with increasing of age at $120^{\circ}$/sec(p<.01). In conclusion, peak torque of trunk extensor is 1.1 times higher values than trunk flexor in healthy male white collar workers.

• 대한한의학회지
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• 제42권3호
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• pp.26-43
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• 2021

Objectives: This study is designed to statistically analyze data of outpatients visiting for recent 3 years. The purpose is to identify tendencies of patients who visit the hospitals before and after COVID-19. Methods: This study retrospectively analyzed the medical records of 452,487 patients who visited to the Daejeon·Cheonan·Cheongju Korean Medicine Hospital of Daejeon University from January 1, 2018 to August 31, 2020. The data is classified according to year, month, gender, age, and visit type. The statistical analysis was performed using IBM SPSS 25.0. Results: The total number of patients decreased in 2020 compared to before 2020, and the number of patients in each hospital also decreased from the previous year. According to the year of each hospital, the difference by year was not statistically significant at Daejeon Hospital, but Cheonan and Cheongju Hospital showed statistical difference. The change in monthly according to the year by hospital has continued to decrease from January to March in 2020, unlike the previous year, which recovered from a decline in March. In the analysis of patients by age, there was no statistically significant difference in the number of patients in the above 60s according to the year, while those under 60s have a tendency to significantly decrease. Conclusion: We expect that the results of this study will be used as reference materials in analyzing effects of COVID-19 at health care utilization.

• 유통과학연구
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• 제11권12호
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• pp.5-11
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• 2013

Purpose - The purpose of this study was to construct a turnover estimation model by investigating research by Park et al. (2006) on the market area of domestic distribution. The study investigated distribution by using a new tool for the turnover estimation technique. This study developed and discussed the turnover estimation technique of Park et al. (2006), applying it to a large-scale retailer in "D"city that was suitable for on-the-spot distribution. It constructed the new model in accordance with test procedures keeping to this retail business location, to apply its procedures to a specific situation and improve the turn over estimation process. Further, it investigated the analysis and procedures of existing turnover estimation cases to provide problems and alternatives for turnover estimation for a large-scale retailer in "D"city. Finally, it also discussed problems and scope for further research. Research design, data, and methodology - This study was conducted on the basis of "virtue" studies. In other words, it took into account the special quality of the structure of Korea's trade zones. The researcher sought to verify a sale estimate model for use in a distribution industry's location. The main purpose was to enable the sale estimate model (that is, the individual model's presentation) to be practically used in real situations in Korea by supplementing processes and variables. Results - The sale estimate model is constructed, first, by conducting a data survey of the general trading area. Second, staying within the city's census of company operating areas, the city's total consumption expenditure is derived by applying the large-scale store index. Third, the probability of shopping is investigated. Fourth, the scale of sales is estimated using the process of singularity. The correct details need to be verified for the model construction and the new model will need to be a distinct sale estimate model, with this being a special quality for business conditions. This will need to be a subsequent research task. Conclusions - The study investigated, tested, and supplemented the turnover estimation model of Park et al. (2006) in a market area in South Korea. Supplementation of some procedures and variables could provide a turnover estimation model in South Korea that would be an independent model. The turnover estimation model is applied, first, by undertaking an investigation of the market area. Second, a census of the intercity market area is carried out to estimate the total consumption of the specific city. Consumption is estimated by applying indexes of large-scale retailers. Third, an investigation is undertaken on the probability of shopping. Fourth, the scale of turnover is estimated. Further studies should investigate each department as well as direct and indirect variables. The turnover estimation model should be tested to construct new models depending on the type of region and business. In-depth and careful discussion by researchers is also needed. An upgraded turnover estimation model could be developed for Korea's on-the-spot distribution.

• 한국식품영양과학회지
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• 제43권9호
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• pp.1431-1438
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• 2014

본 연구는 국내 노인의 삶의 질과 영양개선 및 건강을 증진시킬 수 있는 기초자료를 얻고자 실시된 단면연구로서 재가 노인의 식욕부진 유병 상태를 조사하고, 식욕부진과 관련된 사회 인구학적 특성, 병리적 특성과 심리 특성 및 일상생활 수행능력 등을 조사하였다. 자료 수집은 서울, 경기, 충북 지역의 65세 이상 재가 노인 419명을 대상으로 2012년 9월에서 12월까지 구조화된 설문지를 이용하여 일대일 면접방법으로 수행하였다. 연구 결과 국내 노인의 식욕부진 유병률은 전체 응답자 가운데 35.1%였고, 특히 남성노인의 식욕부진 유병률이 여성노인보다 유의하게 높았다. 남성노인의 식욕부진은 중추신경계 질환을 진단받은 경우가 가장 많았고 여성노인의 경우 식욕부진은 내분비 질환이 있는 경우가 가장 많았다. 또한 우울증 증상이 있거나 일상생활에서 의존도가 높은 경우 식욕부진이 현저한 것으로 관찰되었다. 이상의 결과로부터 국내 재가 노인들의 식욕부진이 심각한 수준임을 알 수 있었고, 노인의 식욕부진은 생리적 특성과 병리적 특성은 물론 우울과 같은 심리적 특성과도 깊은 상관성이 있음을 알 수 있었다. 향후 노인의 식욕부진 개선이나 예방을 위하여 구체적인 영양중재와 영양치료가 필요하며, 노인인구 증가에 따라 노인의 식욕증진을 고려한 노인식품 개발이 시급히 필요할 것으로 생각된다. 본 연구 결과는 다음과 같은 제한점을 갖는다. 본 조사는 단면연구이므로 연구 결과에서 나타난 식욕 수준에 관련된 인자들이 노인의 식욕부진 원인으로 작용했는지는 알 수 없다. 따라서 추후 보다 대표성을 갖는 한국 노인을 대상으로 노인의 식욕부진 유병률의 조사는 물론 식욕부진과 관련된 원인 규명을 위하여 횡단연구가 필요하다. 또한 노인을 일대일 대면하여 자가보고 하는 방법으로 자료를 수집하였으므로 문항에 따라서는 노인에 따라 사실보다 과장하거나 축소하는 등 응답 수준이 주관적일 수도 있다. 그럼에도 불구하고 본 연구에서 나타난 식욕부진과 관련된 인자들은 선행 연구와 유사하며 따라서 자가보고에 의한 사회적 기대 효과는 다소 적었다고 판단된다. 향후 재가노인의 범위를 성별, 연령별, 지역별, 거주형태별 등으로 일치시키고 확대하여 노인의 식욕부진 실태와 관련 인자 연구의 확대를 제안한다.

