• 제목/요약/키워드: hazards analysis

검색결과 974건 처리시간 0.029초

고사리와 도라지 제조공정 중 살균공정에 대한 미생물학적 위해 요소에 관한 연구 (A Study on Microbiological Hazards in Sterilization Processing of Pteridium aquilinum and Platycodon grandiflorum)

  • 최선효;권상철
    • 한국산학기술학회논문지
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    • 제17권1호
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    • pp.646-653
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    • 2016
  • 본 연구는 고사리와 도라지의 HACCP(Hazard Analysis Critical Control Point)시스템 적용에 필요한 미생물학적 위해 요소 분석을 위한 목적으로 수행되었다. 제조공정도는 일반적인 제조업체의 제조공정을 참고하여 작성하였다. 원료농산물의 미생물학적 위해요소 분석결과 일반세균수는 도라지에서 $6.2{\times}10^3CFU/g$ 로 가장 많이 검출되었다. 하지만, 소독공정 이후의 미생물검사 결과는 모든 균이 검출되지 않아 안전한 것으로 나타났다. 제조환경과 작업자의 미생물 검사 결과, 체계적인 세척 및 소독을 통하여 작업자 위생교육 등을 기반으로 개인위생과 함께 미생물학적 위해를 감소시켜야 할 것으로 사료된다.

Hepatocellular Carcinoma: Texture Analysis of Preoperative Computed Tomography Images Can Provide Markers of Tumor Grade and Disease-Free Survival

  • Jiseon Oh;Jeong Min Lee;Junghoan Park;Ijin Joo;Jeong Hee Yoon;Dong Ho Lee;Balaji Ganeshan;Joon Koo Han
    • Korean Journal of Radiology
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    • 제20권4호
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    • pp.569-579
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    • 2019
  • Objective: To investigate the usefulness of computed tomography (CT) texture analysis (CTTA) in estimating histologic tumor grade and in predicting disease-free survival (DFS) after surgical resection in patients with hepatocellular carcinoma (HCC). Materials and Methods: Eighty-one patients with a single HCC who had undergone quadriphasic liver CT followed by surgical resection were enrolled. Texture analysis of tumors on preoperative CT images was performed using commercially available software. The mean, mean of positive pixels (MPP), entropy, kurtosis, skewness, and standard deviation (SD) of the pixel distribution histogram were derived with and without filtration. The texture features were then compared between groups classified according to histologic grade. Kaplan-Meier and Cox proportional hazards analyses were performed to determine the relationship between texture features and DFS. Results: SD and MPP quantified from fine to coarse textures on arterial-phase CT images showed significant positive associations with the histologic grade of HCC (p < 0.05). Kaplan-Meier analysis identified most CT texture features across the different filters from fine to coarse texture scales as significant univariate markers of DFS. Cox proportional hazards analysis identified skewness on arterial-phase images (fine texture scale, spatial scaling factor [SSF] 2.0, p < 0.001; medium texture scale, SSF 3.0, p < 0.001), tumor size (p = 0.001), microscopic vascular invasion (p = 0.034), rim arterial enhancement (p = 0.024), and peritumoral parenchymal enhancement (p = 0.010) as independent predictors of DFS. Conclusion: CTTA was demonstrated to provide texture features significantly correlated with higher tumor grade as well as predictive markers of DFS after surgical resection of HCCs in addition to other valuable imaging and clinico-pathologic parameters.

1998 - 2008 발생한 식품안전관련 사건.사고 분석 (The Analysis of Food Safety Incidents from 1998 to 2008 in Korea)

