• Title/Summary/Keyword: head proportion

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End Stage Palliative Care of Head and Neck Cancer: a Case Study

  • Shishodia, Nitin Pratap;Divakar, Darshan Devang;Al Kheraif, Abdulaziz Abdullah;Ramakrishnaiah, Ravikumar;Pathan, Akbar Ali Khan;Parine, Narasimha Reddy;Chandroth, Santhosh Vediyera;Purushothaman, Binu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1255-1258
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    • 2015
  • Background: Locally advanced head and neck cancer is generally incurable and has a short survival rate. This study aimed to evaluate symptom relief, disease response, and acute toxicity after palliative hypo-fractionated radiotherapy and long-term survival in affected patients. Materials and Methods: Between January 2011 to December 2011, 80 patients who were histopathologically diagnosed as having stage III or stage IV head and neck squamous cell carcinoma based on Eastern Cooperative Oncology Group (ECOG) performance status 1-3, were offered palliative radiotherapy (20 Gy/5Fr/5 Days). Later these patients were evaluated on 30th day after completion of treatment for disease response based on World Health Organisation (WHO) criteria and palliation of symptoms using symptomatic response grading and acute toxicities by the Radiation Therapy Oncology Group (RTOG). Many patients were given post radiation therapy (RT) palliative chemotherapy for appropriate palliative care and a few patients were selected for further curative RT. The overall survival was also evaluated among this group of patients with last follow up date of 1st May, 2014. Results: The most common presenting complaint was pain followed by dysphagia. Most patients (60-70%) had appreciable relief in their presenting symptoms. A good response was observed in the majority following palliative RT; a few patients had progressive disease and some had stable and regressed disease. None of the patients experienced radiation toxicity that required hospital admission. Almost all showed grade one and two acute skin and mucosal toxicity one month after completion of treatment. The mean survival days for patients given only hypofractionated palliative RT was 307 days, those with post palliative RT and palliative chemotherapy was 390 days and patients who went on to receive further palliative RT and curative RT dose had significantly overall survival of 582 days. Conclusions: Advanced head and neck cancer should be identified for suitable palliative hypofractionated radiotherapy to achieve acceptable symptom relief in a great proportion of patients and should be followed by palliative chemotherapy or curative RT in suitable cases for long-term symptom-free survival.

Compressibility and Permeability Characteristics of Bentonite-Soil/Sand Mixes (벤토나이트-흙/모래 혼합토의 압축 및 투수 특성 연구)

  • 송창섭;윤병옥;반창현
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.40 no.2
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    • pp.123-129
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    • 1998
  • Compressibility and permeability properties are the most important input parameters necessary to assess the suitability of core materials in seepage control system construction. To achieve this objective, an experimental investigation was conducted in the laboratory. For the bentonite-soil/sand mixes, consolidation and permeability tests were carried out in the conventional consolidation cell, 6Omm in diameter and 2Omm in height, was modified to perform a falling head type permeability test. From the results, the normalized relationship with respect to void ratio at liquid-limit state $(e_L)$, and the changes of compressibility and permeability for various bentonite-soil/sand mixes were presented. This approach will be helpful in proportioning mixes and predicting corresponding changes in engineering behavior. And it is possible to proportion a mix to arrive at the required compressibility without affecting the permeability.

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Effects of Yukmijihwangwon in Rat Models of intracerebral hemorrhage (뇌출혈 동물모델에서 육미지황원의 효과 연구)

  • Kang, Bong-Joo;Cho, Dong-Wuk
    • Korean Journal of Oriental Medicine
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    • v.7 no.1
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    • pp.125-134
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    • 2001
  • Intracerebral hemorrhage (ICH) is associated with a considerable proportion of strokes and head injuries. The mechanism of brain cell injury associated with hemorrhage may be different from that due to pure ischemia. Therefore, it is essential that models of intracerebral hemorrhage be developed and well characterized in animal model. Yukmijihwangwon (YM) has been known to reinforce the vital essence and have antioxidant activities. In this study, the protective effects of YM was investigated against ICH in animal models. Adult rats had 2 microliters saline containing 0.5 and 5 unit bacterial collagenase infused into the right caudate nucleus. It was found out that YM was effective in protecting brain against ICH.

