• Journal of the Korean GEO-environmental Society
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• v.15 no.9
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• pp.77-85
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• 2014

Recently, the National Emergency Management Agency of Korea has been operating the National Disaster Management System. Nevertheless, there are numerous difficulties in systematic controlling the steep slope DB promptly, because the system's functions in input and control for steep slope information are merely simple. Futhermore, the hazard degrees of steep slope lands nowadays have risen suddenly in accordance with the increase rate of large scale landslides such as the landslide cases of Umyeonmountain, Chuncheon province and others or sever rain storm cases. these lead to rapid increases in frequencies of nature disasters nationally. therefore, it is needed to develop the GIS-based integrated management system for steep slope information in order to manage disasters in advance or high-degree control. This study shows the national GIS-based integrated management system to prevent the disasters that caused by steep slope lands. The integrated management system developed in this study consists of surface information input modules, realtime DB liaison modules of integrated underground information, V-world background map-based GIS, integrated management system for steep slope information user modules, realtime liaison interface modules designed for utilizing steep slope information. Also, tests about stability of data storage, system stability and consistency of processing speed were performed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3613-3618
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• 2014

Stathmin, also called oncoprotein 18, is a founding member of the family of microtubule-destabilizing proteins that play a critical role in the regulation of mitosis. At the same time stathmin has been recognized as one of responsible factors in cancer cells. The aim of this study was to assess stathmin status, its correlations with clinicopathological parameters and its role as a progosnostic marker in EC patients. The protein and mRNA levels of stathmin were examined byimmunohistochemistry (IHC) and in situ hybridization in 100EC tissues and adjacent noncancerous tissues. mRNA and protein expression of stathmin in three EC cell lines(EC9706, ECa109, EC1 commonly used in research) were also analyzed using immunocytochemistry, western blot and in situ hybridization. The prognostic value of Stathmin expression within the tumor tissues were assessed by Cox regression and Kaplan-Meier analysis. We showed that stathmin expression was significantly higher in EC tissues than in adjacent noncancerous tissues. High stathmin immunostaining score in the EC was positively correlated with tumor differentiation, Tumor invasion, Lymph node metastases, and TNM stage. In addition, we demonstrated that three EC cell lines examined, were constitutively expressing a high level of stathmin. Of those, EC-1 showed the strongest mRNA and protein expression for the stathmin analyzed. Kaplan-Meier analysis showed that significantly longer 5-year survival rate was seen in EC patients with high Stathmin expression, compared to those with low expression of Stathmin expression. Furthermore, multivariate Cox proportional hazard analyses revealed that Stathmin was an independent factors affecting the overall survival probability. In conclusion, our data provide a basis for the concept that stathmin might be associated with EC development and progression. High levels of Stathmin expression in the tumor tissues may be a good prognostic marker for patients with EC.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.851-856
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• 2012

Objective: NBS1 plays a key role in the repair of DNA double-strand break (DSB). We conducted this study to investigate the effect of two critical polymorphisms (rs1805794 and rs13312840) in NBS1 on treatment response and prognosis of advanced non-small cell lung cancer (NSCLC) patients with platinum-based chemotherapy. Methods: Using TaqMan methods, we genotyped the two polymorphisms in 147 NSCLC patients. Odds ratios (ORs) and their 95% confidential intervals (CIs) were calculated as a measure of difference in the response rate of platinum-based chemotherapy using logistic regression analysis. The Kaplan-Meier and log-rank tests were used to assess the differences in progression-free survival (PFS) and overall survival (OS). Cox proportional hazards model was applied to assess the hazard ratios (HRs) for PFS and OS. Results: Neither of the two polymorphisms was significantly associated with treatment response of platinum-based chemotherapy. However, patients carrying the rs1805794 CC variant genotype had a significantly improved PFS compared to those with GG genotype (16.0 vs. 8.0 months, P = 0.040). Multivariable cox regression analysis further showed that rs1805974 was a significantly favorable prognostic factor for PFS [CC/CG vs. GG: Adjusted HR = 0.62, 95% CI: 0.39-0.99; CC vs. CG/GG: Adjusted HR = 0.56, 95% CI: 0.32-0.97). Similarly, rs13312840 with a small sample size also showed a significant association with PFS (CC vs. CT/TT: Adjusted HR = 25.62, 95% CI: 1.53-428.39). Conclusions: Our findings suggest that NBS1 polymorphisms may be genetic biomarkers for NSCLC prognosis especially PFS with platinum-based chemotherapy in the Chinese population.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.664-668
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• 2018

