• Journal of Nutrition and Health
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• v.36 no.3
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• pp.255-261
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• 2003

Food irradiation has been steadily increasing in many countries in line with increasing international trade and concerns about naturally occurring harmful contaminants in food. Although irradiation provides an excellent safeguard for the consumer by destroying almost 100% of harmful bacteria, it is necessary to ensure the safety of irradiated foods. This study was performed to investigate the effect of an irradiated diet on lipid peroxidation in the plasma, liver, small intestinal mucosa, and lymphocyte DNA damage in mice. Eight-week old ICR mice were assigned to two groups to receive either non-irradiated or irradiated (10 kGy) diets containing 20.38% fish powder and 6.06% sesame seeds for 4 weeks. The resulting changes in the degrees of lipid peroxidation were evaluated based on the level of plasma and liver thiobarbituric acid reactive substance (TBARS), transmission electron micrograph of jejunal mucosa, and free radical-induced oxidative DNA damage in lymphocytes, as measured by alkaline comet assay (single cell gel electrophoresis). The peroxide values of the gamma irradiated diet were measured every week, and the sample for comet assay was taken at the end of the four week experimental period. There was no significant difference in food efficiency ratio between the two groups. The peroxide values of the diet were immediately increased to 35.5% after gamma irradiation and kept on increasing during storage. After 4 weeks, no differences in tissue or plasma TBARS value were observed between the two groups, but epithelial cells of jejumum showed osmiophillic laminated membranous structures, considered as myelin figures,. The oxidative DNA damage expressed as tail moment (TM) increased 30% in the blood lymphocytes of the mice fed the irradiated diet. In conclusion, the comet assay sensitively detected differences in lymphocyte DNA damage after feeding with the irradiated diet for 4 weeks. However, in order to ensure the safety of irradiated foods, it would be more useful to conduct a long-term feeding regimen using an irradiated diet and examine the level of lipid peroxidation and the state of oxidative stress in a greater range of organs.

• 제어로봇시스템학회:학술대회논문집
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• 1990.10a
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• pp.602-607
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• 1990

Spent nuclear fuel is very dangerous substance emitting strong ionizing radiation which is harmful to human body. The remote handling of spent nuclear fuel is essential because people cannot access this substance without protecting radiation. To handle highly radioactive material or nuclear waste, many kinds of teleoperators such as master slave manipulator, electro mechanical manipulator, servo manipulator, mobile robot was developed. The distance and dimension of target object cannot be measured easily when highly radioactive material is handled by teleoperator because one should use lead glass or TV camera and monitor to protect radiation and see target object. During experiments on the remote handling of spent nuclear fuel by electro mechanical manipulator, we often felt that a distance and dimension measurement system is necessary to handle the objects which is in the highly radioactive environment, so we developed a system which is appropriate for this purpose.

• Journal of Korean Library and Information Science Society
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• v.50 no.4
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• pp.635-658
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• 2019

In this study, the harmful factors measured in S university's central library were divided into ① air harmful substance ② biological harmful factors ③ carbon monoxide, carbon dioxide, and nitrogen dioxide concentration, measured and analyzed compared to the relevant criteria. The analysis showed that the harmful substances in the air - fine dust, asbestos, volatile organic compounds and formaldehyde - were all lower than the relevant standards, and that biological harmful factors such as fungi in the air, gramophageal bacteria, and endotoxin were also found to have no particular problems. The concentration of carbon monoxide, carbon dioxide, and nitrogen dioxide in the air was also maintained without any unusual factors compared to the concentration in the ordinary atmosphere. However, the library is a multi-use facility that needs regular cleaning and ventilation to manage the environment.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.99-100
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• 2003

The term allergy was originally defined by Clemens Yon Pirquet as ‘an altered capacity of the body to react to foreign substance’, which was an extremely board definition that included all immunological reactions. Allergy is now defined in a much more restricted manner as ‘disease following an immune response to an otherwise innocuous antigen’. Allergy is a member of a class of immune responses that have been termed hypersensitivity reactions; these are harmful immune responses that produce tissue injury and may cause serious disease. (omitted)

• Journal of Industrial Convergence
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• v.21 no.2
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• pp.79-84
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• 2023

This study was analyzed based on 1051 analyzes of questionnaires in order to examine the status and perception of abused drugs according to the gender of the young people entering the adult group from the adolescents. The gender of the young people who participated in the survey was 686 males and 365 females, and the types of abused drugs and their perceptions of harmful effects of narcotics and abused drugs were analyzed according to gender. As a result of the study, the experience of using alcohol, tobacco, appetite suppressants, sedatives, and opioid analgesics was statistically significant according to gender. Among the harmful effects of narcotic drugs and drugs of abuse, significant results were shown on the recognition of risks, induced problems, and sympathy for risks. As for the desirable way to improve the problem of narcotics and substance abuse, 257 women (68.2%) of women wanted publicity (enlightenment) activities, and about effective education for preventing narcotics and substance abuse, 379 men (54.2%) of men %) appeared as online online education. It is considered that proper education and publicity about drug use is necessary in the reality that drug addiction among young people due to drug abuse is increasing.