  • 박경진
    • 한국식품위생안전성학회지
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    • 제24권2호
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    • pp.162-168
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    • 2009
  • 식품안전관련 사건 사고는 점차 대형화되면서 지속적으로 계속 발생하고 있다. 이에 본 연구에서는 1998년 1월부터 최근 2008년 10월까지 국내에서 발생한 주요 식품안전사건사고와 관련하여 다양한 언론매체에서 발표된 자료를 수집하고 그 발생현황에 대한 분석을 시도하였다. 총 1,206건이 발생한 것으로 조사되었으며, 이중 중복내용과 순수 식품안전사건 사고와 관련이 없는 부분을 제외하면 약 11년간 총 569건이 발생한 것으로 조사되었다. 이를 연도별로 보면 평균 51.7건이, 월별로 보면 평균 4.9건이 발생하였다. 주요 원인식품군에 있어 수산식품과 식육 및 육가공품, 과자류, 음료류, 특수영양식품군, 다류, 면류, 장류, 우유 및 유제품 등의 순으로 나타났으며, 식품유형에 있어서는 즉석섭취편의식품, 육류, 과자, 건강보조식품, 침출차, 영아용 조제식 및 육가공품, 인삼제품, 체중조절용 조제식품 등의 순으로 나타났다. 위해요소(원인물질)별로는 화학적 위해요소가 247건(43.4%)으로 가장 많이 발생하였으며, 다음이 생물학적 위해요소로 126건(22.1 %), 물리적 위해요소는 97건(17.0%)의 순으로 나타났다. 위해요소의 발생단계에 대한 분석을 보면, 원료차원에서 가장 많은 364건(64%)이 발생하였고, 다음이 제조가공단계로 151건(26.5%), 유통 및 판매단계가 44건(7.7%)으로 나타났다. 본 연구에서와 같은 자료의 정리 및 분석은 추후 식품안전정책 및 HACCP의무적용 등에 있어 우선적으로 다루어야 할 품목을 선정하는 데 있어 중요한 기초자료로 활용될 수 있을 것이다.

화학 생물 위험 대응 시뮬레이션 및 분석 (Simulation and Analysis of Response Plans against Chemical and Biological Hazards)

  • 한상우;서지윤;심우섭
    • 한국시뮬레이션학회논문지
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    • 제30권2호
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    • pp.49-64
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    • 2021
  • 화학·생물(화생) 위험을 초기 단계에 효과적으로 대응하기 위해서는 화생 대응 계획을 체계적으로 발전시켜야 하며, 모델링 및 시뮬레이션은 이를 위한 과학적 수단으로 활용될 수 있다. 그러나 오염 확산 모델링 분야는 많은 발전을 이루고 있으나, 화생 대응 계획을 모의하고 적절성을 분석하는 시뮬레이션 분야는 여전히 초기 단계에 머무르고 있다. 이에 본 논문에서는 화생 오염 탐지, 보호, 제독 등 대응 계획을 과학적으로 모의하기 위한 모델을 제안한다. 먼저 기상 및 지형 조건을 고려하여 예측된 오염 확산 결과를 교전 모델에 반영하는 방법을 제시한다. 이어서 공개된 사상자 예측 기법을 기반으로 전투 모의 개체의 화생 피해를 모의하는 화생 전투 피해 모의 기법을 설계한다. 그리고 화생 위험 탐지·정찰, 제독, 보호 등 화생 위험 대응 계획을 체계적으로 모의하는 과업을 모델링한다. 끝으로 화생 감시소 운용에 의한 오염 탐지의 신속성을 분석하는 한편, 화생 제독소 운용 시 오염 부대 규모와 제독 부대 규모에 따른 제독 소요 시간을 분석함으로써 화생 전투 모의 실험의 가능성을 확인한다. 제안된 모델을 이용하면 향후 군의 화생 방호 체계 및 운용개념에 대한 효과 분석은 물론 재난 방재 및 모의 훈련 분야에서도 일부 활용이 가능할 것으로 기대된다.