Free-standing structures that are especially high are more likely to receive brain attacks caused by lightning. Since special structures are generally part of national industrial structures, lightning strikes mostly cause socio-economic damage. Lightning protection facilities are installed to prevent such lightning damage, but in 2015, support cables on West Sea bridges were hit by lightning, causing a lot of economic damage. Accordingly, the design of a lightning protection system shall establish protective measures after analyzing the risk of debris falling onto the structure. In this thesis, lightning strikes are analyzed directly in relation to the modeling system that operates the actual information collection system for lightning strikes, depending on the location of the tall, free-standing structures, and practical lightning hazard information is provided by a meteorological station. In addition, we propose monitoring and applying a probability correction rate to the calculation of the lightning risk based on the number of lightning strikes directly reaching the ground in order to obtain an effective lightning risk assessment.

• Journal of Labour Economics
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• v.24 no.1
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• pp.207-230
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• 2001

This paper uses the Korean Labor Panel data to investigate changes in the employment types of male workers following their job changes with the classification of workers into three categories: regular wage workers, non-regular wage workers, and self-employed workers. It also estimates a competing-risks hazard model to analyze the determinants of employment types of workers. The results show that the type of employment of a worker at an immediate previous job has a critical importance in determining his employment type at a new job and that the types of employment at jobs other than the immediate previous job also play some role in determining the type of employment at a new job, although their impact declines as the number of intervening jobs increases. A job loser, who worked as a non-regular worker at his immediate previous job, for example, is considerably less likely to find a regular job, but more likely to get reemployed at another non-regular job than one who worked as a regular worker at his immediate previous job. Similarly, a worker who quit self-employment is much less likely to find a regular job but more likely to restart his own business than one who worked as a regular worker at his immediate previous job. These findings suggest that it is not easy at all for a worker who worked as either a non-regular worker or self-employed worker to become a regular worker, although it might be premature to assert that non-regular jobs or self-employed jobs are dead-end jobs. Another interesting finding of this analysis is that a high unemployment rate lowers a probability of reemployment at either regular jobs or self-employed jobs, but raises a non-regular job reemployment probability, which strongly implies that as labor market conditions become adverse to workers the proportion of non-regular employment can rise rapidly.

• Fire Science and Engineering
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• v.31 no.6
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• pp.23-32
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• 2017

Foam block, popularized as the self-interior goods, is susceptible to fire since the main material is the polyethylene flammable synthetic resin. However, it is widely used in homes, offices, and multi-use facilities. In order to understand the fire characteristics of the foam block, two kinds of foam blocks sold in the market (non-fire retardant and fire retardant) were evaluated according to standard of KS F 5660-1 (Reaction to fire test). In addition, the hazard analysis of the gas generated by the combustion of the specimen was performed using the FTIR gas analyzer. The cone calorimeter test showed that the ignition and flame combustion of both two specimens were burned as soon as the radiant heat blocking device was removed, and it was confirmed that the flame could become a rapid propagation factor during the fire. The analysis of the combustion gas through the FTIR gas analyzer showed that both the carbon dioxide and carbon monoxide classified as the common combustion gases and the acrolein, ammonia, and hydrogen cyanide causing serious damage to the human body were detected substantially. This study showed that a foam block product has high ignitionability and generates toxic gases. Hence, it is urgently required to establish the standards used for properly classifying the combustion characteristics of the material on the basis of the use conditions of a foam block product and to prepare the standards on the purpose of use.