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The sexual dimorphism of Mauremys reevesii (남생이의 성적 이형성)

  • OH Jungwoo;NAM Sangheon;LEE Sungkyung;KANG Junghoon
    • Korean Journal of Heritage: History & Science
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    • v.56 no.1
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    • pp.132-140
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    • 2023
  • In this study, a total of 21 parts of the head, carapace, and plastron of 21 tortoises were examined to investigate the characteristics of male and female sexual dimorphism of the Reeve's turtle (Mauremys reevesii), a natural monument in Korea. The ratio values of a total of 19 areas were derived from Head Length (HL) and Carapace Length (CL). As a result of comparing the ratio values, it was found that male tortoises had larger head length, head width, and head height than females compared to the size of the carapace. Since females grow eggs inside the body through internal fertilization after mating, female carapaces are judged to be larger than males overall. As a result of statistical analysis of the ratio values of the measured values, Plastron Length (PL), Bridge Length (BL), Gular Length (GL), Interhumeral Length (IH), Interanal Length (IAN), Femoral-Anal seam (FA) and Head Height (HH) showed statistically significant differences. Statistically significant in the part of the plastron, it is judged that the tortoise acts directly on each deck of the plastron as it grows. In addition, the head size of male tortoises was smaller than that of females, but it was found to be larger in proportion. It is considered that the tortoise has a rather large head compared to the body due to the male's habit of shaking his head and courtship behavior before mating. This study, we were able to identify the characteristics of sexual dimorphism in Reeve's turtle. However, since most of them were rescued, it was not possible to accurately determine habitat and age. In the future, if additional studies are conducted on individuals with clear habitats and ages, it is expected that the characteristics of the physical differences that develop as they grow can be identified.

Classification and Characterization of Bacteriophages of Lectobacillus casei (Lactobacillus casei Bacperiophage의 분류 및 특성에 관한 연구)

  • 김영창;박민철;강국희;윤영호;이광웅
    • Korean Journal of Microbiology
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    • v.17 no.4
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    • pp.165-178
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    • 1979
  • Phages of Lactobaciilus casei (PLC) isolated from plant drainage were classified and characterized. The results are as follows : 1. On the basis of host range pattern, phages could be divided into 2 groups (PLC-B and PLC-C). PLC-B group phages could be further divided into 5 sub-groups $(B_1, \;B_2, \;B_3, \;B_4, \;and\;B_5)$. Although PLC-C group phages had the same host range, they could be also divided into 2 sub-groups $(C_1\;and\;C_2)$ by morphlogical type. 2. It was $B_3$ group phages that represented a major proportion (44.4%) of phages tested. However, $B_1$ group phages were shown to have the widest host range. 3. Electron micrographs revealed that the phages fell into three different morphological types. $(B_1, \;B_2, \;and\;B_3)$ group phages hd a hexagonal head (52nm in diameter) and a sheathless noncontractile (245 nm in length). $B_4\;and\;C_2$ group phages had a hexagonal head (56 nm) and a short flexible tail (169nm) having no sheath. $B_5\;and\;C_1$ group phages were shown to have a hexagonal head (81 nm) and a contractile tail (140 nm) having a sheath, a base plate and tail fibers. 4. The inactivation of the phages by antisera indicated that serological relationships correlated completely with morphological types. 5. $B_1, \;C_1\;and\;C_2$ group phages produced a large (1, 2 mm in diameter) plaque with a clear ring. The morphology of plaques of $B_3\;and\;B_5$ group phages was the same as those produced by the above, but the average plaque sizes for $B_3\;and\;B_5$ were 0.8 mm abd 0.5 mm, respectively. $B_2\;and\;B_4$ group phages produced a small (0.5 mm) turbid plaque with an irregular edge. 6. The latent period and the average burst size of $B_1\;and\;B_3$ group phages were 90 min and 100, respectively. These phages reuqired calcium ions for their miltiplication. 7. $B_3$ group phages could not be absrobed to R-variant $KC_1$. 8. The order of resistance of phages to heat was $B_2\;>\;B_1, B_4\;and\;B_5\;>\;B_3\;and\;C_2, \;B_5$ group phages were more stable than $B_3$ in various pH values. $C_2$ group phages were more sensitive to UV irradiation than $B_1\;and\;B_3$ group phages. 9. Strains YIT9018 and IAM 1043 were induced by mitomycin C treatment. Phage particles detected in the lysates had a hexagonal head (38 and 49 nm, respectively), but no tail. Any sensitive indicator strain could not be isolated in spite of repaeated trials.