대형 언어 모델을 활용한 한국어 식품 리뷰 분석: 감성분석과 다중 라벨링을 통한 식품안전 위해 탐지 연구 (Korean Food Review Analysis Using Large Language Models: Sentiment Analysis and Multi-Labeling for Food Safety Hazard Detection)

  • 최은선;이경희;조완섭
    • 한국빅데이터학회지
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    • 제9권1호
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    • pp.75-88
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    • 2024
  • 최근 온라인 플랫폼에서 구입한 육회를 섭취한 후 식중독 증상을 호소하거나 방울토마토에서 쓴맛이 난다는 리뷰가 뉴스에 등장한 사례가 있다. 이것은 정부 기관, 식품 제조업체나 유통업체가 온라인 플랫폼의 식품 리뷰를 분석하여 식품 위해를 탐지함으로써 소비자 식품안전 위험을 관리할 수 있음을 시사한다. 본 연구는 감성분석과 대형 언어 모델을 활용하여 식품 리뷰를 분석하고, 부정적인 리뷰를 탐지하여 주요 식품안전 위해(식중독, 변질, 화학적 이취, 이물질)를 다중 라벨링하는 분류 모델을 제안한다. 감성 분류 모델에서는 'funnel' 모델이 낮은 False Positive 비율로 부정 리뷰의 오분류 가능성을 최소화하는 데 효과적이었다. 식품안전 위해 다중 라벨링 모델은 GPT-3.5 보다 GPT-4 Turbo를 활용한 것이 재현율과 정확도 모두 96% 이상으로 높은 성능을 보였다. 정부 기관, 식품 제조업체나 유통업체는 제안된 모델을 사용하여 소비자 리뷰를 실시간으로 모니터링하고, 잠재적인 식품안전 문제를 조기에 탐지함으로써 위험을 관리할 수 있다. 이와 같은 시스템은 기업의 브랜드 평판을 보호하고, 소비자 보호를 강화하며, 궁극적으로는 소비자의 건강과 안전을 증진시키는 결과를 가져올 수 있다.

Bayesian Variable Selection in the Proportional Hazard Model

  • Lee, Kyeong-Eun
    • Journal of the Korean Data and Information Science Society
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    • 제15권3호
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    • pp.605-616
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    • 2004
  • In this paper we consider the proportional hazard models for survival analysis in the microarray data. For a given vector of response values and gene expressions (covariates), we address the issue of how to reduce the dimension by selecting the significant genes. In our approach, rather than fixing the number of selected genes, we will assign a prior distribution to this number. To implement our methodology, we use a Markov Chain Monte Carlo (MCMC) method.

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사고 통계 분석을 통한 해양 시추작업 위험요소 제시 및 JSA 기반 위험저감 방안 (Identification of Hazards for Offshore Drilling through Accident Statistics and JSA-based Risk Reduction)

  • 노현정;강관구;박민봉;김형우
    • 한국산업융합학회 논문집
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    • 제23권5호
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    • pp.865-874
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    • 2020
  • Offshore drilling units have a very dangerous working conditions due to the harsh working environment of the ocean and the high possibility of fire or explosion. This study would identify the hazards that emerge from the marine environment in the operation and maintenance phase of offshore drilling units and show how these hazards can be reduced through risk assessment/management. Various risk reduction and management measures were first reviewed, and Job Safety Analysis (JSA) was selected as the risk assessment technique of this study. In order to understand the characteristics of offshore drilling operations, accident statistics of onshore and offshore drilling were analyzed and compared with each other, and major risk factors for offshore drilling were derived. The jobs in which offshore drilling accidents occur more frequently than onshore drilling was analyzed as the job of fastening, transporting and moving pipes and various materials. This result is due to the limited space of the ocean and the work environment that is prone to being shaken by wind, waves and ocean currents. Based on these statistical results, the job of picking and making up drill pipes was selected as a high-risk job, and JSA was performed as an example. A detailed safety check procedure is proposed so that workers can fully recognize the danger and perform work in a safe state that has been confirmed.