• Korean Journal of Organic Agriculture
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• v.27 no.4
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• pp.437-452
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• 2019

The HACCP evaluation standards for the meat packaging plant are divided into general scale HACCP evaluation standard and small scale HACCP evaluation standard. There are 69 evaluation items in the general scale HACCP evaluation criteria, of which 54 items in the prerequisite management and 15 items in the HACCP management are included. The number of small scale HACCP evaluation items are 20 and about 29% of the general scale HACCP evaluation items. This may not be enough to produce a safety livestock products for the purpose of implementing the HACCP system due to the nature of the meat packaging plant, which does not show much difference in the production process or method of product depending on the scale. To improve the small scale HACCP evaluation standard, the importance of each item was compared with the small scale HACCP evaluation based on the rate of non-compliance and the severity levels in the general scale HACCP evaluation items. As a result of the study, 8 items were derived from the prerequisites management, 2 items were derived from the HACCP management, and some similar evaluation items were grouped together. Finally, 10 items were added to the 20 items of the existing small scale HACCP evaluation items. In this study, study on the safety management of domestic livestock products are continuously carried out, so that it is possible to provide safety livestock products to consumers and contributes to securing competitiveness of domestic livestock industry.

• Journal of Soil and Groundwater Environment
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• v.12 no.1
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• pp.64-72
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• 2007

Humans are exposed by a range of pollutants in soil via exposure routes such as ingestion, inhalation, and dermal contact. Risk assessment is a process of evaluating the adverse health effects of chemicals as a result of exposure to stressors, and it is a very useful tool to establish the cleanup goals in contaminated lands. In the exposure assessment that is one of main process in risk assessment, exposure factor plays a significant role to quantify the intake of soil pollutants. However there is a very limited study about the exposure factor applicable to Korea. In this study, we compared the exposure factors applied by the developed countries including the United States and representative European countries, and suggested the exposure factor that might be suitable in our situation. The exposure factors considered in this study include average lifetime, body weight, (exposed) skin surface area, life time, skin absorption, soil-skin adherence factor, and soil ingestion rate. This information is needed to quantitatively estimate the intake of soil pollutants in contaminated lands.

• Fire Science and Engineering
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• v.25 no.6
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• pp.168-177
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• 2011

The combustion test for real box of AC outdoor unit has been performed in this study in order to estimate the fire hazard in multi-system type of AC outdoor unit which is currently used for commercial use. The result showed that in test, there was explosion inside of AC outdoor unit, and flame erupted and fire spread through upper side grill. And then this fire burnt the combustibles such as wires, electronic control board, heat exchange copper plate and plastics etc inside the unit, refrigerant gas pipe was burst due to fire, and accelerated the explosion and flame eruption to outside while the refrigerant was erupting. It is found in this test that the maximum heat release rate of AC outdoor unit is 5,830 kW, the maximum internal temperature measured with infrared camera and thermocouple is $1,201^{\circ}C$, maximum ambient temperature is $881^{\circ}C$, and flame rose higher than about 5 m. It is concluded that the fire in AC outdoor unit cause fire to combustibles around the unit, and may give big damage by generating the secondary fire. It is expected that the result obtained from the test on the real object may be applied to fire realization of AC outdoor unit and estimation of fire spreading to the combustibles around in the future computer simulation.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.329-331
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• 2018

In this paper, we propose a monitoring system that starts with the supply of raw materials for threading, is processed into a lathe machine, and checks for defects of the product are automatically performed by the robot with Smart Factory technology through assembly and disassembly. Completion check according to the production instruction quantity and production instruction is made by checking the production status according to whether or not the raw material is worn by the displacement sensor, and checking the pitch and the contour of the processed female and male to determine OK and NG. The robotic system acts as a relay for loading and unloading of raw materials, pallet transfer, and overall process, and it acts as an intermediary for organically driving. The location information of the threaded products is collected by using the non-contact wireless tag and the energy saving system Production efficiency and utilization rate were checked. The environmental sensor collects the air-conditioning environment data (temperature, humidity), measures the temperature and humidity accurately, and checks the quality of product processing. It monitors and monitors the driving hazard level environment (overheating, humidity) of the product. Controls for CNC and robot module PLC as a heterogeneous system.