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Estimation of the Reliability of Water Distribution Systems using HSPDA Model and ADF Index (HSPDA 모형 및 ADF index를 이용한 상수관망의 신뢰도 산정)

  • Baek, Chun-Woo;Jun, Hwan-Don;Kim, Joong-Hoon
    • Journal of Korea Water Resources Association
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    • v.43 no.2
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    • pp.201-210
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    • 2010
  • In this study, new methodology to estimate the reliability of a water distribution system using HSPDA model is suggested. In general, the reliability of a water distribution system can be determined by estimating either the ratio of the required demand to the available demand or the ratio of the number of nodes with sufficient pressure head to the number of nodes with insufficient pressure head when the abnormal operating condition occurs. To perform this approach, hydraulic analysis under the abnormal operating condition is essential. However, if the Demand-Driven Analysis (DDA) which is dependant on the assumption that the required demand at a demand node is always satisfied regardless of actual nodal pressure head is used to estimate the reliability of a water distribution system, the reliability may be underestimated due to the defect of the DDA. Therefore, it is necessary to apply the Pressure-Driven Analysis (PDA) having a different assumption to the DDA's which is that available nodal demand is proportion to nodal pressure head. However, because previous study used a semi-PDA model and the PDA model which had limited applicability depending on the characteristics of a network, proper estimation of the reliability of a water distribution system was impossible. Thus, in this study, a new methodology is suggested by using HSPDA model which can overcome weak points of existing PDA model and Available Demand Fraction (ADF) index to estimate the reliability. The HSPDA can simulate the hydraulic condition of a water distribution system under abnormal operating condition and based on the hydraulic condition simulated, ADF index at each node is calculated to quantify the reliability of a water distribution system. The suggested model is applied to sample networks and the results are compared with those of existing method to demonstrate its applicability.

The characteristics of mild head injuries in preschool-age children fall: a retrospective observational study (학령전기 소아에서 추락으로 인한 경증 두부손상의 특징에 대한 후향적 관찰 연구)

  • Sung, Min Suk;Lee, Ji Sook;Jeon, Woochan;Park, Junseok;Kim, Kyung Hwan;Shin, Dongwun;Kim, Hoon;Park, Joon Min;Kim, Hyunjong
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.423-429
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    • 2018
  • Objective: Falling is a common cause of head injury in preschool aged children. We investigated the characteristics of mild head injuries caused by falling and the association between body weight and occurrence of traumatic brain injuries (TBI). Methods: This retrospective observational study was conducted on head-injured preschool-aged children that visited the emergency department from January 2012 to December 2015. Characteristics such as age, sex, weight, free fall height, floor type, and presence of TBI, as defined as cerebral hemorrhage or skull fracture, were investigated. We calculated body weight percentiles by calibrating age and weight and categorized them into four quartile ranges. We grouped all included cases into two groups according to the presence of TBI. The characteristics of the two groups were compared by using chi-square test, and the association with TBI was investigated by using binomial logistic regression. Results: A total of 701 children were included, and TBI was observed in 95 children. Children with TBI were younger. The proportion of children with TBI was higher in the third and fourth quartiles of the body weight group as well as according to soft floor and fall from high height (${\geq}1m$). The odds of soft floor being associated with TBI was higher than the odds for hard floor (odds ratio, 2.734; 95% confidence interval [CI], 1.597-4.680). The odds of high height (${\geq}1m$) being associated with TBI was higher than that for low height (odds ratio, 2.306; 95% CI, 1.155-4.601), and the odds ratio for the weight percentile group was 1.228 (95% CI, 1.005-1.499). Conclusion: Prevalence of TBI after falling in preschool-aged children might be associated with high fall-height and body weight quartiles.

The comparative analysis on the distribution of cancers (암환자 분포의 비교 분석)

  • Kim, Seung-Kook
    • The Journal of Korean Society for Radiation Therapy
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    • v.12 no.1
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    • pp.155-165
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    • 2000
  • This paper is based on the records of researching the patients with cancer in the Chunnam National University Hospital from January 1990 to December 1999 and referred to the Korea Cancer Center Hospital's annual report. The results are as the following : 1. Along the total O.P.D 5,680,284, the patients of therapeutic radiology are 201,367 in $3.55\%$ 2. Among the 12,404 cancer patients, stomach cancer patients are $2,048(16.51\%),\;liver\;cancer\;patients\;are\;1,490(12.01\%),\;lung\;cancer\;patients\;are\;1,418(11.43\%)\;cervix\;and\;uterus\;cancer\;patients\;are\;1,102(8.88\%)$ and sexual ratio of male to female appeared 1.38 : 1 Therefore, male cancer patients are more than female patients. 3. The age distribution of cancer was $2,791(22.50\%)\;by\;55{\sim}64\;age,\;2,582(20.82\%)\;by\;45{\sim}54\;age,\;and\;2,530(20.40\%)\;by\;65{\sim}74\;age.\;Therefore,\;the\;60\%\;of\;all\;cancer\;patients\;were\;45{\sim}75$ ages. 4. Among the 9,815 therapeutic radiology patients, $1,755(17.89\%)\;are\;in\;the\;uterus\;system,\;1,534(15.63\%)\;are\;in\;the\;head\;and\;neck,\;1,519(15.48\%)$ are in the lung. Therefore, the proportion of three kinds of therapeutic radiology patients is about $50\%$. 5. The occupational distributions of 12,404 cancer patients$(90{\sim}99\;year)\;are\;2,795(22.53\%)\;by\;orderly\;farmers,\;2,763(22.28\%)\;by\;house\;wives,\;586(4.71\%)\;by\;businessmen,\;and\;391(3.15\%)$ by public service personnel. Industrial, miners, forest men, soldiers didn't nearly appear. 6. The number of patients of cancer diagnosis was $9,431(76.03\%)\;by\;the\;biopsy\;of\;primary\;region,\;and\;2,201(17.74\%)$ by clinical examination Therefore, those two kinds of methods took a propertion of about $94\%.\;The\;number\;of\;deceases\;on\;departments\;was\;153(32.42\%)\;in\;PD,\;133(28.18\%)\;in\;GI,\;63(13.35\%)$ in GS. Therefore, those three kinds of deceases took a proportion of about $74\%$.