Multi-potential capacity for reinforced concrete members under pure torsion

  • Ju, Hyunjin;Han, Sun-Jin;Kim, Kang Su;Strauss, Alfred;Wu, Wei
    • Structural Engineering and Mechanics
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    • 제75권3호
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    • pp.401-414
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    • 2020
  • Unlike the existing truss models for shear and torsion analysis, in this study, the torsional capacities of reinforced concrete (RC) members were estimated by introducing multi-potential capacity criteria that considered the aggregate interlock, concrete crushing, and spalling of concrete cover. The smeared truss model based on the fixed-angle theory was utilized to obtain the torsional behavior of reinforced concrete member, and the multi-potential capacity criteria were then applied to draw the capacity of the member. In addition, to avoid any iterative calculation in the existing torsional behavior model, a simple strength model was suggested that considers key variables, such as the effective thickness of torsional member, principal stress angle, and strain effect that reduces the resistance of concrete due to large longitudinal tensile strain. The proposed multi-potential capacity concept and the simple strength model were verified by comparing with test results collected from the literature. The study found that the multi-potential capacity could estimate in a rational manner not only the torsional strength but also the failure mode of RC members subjected to torsional moment, by reflecting the reinforcing index in both transverse and longitudinal directions, as well as the sectional and material properties of RC members.

A HACCP model for By-products feed production

  • Dooyum, Uyeh Daniel;Woo, Seung Min;Kim, Jun Hee;Lee, Dong Hyun;Ha, Yu Shin
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 2017년도 춘계공동학술대회
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    • pp.136-136
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    • 2017
  • By-products has been considered lately in Total Mixed Ration (TMR) as an alternative to livestock feed around the world. This is due to the high cost of using forage as feed, less expense in exploring by-products of agriculture origin and environmental concerns with their disposal. However, by-products usually contain contaminants and the production process requires fermentation using a storage and fermentation tank. Animal feed is the start point of the food safety chain in the 'farm-to-fork' model. This necessitated a study to model a protocol that will culminate to safe feed production. Hazard analysis and critical control points (HACCP), a systematic preventive approach to food safety from biological, chemical and physical hazards in production processes that can cause the finished product to be unsafe was explored. Implementation of this model provides a mechanism that ensures product safety is continuously achieved. The entire production process of By-products feed production was evaluated using HACCP wizard software. This includes the plant layout, technical standards, storage and fermentation tank cleansing method, staff assignment, safety control method, and distribution. The potential biological, chemical, and physical hazards that may exist in every step of the production process were identified, and then critical control points (CCPs) were selected. This will ensure the safety of products made from livestock that consumes by-product feed. These includes cheese, milk, beef, etc.

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병원조직 구성원의 직장애착에 영향을 미치는 요인 (Factors Affecting on Organizational Commitment of Hospital Employees)

  • 이상곤;감신;박재용;한창현;김건엽;이원기;차병준
    • 보건행정학회지
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    • 제9권1호
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    • pp.201-233
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    • 1999
  • This study was carried out to find out the factors affecting on organizational commitment of hospital employees. For the purpose, the questionnaire-based research was done with 1280 hospital employees who were working in 2 university hospitals and 4 general hospitals located in Taegu City and Kyungpook Province from November 20, 1997 to December 22, 1997. The results of the study were summarized as follows. There were significant correlations among environmental variables, psychological variables, structural variables, vertical conflict, horizontal conflict, job satisfaction, and organizational commitment. By path analysis, variables such as pay, work involvement, work definiteness, met expectations, positive affectivity, distributive justice, job security, expectations before entering a hospital had significant positive effect on job satisfaction in order of size, while, vertical conflict, job opportunity, and horizontal conflict had significant positive effect on job satisfaction in order of size, while, vertical conflict, job opportunity, and horizontal conflict had signifecant negative effect in order of size. Variables such as job satisfaction, job security, work involvement, pay, vertical conflict, met expectations, distributive justice, positive affectivity, work unit control, job autonomy, and job routinization had significant positive direct effect on organizational commitment in order of size, while, job opportunity, job hazards and resource inadequacy had significant negative direct effects in order of size. It was found that the following variables, listed in order of size, had significant total effects on organizational commitment : job satisfaction, job security, job opportunity, work involvement, pay, met expectations, distributive justice, positive affectivity, job hazards, and work unit control. In considering abovc findings, it is recommended that programs for job satisfaction promotion, job security, decrease of intent to leave, work involvement promotion, adequate pay, met expectations, distributive justice, positive affectivity promotion, job hazards decrease, and work unit control grant should be implemented to increase organizational commitment.