• 한국치위생학회지
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• 제9권4호
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• pp.768-783
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• 2009

Objectives : The purpose of this study was to analyze dental records performed through a dental hygiene process and provide basic data on clinical training education for dental hygienists. Methods : The dental hygiene records of 440 senior dental hygiene students in Y University from March 2005 to September 2008, were examined. The needs of the clients confirmed by the dental hygiene diagnosis was based on Human Need Theory. The client's needs and the number of visits were analyzed according to the general characteristics(gender, age). The contents of the dental hygiene implementation performed according to the needs were divided into dental hygiene care and oral health education. The dental hygiene evaluation was classified into 'Met of Goal', 'Partially Met of Goal', and 'Unmet of Goal' according to the dental hygiene diagnosis. Data analysis was performed for the Frequency statistics and a Fisher's exact test using SPSS 12.0K for Windows. Results : 1. The clients were mostly aged in their 20's(307 clients). 2. The dental hygiene care usually performed was 'Scaling' and 'Recommendation to visit a dental clinic', and the education performed was 'How to brush teeth'. The implementation result from the need to Freedom of Stress was as simple as 'Be careful when treating' and 'Explanation of medical treatment and tools'. 3. The dental hygiene evaluation showed a higher met rate in the field of education than in that of the dental hygiene care. The reason for unmet the goal was 'Lack of the client's efforts and they didn't visit dental clinic'. Conclusions : The search for a range of clients for dental hygiene process should be made through effective connections between the local community institutions and schools. It was suggested that they should be strength the practical exercises for clients suffering dental anxiety and stress in dental treatments. In addition, education and attempts to motivate the clients should be performed according to their characteristics.

• 디지털융복합연구
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• 제15권2호
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• pp.493-501
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• 2017

본 연구는 서울 및 경기도에 거주하는 40~50대 중년기 여성 230명을 대상으로 건강상태, 생활습관, 심리적 상태에 따른 노화인식을 조사하여 중년기에 급격하게 진행되는 노화를 예방하고 신체적, 정신적으로 건강한 노후를 맞이할 수 있는 미용적 대안을 제시하고자 하였다. 자료수집은 2015년 7월 25일부터 2015년 9월1일까지 진행하였으며, 빈도분석, 독립표본 t-test, ANOVA 및 Duncan test로 분석하였다. 연령이 높을수록 폐경비율이 높았고, 음주, 운동량, 수면시간이 줄어든 반면 스트레스와 심리적 압박감은 더 큰 것으로 나타났다. 폐경여부에 따라 안면노화의 상태는 유의미한 차이를 보였고(${\chi}^2=39.692^{***}$, p<.001), 여가(취미)활동의 여부에 따라서도 차이를 나타냈다(${\chi}^2=22.470^{***}$, p<.01). 또, 노화의 진행정도, 노화에 대한 불안감, 개선을 위한 노력 등의 항목에서 연령이 높을수록, 폐경에 가까울수록 부정적인 인식을 보여 50세 전후의 노화와 폐경은 매우 자연스러운 현상이지만 제2의 사춘기와도 같은 이 시기를 겪는 40~50대 중년기 여성들을 위한 미용적 대안이 마련된다면 성공적 노후를 맞이하는데 도움이 될 것으로 생각된다.

• 보건의료생명과학 논문지
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• 제10권2호
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• pp.351-359
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• 2022

본 연구 대상자는 충청북도 E군에 소재한 G대학교 임상실습을 경험한 간호학과 3,4학년 재학생 167명을 대상으로 실시하였다. 자료수집기간은 2020년 12월 1일부터 12월 18일까지 이루어졌다. 수집된 자료는 SPSS 26.0 프로그램을 이용하여 분석하였으며, 대상자의 일반적 특성, 임상실습 스트레스와 임상실습만족도는 빈도와 백분율, 평균, 표준편차로 분석하였고, 일반적 특성에 따른 임상실습 스트레스, 임상실습만족도, 간호전문직관의 차이는 t-test와 one way ANOVA로 분석하였다. 임상실습 스트레스, 임상실습만족도, 간호전문직관의 상관관계는 Pearson Correlation Coefficients로 분석하였고, 간호전문직에 미치는 요인을 분석하기 위해 stepwise multiple regression을 이용하여 분석하였다. 연구결과 전공만족도(β=.256, p=.001)가 가장 강력한 영향변수였으며, 임상실습만족도(β=.237, p=.004), 임상실습 스트레스(β=.-.143, p=.068)순으로 간호전문직관에 영향을 주는 요인으로 확인되었다. 이들 전체변수의 설명력은 21.8%로 나타났다(F=.14..44, p=.000). 이상의 연구결과로 간호전문직관을 향상시키기 위한 교육전략 및 구체적인 프로그램을 개발 및 적용이 필요함을 시사한다.