• Korean Journal of Environmental Agriculture
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• v.34 no.2
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• pp.139-148
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• 2015

BACKGROUND: The aim of this study was to isolate and identify algicidal bacterium that tends to kill the toxic dinoflagellate Alexandrium catenella, and to determine the algicidal activity and algicidal range of algicide. METHODS AND RESULTS: Among of algicidal bacteria isolated in this study, NH-3 isolate was the strongest algicidal activity against A. catenella. NH-3 isolate was identified on the basis of biochemical characteristics and analysis of 16S rRNA gene sequences. The NH-3 isolate showed over 99% homology with Arthrobacter oxydans, and was designated as Arthrobacter sp. NH-3. The optimal culture conditions were $25^{\circ}C$, initial pH 7.0, and 2.0% (w/v) NaCl concentration. The algicidal activity of Arthrobacter sp. NH-3 was significantly increased to maximum value in the late of logarithmic phase. Arthrobacter sp. NH-3 showed algicidal activity through indirect attack, which excreted active substance into the culture filtrate. When 10% culture filtrate of NH-3 was applied to A. catenella, 100% of algal cells were destroyed within 30 h. In addition, the algicidal activities were increased in dose and time dependent manners. The pure algicide was isolated from the ethyl acetate extract of the culture filtrate of NH-3 by using silica gel column chromatography and high performance liquid chromatography (HPLC). We investigated the algicidal activity of this algicide on the growth of harmful algal bloom (HAB) species, including A. catenella. As a result, it showed algicidal activity against several HAB species at a concentration of $100{\mu}g/mL$ and had a relatively wide host range. CONCLUSION: Taken together, our results suggest that Arthrobacter sp. NH-3 and its algicide could be a candidate for controlling of toxic and harmful algal blooms.

• Journal of Digital Convergence
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• v.16 no.4
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• pp.185-194
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• 2018

The purpose of this study was to understand the dental hygienist's perception of dental materials and to understand the safety status of harmful chemicals. The study was conducted from January to February 2015 for 250 dental hygienists working in Gwangju Metropolitan City. as a result, the degree of recognition of MSDS for dental materials was higher with age (P <0.05) and higher in dental hygienist (P <0.001) working at dental hospital. (P <0.001), and the factors affecting the perception of first aid treatment were positively correlated with experience of hazard education (P <0.001). Therefore, by understanding the MSDS awareness of dental materials by dental hygienists and the safety situation in the handling of hazardous chemical substances, we provide basic data for establishing proper recognition of safety in the handling of harmful chemical substances and developing educational programs to prevent accidents.

• Journal of Photoscience
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• v.7 no.3
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• pp.87-95
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• 2000

As sunlight not always optimized for every terrestrial plant in terms of light quality, quantity and duration, some plants suffer detrimental effects of sunlight exposure under certain conditions. Photoinhibition of photosynthesis is a typical phenomenon representing harmful light effects, commonly observed in many photosynthetic organisms. It is generally accepted that functional, structural loss of photosystem II complex(PSII) is the primary event of photoinhibition. Accumulating data also suggest that singlet oxygen($^1$O$_2$) is the main toxic species directly involved in it. There are two different views on the specific site and mechanism of $^1$O$_2$ production in the photosynthetic membrane. One of them favors the PSII reaction center, where the primary charge pairs recombination occurs as a prerequisite for the generation of $^1$O$_2$, and the other inclines to photosensitized $^1$O$_2$ formation by a substance located outside PSII. This article describes how we, as the advocators of the latter concept, have arrived at the conclusion that $^1$O$_2$ immediately involved in PSII photodamage is largely generated from the Rieske center of the cytochrome b$_{6}$/f complex and diffuses into PSII, attacking the reaction center subunits.s.

• Child Health Nursing Research
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• v.10 no.1
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• pp.108-116
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• 2004

Purpose: There has been a number of reports on elution of bisphenol-A, an endocrine disrupting chemical, from milk bottles, all concerning the potential health effect of the substance. In this study, we measured the elution of bisphenol-A from milk bottles during boiling-water sterilization, to suggest a safe sterilization method. Method: Through the survey of 200 mothers, 78.5％ of them expressed their concern on the possible harmful effect of bisphenol-A, which might be eluted from the bottles. And it was found that most mothers use boiling-water to sterilize bottles; duration of boiling bottles could be divided into three groups of 3, 5, and 10 minutes. We measured the elution of bisphenol- A from three different brands of bottles, subject to various mode of sterilization found in the survey. Result: In all the measurements, the concentration of the eluted bisphenol-A was in the range of 0.3 - 0.7 ppb, far below 2.5ppm, the level set up by Korea Food ％amp; Drug Administration(KFDA) for a potential harmful effect. Conclusion: Although trace amount of bisphenol -A can be eluted from polycarbonate milk bottles during sterilization, and bottle feeding, the amount is found to be too small to cause any health related impact for infants.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.5
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• pp.304-313
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• 2010

During recent years, various studies have demonstrated that indoor chemical pollution causes health problem and also negatively affect the performance of work by occupants. Building materials have been concerned as indoor chemical sources. Some of guidelines and certification system has been developed and resulted as dramatic decrease of harmful indoor chemicals such as formaldehyde and volatile organic compounds. Also, Home furniture and electrical devices has been concerned as one the primary influence the indoor chemical concentration in residential spaces. It is found that various kinds of electric home appliances have a significant source of chemical emission in indoor environments. In this study, the methodologies of detecting harmful chemicals from various kinds of products has been developed with large chamber measurement system and suggest some of the evaluation method for the chemicals from the home appliances as TV sets.