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Development of Fishway Assessment Model based on the Fishway Structure, Hydrology and Biological Characteristics in Lotic Ecosystem

  • Choi, Ji-Woong;Park, Chan-Seo;An, Kwang-Guk
    • Journal of Ecology and Environment
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    • v.39 no.1
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    • pp.71-80
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    • 2016
  • The main goal of this study is to develop a multi-metric fishway assessment model (Mm-FA) and evaluate the efficiency of fishway. The Mm-FA model has three major fishway components with nine metrics: structural characteristics, hydraulic/hydrologic features, and biological attributes. The model was developed for diagnosing and assessing fishway efficiency and tested to Juksan Weir at the Yeongsan River Watershed. Structural characteristics of fishway included slope of the fishway (M1), ratios of fishway width to stream width (M2), and the proportion of orifice clogging and orifice size (M3). Hydraulic/hydrologic characteristics included depth of fishway entrance head (M4), depth of exit tail (M5), and current velocity of inner fishway (M6). Biological characteristics included fish species ratio of inner fishway to upper-lower weir (M7), fish length distribution (M8), and the proportion of migratory fish species to the total number of species (M9). Overall, the assessment of fishway efficiency showed the total score of the Mm-FA model was 25 in the Juksan Weir, indicating "good condition" by the criteria of the five-level classification system. The Mm-FA model may be used as a key tool for the assessment of fishway efficiency, especially on the 16 weirs constructed for the "Four Rivers Restoration Project" after a partial calibration of Mm-FA model.

Feed intake, digestibility and energy partitioning in beef cattle fed diets with cassava pulp instead of rice straw

  • Kongphitee, Kanokwan;Sommart, Kritapon;Phonbumrung, Thamrongsak;Gunha, Thidarat;Suzuki, Tomoyuki
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.9
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    • pp.1431-1441
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    • 2018
  • Objective: This study was conducted to assess the effects of replacing rice straw with different proportions of cassava pulp on growth performance, feed intake, digestibility, rumen microbial population, energy partitioning and efficiency of metabolizable energy utilization in beef cattle. Methods: Eighteen yearling Thai native beef cattle (Bos indicus) with an average initial body weight (BW) of $98.3{\pm}12.8kg$ were allocated to one of three dietary treatments and fed ad libitum for 149 days in a randomized complete block design. Three dietary treatments using different proportions of cassava pulp (100, 300, and 500 g/kg dry matter basis) instead of rice straw as a base in a fermented total mixed ration were applied. Animals were placed in a metabolic pen equipped with a ventilated head box respiration system to determine total digestibility and energy balance. Results: The average daily weight gain, digestible intake and apparent digestibility of dry matter, organic matter and non-fiber carbohydrate, total protozoa, energy intake, energy retention and energy efficiency increased linearly (p<0.05) with an increasing proportion of cassava pulp in the diet, whereas the three main types of fibrolytic bacteria and energy excretion in the urine (p<0.05) decreased. The metabolizable energy requirement for the maintenance of yearling Thai native cattle, determined by a linear regression analysis, was $399kJ/kg\;BW^{0.75}$, with an efficiency of metabolizable energy utilization for growth of 0.86. Conclusion: Our results demonstrated that increasing the proportion of cassava pulp up to 500 g/kg of dry matter as a base in a fermented total mixed ration is an effective strategy for improving productivity in zebu cattle.